Aristocort

Macular Edema, Stomatitis, Denture, Ophthalmia, Sympathetic + 113 more

Treatment

16 FDA approvals

20 Active Studies for Aristocort

Treatment for

Macular Edema

What is Aristocort

TriamcinoloneThe Generic name of this drug

Treatment SummaryTriamcinolone is a steroid used to treat various types of inflammation, from allergies to multiple sclerosis. It can be used as a one-time treatment for knee pain related to arthritis, or as a topical treatment for skin conditions. There are several forms of triamcinolone, including hexacetonide, acetonide, and diacetate. Triamcinolone was approved by the FDA in 1957, and in 2021 a suspension of triamcinolone acetonide was approved for suprachoroidal injection to treat macular edema associated with uveitis.

Aristocortis the brand name

image of different drug pills on a surface

Aristocort Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Aristocort

Triamcinolone

1961

532

Approved as Treatment by the FDA

Triamcinolone, also called Aristocort, is approved by the FDA for 16 uses which include Lichen Planus and Ganglia .

Lichen Planus

Helps manage Lichen Planus (LP)

Ganglia

Helps manage cystic tumour of the ganglia

Granuloma Annulare

Helps manage granuloma annulare lesions

Psoriasis

Helps manage Psoriatic plaque

Neurodermatitis

Helps manage Lichen simplex chronicus

Lupus Erythematosus, Discoid

Helps manage Discoid Lupus Erythematosus (DLE)

granuloma annulare lesions

Helps manage granuloma annulare lesions

cystic tumour of the ganglia

Helps manage cystic tumour of the ganglia

Lichen simplex chronicus

Helps manage Lichen simplex chronicus

Lichen Planus (LP)

Helps manage Lichen Planus (LP)

Discoid Lupus Erythematosus (DLE)

Helps manage Discoid Lupus Erythematosus (DLE)

Alopecia Areata (AA)

Helps manage Alopecia Areata (AA)

Keloids Scars

Helps manage Keloids Scars

Necrobiosis Lipoidica

Helps manage Necrobiosis lipoidica diabeticorum

Alopecia Areata

Helps manage Alopecia Areata (AA)

Psoriatic plaque

Helps manage Psoriatic plaque

Effectiveness

How Aristocort Affects PatientsTriamcinolone is a type of medication which reduces inflammation in many areas of the body. It should not be injected directly into the spine.

How Aristocort works in the bodyTriamcinolone helps reduce inflammation. It does this by limiting the breakdown of cell membranes which prevents the formation of certain acids. These acids are responsible for producing signals that cause inflammation. Triamcinolone also helps by making blood vessels less wide, and reducing the number of cells that flow to sites of inflammation.

When to interrupt dosage

The advised portion of Aristocort is contingent upon the determined condition, including Mycosis Fungoides (MF), Mycoses and Alopecia Areata (AA). The amount of dosage fluctuates as per the technique of delivery (e.g. Ointment or Injection, suspension - Intralesional; Parenteral) featured in the table beneath.

Condition

Dosage

Administration

Stomatitis, Denture

, 40.0 mg/mL, 10.0 mg/mL, 0.055 mg, 0.001 mg/mg, 0.25 mg/mL, 1.0 mg/mL, 0.0005 mg/mg, 0.00025 mg/mg, 0.005 mg/mg, 5.0 mg/mL, 20.0 mg/mL, 0.000147 mg/mg, 0.5 mg/mL, 40.0 mg, 1.0 mg, 0.000025 mg/mg, 0.1 %, 0.025 %, 5.0 mg, 0.25 mg, 2.0 mg, 4.0 mg, 0.5 %, 15.0 mg/mL, 6.5 mg, 80.0 mg/mL, 0.075 mg, 200.0 mg/mL, 32.0 mg, 0.055 mg/dose, 0.5 mg, 0.2 mg/pump actuation, 0.1 mg/dose, 25.0 mg/mL, 0.055 mg/pump actuation, 2.0 mg/mL, 0.4 mg/mL

