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What is Eliquis
ApixabanThe Generic name of this drug
Treatment SummaryApixaban is an oral medication used to prevent and treat blood clots. It works by targeting a protein called Factor Xa which plays a role in blood clotting. Apixaban is sold under the brand name Eliquis and was approved by the FDA in 2012.
Eliquisis the brand name
Eliquis Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Eliquis
Apixaban
2012
15
Approved as Treatment by the FDA
Apixaban, otherwise known as Eliquis, is approved by the FDA for 11 uses which include Disease and recurrent Prophylaxis of Deep Vein Thrombosis .Disease
recurrent Prophylaxis of Deep Vein Thrombosis
Arthroplasty
Pulmonary Embolism
Atrial Fibrillation
Total Knee Arthroplasty
Systemic Embolism
Deep Vein Thrombosis
Pulmonary Embolism
Stroke
Deep Vein Thrombosis
Effectiveness
How Eliquis Affects PatientsApixaban works by blocking the clotting proteins factor Xa and prothrominase, preventing them from forming blood clots.
How Eliquis works in the bodyApixaban stops the formation of blood clots by inhibiting the activity of a certain type of blood protein called factor Xa. It also blocks prothrominase, which helps to prevent the formation of a clot.
When to interrupt dosage
The proposed dosage of Eliquis is contingent upon the indicated condition, including Deep Vein Thrombosis (DVT), Deep Vein Thrombosis and Arthroplasty. The amount of dosage varies, depending on the technique of delivery (e.g. Oral or Tablet, film coated - Oral) featured in the table beneath.Condition
Dosage
Administration
Total Knee Arthroplasty
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
recurrent Prophylaxis of Deep Vein Thrombosis
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
Disease
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
Deep Vein Thrombosis
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
Atrial Fibrillation
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
Stroke
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
Arthroplasty
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
Deep Vein Thrombosis
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
Pulmonary Embolism
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
Pulmonary Embolism
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
Systemic Embolism
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
Warnings
Eliquis ContraindicationsCondition
Risk Level
Notes
Hemorrhage
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Apixaban may interact with Pulse Frequency
Common Eliquis Drug Interactions
Drug Name
Risk Level
Description
(R)-warfarin
Major
Apixaban may increase the anticoagulant activities of (R)-warfarin.
(S)-Warfarin
Major
Apixaban may increase the anticoagulant activities of (S)-Warfarin.
4-hydroxycoumarin
Major
Apixaban may increase the anticoagulant activities of 4-hydroxycoumarin.
Abciximab
Major
Apixaban may increase the anticoagulant activities of Abciximab.
Acenocoumarol
Major
Apixaban may increase the anticoagulant activities of Acenocoumarol.
Eliquis Toxicity & Overdose RiskAnimal studies suggest that apixaban may increase a mother's risk of bleeding during pregnancy, but it is unknown if this is true for humans. Therefore, apixaban should only be used if the benefits outweigh the risks. It is not known if apixaban is safe and effective during labor and delivery, but animal studies suggest an increased rate of maternal bleeding. It is not known if apixaban is excreted in human milk, but animal studies have shown that it is excreted in rat milk. Nursing mothers should discuss the risks and benefits of either stopping breastfeeding or taking apixaban. Apixaban has not been
Eliquis Novel Uses: Which Conditions Have a Clinical Trial Featuring Eliquis?
83 active trials are presently being conducted to assess the potential of Eliquis for alleviating Deep Vein Thrombosis (DVT), Stroke and Pulmonary Embolism.Condition
Clinical Trials
Trial Phases
Deep Vein Thrombosis
0 Actively Recruiting
Atrial Fibrillation
4 Actively Recruiting
Not Applicable
Total Knee Arthroplasty
15 Actively Recruiting
Phase 3, Not Applicable, Phase 2, Phase 4
Pulmonary Embolism
0 Actively Recruiting
Arthroplasty
10 Actively Recruiting
Not Applicable, Phase 4, Phase 2
recurrent Prophylaxis of Deep Vein Thrombosis
0 Actively Recruiting
Systemic Embolism
2 Actively Recruiting
Not Applicable
Disease
0 Actively Recruiting
Deep Vein Thrombosis
17 Actively Recruiting
Phase 4, Phase 3, Not Applicable, Phase 1, Phase 2
Pulmonary Embolism
35 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Early Phase 1, Phase 1, Phase 2
Stroke
11 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Eliquis Reviews: What are patients saying about Eliquis?
5Patient Review
7/25/2022 I haven't experienced any negative side effects and I really feel like it's kept me alive. The only downside is that it's quite expensive.
