Desoximetasone

Skin Diseases, Dermatitis, Allergic Contact, Psoriasis Vulgaris + 1 more
Treatment
20 Active Studies for Desoximetasone

What is Desoximetasone

DesoximetasoneThe Generic name of this drug
Treatment SummaryGlucocorticoids are a type of topical anti-inflammatory medication used to treat skin conditions such as dermatitis, allergies, and psoriasis.
Desoximetasoneis the brand name
Desoximetasone Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Desoximetasone
Desoximetasone
1985
66

Effectiveness

How Desoximetasone Affects PatientsDesoximetasone is a type of medication that helps reduce inflammation and itching when applied to the skin. It is a strong topical corticosteroid and should not be used with any type of bandage or covering. Treatment with desoximetasone should not last longer than two weeks, and should be stopped once the desired results have been achieved.
How Desoximetasone works in the bodyTopical steroids work to reduce inflammation, but the exact way they do this is not known. It is believed that steroids act by stimulating the production of proteins that block the release of arachidonic acid, a precursor to inflammation-causing molecules like prostaglandins and leukotrienes. Steroids also bind to glucocorticoid receptors, which then travel to the nucleus and bind to DNA to start the production of these proteins.

When to interrupt dosage

The advocated dose of Desoximetasone is contingent upon the determined condition, including Atopic Dermatitis, corticosteroid-responsive dermatoses and Psoriasis. The amount of dosage fluctuates as per the technique of delivery (e.g. Topical or Cream - Topical) mentioned in the following table.
Condition
Dosage
Administration
Skin Diseases
0.0025 mg/mg, , 0.0005 mg/mg, 2.5 mg/mL, 0.05 %, 0.25 %
Topical, , Ointment, Cream, Cream - Topical, Gel - Topical, Gel, Ointment - Topical, Spray, Emulsion, Emulsion - Topical, Spray - Topical
Psoriasis Vulgaris
0.0025 mg/mg, , 0.0005 mg/mg, 2.5 mg/mL, 0.05 %, 0.25 %
Topical, , Ointment, Cream, Cream - Topical, Gel - Topical, Gel, Ointment - Topical, Spray, Emulsion, Emulsion - Topical, Spray - Topical
Psoriasis
0.0025 mg/mg, , 0.0005 mg/mg, 2.5 mg/mL, 0.05 %, 0.25 %
Topical, , Ointment, Cream, Cream - Topical, Gel - Topical, Gel, Ointment - Topical, Spray, Emulsion, Emulsion - Topical, Spray - Topical
Dermatitis, Allergic Contact
0.0025 mg/mg, , 0.0005 mg/mg, 2.5 mg/mL, 0.05 %, 0.25 %
Topical, , Ointment, Cream, Cream - Topical, Gel - Topical, Gel, Ointment - Topical, Spray, Emulsion, Emulsion - Topical, Spray - Topical

Warnings

There are 20 known major drug interactions with Desoximetasone.
Common Desoximetasone Drug Interactions
Drug Name
Risk Level
Description
2-Methoxyethanol
Major
The risk or severity of adverse effects can be increased when Desoximetasone is combined with 2-Methoxyethanol.
9-(N-methyl-L-isoleucine)-cyclosporin A
Major
The risk or severity of adverse effects can be increased when Desoximetasone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Abatacept
Major
The risk or severity of adverse effects can be increased when Desoximetasone is combined with Abatacept.
Abetimus
Major
The risk or severity of adverse effects can be increased when Desoximetasone is combined with Abetimus.
Acteoside
Major
The risk or severity of adverse effects can be increased when Desoximetasone is combined with Acteoside.
Desoximetasone Toxicity & Overdose RiskToo much desoximetasone applied to the skin can be absorbed and cause systemic effects. Overdosing on this drug may lead to thinning of the skin and reduced ability of the adrenal cortex to respond to stress.
image of a doctor in a lab doing drug, clinical research

Desoximetasone Novel Uses: Which Conditions Have a Clinical Trial Featuring Desoximetasone?

