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What is Fortaz
CeftazidimeThe Generic name of this drug
Treatment SummaryCeftazidime is an antibiotic used to treat bacterial infections. It belongs to a class of drugs called cephalosporins, which work by blocking the activity of enzymes that are necessary for the bacteria to build their cell walls. Ceftazidime is usually effective against even treatment-resistant bacteria such as Pseudomonas aeruginosa. The drug was approved by the FDA in 1985 and is available in combination with another drug called avibactam to help it work better.
Fortazis the brand name
Fortaz Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Fortaz
Ceftazidime
1989
59
Approved as Treatment by the FDA
Ceftazidime, also known as Fortaz, is approved by the FDA for 13 uses including Communicable Diseases and Gram Negative Bacteria .Communicable Diseases
Gram Negative Bacteria
Used to treat hospital-acquired bacterial pneumonia caused by susceptible Gram-negative microorganisms in combination with Avibactam
Urinary Tract Infection
Intraabdominal Infections
Bone and Joint Infections
Ventilator-associated Bacterial Pneumonia caused by susceptible Gram-negative microorganisms
Used to treat Ventilator-associated Bacterial Pneumonia caused by susceptible Gram-negative microorganisms in combination with Avibactam
Gram Negative Bacteria
Used to treat Complicated Urinary Tract Infections caused by susceptible Gram-negative microorganisms in combination with Avibactam
Gram Negative Bacteria
Used to treat susceptible Intra-Abdominal Infection caused by susceptible Gram-negative microorganism in combination with Avibactam
Communicable Diseases
Central Nervous System Infections
Bacterial Septicemia
Lower Respiratory Tract Infection (LRTI)
Urinary Tract Infection (UTI)
Effectiveness
How Fortaz Affects PatientsCeftazidime is an antibiotic used to treat a wide variety of bacterial infections. It is effective against most Gram-negative bacteria, such as _Pseudomonas aeruginosa_, and some Gram-positive bacteria, such as _Staphylococcus_ spp. and _Streptococcus_ spp. However, it is not effective against all bacteria, and care must be taken to use the right antibiotic for the right infection. Ceftazidime may cause serious allergic reactions, overgrowth of non-susceptible organisms, and _Clostridium difficile_-
How Fortaz works in the bodyCeftazidime is a type of antibiotic that works by blocking the action of certain enzymes in bacteria. These enzymes are responsible for forming, recycling, and remodeling the bacterial cell wall. By inhibiting these enzymes, ceftazidime disrupts the structure of the cell wall and kills the bacteria. It is effective against both Gram-positive and Gram-negative bacteria. In laboratory tests, ceftazidime has been shown to bind to several key enzymes in bacteria, including PBP3, PBP1a/1b, PBP2, and PonA1/2/A in Mycobacter
When to interrupt dosage
The measure of Fortaz is based on the determined condition, comprising Ventilator-associated Bacterial Pneumonia caused by vulnerable Gram-negative microbes, Complicated Skin and Soft Tissue Infection and Nosocomial Pneumonia. The dosage shifts, in agreement with the method of application as listed in the table beneath.Condition
Dosage
Administration
Gram Negative Bacteria
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
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Continuous ambulatory peritoneal dialysis therapy
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
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Gram Negative Bacteria
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, for solution, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Powder, Powder - Intramuscular; Intravenous
Lower Respiratory Tract Infection (LRTI)
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, for solution, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Powder, Powder - Intramuscular; Intravenous
Urinary tract infection
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
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Central Nervous System Infections
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, for solution, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Powder, Powder - Intramuscular; Intravenous
Complicated Skin and Soft Tissue Infection
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, for solution, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Powder, Powder - Intramuscular; Intravenous
Bronchopulmonary Infection
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
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Gram Negative Bacteria
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, for solution, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Powder, Powder - Intramuscular; Intravenous
Healthcare-Associated Pneumonia
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, for solution, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Powder, Powder - Intramuscular; Intravenous
Urinary Tract Infection (UTI)
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, for solution, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Powder, Powder - Intramuscular; Intravenous
Prostate
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
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Communicable Diseases
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, for solution, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Powder, Powder - Intramuscular; Intravenous
Malignant Neoplasms
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
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Bacteremia
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, for solution, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Powder, Powder - Intramuscular; Intravenous
Otitis Media
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
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Communicable Diseases
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, for solution, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Powder, Powder - Intramuscular; Intravenous
Urinary Tract Infection
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, for solution, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Powder, Powder - Intramuscular; Intravenous
Bone and Joint Infections
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, for solution, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Powder, Powder - Intramuscular; Intravenous
Cystic Fibrosis (CF)
100.0 mg/mL, 200.0 mg/mL, , 1000.0 mg, 2000.0 mg, 170.0 mg/mL, 20.0 mg/mL, 40.0 mg/mL, 56.0 mg/mL, 111.0 mg/mL, 600.0 mg/mL, 60.0 mg/mL, 6000.0 mg, 500.0 mg, 10000.0 mg, 3000.0 mg
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Warnings
Fortaz has one contraindication and must not be administered to any individual with any of the conditions outlined in the table below.Fortaz ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Common Fortaz Drug Interactions
Drug Name
Risk Level
Description
Neomycin
Major
The risk or severity of nephrotoxicity can be increased when Ceftazidime is combined with Neomycin.
