Your session is about to expire
What is Topicort
DesoximetasoneThe Generic name of this drug
Treatment SummaryGlucocorticoid creams are topical anti-inflammatory medications used to treat skin conditions such as dermatitis, skin allergies, and psoriasis.
Desoximetasoneis the brand name
Topicort Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Desoximetasone
Desoximetasone
1985
66
Effectiveness
How Topicort Affects PatientsDesoximetasone is a type of medication that reduces inflammation, itching, and constricts blood vessels when applied to the skin. It is a powerful drug and should not be used with tightly sealed bandages. It should only be used for two weeks at a time and stopped once the desired results are achieved.
How Topicort works in the bodyTopical steroids reduce inflammation, but how they do this is not known for sure. It's thought that they work by changing the way cells make certain molecules that cause inflammation. Steroids bind to receptors in cells and then move inside the cell and bind to DNA, which causes certain genes to be activated or turned off. This then changes the way cells make molecules like prostaglandins and leukotrienes, which are linked to inflammation. The process is thought to start with the drug blocking the release of arachidonic acid from cell membranes, which is needed to make these molecules.
When to interrupt dosage
The suggested dosage of Topicort is contingent upon the specified condition, for instance Atopic Dermatitis, corticosteroid-responsive dermatoses and Psoriasis. The measure can be found in the table below, contingent upon the technique of delivery (e.g. Topical or Cream - Topical).Condition
Dosage
Administration
Psoriasis Vulgaris
0.0025 mg/mg, , 0.0005 mg/mg, 2.5 mg/mL, 0.05 %, 0.25 %
, Topical, Ointment, Ointment - Topical, Cream, Cream - Topical, Gel, Gel - Topical, Spray, Spray - Topical, Emulsion - Topical, Emulsion
Psoriasis
0.0025 mg/mg, , 0.0005 mg/mg, 2.5 mg/mL, 0.05 %, 0.25 %
, Topical, Ointment, Ointment - Topical, Cream, Cream - Topical, Gel, Gel - Topical, Spray, Spray - Topical, Emulsion - Topical, Emulsion
corticosteroid-responsive dermatoses
0.0025 mg/mg, , 0.0005 mg/mg, 2.5 mg/mL, 0.05 %, 0.25 %
, Topical, Ointment, Ointment - Topical, Cream, Cream - Topical, Gel, Gel - Topical, Spray, Spray - Topical, Emulsion - Topical, Emulsion
Allergic Contact Dermatitis
0.0025 mg/mg, , 0.0005 mg/mg, 2.5 mg/mL, 0.05 %, 0.25 %
, Topical, Ointment, Ointment - Topical, Cream, Cream - Topical, Gel, Gel - Topical, Spray, Spray - Topical, Emulsion - Topical, Emulsion
Warnings
There are 20 known major drug interactions with Topicort.Common Topicort Drug Interactions
Drug Name
Risk Level
Description
2-Methoxyethanol
Major
The risk or severity of adverse effects can be increased when Desoximetasone is combined with 2-Methoxyethanol.
9-(N-methyl-L-isoleucine)-cyclosporin A
Major
The risk or severity of adverse effects can be increased when Desoximetasone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Abatacept
Major
The risk or severity of adverse effects can be increased when Desoximetasone is combined with Abatacept.
Abetimus
Major
The risk or severity of adverse effects can be increased when Desoximetasone is combined with Abetimus.
Acteoside
Major
The risk or severity of adverse effects can be increased when Desoximetasone is combined with Acteoside.
Topicort Toxicity & Overdose RiskApplying desoximetasone to the skin may lead to an overdose which can cause thinning of the skin and a weakened ability of the adrenal gland to respond to stress.
Topicort Novel Uses: Which Conditions Have a Clinical Trial Featuring Topicort?
88 active trials are currently examining the potential of Topicort to address Psoriasis, Atopic Dermatitis and Plaque Psoriasis.Condition
Clinical Trials
Trial Phases
Allergic Contact Dermatitis
2 Actively Recruiting
Phase 2, Phase 3, Not Applicable
corticosteroid-responsive dermatoses
0 Actively Recruiting
Psoriasis
0 Actively Recruiting
Psoriasis Vulgaris
22 Actively Recruiting
Early Phase 1, Phase 4, Phase 3, Not Applicable, Phase 2
Topicort Reviews: What are patients saying about Topicort?
5Patient Review
4/26/2012 I've been using this medication for a while now, but my recent responsibilities as a caregiver have exacerbated my condition. Thankfully, Topicort was able to quickly clear up my skin in just three days. It's dry, so I just use a thin layer of Vaseline to keep it moistened.
5Patient Review
10/18/2008 I've had psoriasis for most of my life, and Topicort is the only thing that has ever worked well for me. Within two days, my skin was 90% better...and with consistent use, it should stay that way.
5Patient Review
3/9/2010 I had a great experience with this treatment. It cleared up my lichen planis quickly and I haven't had any problems since.
5Patient Review
7/8/2010 This was the only medicated cream that quickly and effectively cleared up my rash. I've tried other creams before, but they only made the rash worse and it would spread more quickly. If you're dealing with a similar issue, I highly recommend this cream.
5Patient Review
5/28/2011 I was really amazed at how quickly this treatment worked. My skin condition disappeared within just two days!
5Patient Review
6/2/2020 This medication always gets rid of my psoriasis for a good length of time. I highly recommend it!
4.7Patient Review
12/20/2009 The cream has effectively treated the redness and scaling on my leg, though I'm not sure what the exact diagnosis is. I've only been using it for a short time so I can't speak to long-term results yet.
4.7Patient Review
3/27/2014 I developed a rash for no apparent reason and tried several over-the-counter creams to no avail. Finally, I went to the dermatologist who prescribed this medication. It cleared up the rash within just a couple of days - super easy and effective.
4.7Patient Review
1/2/2013 This treatment quickly got rid of my itchiness and redness. I only had to use it once or twice a day for about a week, which was really convenient.
4Patient Review
5/18/2008 I had a problem with dry, bumpy acne on my chin. I used this treatment once a day for two weeks and it cleared the problem right up.
3.7Patient Review
7/28/2008 Itching and swelling were both much better within 24 hours. I had a bad case of heat rash, but this treatment really helped.
3.3Patient Review
7/26/2009 I am currently using this product to treat poison ivy, and I was wondering if it would be okay to wear a long sleeve shirt over the treatment.
2.7Patient Review
3/5/2009 I went back to the dermatologist after a spot developed on my hand. They zapped it with liquid nitrogen, but now it's worse...
2.3Patient Review
4/18/2014 The price is way too expensive for the amount you get.
Patient Q&A Section about topicort
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How long does it take Topicort to work?
"This medication contains a topical anti-inflammatory drug from the cortisone family (corticosteroid). Typically, it is used to treat inflammation and itching. It requires several days for the medication to take effect."
Answered by AI
What are the side effects of desoximetasone?
"The following are symptoms of a reaction to a medication: burning, itching, irritation, redness, or dryness of the skin; tiny red bumps or rash around the mouth; unwanted hair growth; acne; small white or red bumps on the skin; bruising or shiny skin; red or purple blotches or lines under the skin; thin, fragile, or dry skin."
Answered by AI
Is Topicort ointment a steroid?
"Desoximetasone is a steroid medication that is applied to the skin to treat conditions like inflammation and plaque psoriasis."
Answered by AI
What is Topicort used to treat?
"This medication is used to treat conditions such as eczema, dermatitis, allergies, and rash by reducing swelling, itching, and redness. It is a strong corticosteroid."
Answered by AI