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What is Vecuronium Bromide
VecuroniumThe Generic name of this drug
Treatment SummaryVecuronium is a muscle relaxant used to temporarily weaken muscles during surgery. It is a type of non-depolarizing neuromuscular blocking agent that has a shorter duration of action than other similar drugs. Vecuronium is preferred to other muscle relaxants due to its minimal cardiovascular side effects, short duration of action, and the fact that it does not need to be eliminated by the kidneys.
Norcuronis the brand name
Vecuronium Bromide Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Norcuron
Vecuronium
1984
38
Approved as Treatment by the FDA
Vecuronium, also known as Norcuron, is approved by the FDA for 4 uses such as Intubation (procedure) and General Anesthesia .Intubation (procedure)
General Anesthesia
Used in combination with other therapies
Intubation (procedure)
Therapeutic procedure
Effectiveness
How Vecuronium Bromide Affects PatientsVecuronium is used to relax muscles during medical procedures. It works by blocking certain nerve signals from reaching the muscles, which causes them to relax.
How Vecuronium Bromide works in the bodyVecuronium blocks the transmission of nerve signals to muscles, preventing them from contracting. It does this by competing with acetylcholine for binding to special receptors on the surface of nerve cells. When vecuronium binds to these receptors, it prevents the release of calcium ions, which are necessary for muscle contraction.
When to interrupt dosage
The amount of Vecuronium Bromide hinges on the indicated condition, such as Intubation (procedure), Intubation (procedure) and smooth muscle relaxation prior to radiological procedures. The dose also differs as per the technique of delivery (e.g. Intravenous or Powder, for solution) delineated in the table beneath.Condition
Dosage
Administration
General Anesthesia
, 1.0 mg/mL, 2.0 mg/mL, 10.0 mg, 20.0 mg, 5.0 mg/mL
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Therapeutic procedure
, 1.0 mg/mL, 2.0 mg/mL, 10.0 mg, 20.0 mg, 5.0 mg/mL
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Intubation (procedure)
, 1.0 mg/mL, 2.0 mg/mL, 10.0 mg, 20.0 mg, 5.0 mg/mL
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Intubation (procedure)
, 1.0 mg/mL, 2.0 mg/mL, 10.0 mg, 20.0 mg, 5.0 mg/mL
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Warnings
There are 20 known major drug interactions with Vecuronium Bromide.Common Vecuronium Bromide Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Vecuronium may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Eluxadoline
Major
The risk or severity of constipation can be increased when Vecuronium is combined with Eluxadoline.
Ethanol
Major
Vecuronium may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Oliceridine
Major
The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Vecuronium is combined with Oliceridine.
Secretin human
Major
The therapeutic efficacy of Secretin human can be decreased when used in combination with Vecuronium.
Vecuronium Bromide Novel Uses: Which Conditions Have a Clinical Trial Featuring Vecuronium Bromide?
4 active studies are currently assessing the potential of Vecuronium Bromide for providing smooth muscle relaxation prior to radiological procedures, General Anesthesia and Intubation.Condition
Clinical Trials
Trial Phases
Intubation (procedure)
0 Actively Recruiting
General Anesthesia
3 Actively Recruiting
Not Applicable, Phase 3
Intubation (procedure)
0 Actively Recruiting
Therapeutic procedure
0 Actively Recruiting
Vecuronium Bromide Reviews: What are patients saying about Vecuronium Bromide?
1Patient Review
10/22/2008Patient Q&A Section about vecuronium bromide
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What would vecuronium be used for?
"This drug, which causes muscle paralysis, is often used to help with putting a tube down a patient's throat and making them relaxed during surgery when they are under general anesthesia."
Answered by AI
What is vecuronium made from?
"The vial contains 20 mg of Vecuronium bromide, 41.5 mg citric acid anhydrous, 32.5 mg dibasic sodium phosphate anhydrous, 194 mg mannitol, sodium hydroxide and/or phosphoric acid to buffer and adjust to a pH range of 3.5 to 4.5."
Answered by AI
What does vecuronium bromide do?
"Vecuronium bromide can be used to help with anesthesia, making it easier to put a tube down someone's throat and also providing muscle relaxation during surgery or when a machine is helping them breathe."
Answered by AI
What is another name for vecuronium?
"Vecuronium is a prescription medication that is used as general anesthesia. Vecuronium is available from various brands, such as Norcuron."
Answered by AI