Tenofovir
Major
Ceftazidime may increase the nephrotoxic activities of Tenofovir.
Tenofovir alafenamide
Major
Ceftazidime may increase the nephrotoxic activities of Tenofovir alafenamide.
Tenofovir disoproxil
Major
Ceftazidime may increase the nephrotoxic activities of Tenofovir disoproxil.
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Ceftazidime.
Fortaz Toxicity & Overdose RiskPatients with kidney problems may experience seizures, confusion, muscle spasms, and loss of consciousness if they overdose on ceftazidime. Those who suffer from an acute overdose should be carefully monitored and given supportive care. Kidney dialysis may help remove ceftazidime from the body.
Fortaz Novel Uses: Which Conditions Have a Clinical Trial Featuring Fortaz?
33 active studies are currently examining the capacity of Fortaz to treat Lower Respiratory Tract Infections (LRTI), Bronchopulmonary Infections and Gram Negative Bacterial Infections.Condition
Clinical Trials
Trial Phases
Bacteremia
12 Actively Recruiting
Not Applicable, Phase 4, Phase 1, Phase 2
Healthcare-Associated Pneumonia
0 Actively Recruiting
Intraabdominal Infections
4 Actively Recruiting
Not Applicable, Phase 4
Bacterial Septicemia
0 Actively Recruiting
Bronchopulmonary Infection
0 Actively Recruiting
Gram Negative Bacteria
0 Actively Recruiting
Bacterial Infections
0 Actively Recruiting
Otitis Media
0 Actively Recruiting
Cystic Fibrosis (CF)
0 Actively Recruiting
Urinary Tract Infection
8 Actively Recruiting
Not Applicable, Phase 4, Phase 3
Lower Respiratory Tract Infection (LRTI)
1 Actively Recruiting
Phase 3
Central Nervous System Infections
0 Actively Recruiting
Meningitis, Bacterial
0 Actively Recruiting
Peritoneal Dialysis
1 Actively Recruiting
Not Applicable
Communicable Diseases
0 Actively Recruiting
Fever
0 Actively Recruiting
Ventilator-associated Bacterial Pneumonia caused by susceptible Gram-negative microorganisms
0 Actively Recruiting
Continuous ambulatory peritoneal dialysis therapy
0 Actively Recruiting
Communicable Diseases
0 Actively Recruiting
Bone and Joint Infections
0 Actively Recruiting
Fortaz Reviews: What are patients saying about Fortaz?
4Patient Review
5/15/2011 My dog scratching me led to cellulitis, but this treatment has really helped. I've been taking it twice a day for 21 days and the infection seems to be gone now.
3Patient Review
1/24/2010 My mother is 87 years old, bedridden, and has a urinary tract infection caused by E-coli. She has been on Fortaz I.V. before and has had some problems with fever, rash, and pain in stomach. I have given her Benadryl for the rash, fever, and Tylenol for the pain.
Patient Q&A Section about fortaz
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Fortaz a penicillin?
"Ceftazidime is an antibiotic that belongs to the class of drugs known as cephalosporins. Cephalosporins are used to treat many different types of infections caused by bacteria. Ceftazidime is used to treat severe or life-threatening infections."
Answered by AI
What is another name for Fortaz?
"Ceftazidime is a cephalosporin antibiotic that is used to treat bacterial infections. It is sold under the brand name Fortaz among others."
Answered by AI
How is Fortaz given?
"The drug FORTAZ can be given intravenously or by injecting it deep into a large muscle, such as the upper outer quadrant of the gluteus maximus or lateral part of the thigh. Avoid injecting the drug into an artery (see PRECAUTIONS)."
Answered by AI
What is Fortaz used to treat?
"Fortaz is an antibiotic used to treat many kinds of bacterial infections, including severe or life-threatening forms."
Answered by AI