Fluocinolone Acetonide

Otitis Externa, Uveitis, Perianal erythema + 30 more

Treatment

3 FDA approvals

20 Active Studies for Fluocinolone Acetonide

What is Fluocinolone Acetonide

Fluocinolone acetonide

The Generic name of this drug

Treatment Summary

Fluocinolone acetonide is a medication used in topical creams and gels to reduce inflammation in skin conditions. It can also be found in implantable devices, made by Taro Pharmaceuticals, which were approved by the FDA in 2016.

Neo-Synalar

is the brand name

image of different drug pills on a surface

Fluocinolone Acetonide Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Neo-Synalar

Fluocinolone acetonide

1963

93

Approved as Treatment by the FDA

Fluocinolone acetonide, otherwise called Neo-Synalar, is approved by the FDA for 3 uses like Chronic Uveitis and Uveitis .

Chronic Uveitis

Uveitis

Uveitis

Effectiveness

How Fluocinolone Acetonide Affects Patients

Fluocinolone acetonide is a medicine used to reduce inflammation. When taken, it can constrict blood vessels and decrease the permeability of cells, as well as reduce the activity of the immune system. For its ophthalmic (eye-related) uses, fluocinolone acetonide is usually inserted directly into the eye. Clinical trials have shown that this medication can reduce the recurrence of eye inflammation over a 6-month period compared to those not treated with it. However, it is important to monitor eye pressure as this medication can increase it slightly.

How Fluocinolone Acetonide works in the body

Fluocinolone acetonide is a corticosteroid that works to reduce swelling, clotting, and other effects of inflammation. It binds to a receptor in the cell nucleus, which triggers the production of proteins that stop inflammation by blocking the release of an acid that helps create inflammatory molecules. This stops the inflammation process and helps reduce symptoms.

When to interrupt dosage

The measure of Fluocinolone Acetonide is conditioned by the acknowledged affliction, like Hemorrhoids, Perianal erythema and Itch. The magnitude of dosage varies as per the mode of delivery (e.g. Kit or Emulsion - Topical) mentioned in the following table.

Condition

Dosage

Administration

Skin

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

Conjunctivitis, Bacterial

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

Pressure Ulcer

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

Skin Inflammation caused by Bacterial Infections

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

Uveitis

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

Diabetic Macular Edema

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

Postoperative Care

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

Eczema

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

Dermatitis, Seborrheic

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

Otitis Externa

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

Uveitis

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

Otitis Media

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

Chronic disease

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

Surgery; Ear

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

postoperative treatment

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

Ear structure

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

Wound Infection

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

Perianal erythema

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

Scab

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

Itching

, 0.0001 mg/mg, 0.1 mg/mL, 0.00025 mg/mg, 0.11 mg/mL, 0.011 mg/mL, 0.0011 mg/mL, 0.01 %, 0.59 mg, 0.025 %, 0.19 mg, 0.0001 mg/mL, 0.25 mg/mL, 1.0 mg/mg, 0.18 mg, 0.625 mg/mL, 0.000003 mg/mg

, Topical, Cream, Cream - Topical, Ointment - Topical, Ointment, Solution, Solution - Topical, Kit, Oil, Auricular (otic), Oil - Auricular (otic), Oil - Topical, Kit - Topical, Solution - Auricular (otic), Implant, Implant - Intravitreal, Shampoo, Shampoo - Topical, Intravitreal, Solution / drops, Solution / drops - Auricular (otic), Gel - Topical, Emulsion - Topical, Emulsion, Intraocular, Implant - Intraocular, Gel

Warnings

Fluocinolone Acetonide Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Fluocinolone Acetonide may interact with conjunctiva

Mycoses

Do Not Combine

External auditory canal structure

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Fluocinolone Acetonide may interact with conjunctiva

There are 20 known major drug interactions with Fluocinolone Acetonide.

Common Fluocinolone Acetonide Drug Interactions

Drug Name

Risk Level

Description

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Fluocinolone acetonide is combined with 2-Methoxyethanol.

9-(N-methyl-L-isoleucine)-cyclosporin A

Major

The risk or severity of adverse effects can be increased when Fluocinolone acetonide is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

Abatacept

Major

The risk or severity of adverse effects can be increased when Fluocinolone acetonide is combined with Abatacept.

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Fluocinolone acetonide.

Abetimus

Major

The risk or severity of adverse effects can be increased when Fluocinolone acetonide is combined with Abetimus.

