This trial is evaluating whether Cannabidiol (CBD) will improve 2 primary outcomes and 4 secondary outcomes in patients with Arthrosis. Measurement will happen over the course of Up to Week 60.
This trial requires 100 total participants across 2 different treatment groups
This trial involves 2 different treatments. Cannabidiol (CBD) is the primary treatment being studied. Participants will all receive the same treatment. Some patients will receive a placebo treatment. The treatments being tested are in Phase 2 & 3 and have had some early promising results.
"Based on the study by Zou, et al, we can only explain one reason for degenerative joint diseases. The change and loss of cartilage cells can occur as well as the increase of osteoclasts which causes aseptic cartilage degeneration in articular joints." - Anonymous Online Contributor
"There are many different treatments for arthrosis, some of which have been previously tested. If you are not satisfied with the treatment your doctor can offer, you can speak to a professional consultant who specialises in joint disorders to help you make the best choice for yourself." - Anonymous Online Contributor
"Arthrosis affects up to 8% of the adult general population and accounts for a large proportion of work absenteeism in primary care settings. It is a medical condition of considerable complexity that has multiple etiologies, many sub-types and a plethora of management options." - Anonymous Online Contributor
"Even in patients with severe arthrosis associated with large joint effusion, arthroscopy with debridement of the synovial membrane is successful in 74% of the cases. Synovectomy is usually successful because the arthrosis persists in the residual joint. For patients with arthrosis due to rheumatoid arthritis, synovectomy is ineffective. Although synovectomy has been done lately with improved surgical technique, it is still recommended only for those patients with poor functional status, those with refractory arthrosis, and for those patients who are unresponsive to conservative surgery." - Anonymous Online Contributor
"Arthrosis is a form of degenerative disease of cartilage which is seen most commonly in the knee, and the hip.\nThe signs of knee arthrosis involve swelling, pain and reduced range of motion. The signs of hip arthrosis include frequent, painful and bloody urination, or an inconsistent stream during urination. Sudden onset of erectile disfunction is also a sign of hip arthrosis." - Anonymous Online Contributor
"Fewer than 2 (1.4%) reported arthrosis a year for all age groups. Women (0.4%) had a significantly lower age-group rate of arthrosis than did men (0.8%). There was no significant age difference between women and men. The only age group with a significant difference in men versus women was 65 and more years of age." - Anonymous Online Contributor
"A new compound being developed for the medical use in people with multiple sclerosis is cannabidiol. It is still in phase II trials and it will be a matter of time when its safety and efficacy in patients shall be proven." - Anonymous Online Contributor
"Many conditions present similar clinical features of arthrosis, but they have different etiologies of arthritis. The diagnosis of arthrosis should be based on the clinical picture, the causative condition, and specific treatment for each cause of arthrosis." - Anonymous Online Contributor
"The use of CBD has not been established as a therapy for RA. CBD has not shown significant effects on joint symptoms or function in patients with knee arthritis. Patients who are using CBD for their joint pain may experience nausea, dizziness, and sleepiness; these effects may be dose dependent, so CBD is not recommended for those who require high doses for alleviating certain specific symptoms." - Anonymous Online Contributor
"Findings from a recent study represents the largest experience of people with rheumatic conditions using CBD for knee and hip pain. Most adverse events were mild to moderate and not serious. There were no apparent adverse effects on coagulation. Findings from a recent study demonstrates that CBD is not generally unsafe for people with rheumatic conditions." - Anonymous Online Contributor
"The current literature on cannabis as a therapeutic agent is limited. The first CBD-based drug for therapeutic use seems to have been developed in Canada and is used for treatment-refractory, moderate and severe spasticity. There is a significant need for clinical studies on the therapeutic potential of CBD for a broad range of disorders." - Anonymous Online Contributor
"Despite the large amount of information, it has been difficult to compare the findings of the different studies. The lack of a consensus definition for arthrosis, a group-based comparison, and the use of varying designs may all bias results. Because evidence is difficult to compare, the future of arthrosis treatment may be to use the 'best available evidence' with new strategies of treatment." - Anonymous Online Contributor