Injection, suspension, Intra-articular; Intramuscular, Injection, suspension - Intra-articular; Intramuscular, , Injection, suspension - Intra-articular; Intralesional, Intra-articular; Intralesional, Nasal, Spray, metered, Spray, metered - Nasal, Topical, Lotion, Lotion - Topical, Cream, Cream - Topical, Ointment, Ointment - Topical, Intralesional; Parenteral, Injection, suspension - Intralesional; Parenteral, Intra-articular; Parenteral, Injection, suspension - Intra-articular; Parenteral, Intra-articular; Intrabursal; Intradermal; Intralesional, Injection, suspension - Intra-articular; Intrabursal; Intradermal; Intralesional, Aerosol, spray, Aerosol, spray - Topical, Paste, Paste - Topical, Intramuscular, Injection, suspension - Intramuscular, Dental, Paste - Dental, Suspension - Intra-articular; Intramuscular, Suspension - Intra-articular; Intrabursal; Intradermal; Intrasynovial, Suspension, Suspension - Intra-articular; Intrabursal; Intramuscular, Intra-articular; Intrabursal; Intramuscular, Intralesional, Suspension - Intralesional, Aerosol, metered, Aerosol, metered - Nasal, Aerosol, metered - Respiratory (inhalation), Suspension - Intra-articular, Intra-articular, Tablet, Tablet - Oral, Oral, Intra-articular; Intramuscular; Intrasynovial, Liquid, Syrup - Oral, Liquid - Intra-articular; Intradermal; Intramuscular, Syrup, Kit, Spray, suspension - Nasal, Injection, solution, Injection, solution - Intra-articular; Intramuscular, Epidural; Infiltration; Intra-articular; Intramuscular; Topical, Ophthalmic, Intravitreal, Infiltration; Intra-articular; Intramuscular; Respiratory (inhalation); Topical, Kit - Infiltration; Intra-articular; Intramuscular; Respiratory (inhalation); Topical, Intra-articular; Intrabursal; Intradermal; Intrasynovial, Respiratory (inhalation), Liquid - Intra-articular; Intramuscular; Intrasynovial, Intra-articular; Intradermal; Intramuscular, Suspension - Intramuscular, Intra-articular; Intradermal; Intralesional; Intramuscular, Suspension - Intra-articular; Intradermal; Intralesional; Intramuscular, Kit - Epidural; Infiltration; Intra-articular; Intramuscular; Topical, Injection, suspension - Ophthalmic, Suspension - Intravitreal, Spray - Topical, Spray, Intra-articular; Intrasynovial; Periarticular, Suspension - Intra-articular; Intrasynovial; Periarticular, Kit - Intra-articular; Intramuscular, Suspension - Ophthalmic, Subcutaneous, Implant - Subcutaneous, Injection, suspension - Intra-articular; Intramuscular; Intravitreal, Intra-articular; Intramuscular; Intravitreal, Epidural; Infiltration; Intra-articular; Intramuscular, Kit - Epidural; Infiltration; Intra-articular; Intramuscular, Epidural; Intra-articular; Intramuscular; Topical, Kit - Epidural; Intra-articular; Intramuscular; Topical, Injection, suspension - Intra-articular; Intralesional; Intramuscular; Intrasynovial; Parenteral, Epidural; Infiltration; Intra-articular; Intralesional, Kit - Epidural; Infiltration; Intra-articular; Intralesional, Intra-articular; Intralesional; Intramuscular; Intrasynovial; Parenteral, Kit - Intra-articular, Paste, dentifrice - Dental, Paste, dentifrice, Kit - Infiltration; Soft tissue; Topical, Infiltration; Soft tissue; Topical, Implant, Ointment - Buccal, Buccal, Emulsion, Gel, Gel - Topical, Emulsion - Topical, Intra-articular; Intramuscular; Topical, Kit - Topical, Injection, suspension - Intra-articular, Infiltration; Intra-articular; Intramuscular; Topical, Kit - Infiltration; Intra-articular; Intramuscular; Topical

Hypercalcemia

Adrenal Insufficiency

induction of Diuresis

Neurodermatitis

Intertrigo

Proteinuria

Tenosynovitis

Bullous dermatitis herpetiformis

cutaneous candidiasis

Neurodermatitis

Ganglia

Atopic Dermatitis

Vitrectomy therapy

Skin Diseases

Granuloma Annulare

Sarcoidosis

Eosinophilic Pneumonia

Thyroiditis

Hemangioma

Warnings

Aristocort has four contraindications. It should not be taken in case of any of the conditions found in the table below.Aristocort Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Triamcinolone may interact with Pulse Frequency

Mycoses

Do Not Combine

active periocular infections

Do Not Combine

Eye Infections

Do Not Combine

There are 20 known major drug interactions with Aristocort.

Common Aristocort Drug Interactions

Drug Name

Risk Level

Description

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Triamcinolone is combined with 2-Methoxyethanol.

9-(N-methyl-L-isoleucine)-cyclosporin A

Major

The risk or severity of adverse effects can be increased when Triamcinolone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Triamcinolone.

Abetimus

Major

The risk or severity of adverse effects can be increased when Triamcinolone is combined with Abetimus.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be increased when combined with Triamcinolone.

Aristocort Toxicity & Overdose RiskThe lowest toxic dose of triamcinolone acetonide for rats is 13,100µg/kg and 132mg/kg for mice. In rats, the lowest toxic dose is 1451mg/kg and 2168mg/kg in mice. When administered through the abdomen, the lowest toxic dose is 105mg/kg in mice. Those who overdose on triamcinolone acetonide may develop Cushing's syndrome, which can be treated with supportive therapy and mifepristone.

Aristocort Novel Uses: Which Conditions Have a Clinical Trial Featuring Aristocort?

Currently, 1076 active trials are examining the potential of Aristocort to provide relief from Lupus, Atopic Dermatitis and Brain Metastases.

