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Almond Oil for Hyperpigmentation

Phase 4
Waitlist Available
Led By Raja Sivamani, MD MS AP
Research Sponsored by University of California, Davis
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 16 weeks
Awards & highlights

Study Summary

This trial will compare how well almond oil and hydroquinone lighten skin and change the skin's microbiome.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~16 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 16 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Secondary outcome measures
Appearance of facial redness
Intensity of facial pigment
Quantification for the presence of species within the genus Cutibacteria, Staphyloccoccus, and Ralstonia
+2 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Almond oilExperimental Treatment1 Intervention
Almond Oil Pressed Cold
Group II: HydroquinoneActive Control1 Intervention
Hydroquinone 2% cream

Find a Location

Who is running the clinical trial?

University of California, DavisLead Sponsor
910 Previous Clinical Trials
4,706,941 Total Patients Enrolled
Raja Sivamani, MD MS APPrincipal InvestigatorUC Davis Dermatology
4 Previous Clinical Trials
146 Total Patients Enrolled
1 Trials studying Hyperpigmentation
22 Patients Enrolled for Hyperpigmentation

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Has the FDA sanctioned Almond Oil for therapeutic purposes?

"Through clinical trials, our team has determined that Almond Oil is safe to use and received a score of 3. This final stage trial confirms the efficacy and safety of this product."

Answered by AI

Are there any current openings in the clinical trial?

"Affirmative. Clinicaltrials.gov information reveals that this investigation, which was initially published on July 1st 2021, is actively recruiting patients. Fifty individuals need to be brought into the study from a single medical site."

Answered by AI

What is the capacity of this trial for participants?

"Affirmative. Clinicaltrials.gov has information confirming that registration for this medical trial is open, and the study was first posted on July 1st 2021 with its most recent update being November 23rd 2022. The research requires 50 participants to join from a single clinical site."

Answered by AI

Are there any documented studies showing the efficacy of Almond Oil in a clinical setting?

"Currently, there is one active trial of almond oil in progress; however, no trials have reached phase 3 yet. Most studies with this substance are occurring in Sacramento, California although a single site has also been established for clinical research on the topic."

Answered by AI

What is the common therapeutic application for Almond Oil?

"Almond Oil is primarily prescribed to patients suffering from melasma, however it may also benefit those with sun exposure-related hyperpigmentation or acne."

Answered by AI

Who else is applying?

What portion of applicants met pre-screening criteria?
Did not meet criteria

Why did patients apply to this trial?

I have tried and continue to try many things, including changing my diet.
PatientReceived 2+ prior treatments
~13 spots leftby Apr 2025