Eliquis

Deep Vein Thrombosis, Arthroplasty, Pulmonary Embolism + 8 more
Treatment
16 FDA approvals
20 Active Studies for Eliquis

What is Eliquis

ApixabanThe Generic name of this drug
Treatment SummaryApixaban is an oral medication used to prevent and treat blood clots. It works by targeting a protein called Factor Xa which plays a role in blood clotting. Apixaban is sold under the brand name Eliquis and was approved by the FDA in 2012.
Eliquisis the brand name
image of different drug pills on a surface
Eliquis Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Eliquis
Apixaban
2012
15

Approved as Treatment by the FDA

Apixaban, otherwise known as Eliquis, is approved by the FDA for 16 uses which include Non Valvular Atrial Fibrillation (nv AF) and Recurrent Pulmonary Embolism (Disorder) .
Non Valvular Atrial Fibrillation (nv AF)
Recurrent Pulmonary Embolism (Disorder)
Deep Vein Thrombosis
Prophylaxis of Deep Vein Thrombosis
Deep vein thrombosis recurrent
Arthroplasty
recurrent Prophylaxis of Deep Vein Thrombosis
Deep Vein Thrombosis
Total Knee Arthroplasty
Stroke
Atrial Fibrillation
Systemic Embolism
Pulmonary Embolism
Disease
Pulmonary Embolism
Deep Vein Thrombosis

Effectiveness

How Eliquis Affects PatientsApixaban works by blocking the clotting proteins factor Xa and prothrominase, preventing them from forming blood clots.
How Eliquis works in the bodyApixaban stops the formation of blood clots by inhibiting the activity of a certain type of blood protein called factor Xa. It also blocks prothrominase, which helps to prevent the formation of a clot.

When to interrupt dosage

The proposed dosage of Eliquis is contingent upon the indicated condition, including Deep Vein Thrombosis (DVT), Deep Vein Thrombosis and Arthroplasty. The amount of dosage varies, depending on the technique of delivery (e.g. Oral or Tablet, film coated - Oral) featured in the table beneath.
Condition
Dosage
Administration
Deep Vein Thrombosis
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
Pulmonary Embolism
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
Atrial Fibrillation
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
Disease
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
Deep Vein Thrombosis
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
Stroke
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
recurrent Prophylaxis of Deep Vein Thrombosis
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
Total Knee Arthroplasty
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
Systemic Embolism
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
Arthroplasty
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral
Pulmonary Embolism
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral

Warnings

Eliquis Contraindications
Condition
Risk Level
Notes
Hemorrhage
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Apixaban may interact with Pulse Frequency
There are 20 known major drug interactions with Eliquis.
Common Eliquis Drug Interactions
Drug Name
Risk Level
Description
(R)-warfarin
Major
Apixaban may increase the anticoagulant activities of (R)-warfarin.
(S)-Warfarin
Major
Apixaban may increase the anticoagulant activities of (S)-Warfarin.
4-hydroxycoumarin
Major
Apixaban may increase the anticoagulant activities of 4-hydroxycoumarin.
Abciximab
Major
Apixaban may increase the anticoagulant activities of Abciximab.
Acenocoumarol
Major
Apixaban may increase the anticoagulant activities of Acenocoumarol.
Eliquis Toxicity & Overdose RiskAnimal studies suggest that apixaban may increase a mother's risk of bleeding during pregnancy, but it is unknown if this is true for humans. Therefore, apixaban should only be used if the benefits outweigh the risks. It is not known if apixaban is safe and effective during labor and delivery, but animal studies suggest an increased rate of maternal bleeding. It is not known if apixaban is excreted in human milk, but animal studies have shown that it is excreted in rat milk. Nursing mothers should discuss the risks and benefits of either stopping breastfeeding or taking apixaban. Apixaban has not been
image of a doctor in a lab doing drug, clinical research

Eliquis Novel Uses: Which Conditions Have a Clinical Trial Featuring Eliquis?

