Ecoza

Tinea Pedis, Inflammation, Fungal eye infections + 17 more
Treatment
20 Active Studies for Ecoza

What is Ecoza

EconazoleThe Generic name of this drug
Treatment SummaryGriseofulvin is a broad-spectrum antifungal medication used to treat fungal skin infections. It can be taken orally or given by injection, and is also available as a topical cream. Griseofulvin is also effective against some types of bacteria.
Spectazoleis the brand name
Ecoza Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Spectazole
Econazole
1982
30

Effectiveness

How Ecoza Affects PatientsEconazole is a medication used to treat fungal infections. It works by keeping fungi from getting the nutrients they need to survive and grow. It will not work for infections caused by bacteria or viruses.
How Ecoza works in the bodyEconazole stops fungi from forming a healthy cell membrane. It does this by preventing the production of a certain compound, called ergosterol, from occurring. Without ergosterol, the cell membrane becomes permeable, meaning that its contents leak out. Econazole may also work in other ways, such as inhibiting respiration, blocking certain molecules from entering the cell, and stopping the transformation of yeast into a different form.

When to interrupt dosage

The amount of Ecoza is subordinate to the diagnosed condition, including Cellulitis, Tinea cruris and Fungal eye infections. The measure of dosage is contingent upon the method of delivery (e.g. Cream - Topical or Topical) featured in the underneath table.
Condition
Dosage
Administration
Ringworm
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal
Fungal eye infections
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal
Atopic Dermatitis
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal
Intertrigo
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal
Skin
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal
Balanitis candida
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal
cutaneous candidiasis
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal
Tinea Pedis
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal
Tinea Pedis
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal
severe local inflammatory reactions
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal
Eczema
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal
Tinea Versicolor
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal
Inflammation
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal
cutaneous dermatophyte infection
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal
Skin candida
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal
Cellulitis
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal
Shingles
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal
Tinea Cruris
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal
Tinea
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal
Mycoses
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository - Vaginal, Suppository, Aerosol, foam, Aerosol, foam - Topical, Solution - Topical, Solution, Kit - Topical, Kit, Cream - Vaginal

Warnings

There are 20 known major drug interactions with Ecoza.
Common Ecoza Drug Interactions
Drug Name
Risk Level
Description
Alfuzosin
Major
The metabolism of Alfuzosin can be decreased when combined with Econazole.
Avanafil
Major
The metabolism of Avanafil can be decreased when combined with Econazole.
Bromocriptine
Major
The serum concentration of Bromocriptine can be increased when it is combined with Econazole.
Cabergoline
Major
The serum concentration of Cabergoline can be increased when it is combined with Econazole.
Cariprazine
Major
The metabolism of Cariprazine can be decreased when combined with Econazole.
Ecoza Toxicity & Overdose RiskNo cases of human overdose on econazole have been reported yet. In animal studies, the lowest dose of econazole that was toxic to mice, rats, guinea pigs and dogs was 462, 668, 272 and 160 mg/kg respectively.

Ecoza Novel Uses: Which Conditions Have a Clinical Trial Featuring Ecoza?

303 active studies are currently examining the possible benefits of Ecoza in the management of Atopic Dermatitis, Eczema and Cellulitis.
Condition
Clinical Trials
Trial Phases
Cellulitis
0 Actively Recruiting
Tinea Versicolor
0 Actively Recruiting
Tinea
0 Actively Recruiting
Inflammation
57 Actively Recruiting
Not Applicable, Early Phase 1, Phase 1, Phase 2, Phase 3, Phase 4
Skin candida
0 Actively Recruiting
Fungal eye infections
0 Actively Recruiting
Tinea Pedis
0 Actively Recruiting
Intertrigo
0 Actively Recruiting
Atopic Dermatitis
10 Actively Recruiting
Phase 2, Phase 3, Phase 4
Eczema
0 Actively Recruiting
Ringworm
0 Actively Recruiting
Balanitis candida
0 Actively Recruiting
Tinea Pedis
0 Actively Recruiting
cutaneous candidiasis
0 Actively Recruiting
Skin
0 Actively Recruiting
Mycoses
0 Actively Recruiting
Tinea Cruris
0 Actively Recruiting
severe local inflammatory reactions
0 Actively Recruiting
Shingles
4 Actively Recruiting
Phase 2, Phase 1
cutaneous dermatophyte infection
0 Actively Recruiting

Patient Q&A Section about ecoza

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is econazole used for jock itch?

"Econazole is used to treat skin infections such as athlete's foot, jock itch, and ringworm. This medication can also be used for other purposes as prescribed by a doctor."

Answered by AI

Can I use econazole on my face?

"This medicine is for use on the skin only. Do not use it on your eyes, nose, mouth, or vagina. Wash your hands before and after using this medicine."

Answered by AI

What is Ecoza used for?

