Spectazole

Tinea Pedis, Inflammation, Fungal eye infections + 17 more
Treatment
20 Active Studies for Spectazole

What is Spectazole

EconazoleThe Generic name of this drug
Treatment SummaryA broad-spectrum antifungal medication with some effectiveness against certain types of bacteria. This drug can be used on the skin, orally, or injected to treat fungal infections.
Spectazoleis the brand name
image of different drug pills on a surface
Spectazole Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Spectazole
Econazole
1982
30

Effectiveness

How Spectazole Affects PatientsEconazole is an antifungal medication used to treat fungal infections. It works by stopping fungi from producing substances that are necessary for them to survive. This medication will not work on infections caused by bacteria or viruses.
How Spectazole works in the bodyEconazole works by blocking the enzyme that is needed to make a key component of fungal cell membranes. Without this component, the cell membrane becomes more permeable and its contents leak out. Econazole can also interfere with fungal respiration, membrane phospholipids, yeast transformation, purine uptake, and triglyceride or phospholipid biosynthesis.

When to interrupt dosage

The measure of Spectazole is contingent upon the diagnosed condition, including Cellulitis, Tinea cruris and Fungal eye infections. The dosage fluctuates, in accordance with the technique of delivery (e.g. Cream - Topical or Topical) detailed in the table beneath.
Condition
Dosage
Administration
Ringworm
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Fungal eye infections
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Atopic Dermatitis
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Intertrigo
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Skin
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Balanitis candida
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
cutaneous candidiasis
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Tinea Pedis
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Tinea Pedis
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
severe local inflammatory reactions
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Eczema
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Tinea Versicolor
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Inflammation
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
cutaneous dermatophyte infection
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Skin candida
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Cellulitis
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Shingles
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Tinea cruris
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Tinea
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit
Mycoses
, 0.01 mg/mg, 10.0 mg, 150.0 mg, 1.0 %, 10.0 mg/mL
, Topical, Cream, Cream - Topical, Vaginal, Suppository, Suppository - Vaginal, Aerosol, foam, Aerosol, foam - Topical, Cream - Vaginal, Solution, Solution - Topical, Kit - Topical, Kit

Warnings

There are 20 known major drug interactions with Spectazole.
Common Spectazole Drug Interactions
Drug Name
Risk Level
Description
Alfuzosin
Major
The metabolism of Alfuzosin can be decreased when combined with Econazole.
Avanafil
Major
The metabolism of Avanafil can be decreased when combined with Econazole.
Bromocriptine
Major
The serum concentration of Bromocriptine can be increased when it is combined with Econazole.
Cabergoline
Major
The serum concentration of Cabergoline can be increased when it is combined with Econazole.
Cariprazine
Major
The metabolism of Cariprazine can be decreased when combined with Econazole.
Spectazole Toxicity & Overdose RiskTo date, no cases of econazole overdose in humans have been reported. In animal studies, a toxic dose of econazole was found to be 462mg/kg in mice, 668mg/kg in rats, 272mg/kg in guinea pigs, and over 160mg/kg in dogs.

Spectazole Novel Uses: Which Conditions Have a Clinical Trial Featuring Spectazole?

303 active studies are currently being conducted to determine the efficacy of Spectazole in treating Atopic Dermatitis, Eczema and Cellulitis.
Condition
Clinical Trials
Trial Phases
Cellulitis
0 Actively Recruiting
Tinea Versicolor
0 Actively Recruiting
Tinea
0 Actively Recruiting
Inflammation
64 Actively Recruiting
Not Applicable, Early Phase 1, Phase 1, Phase 2, Phase 3, Phase 4
Skin candida
0 Actively Recruiting
Fungal eye infections
0 Actively Recruiting
Tinea Pedis
0 Actively Recruiting
Intertrigo
0 Actively Recruiting
Atopic Dermatitis
9 Actively Recruiting
Phase 2, Not Applicable, Phase 3, Phase 4
Eczema
0 Actively Recruiting
Ringworm
0 Actively Recruiting
Balanitis candida
0 Actively Recruiting
Tinea Pedis
0 Actively Recruiting
cutaneous candidiasis
0 Actively Recruiting
Skin
0 Actively Recruiting
Mycoses
0 Actively Recruiting
Tinea cruris
0 Actively Recruiting
severe local inflammatory reactions
0 Actively Recruiting
Shingles
4 Actively Recruiting
Phase 2, Phase 1
cutaneous dermatophyte infection
0 Actively Recruiting

Spectazole Reviews: What are patients saying about Spectazole?

5Patient Review
10/18/2008
Spectazole for Skin Infection due to a Candida Yeast
Lotrisone has been a miracle drug for me. I've used it for about 10 years to combat rashes in my groin area caused by sweat, and it's always worked within two days.
5Patient Review
12/1/2008
Spectazole for Ringworm of the Body
We tried over-the-counter treatments for three weeks, but it only seemed to make the symptoms worse. Then the doctor prescribed Spectazole. It was a miracle! Within a week you couldn't even see it, but we continued the treatment as directed. THANK YOU!
5Patient Review
9/18/2008
Spectazole for Inflammation and Infection of Nail Cuticle
I was using Penlac for three years with little to show for it. This new medication corrected the problem in just three months.
3Patient Review
8/7/2009
Spectazole for Ringworm of the Body
While this treatment is easy to use and did clear up my ringworm, I found the side effects incredibly severe. My skin was constantly itchy, burning, red, and peeling.
2.3Patient Review
7/3/2013
Spectazole for Athlete's Foot
Unfortunately, this treatment caused me to break out in pimples, blisters, and red spots just three days after I started using it. It was terrible, and I'm 73 years old.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about spectazole

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How long does it take for econazole cream to work?

"It usually takes around a week or two for people to start seeing improvement in their symptoms after using econazole cream. However, it's important to use the cream for the recommended amount of time indicated on the packaging (which is usually 2 weeks for most conditions, and 1 month for athlete's foot), even if your symptoms have mostly gone away."

Answered by AI

What is nitrate cream used for?

"This medicine works by killing the fungi that cause these infections.

Econazole nitrate cream is a cream used to treat fungal infections of the skin. It works by killing the fungi that cause infection."

Answered by AI

What's econazole used for?

"Econazole foam is a prescription medication used to treat ringworm of the foot (interdigital tinea pedis; athlete's foot). It is available as a cream."

Answered by AI

What is Spectazole cream used for?

"Econazole is used to treat fungal infections of the skin such as athlete's foot, jock itch, and ringworm. This medication is also used to treat pityriasis (tinea versicolor), a fungal infection that causes lightening or darkening of the skin on the neck, chest, arms, or legs."

Answered by AI

Clinical Trials for Spectazole

Have you considered Spectazole clinical trials? We made a collection of clinical trials featuring Spectazole, we think they might fit your search criteria.
Have you considered Spectazole clinical trials? We made a collection of clinical trials featuring Spectazole, we think they might fit your search criteria.
Have you considered Spectazole clinical trials? We made a collection of clinical trials featuring Spectazole, we think they might fit your search criteria.
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