Fluocinolone Acetonide Toxicity & Overdose Risk

It is unknown if fluocinolone acetonide increases the risk of cancer or affects fertility. Other types of corticosteroids have been linked to genetic damage, but tests have shown that fluocinolone acetonide does not cause any genetic damage.

Fluocinolone Acetonide Novel Uses: Which Conditions Have a Clinical Trial Featuring Fluocinolone Acetonide?

97 active studies are being conducted to assess the potential of Fluocinolone Acetonide to mitigate Atopic Dermatitis, Otitis Media and Otitis Externa.

Condition

Clinical Trials

Trial Phases

Hemorrhoids

1 Actively Recruiting

Not Applicable

Perianal erythema

0 Actively Recruiting

Eczema

0 Actively Recruiting

Blister

0 Actively Recruiting

Otitis Externa

0 Actively Recruiting

Psoriasis of the scalp

1 Actively Recruiting

Phase 4

Otitis

3 Actively Recruiting

Not Applicable

Hemorrhoids

0 Actively Recruiting

Scab

0 Actively Recruiting

Ear structure

0 Actively Recruiting

Skin

0 Actively Recruiting

Skin Diseases

0 Actively Recruiting

Fissure in Ano

0 Actively Recruiting

Postoperative Care

5 Actively Recruiting

Early Phase 1, Phase 4, Not Applicable

Wound Infection

0 Actively Recruiting

Skin Inflammation caused by Bacterial Infections

0 Actively Recruiting

Uveitis

3 Actively Recruiting

Not Applicable, Phase 3

Conjunctivitis, Bacterial

0 Actively Recruiting

Coinfection

0 Actively Recruiting

Chronic disease

0 Actively Recruiting

Fluocinolone Acetonide Reviews: What are patients saying about Fluocinolone Acetonide?

5

Patient Review

10/12/2014

Fluocinolone Acetonide for Skin Rash that Becomes Thick & Discolored From Rubbing It

I had a terrible rash on my scalp that got worse and worse over the course of a year. I tried various treatments, but nothing worked. But then I started using fluocinolone oil and lotion, and it's almost entirely gone! And there's no more itching, which was driving me crazy.

5

Patient Review

10/12/2014

Fluocinolone Acetonide for Skin Rash that Becomes Thick & Discolored From Rubbing It

I've been battling a terrible rash on my scalp for over a year now, and it's only gotten worse despite trying various treatments. However, after just two weeks of using fluocinolone oil and lotion, the rash is almost entirely gone! And even better, there's no more itching which keeps my fingers away from the area. I'm hopeful that this is the end of the problem.

5

Patient Review

3/5/2008

Fluocinolone Acetonide for Anal Itching

5

Patient Review

3/5/2008

Fluocinolone Acetonide for Anal Itching

4.7

Patient Review

1/9/2020

Fluocinolone Acetonide for Atopic Dermatitis

It really helped relieve the itchiness I was experiencing all over my body.

4.7

Patient Review

1/9/2020

Fluocinolone Acetonide for Atopic Dermatitis

Itchy hands, arms, legs, and feet were all relieved after using this treatment.

4.3

Patient Review

10/14/2017

Fluocinolone Acetonide for Psoriasis of Scalp

I had no issues using this oil on my eyebrows or face; it went on smoothly with a cotton swab. I also didn't experience any burning or itching, which was great. My scalp was a different story though; at first I felt some mild burning sensations, but those quickly subsided within the week. After only eight days of treatment, I went from using it on my whole scalp to just spot-treating areas.

4.3

Patient Review

10/30/2007

Fluocinolone Acetonide for Inflammation of Skin caused by an Allergy

4.3

Patient Review

10/14/2017

Fluocinolone Acetonide for Psoriasis of Scalp

No issues using this oil on my eyebrows or face. It went on smoothly with a cotton swab and I experienced no burning or itching sensations. My scalp was another story though; I felt some mild burning at first, but it subsided after a week of continuous use. After only eight days total, I went from treating my whole scalp to just spot-treating problem areas.

4.3

Patient Review

10/30/2007

Fluocinolone Acetonide for Inflammation of Skin caused by an Allergy

4

Patient Review

9/4/2021

Fluocinolone Acetonide for Skin Inflammation

I've only been using this for a short while, but it's already done wonders for my itchiness and scaling.

4

Patient Review

9/4/2021

Fluocinolone Acetonide for Skin Inflammation

I've been using this treatment for a couple of days now as per my doctor's orders, and it has noticeably decreased the severe itching and thick scaling on my arms and legs due to an allergy.