Condition

Clinical Trials

Trial Phases

Macular Edema

1 Actively Recruiting

Phase 2

Inflammation

59 Actively Recruiting

Not Applicable, Early Phase 1, Phase 1, Phase 2, Phase 3, Phase 4

Asthma

92 Actively Recruiting

Phase 1, Phase 4, Early Phase 1, Phase 2, Not Applicable, Phase 3

Anemia, Hemolytic, Autoimmune

0 Actively Recruiting

Rheumatoid Arthritis

55 Actively Recruiting

Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1

Vitrectomy therapy

0 Actively Recruiting

Dermatitis, Seborrheic

0 Actively Recruiting

Thyroiditis

0 Actively Recruiting

Brain

0 Actively Recruiting

Stomatitis

0 Actively Recruiting

Dermatitis

0 Actively Recruiting

Crohn's Disease

54 Actively Recruiting

Phase 1, Phase 2, Not Applicable, Phase 3, Phase 4, Early Phase 1

Tinea

0 Actively Recruiting

Conjunctivitis, Bacterial

0 Actively Recruiting

Tenosynovitis

0 Actively Recruiting

Mycoses

0 Actively Recruiting

Synovitis

1 Actively Recruiting

Phase 4

Dermatitis, Allergic Contact

0 Actively Recruiting

Keloids Scars

0 Actively Recruiting

Ulcer

0 Actively Recruiting

Aristocort Reviews: What are patients saying about Aristocort?

5Patient Review

1/17/2009

Aristocort for Rash

This treatment helps me a lot with my sweating and rashes. I'm really prone to getting pimples on my backside, but this cream takes care of it quickly.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about aristocort

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How long does it take for ARISTOCORT to work?

"This medication contains a topical anti-inflammatory drug from the corticosteroid family. It typically reduces inflammation and itching. Several days of treatment may be required to see the full effect."

Answered by AI

How does ARISTOCORT work in the body?

"Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here.

This medication is used to treat irritated skin, including conditions like psoriasis and eczema. It may also help with itchiness. The medication works by reducing swelling and inflammation of the skin. This medication is available in different forms and brand names. The specific brand may not be available for all the conditions discussed."

Answered by AI

Is ARISTOCORT a hydrocortisone?

"ARISTOCORT is a corticosteroid that comes in the form of a cream or ointment."

Answered by AI

What is ARISTOCORT cream used for?

"This medication is used to reduce the swelling, itching, and redness that can occur in a variety of skin conditions, such as eczema, dermatitis, allergies, and rash. It is a medium- to strong-potency corticosteroid."

Answered by AI

Clinical Trials for Aristocort

Image of Sunnybrook Health Sciences Centre in Toronto, Canada.

Steroids for Rheumatoid Arthritis

18+

All Sexes

Toronto, Canada

People living with rheumatoid arthritis (RA) often experience flares-periods where their symptoms suddenly get worse. These flares can cause significant pain, make it harder to move and do daily activities, and lower overall quality of life. Doctors often treat flares with medications called glucocorticoids (GCs), which reduce inflammation. These medications can be taken by mouth (oral/PO) or given as a single injection into the muscle (intramuscular/IM). However, it's not clear which option works better from the patient's point of view-especially when it comes to relief of symptoms, improvements in function, and satisfaction with treatment. Most research so far has focused on how well the drugs control the disease, rather than how they impact the patient's overall experience. Our Research Questions: 1. Does a single GC injection work just as well as taking pills over a few weeks in improving symptoms reported by patients? 2. How do the two treatments compare in terms of symptom relief, ability to function, and patient satisfaction? 3. What do patients think and feel about using GCs to treat RA flares? What We Think: We believe that a one-time GC injection is just as good as taking pills for a few weeks when it comes to managing RA flares. In fact, the injection might even be safer and preferred by patients. What We're Doing: We will study 220 adults with RA who are currently having a flare (with at least 3 swollen and tender joints). These patients will be recruited from rheumatology clinics at the University of Toronto and must not have used GCs in the past month. They will be randomly assigned to receive either: A single injection (Methylprednisolone 120 mg), or Oral pills (Prednisone starting at 15 mg daily and tapering down over 3 weeks). The main thing we'll look at is how much better patients feel after 6 weeks, based on a questionnaire designed to measure RA flares. We'll also look at how well they function, how satisfied they are with the treatment, and whether they had any side effects. In addition, 20 patients (10 from each group) will be interviewed to understand their experiences and opinions about flare treatment in more detail. Why This Is Possible: We've already surveyed University of Toronto rheumatologists who support the idea and provided input on study design. We've also partnered with experts in research methods, national arthritis organizations, and patient groups to make sure the study is relevant and meaningful. Ethics approval has been obtained. Why It Matters: RA flares can have a major impact on people's lives. While current treatments help control inflammation, we need to better understand how these treatments affect people from their own perspective. This study will shift the focus to what matters most to patients, helping doctors and patients choose the best treatment based not only on medical results but also on the patient's experience. This could lead to more effective and personalized care for people living with RA.

Phase 4

Waitlist Available

Has No Placebo

Sunnybrook Health Sciences Centre (+4 Sites)

Have you considered Aristocort clinical trials? We made a collection of clinical trials featuring Aristocort, we think they might fit your search criteria.

Have you considered Aristocort clinical trials? We made a collection of clinical trials featuring Aristocort, we think they might fit your search criteria.