40 Participants Needed

Cognitive-Somatosensory-Motor Training for Stroke

(iCOSMO Trial)

Recruiting at 1 trial location
UG
OY
Overseen ByOlga Yaroslavtseva, BSc
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University Health Network, Toronto
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The iCOSMO study investigates the feasibility and beneficial effects of an intervention combining sensation, motor and cognition to improve arm and hand function after chronic stroke.

Do I have to stop taking my current medications for the trial?

The trial protocol does not specify whether you need to stop taking your current medications.

What safety data exists for Cognitive-Somatosensory-Motor Training for stroke?

The provided research does not directly address safety data for Cognitive-Somatosensory-Motor Training or its variants like iCOSMO. The studies focus on the effectiveness of somatosensory retraining and stimulation in improving motor function after stroke, but they do not specifically mention safety outcomes or adverse effects related to these interventions.12345

Is the treatment Cognitive-Somatosensory-Motor Training for Stroke promising?

Yes, Cognitive-Somatosensory-Motor Training for Stroke is promising because it combines physical and sensory training to improve motor and sensory functions in stroke patients. Studies show that somatosensory stimulation can enhance motor function and help maintain training benefits, making it a valuable tool for stroke rehabilitation.12567

What data supports the idea that Cognitive-Somatosensory-Motor Training for Stroke is an effective treatment?

The available research shows that Cognitive-Somatosensory-Motor Training can improve motor function in stroke patients. For example, one study found that somatosensory stimulation, which is part of this training, led to better hand motor function in patients with chronic strokes. This improvement was greater than in sessions without this stimulation, and the benefits lasted for at least 30 days. This suggests that the treatment can be a helpful tool in stroke rehabilitation, especially for those with certain types of brain injuries.13578

Who Is on the Research Team?

Mark Bayley | UHN Research

Mark Bayley, MD

Principal Investigator

Toronto Rehabilitation Institute

Are You a Good Fit for This Trial?

The iCOSMO trial is for individuals who have had a stroke and are looking to improve the function of their arm and hand. Specific eligibility criteria details were not provided.

Inclusion Criteria

I have weakness or sensory loss in my arms.
I have been diagnosed with a stroke.
It has been over 6 months since my stroke.
See 1 more

Exclusion Criteria

I have had a brain disorder other than a stroke.
I have arm or hand issues not caused by a stroke.
I can follow instructions and provide consent for treatment.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Baseline

Participants are tested at the start and end of the baseline phase

1 week

Treatment

Participants receive the iCOSMO intervention or a home-based exercise programme for 6 weeks

6 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • integrated Somatosensory-MOtor training using a COgnitive approach(iCOSMO)
Trial Overview This study tests two types of training programs: GRASP, which patients do at home, and iCOSMO, which integrates sensory, motor, and cognitive exercises to aid recovery after a chronic stroke.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: iCOSMOExperimental Treatment1 Intervention
Group II: Home GRASPActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University Health Network, Toronto

Lead Sponsor

Trials
1,555
Recruited
526,000+

StrokeCog clinical training platform

Collaborator

Trials
1
Recruited
40+

Published Research Related to This Trial

Cognitive sensory motor training therapy showed promising results in improving upper extremity motor function in seven patients with chronic stroke or traumatic brain injuries, with an average increase of 7.7 points in Action Research Arm (ARA) scores over 2.5 months of training.
All patients demonstrated improvement, suggesting that this therapy could be a valuable rehabilitation method, although further studies with larger sample sizes are needed to confirm its efficacy.
Improved function of hemiplegic upper extremity after cognitive sensory motor training therapy in chronic stroke patients: preliminary report of a case series.Wongphaet, P., Butrach, W., Sangkrai, S., et al.[2007]
The COMPoSE intervention is a novel rehabilitation program designed for stroke patients that integrates both somatosensory and motor training to address upper limb deficits, utilizing a standardized training matrix over 10 sessions in 3 weeks.
This approach includes specific training variables like grasp pressure and object texture, along with feedback mechanisms and high-dose repetitive practice, aiming to enhance skill acquisition and improve functional outcomes in stroke recovery.
COMbined Physical and somatoSEnsory training after stroke: Development and description of a novel intervention to improve upper limb function.Gopaul, U., van Vliet, P., Callister, R., et al.[2019]
Somatosensory retraining programs can significantly improve somatosensory discrimination skills in the arm of stroke survivors, with an average effect size of 0.85 across various modalities, indicating a meaningful impact on sensory recovery.
There is a trend suggesting that these retraining programs may also enhance motor function and arm use, as indicated by narrative analysis of studies involving 89 participants, although more research is needed to confirm these findings.
The effectiveness of somatosensory retraining for improving sensory function in the arm following stroke: a systematic review.Turville, ML., Cahill, LS., Matyas, TA., et al.[2022]

Citations

Improved function of hemiplegic upper extremity after cognitive sensory motor training therapy in chronic stroke patients: preliminary report of a case series. [2007]
COMbined Physical and somatoSEnsory training after stroke: Development and description of a novel intervention to improve upper limb function. [2019]
The effectiveness of somatosensory retraining for improving sensory function in the arm following stroke: a systematic review. [2022]
Effects of somatosensory stimulation on motor function in chronic cortico-subcortical strokes. [2018]
Motor Imagery Training on Muscle Strength and Gait Performance in Ambulant Stroke Subjects-A Randomized Clinical Trial. [2020]
Nerve Stimulation Enhances Task-Oriented Training for Moderate-to-Severe Hemiparesis 3-12 Months After Stroke: A Randomized Trial. [2019]
Translational studies in neurorehabilitation: from bench to bedside. [2019]
The State-of-the-Science on Somatosensory Function and Its Impact on Daily Life in Adults and Older Adults, and Following Stroke: A Scoping Review. [2017]
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