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What is Solosec
SecnidazoleThe Generic name of this drug
Treatment SummarySecnidazole is a medication for bacterial infections. It is used to treat bacterial vaginosis, a common vaginal infection in women aged 15 to 44. It works by selectively targeting certain bacteria and protozoa that cause infections. It was approved by the FDA in 2017 under the brand name Solosec and is taken as one single dose.
Solosecis the brand name
Solosec Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Solosec
Secnidazole
2017
3
Effectiveness
How Solosec Affects PatientsSecnidazole is an antibiotic used to treat a variety of bacterial and protozoal infections. It works by targeting certain anaerobic bacteria and parasites, like Bacteroides fragilis, Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia. Taking secnidazole may slightly increase the length of your heart's electrical cycle, but it is not considered to be harmful.
How Solosec works in the bodySecnidazole works by releasing reactive molecules when they enter a pathogen. These molecules damage the DNA of the pathogen, preventing it from reproducing and leading to its death. This type of drug is very effective against Gram positive bacteria, Gram negative bacteria, and _T. vaginalis_.
When to interrupt dosage
The proposed measure of Solosec is contingent upon the identified affliction, for example Trichomoniasis, Bacterial Vaginosis and Trichomonas Vaginitis. The dose likewise changes as indicated by the technique of conveyance (e.g. Oral or Granule - Oral) featured in the table beneath.Condition
Dosage
Administration
Bacterial Vaginosis
, 2.0 mg/mg
, Oral, Granule, Granule - Oral
Trichomonas Vaginitis
, 2.0 mg/mg
, Oral, Granule, Granule - Oral
Yeast Infection
, 2.0 mg/mg
, Oral, Granule, Granule - Oral
Warnings
Solosec has one contraindication. If you have any of the conditions listed in the table below, it should not be taken in tandem with Solosec.Solosec ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Secnidazole may interact with Pulse Frequency
Common Solosec Drug Interactions
Drug Name
Risk Level
Description
Solosec Toxicity & Overdose RiskThere is no available data on the toxic dose or overdose of secnidazole.
Solosec Novel Uses: Which Conditions Have a Clinical Trial Featuring Solosec?
10 active clinical trials are currently in progress to assess the utility of Solosec in providing relief from Trichomoniasis, Bacterial Vaginosis and Trichomonas Vaginitis.Condition
Clinical Trials
Trial Phases
Yeast Infection
6 Actively Recruiting
Phase 1, Phase 2, Phase 3, Early Phase 1, Not Applicable
Bacterial Vaginosis
3 Actively Recruiting
Not Applicable, Phase 2, Early Phase 1
Trichomonas Vaginitis
1 Actively Recruiting
Phase 2
Solosec Reviews: What are patients saying about Solosec?
5Patient Review
3/29/2020 While the taste is certainly not great, it's manageable. I would recommend drinking it with a smoothie or something similar to help mask the flavor. So far, no side effects!
4.7Patient Review
8/8/2021 Even though this medication tasted terrible, it was worth it because my problem cleared up within a day. I've tried other medications like Flagyl and Clindeese, but neither of them worked. This is been ongoing for months and I think this medication finally did the trick. Hopefully it stays gone.
4.7Patient Review
5/28/2020 The taste was really tough to get over, but the medication itself is effective. I'm not sure if there are other options out there that might be more pleasant, but I'll definitely be asking my doctor about it.
4.7Patient Review
7/23/2020 I read the reviews before taking this, which was helpful. I learned that alcohol shouldn't be consumed while on this medication, so I haven't had a drink and won't for the duration of the treatment. The taste is bitter but tolerable; mixing it with non-dairy yogurt helps. On day two now and feeling fine--no side effects to speak of yet. Fingers crossed it works!
3.7Patient Review
3/14/2020 It was unpleasant, but it did the job it intended to. Unfortunately, it may have done too good of a job as I'm now quite dried out.
3Patient Review
6/18/2020 I was a first time user and sprinkled the medication on top of vanilla yogurt. The taste was bitter, but the yogurt helped. I then drank a glass of water; however, the taste lingered. That evening, I had one glass of wine and felt very sick afterwards (nauseous and dizzy). It's possible that my reaction is due to my small stature (5'2" and 108 lbs)? Or maybe because I don't drink often? Either way, I still don't feel great this morning--there's also been some discharge over 24 hours later.
2.7Patient Review
7/20/2020 The first time I took this medication, I made the mistake of mixing it with applesauce and ended up vomiting. It also has a terrible metallic taste. My doctor gave me two samples, but due to Covid-19, I didn't want to go to the office so I decided to try again. This time, I made a smoothie with a lot of fruits, spinach, yogurt almond milk and ginger to mask the taste. You have to mix it well and swallow it whole.
2Patient Review
1/17/2020 Mixing it in chocolate pudding makes it more palatable. I saw some improvement after the first day, but by Day 5 I was back at square one.
1Patient Review
2/25/2020 Do not take this medication if you plan on consuming alcohol. I had a very unpleasant experience of vomiting for five hours straight after only two glasses of wine.
Patient Q&A Section about solosec
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Does SOLOSEC cure BV?
"Solosec is not approved to prevent BV, only to treat it. It is not known if it is safe to use to prevent infections, which might cause Solosec and other similar medications to not work well in treating future infections."
Answered by AI
What is SOLOSEC used for?
"- The U.S. Food and Drug Administration (FDA) has approved SOLOSEC (secnidazole) 2 g oral granules for the treatment of bacterial vaginosis in female patients 12 years of age and older and trichomoniasis in patients 12 years of age and older.
SOLOSEC is a medication indicated for the treatment of bacterial vaginosis and trichomoniasis. It is available in the form of oral granules. The granules should be taken twice a day for four consecutive days. The recommended dosage for adults is 2 g per day. For children weighing less than 50 kg, the recommended dosage is 1 g per day."
Answered by AI
How long does it take SOLOSEC to work?
"A statistically significant greater percentage of patients experienced clinical response, Nugent score cure, and therapeutic response when taking SOLOSEC compared to placebo, based on data from both trials. These results were achieved at Day 7-14 in Trial 2, and at 21 to 30 days following a single dose of SOLOSEC in both trials."
Answered by AI
Does SOLOSEC treat yeast infection?
"People should avoid having sex until they and their sex partners are treated for trichomoniasis. This will help prevent reinfection. Secnidazole will not treat fungal (yeast) infections."
Answered by AI