88 active trials are presently evaluating the potential of Desoximetasone to mitigate the symptoms of Psoriasis, Atopic Dermatitis and Plaque Psoriasis.
Condition
Clinical Trials
Trial Phases
Dermatitis, Allergic Contact
0 Actively Recruiting
Skin Diseases
0 Actively Recruiting
Psoriasis Vulgaris
23 Actively Recruiting
Early Phase 1, Phase 3, Not Applicable, Phase 2, Phase 4, Phase 1
Psoriasis
0 Actively Recruiting

Desoximetasone Reviews: What are patients saying about Desoximetasone?

5Patient Review
4/30/2011
Desoximetasone for Skin Condition
This medication quickly and effectively removed the redness on my legs. The only downside is that now my leg hair is growing back very rapidly!
5Patient Review
12/20/2017
Desoximetasone for Inflammation of Skin caused by an Allergy
This was the only medication that addressed my son's eczema. We've used it, off and on, for the past five years as needed. I find that I need to use less than what is prescribed; my son has been using it for so long now that his body may be resistant to it. He is currently taking Fluticasone. This medicine provided much-needed relief from the constant itching all over his body for those five years. Let's hope the new prescription will work just as well!
5Patient Review
9/6/2016
Desoximetasone for Atopic Dermatitis
We've tried a lot of different treatments for my son's dermatitis, and this is by far the best one. A couple days of application is all it takes to make the symptoms disappear.
5Patient Review
11/19/2017
Desoximetasone for Contact Dermatitis
This medication doesn't have propylene glycol, which is great because other topical creams/ointments I've used that did contain it made my skin condition worse. Topicort helped immediately and now I only use it as needed.
5Patient Review
1/26/2011
Desoximetasone for Skin Rash that Becomes Thick & Discolored From Rubbing It
This medication is great for occasional poison ivy and oak outbreaks. It relieves itching and prevents the rash from spreading. I also use it with Tecnu poison ivy and oak oil remover soap, which works really well!
5Patient Review
4/26/2010
Desoximetasone for Contact Dermatitis
This treatment really helped me. I'm grateful for modern medicine.
5Patient Review
4/15/2011
Desoximetasone for Rash
Used it for clearing up Canker Sores. Worked well and quickly.
5Patient Review
10/28/2018
Desoximetasone for Atopic Dermatitis
I had a nasty rash that was both itchy and burning. It was on my lower back, both sides of my knees, the back of my forearms, back of my neck, under my shoulder straps etc After 7 months of no relief, I was given DESOXIMETASONE and it works!
4.7Patient Review
7/11/2010
Desoximetasone for Atopic Dermatitis
This medicine was highly effective in treating my eczema; however, I developed stretch marks as an unfortunate side effect. These are now permanent reminders of the period of my life when I had to deal with eczema.
4.7Patient Review
4/15/2010
Desoximetasone for Contact Dermatitis
4Patient Review
8/27/2013
Desoximetasone for Skin Condition
I could tell a difference within just a few days of taking this medication. My itching improved and I was able to sleep better at night, which was a huge relief. Overall, I'm very pleased with the results.
4Patient Review
8/2/2010
Desoximetasone for Reddish Nodules Arranged in a Circle On the Skin
I was very hesitant to use this treatment after reading some reviews, but I'm glad that I did. Within 24 hours, my poison ivy rash was almost gone. This medicine is extremely effective and I have had no side effects.
3.7Patient Review
6/15/2022
Desoximetasone for Atopic Dermatitis
I've used this cream around 20 times and have found that the tube gets punctured from the sides when you try to squeeze it from the bottom. This happens after a few uses, when there's some space in the tube. I think the material used to make the tube packing is not good quality. I raised this issue with the manufacturer of this drug and provided them with a sample tube for quality control, but they haven't responded. I also contacted FDA but no answer.
3Patient Review
6/11/2011
Desoximetasone for Reddish Nodules Arranged in a Circle On the Skin
I've had this disease for a long time, and it's gotten pretty bad. That said, I don't think this cream is very effective because it takes a while to absorb.
3Patient Review
3/16/2010
Desoximetasone for Osteoporosis
3Patient Review
3/16/2010
Desoximetasone for Atopic Dermatitis
2Patient Review
2/8/2013
Desoximetasone for Atopic Dermatitis
I have not found this topical to be effective. If anything, my condition has only gotten worse since using it.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about desoximetasone

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is desoximetasone a strong steroid?