"Ecoza is a medicine that is used to treat the symptoms of skin fungal infections, candidiasis, and athlete's foot."

Answered by AI

How long does it take for econazole to work?

"In most cases, people notice an improvement in their symptoms after using econazole cream for a week or two. However, it is important to use the cream for the recommended amount of time, even if symptoms have improved, in order to prevent the condition from returning. For most conditions, econazole cream should be used for 2 weeks, while for athlete's foot, it should be used for 1 month."

Answered by AI

Clinical Trials for Ecoza

Image of UConn Health in Farmington, United States.

Cognitive Remediation for Memory and Thinking Difficulties

18+
All Sexes
Farmington, CT
The goal of this clinical trial is to determine if a neuroscience-based computerized cognitive remediation ("brain training") program can treat neurocognitive dysfunction (i.e., memory or thinking difficulties) that emerges in some older adults following a viral infection. The main questions it aims to answer are: * Does computerized cognitive remediation improve cognitive performance and day-to-day functioning in older adults with postviral neurocognitive dysfunction? * Will treatment effects be maintained over time, leading to better long term cognitive outcomes? * Does the treatment lead to reductions in blood-based markers of inflammation as a potential mechanism of cognitive symptom improvement? * Can the treatment be optimized and refined based on feedback from participants to improve user (patient) experience? Researchers will compare the computerized cognitive remediation program to an active computer-based control condition (alternative computer activities) to see if the computerized cognitive remediation program works to treat postviral neurocognitive dysfunction. Participation takes approximately 43-48 hours over 7 months, with most activities (40-46 hours) completed within the first 7-8 weeks, including: * Initial intake visit: Eligibility confirmation (\~2-3 hours) * Computer activities: About 5 hours per week for \~6 weeks (total \~30 hours) completed on a computer tablet provided by the study and loaned to participants for use during the treatment phase * Weekly remote check-in meetings: \~30 minutes each during treatment * Blood draws: Two sessions (before and after treatment), \~20-30 minutes each * Three research visits: Pre-treatment, post-treatment, and 6-month follow-up (\~2-3 hours each, including assessments of cognitive, emotional, and daily functioning)
Waitlist Available
Has No Placebo
UConn HealthCutter Lindbergh, Ph.D.
Image of Department of Nutritional Sciences in Storrs, United States.

Freeze-dried Grape Powder for Healthy Aging

50 - 75
All Sexes
Storrs, CT
The purpose of this study is to investigate the effects of consuming grape powder on immune profiles in healthy middle- and older-aged individuals. Specifically, the investigators are interested in evaluating the potential effects of grapes in influencing markers of immune function, inflammation, and metabolism that are known to change with aging. Grapes contain several nutrients and antioxidant polyphenols such as resveratrol, quercetin, vitamin K and fiber, which are known to promote heart and immune health. However, the effects of grapes on altering immune profiles within the context of aging is not well understood. Therefore, this study will explore how daily grape consumption impacts certain markers of immunity in healthy middle- and older-aged adults. The main study procedures include consumption of a freeze-dried grape powder and control powder (which tastes the same but has none of the grape compounds that are being studied) mixed with water as a beverage on a daily basis for 4 weeks each. The investigators will additionally ask that participants avoid eating grapes and certain other antioxidant/grape-related foods and beverages throughout the 13-week study. Participants will additionally be asked to complete surveys about their diet, physical activity, and medical history, as well as provide blood samples and body weight measures throughout the course of the study. Participation in the study is expected to last about 6.25 hours over the course of 13 weeks and will include 7 visits.
Recruiting
Paid Trial
Department of Nutritional Sciences
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Image of Abcentra Investigational Site in Los Angeles, United States.

Orticumab for Heart Attack

18+
All Sexes
Los Angeles, CA
The goal of this clinical trial is to determine the clinical effect of orticumab treatment on inflammation in study participants with prior myocardial infarction who have elevated coronary inflammation based on CCTA. The main question it aims to answer is: Clinical effects of orticumab treatment on inflammation of the coronary artery parameters measured with CCTA Researchers will compare the effects with placebo group after 6 months of treatment Participants will Keep the planned study visit appointments Provide complete information about medical and medical history Speak to the study doctor before changing any of non-study treatments, including starting new medications, receiving any vaccinations, or setting out to join any other clinical studies
Phase 2
Recruiting
Abcentra Investigational Site (+6 Sites)Abcentra
Image of School of Public Health in Bloomington, United States.

