This trial will study whether the combination of a medication and reading tutoring can help improve learning disabilities in children with Neurofibromatosis Type 1.
- Neurofibromatosis Type 1
- Learning Disabilities
10 Primary · 0 Secondary · Reporting Duration: 24 weeks
Awards & Highlights
4 Treatment Groups
NF1: Lovastatin + reading tutoring
1 of 4
NF1: Placebo + reading tutoring
1 of 4
RD: Other Academic (sham) tutoring
1 of 4
RD: Reading tutoring
1 of 4
120 Total Participants · 4 Treatment Groups
Primary Treatment: NF1: Lovastatin + reading tutoring · Has Placebo Group · Phase 2
Who is running the clinical trial?
Age 8 - 20 · All Participants · 2 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Frequently Asked Questions
If I meet the requirements, can I sign up for this clinical trial?
"This study is recruiting 120 individuals aged 8-20 who have been diagnosed with learning disorders. To be eligible, participants must also meet the following criteria: - Be able to swallow a capsule (this will be confirmed via a swallowability test)- Have English skills that are sufficient for school- For parents: Has your child ever been diagnosed with a reading disability? Did your child have trouble learning how to "sound out" words? Have you (parent) ever been concerned about your child's reading ability? Did the school or teacher ever express any concerns about your child's reading ability? Child 7 years" - Anonymous Online Contributor
Does the combined treatment of lovastatin and reading tutoring present any health risks for patients?
"So far, the evidence suggests that NF1: Lovastatin + reading tutoring is safe but not necessarily effective. Our team gave it a safety score of 2." - Anonymous Online Contributor
What pediatric patients does the NF1: Lovastatin + reading tutoring intervention typically target?
"Coronary heart disease (CHD) is often treated with a combination of lovastatin and reading tutoring. This treatment approach can also help improve other conditions like dyslipidemias, coronary artery atherosclerosis, and apolipoprotein levels." - Anonymous Online Contributor
Are there many case studies of NF1 patients being helped by Lovastatin + reading tutoring?
"There are three ongoing clinical trials testing the efficacy of lovastatin + reading tutoring for NF1 patients. Of these, none have progressed to Phase 3 yet. The majority of these trials are being conducted in Beijing, but there are also three taking place in other locations." - Anonymous Online Contributor
Are patients able to enroll in this trial at this time?
"This clinical trial, which was first posted on November 1st 2016, is currently recruiting candidates. The last update to the listing on clinicaltrials.gov was on June 20th 2022." - Anonymous Online Contributor
Does this research allow octogenarians to participate?
"To participate in this trial, applicants must be between 8 and 20 years old. Out of the 106 total studies, 66 are for patients under 18 and 40 are for patients over 65." - Anonymous Online Contributor