83 active trials are presently being conducted to assess the potential of Eliquis for alleviating Deep Vein Thrombosis (DVT), Stroke and Pulmonary Embolism.
Condition
Clinical Trials
Trial Phases
Pulmonary Embolism
25 Actively Recruiting
Phase 4, Phase 3, Early Phase 1, Not Applicable
Total Knee Arthroplasty
6 Actively Recruiting
Not Applicable, Phase 2, Phase 3, Phase 4
recurrent Prophylaxis of Deep Vein Thrombosis
0 Actively Recruiting
Atrial Fibrillation
4 Actively Recruiting
Not Applicable
Deep Vein Thrombosis
0 Actively Recruiting
Deep Vein Thrombosis
10 Actively Recruiting
Not Applicable, Phase 2, Phase 3, Phase 4
Disease
0 Actively Recruiting
Arthroplasty
3 Actively Recruiting
Not Applicable
Stroke
9 Actively Recruiting
Phase 4, Phase 1, Not Applicable
Pulmonary Embolism
0 Actively Recruiting
Systemic Embolism
3 Actively Recruiting
Not Applicable

Eliquis Reviews: What are patients saying about Eliquis?

5Patient Review
7/25/2022
Eliquis for Treatment to Prevent Blood Clots in Chronic Atrial Fibrillation
I haven't experienced any negative side effects and I really feel like it's kept me alive. The only downside is that it's quite expensive.
4Patient Review
1/3/2022
Eliquis for Deep Vein Thrombosis Prevention
I'm a 47-year-old firefighter who has a history of atrial fibrillation and deep vein thrombosis. My doctor put me on this medication 3 weeks ago to prevent another clotting episode, and while I have noticed that I'm more tired than usual and having trouble focusing, I would rather deal with these issues than suffer from a stroke or another DVT.
4Patient Review
5/11/2021
Eliquis for Blood Clot in Lung
I've been on Eliquis for four months to treat a pulmonary embolism. I'm grateful that the medication has helped dissolve the blood clot, but the side effects have been really tough to deal with. Headaches, shortness of breath, chest pain, and joint pain have all made it difficult to get through my day-to-day.
4Patient Review
5/22/2021
Eliquis for Treatment to Prevent Recurrence of a Clot in a Deep Vein
I just started this treatment and I haven't experienced any side effects yet. My upset stomach could be from not eating, but I'm on it for DVT so that might also be a factor. I'll give more information if anything else comes up.
4Patient Review
10/7/2022
Eliquis for Treatment to Prevent Recurrence of a Clot in a Deep Vein
I've been on this medication for a few years now due to congestive heart failure and several blockages. Recently, I also started having problems with bladder bleeding, as well as on my arms and legs. I've decided to stop taking the medication and take my chances; it's my choice and my life.
View All Reviews
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about eliquis

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What foods should I avoid while taking Eliquis?

"Limit caffeine intake as it can indirectly promote fatty plaques in your blood vessels and increase the risk of heart disease and stroke."

Answered by AI

Is Eliquis a blood thinner or anticoagulant?

"Eliquis is FDA-approved to help prevent and treat certain types of dangerous blood clotting that can block blood vessels throughout your body. Eliquis is an anticoagulant drug, which means it is designed to thin your blood and make it less likely to form clots."

Answered by AI

What is so special about Eliquis?

"Eliquis is a blood thinner that prevents blood clots from forming by stopping the enzyme complex called factor Xa from working. This reduces the risk of having a stroke or heart attack."

Answered by AI

What are the side effects of taking Eliquis?

"Symptoms of severe internal bleeding may include:

-bleeding from cuts that take longer to stop than usual -bleeding from the nose or gums -dizziness -easy bruising -excessively heavy menstrual bleeding -minor bleeding -nausea"

Answered by AI

What is a Eliquis used for?

"This can lead to blood clots, stroke, heart attack, and other heart problems.

Generic Name: apixaban

Apixaban is used to prevent serious blood clots from forming due to a certain irregular heartbeat (atrial fibrillation) or after hip/knee replacement surgery. With atrial fibrillation, part of the heart does not beat the way it should. This can lead to blood clots, stroke, heart attack, and other heart problems."

Answered by AI

Clinical Trials for Eliquis

Have you considered Eliquis clinical trials? We made a collection of clinical trials featuring Eliquis, we think they might fit your search criteria.
Have you considered Eliquis clinical trials? We made a collection of clinical trials featuring Eliquis, we think they might fit your search criteria.
Have you considered Eliquis clinical trials? We made a collection of clinical trials featuring Eliquis, we think they might fit your search criteria.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top