High Salt Intake for High Blood Pressure

60 - 85
All Sexes
Bloomington, IN
Most Americans consume excess dietary salt based on the recommendations set by the American Heart Association and Dietary Guidelines for Americans. High dietary salt impairs blood pressure control by affecting systemic blood vessels and the kidneys. These changes contribute to excess salt consumption being associated with increased risk for chronic kidney disease and cardiovascular disease, the leading cause of death in America. Salt is particularly deleterious in older adults who are more likely to exhibit salt-sensitive hypertension. However, salt consumption remains high in the United States. Thus, there is a critical need for strategies to counteract the effects of high dietary salt as consumption is likely not going to decrease. One promising option is ketones, metabolites that are produced in the liver during prolonged exercise and very low-calorie diets. While exercise and low-calorie diets are beneficial, not many people engage in these activities. Limited evidence indicates that ketone supplements improve cardiovascular health in humans. Additionally, published rodent data indicates that ketone supplements prevent high salt-induced increases in blood pressure, blood vessel dysfunction, and kidney injury. Our human pilot data also indicates that high dietary salt reduces intrinsic ketone production, but it is unclear whether ketone supplementation confers humans' protection against high salt similar to rodents. Therefore, the investigators seek to conduct a short-term high-dietary salt study to determine whether ketone supplementation prevents high dietary salt from eliciting increased blood pressure, blood vessel dysfunction, and kidney injury/impaired blood flow. The investigators will also measure inflammatory markers in blood samples and isolate immune cells that control inflammation. Lastly, the investigators will also measure blood ketone concentration and other circulating metabolites that may be altered by high salt, which could facilitate novel therapeutic targets to combat high salt.
Recruiting
Has No Placebo
School of Public Health
Image of Tesla MedBed at Tampa-FL in Tampa, United States.

Biophoton Therapy for Stem Cell Proliferation

18 - 70
All Sexes
Tampa, FL
Study Objective The purpose of this clinical study is to evaluate if biophoton therapy, delivered by Tesla BioHealing® Biophoton Generators (Biophotonizer), can increase self-grown stem cells naturally. Study Design This is a randomized, double-blinded, placebo-controlled intervention clinical study to assess the effectiveness of biophoton therapy in impacting stem cells. Approximately 46 volunteers who want to increase self-grown stem cells will participate in the study. Study Randomization The biostatistician will prepare a randomization schedule including a serial of subject numbers. A subject number will be randomly assigned to each study participant, which will assign them to either the control group or the treatment group. Other than the Informed Consent Form (ICF), all study information will be recorded by using the subject number. The Principal Investigator, study physicians, study nurse, data-entry specialists, and biostatisticians, as well as the participants, will be blinded about who received which product during the first two weeks of study participation.
Recruiting
Online Trial
Tesla MedBed at Tampa-FL (+1 Sites)James Z Liu, MD, PhD
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Image of Goldring Center for High Performance Sport in Toronto, Canada.

Physical Activity for Delayed Onset Muscle Soreness

18 - 35
All Sexes
Toronto, Canada
After completing novel activity or exercise we may experience exercise-induced muscle damage (EIMD), resulting in a period of reduced muscle function and delayed onset muscle soreness (DOMS). DOMS is characterized by muscle pain and tenderness that typically resolves within a week. While the precise cause of DOMS is unknown, there is growing evidence implicating damage to the connective tissue that surrounds our muscle fibers and is related to a small amount of inflammation. This inflammation is a normal part of our body's ability to recovery from injuries and may be visualized through the use of ultrasound technology. A variety of recovery techniques have been proposed that may help with the recovery of DOMS such as massage and electrical muscle stimulation, but these are not always accessible. Therefore, we are interested in investigating whether the number of daily steps can affect how you experience DOMS.
Waitlist Available
Has No Placebo
Goldring Center for High Performance Sport
Image of UCSF in San Francisco, United States.

Moisturizers for Aging

65+
All Sexes
San Francisco, CA
This is a randomized, investigator-blinded, self-controlled pilot study of the physiologic response to topical moisturizers among older adults with dry skin. The overarching hypothesis is that skin barrier decline is an important source of chronic inflammation, and that skin barrier restoration with moisturizers can reduce serum biomarkers of inflammation. The primary objective is to determine the feasibility for a larger trial, and the secondary objectives are to determine the extent to which measures of serum inflammation, skin barrier function, and the skin microbiome change in response to moisturizers. Participants will be asked to apply one of two topical moisturizers that are widely available over the counter in the US (Vaseline® 100% pure petroleum jelly or CeraVe® moisturizing cream) once daily for 4 weeks to the front of the torso, buttocks, arms, and legs. Subjects will act as their own control (i.e. they will be asked to apply the study moisturizer they are randomized to for one intervention period (4 weeks) and not to apply topical moisturizers for the other 4- week intervention period). Participants will be randomized in a 1:1:1:1 ratio to one of 4 treatment groups: i. no intervention then CeraVe; ii. CeraVe then no intervention; iii. no intervention then Vaseline; iv. Vaseline then no intervention. At each visit (baseline, week 4, and week 8), participants will undergo skin barrier testing, skin microbiome sampling, and phlebotomy to measure serum inflammatory markers.
Phase 4
Recruiting
UCSFKatrina Abuabara, MD
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