3.7

Patient Review

8/21/2022

Fluocinolone Acetonide for seborrheic dermatitis of scalp

My doctor prescribed this for me due to a scalp condition. I don't use it the way the directions say, as my dermatologist wanted me not to rinse this out of my hair. I apply it twice daily, using only a small amount so as not to make my hair oily. I have thick, coarse, long curly hair. I use this in conjunction with another medication and it seems to be working. The only time I notice anything off is when I forget to use it or go too long without a proper wash.

3.7

Patient Review

5/13/2009

Fluocinolone Acetonide for Psoriasis of Scalp

So far, this medication is doing a great job at relieving the itching I've been experiencing.

3.7

Patient Review

8/21/2022

Fluocinolone Acetonide for seborrheic dermatitis of scalp

My doctor prescribed this for me due to a scalp condition. I don't use it the way the directions say - my dermatologist wanted me to not rinse it out of my hair. Twice a day, I apply a small amount so as not to make my hair oily. I have thick coarse long curly hair. In conjunction with another medication, this seems to be working well. The only time I notice anything off is when I forget to use it or go too long without a proper wash.

3.7

Patient Review

5/13/2009

Fluocinolone Acetonide for Psoriasis of Scalp

So far, this medication is doing a great job at relieving my itching. I'm hopeful that it will continue to be effective.

3

Patient Review

4/7/2009

Fluocinolone Acetonide for Psoriasis of Scalp

3

Patient Review

4/7/2009

Fluocinolone Acetonide for Psoriasis of Scalp

2.3

Patient Review

11/15/2009

Fluocinolone Acetonide for Anal Itching

It sometimes requires a few applications, but this definitely works for excema.

2.3

Patient Review

11/15/2009

Fluocinolone Acetonide for Anal Itching

It can take a few tries, but this cream really does work for eczema.

2

Patient Review

11/25/2020

Fluocinolone Acetonide for Psoriasis of Scalp

This product works somewhat, but it is messy to apply if you are using it on your scalp. It also stains bed linens and clothing. Oil stains do not come out easily, and if you have thicker hair, I am not sure that most of the product actually gets to your scalp.

2

Patient Review

11/25/2020

Fluocinolone Acetonide for Psoriasis of Scalp

While this product does work somewhat, it can be quite messy to apply if you're using it on your scalp. It also stains bedding and clothing, and if you have thicker hair, it's difficult to ensure that the product actually reaches your scalp.

2

Patient Review

6/6/2022

Fluocinolone Acetonide for Skin Inflammation

I was prescribed this treatment by my doctor for an inflamed, red scalp. After three weeks of use, I have yet to see any success.

2

Patient Review

6/6/2022

Fluocinolone Acetonide for Skin Inflammation

I was prescribed this medication by my doctor to help with an inflamed and red scalp. Unfortunately, even after using it for three weeks, I have yet to see any success.

1.7

Patient Review

1/16/2015

Fluocinolone Acetonide for Skin Rash that Becomes Thick & Discolored From Rubbing It

I have eczema and developed a patchy rash on my face from the friction of my glasses. I used this treatment for only one day, and it's slowly disappearing. Thank goodness, because it was on my face and looked horrible.

1.7

Patient Review

1/16/2015

Fluocinolone Acetonide for Skin Rash that Becomes Thick & Discolored From Rubbing It

I have eczema and developed a rash on my face from the friction of my glasses. I used this treatment for only one day, and it's slowly disappearing. Thank god, because it was on my face and looked horrible.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about fluocinolone acetonide

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is fluocinolone acetonide safe to use?

"Do not use fluocinolone cream over a long period of time, and do not use it on a large area of skin unless your doctor tells you to."

Answered by AI

Is fluocinolone acetonide an antifungal?

"No, fluocinonide is not an antifungal cream. It is a potent topical corticosteroid ("steroid") used to treat skin conditions such as plaque psoriasis, atopic dermatitis (eczema), or other steroid-responsive skin conditions."

Answered by AI

What is fluocinolone acetonide use for?

"Fluocinolone is a drug that is used to relieve discomfort caused by skin conditions. It is a corticosteroid, which is a type of medicine that is similar to cortisone. Fluocinolone is available in different forms, including a topical cream, an oil, and a shampoo. It is used to treat conditions such as psoriasis and seborrheic dermatitis."