4Patient Review
1/3/2022 I'm a 47-year-old firefighter who has a history of atrial fibrillation and deep vein thrombosis. My doctor put me on this medication 3 weeks ago to prevent another clotting episode, and while I have noticed that I'm more tired than usual and having trouble focusing, I would rather deal with these issues than suffer from a stroke or another DVT.
4Patient Review
5/11/2021 I've been on Eliquis for four months to treat a pulmonary embolism. I'm grateful that the medication has helped dissolve the blood clot, but the side effects have been really tough to deal with. Headaches, shortness of breath, chest pain, and joint pain have all made it difficult to get through my day-to-day.
4Patient Review
5/22/2021 I just started this treatment and I haven't experienced any side effects yet. My upset stomach could be from not eating, but I'm on it for DVT so that might also be a factor. I'll give more information if anything else comes up.
4Patient Review
10/7/2022 I've been on this medication for a few years now due to congestive heart failure and several blockages. Recently, I also started having problems with bladder bleeding, as well as on my arms and legs. I've decided to stop taking the medication and take my chances; it's my choice and my life.
3.7Patient Review
5/4/2021 It's alright.
3Patient Review
1/9/2022 I'm a 58 year old male who's been taking Apixaban for two months now. I haven't noticed any side effects, but I have noticed that when I do get cuts, they don't seem to bleed as much. I'll have to mention this to my doctor next time I see him.
2.7Patient Review
6/29/2022 I'm a recent user so I can't speak to its long-term effectiveness yet. So far, however, I've had some difficulty with word-finding and increased fatigue. Additionally, I began feeling dizzy a few days ago which is concerning. Overall, though, it hasn't been too bad and I'll be discussing these effects with my primary care physician tomorrow and cardiologist next week.
2.7Patient Review
5/7/2022 Unfortunately, there are too many side effects that come with this treatment. For example, I can't walk more than 15 feet without feeling dizzy and needing to sit down. Additionally, my legs and arms feel weak and I often felt like I was going to faint.
2.7Patient Review
10/31/2022 Not long after beginning Eliquis, I started experiencing nausea. My doctors did an ablation and prescribed a new blood pressure medication; however, the side effects of the new medication were so severe that I stopped taking it within 30 minutes. I have a follow-up appointment soon, but I'm not sure what to do in the meantime.
2.3Patient Review
6/25/2022 I developed an AFib after falling and injuring my knee. This required multiple surgeries, a skin graft, and a lot of physical therapy. The cost was prohibitive (90 days $420) and I could not receive help because I am on Medicare part D.
2.3Patient Review
8/31/2022 Eliquis unfortunately didn't provide the results I needed, so I had to switch back to Warfarin after 10 years.
1.7Patient Review
5/1/2021 My mother was given this medication for Afib. A few weeks after starting the treatment, she had two strokes in quick succession. These left her bedridden and on hospice care. She also experienced bleeds from her eyes while taking this medication. I would not recommend it to anyone with Afib.
1Patient Review
6/30/2022 My husband was prescribed this after being diagnosed with AFib around November 2020. He had a stroke at work on 6/6/22 and died 6/10/22.
1Patient Review
9/12/2021 I think this medication is dangerous and should be taken off the market. I had no strength and all I could do was sleep. I also had hives, my lips swelled up so bad that I couldn't eat, and a minor cut on my finger took three days to stop bleeding.
Patient Q&A Section about eliquis
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What foods should I avoid while taking Eliquis?
"Limit caffeine intake as it can indirectly promote fatty plaques in your blood vessels and increase the risk of heart disease and stroke."
Answered by AI
Is Eliquis a blood thinner or anticoagulant?
"Eliquis is FDA-approved to help prevent and treat certain types of dangerous blood clotting that can block blood vessels throughout your body. Eliquis is an anticoagulant drug, which means it is designed to thin your blood and make it less likely to form clots."
Answered by AI
What are the side effects of taking Eliquis?
"Symptoms of severe internal bleeding may include:
-bleeding from cuts that take longer to stop than usual -bleeding from the nose or gums -dizziness -easy bruising -excessively heavy menstrual bleeding -minor bleeding -nausea"
Answered by AI
What is a Eliquis used for?
"This can lead to blood clots, stroke, heart attack, and other heart problems.
Generic Name: apixaban
Apixaban is used to prevent serious blood clots from forming due to a certain irregular heartbeat (atrial fibrillation) or after hip/knee replacement surgery. With atrial fibrillation, part of the heart does not beat the way it should. This can lead to blood clots, stroke, heart attack, and other heart problems."
Answered by AI