"Desoximetasone is one of the strongest topical steroid medications, though it is not as strong as the spray. The strongest steroid creams, according to the National Psoriasis Foundation, include clobetasol, halobetasol, or fluocinonide."

Answered by AI

What is desoximetasone cream used for?

"Desoximetasone topical is a corticosteroid medication used to relieve redness, itching, swelling, or other discomfort caused by skin conditions. It is available as a cream, ointment, or spray. Desoximetasone topical spray is specifically approved for the treatment of plaque psoriasis."

Answered by AI

Is desoximetasone cream good for eczema?

"Desoximetasone topical is used to treat the symptoms of various skin conditions, including psoriasis and eczema."

Answered by AI

Clinical Trials for Desoximetasone

Have you considered Desoximetasone clinical trials? We made a collection of clinical trials featuring Desoximetasone, we think they might fit your search criteria.Go to Trials
Image of Lynderm Research in Markham, Canada.

ESK-001 for Plaque Psoriasis

18+
All Sexes
Markham, Canada
The objective of the ESK-001-018 long term extension is to evaluate the safety and efficacy of ESK-001 over time. The scientific questions it aims to answer are: * How safe is taking ESK-001 long-term in people with moderate to severe plaque psoriasis? * Does taking ESK-001 long-term reduce the severity of people's plaque psoriasis? Patients will enter the long-term extension study following completion of one of the parent studies (ESK-001-016 or ESK-001-017) and will receive open-label ESK-001 twice daily for 24 weeks. After 24 weeks, the first 200 patients meeting at least PASI-75 clinical response will be randomly assigned to receive ESK-001 or placebo. At any point during this time, the patients losing the initial clinical response may return to the open-label ESK-001 treatment. Patients who complete Week 48 will return to open-label ESK-001 treatment and they will receive ESK-001 until the end of the study or discontinuation. All the remaining patients not meeting the entry criteria for the randomized withdrawal phase will continue to receive open-label ESK-001 for the remainder of the study. Patients taking part in the study must be men or women aged at least 18 years old and have completed a previous (parent) study of ESK-001 in moderate to severe plaque psoriasis. Patients must consent and agree to: * ensure drug daily compliance until end of study or discontinuation. * visit the clinic for checkups and assessments. * provide blood and urine samples.
Phase 3
Recruiting
Quick Reply
Lynderm Research (+35 Sites)Alumis Inc
Image of Not posted in Webster, United States.

IRX4204 for Plaque Psoriasis

18+
All Sexes
Webster, TX
The goal of this clinical trial is to learn if IRX4204 works to treat plaque psoriasis in adults. It will also learn about the safety of IRX4204. The main questions it aims to answer are: * Does IRX4204 treat plaque psoriasis symptoms? * Does IRX4204 treat plaque psoriasis symptoms better than someone who is not being treated? * What medical problems do participants have when taking IRX4204? Researchers will compare IRX4204 to a placebo (a look-alike substance that contains no drug) to see if the drug works to treat mild to moderate plaque psoriasis. Participants will: * Take IRX4204 every day for 28 days * Visit the clinic once every week for checkups and tests * Complete specific assessments about plaque psoriasis and changes to plaques
Phase 2
Waitlist Available
Not postedIo Therapeutics
Have you considered Desoximetasone clinical trials? We made a collection of clinical trials featuring Desoximetasone, we think they might fit your search criteria.Go to Trials
Have you considered Desoximetasone clinical trials? We made a collection of clinical trials featuring Desoximetasone, we think they might fit your search criteria.Go to Trials
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