Answered by AI

Does fluocinolone acetonide grow hair?

"Fluocinonide was applied to one half of the head while the other half was treated with the vehicle. Fluocinonide was occluded (wrapped with plastic or cloth) at night. Results showed that 54% of the treatment arm had hair regrowth compared to 0% in the vehicle group."

Answered by AI

Clinical Trials for Fluocinolone Acetonide

Image of Mass Eye and Ear in Boston, United States.

Probiotic Supplementation for Diabetic Macular Edema

18+
All Sexes
Boston, MA

In this pilot prospective, interventional, longitudinal study, we aim to evaluate the potential benefits of the probiotic supplement Lactobacillus plantarum 299v in patients with diabetic macular edema (DME). The study seeks to address the following questions: 1. Does central macular thickness on optical coherence tomography decrease after 4 months of supplementation? 2. Is visual acuity improved at 1, 2, 3, and 4 months following initiation of supplementation? 3. Is the number of anti-VEGF injections reduced following initiation of supplementation? Outcomes will be compared to a control group, using historic retrospective data. Participants will take Lactobacillus plantarum 299v orally twice daily for four months.

Phase 2
Waitlist Available

Mass Eye and Ear

Image of Johns Hopkins Bayview Medical Center in Baltimore, United States.

VR-Enhanced PMR for Post-Burn Symptoms

18+
All Sexes
Baltimore, MD

The goal of this clinical trial is to learn whether progressive muscle relaxation (PMR), delivered either alone or enhanced with virtual reality (VR), can help treat chronic symptom, such as pain, itch, anxiety, sleep disturbances, and fatigue, in adult burn survivors. The main questions it aims to answer are: * Does VR-enhanced PMR (VR-PMR) reduce chronic pain, anxiety, itch, sleep disturbances, and fatigue more effectively than standard PMR? * Is VR-PMR a feasible and acceptable self-administered home-based intervention for burn survivors? Researchers will compare two self-administered intervention conditions, VR-enhanced PMR and standard PMR, using a randomized to sequence crossover design to see if VR technology enhances the therapeutic effects of PMR on chronic symptom management in burn survivors. Participants will: * Complete home-based sessions of VR-enhanced PMR * Complete home-based sessions of standard PMR * Report symptoms such as pain, itch, anxiety, sleep disturbances, and fatigue throughout the study * Use VR equipment provided for the intervention period (during the VR-PMR arm)

Recruiting
Has No Placebo

Johns Hopkins Bayview Medical Center

Sheera Lerman Zohar, PhD

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Image of Dartmouth-Hitchcock Medical Center in Lebanon, United States.

Nutritional Shake for Postoperative Recovery

65+
All Sexes
Lebanon, NH

Older surgical patients commonly have malnutrition, and there is evidence these patients have increased risk for poor physical and brain recovery after surgery and anesthesia. There are scientific-based recommendations to provide nutritional supplements to support recovery. However, to date these recommendations do not address a broad group of nutrients likely to reverse common deficiencies. Team members have created a palatable, broad-spectrum and stable nutritional shake that we will give to patients after surgery. We propose to test the nutritional shake in frail older surgical patients at Dartmouth Health to determine if a nutrition shake provided after surgery improves recovery of physical function and cognitive abilities. Half the patients will receive the shake and the other will receive the standard of care postoperative nutritional instructions after surgery. We will collect information regarding physical function and cognitive abilities of all the patients while in the hospital and 90 days after surgery. We will use this data to apply for funding for a powered randomized trial to determine the role of nutrition in optimizing physical and cognitive recovery from surgery in older patients.

Recruiting
Has No Placebo

Dartmouth-Hitchcock Medical Center

Stacie G Deiner, MD

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Image of Associated Retinal Consultants PC in Phoenix, United States.

RO7446603 + Aflibercept/Faricimab for Diabetic Macular Edema

18+
All Sexes
Phoenix, AZ

This study aims to evaluate the ocular and systemic safety, tolerability and efficacy of RO7446603 in participants with diabetic macular edema (DME). The study consists of 2 segments: Phase I (Parts 1-4) and Phase II (Part 5). Phase I investigated the safety of RO7446603 following a single and multiple intravitreal (IVT) doses as monotherapy or co-administered with IVT aflibercept or IVT faricimab (in separate injections). Phase II will investigate the safety, tolerability, pharmacokinetics (PK) and efficacy of two dose levels of RO7446603 in combination with faricimab, with the two drugs co-mixed and administered as a single IVT injection, compared to faricimab alone. The first participant was enrolled in the Phase I segment on June 22, 2022. Phase I has been completed.

Phase 1 & 2
Recruiting

Associated Retinal Consultants PC (+69 Sites)

Clinical Trials

Genentech, Inc.

Image of Retinal Consultants of AZ, Ltd in Peoria, United States.

RO7497372 for Diabetic Macular Edema

18+
All Sexes
Peoria, AZ

This study will assess the safety and tolerability of RO7497372 in participants with DME. The study consists of 2 parts. Part 1 will test multiple-ascending doses of RO7497372 after unilateral intravitreal (IVT) administration in participants with DME. The main purpose of Part 1 is to provide data for RO7497372 safety and tolerability, as well as to characterize the ocular and systemic pharmacokinetics (PK), systemic anti-drug antibodies (ADA), and duration of target engagement, i.e., the pharmacodynamics (PD) in aqueous humor (AH) and blood. Part 2 will evaluate the safety, tolerability, PK, and PD of two dose strengths of RO7497372 (low dose and high dose), identified as safe and tolerated in Part 1.

Phase 1
Waitlist Available

Retinal Consultants of AZ, Ltd (+36 Sites)

Clinical Trials

Genentech, Inc.

Image of St. Michael's Hospital in Toronto, Canada.

Rectal Methadone for Postoperative Pain

18 - 65
All Sexes
Toronto, Canada

Patients undergoing spinal surgery require pain control medication after their surgery. Investigators have successfully used intravenous Methadone to manage pain after surgery. However, doctors in Canada do not have the intravenous form of Methadone to prescribe to their patients. The investigators in Canada propose a pilot trial to investigate whether Methadone administered rectally could be used to manage pain after spinal surgery. The main questions are: 1. Are investigators able to recruit participants for this trial and learn from this study to plan a larger trial? 2. Does Methadone administered rectally during surgery, reduce participants' pain intensity, use less pain medication, and have a better recovery after surgery? Investigators will compare Methadone to a placebo (a look-alike substance that contains no drug) to see if Methadone works to manage pain after surgery better than the usual pain management. Participants will: * receive either Methadone or placebo during surgery. * be asked some questions about their pain during days 1 to 3 after surgery * be contacted by phone to ask about their recovery At this time, the study aims to recruit 40 participants from St. Michael's Hospital, to learn whether it will be feasible to plan a larger study.

Phase 4
Recruiting

St. Michael's Hospital

Sergio Pereira, MD PhD

Image of University of Virginia in Charlottesville, United States.

Methadone vs Remifentanil for Pain in Craniotomy Surgery

18 - 65
All Sexes
Charlottesville, VA

Postoperative pain is prevalent after intracranial surgery. Patients undergoing craniotomy are typically managed with short acting opioids to enable early and reliable post-operative neurological exam as well as avoid the risk of respiratory depression. However, a plethora of studies have shown that a majority of these patients experience moderate to severe pain in first 48 hours after surgery. Suboptimal pain control can lead to complications such as arterial hypertension and post-operative intracranial hemorrhage, and hence, increased morbidity and mortality. Intravenous (IV) methadone has a long analgesic half-life and has N-methyl-D-aspartate (NMDA) receptor antagonist and serotonin and norepinephrine reuptake inhibitor (SNRI) properties. It has previously been shown to reduce postoperative opioid requirements, postoperative nausea and vomiting (PONV), and postoperative pain scores in patients that underwent orthopedic, abdominal, complex spine, and cardiac surgery. Similar findings have been shown in obstetric patients that underwent caesarean delivery under general anesthesia as well as patients that underwent gynecologic surgery and received IV methadone intraoperatively. In a recently published retrospective study, a single intraoperative dose of IV methadone was well tolerated with lower pain scores as well as MME (oral morphine milligram equivalents) requirements for up to 72 hours after elective intracranial surgery. IV methadone has, however, never been compared with conventional management via IV remifentanil for functional recovery in patients undergoing elective intercranial surgery. The investigator's hypothesis is that intravenous (IV) methadone is non-inferior to IV remifentanil in patients who undergo elective intracranial surgery. It offers the advantage of being a single dose noninvasive analgesic modality that may contribute to decreasing MME consumption during the first 72 hours postoperatively, controlling postoperative pain, and improving quality of recovery after surgery.

Phase < 1
Waitlist Available

University of Virginia

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