Time Restricted Eating During Chemotherapy for Breast Cancer
Trial Summary
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of the treatment Time Restricted Eating during chemotherapy for breast cancer?
Is time-restricted eating safe for humans?
How is time-restricted eating during chemotherapy for breast cancer different from other treatments?
Time-restricted eating (TRE) during chemotherapy for breast cancer is unique because it involves limiting eating to an 8-hour window each day, which may help protect healthy cells and make cancer cells more vulnerable to chemotherapy. This approach is different from traditional treatments as it combines dietary timing with chemotherapy, potentially reducing side effects and improving treatment effectiveness.110111213
What is the purpose of this trial?
Breast cancer is the most common cancer in the United States however, little is known about how diet can affect cancer treatment. Pre-clinical murine studies report intermittent fasting increases effectiveness of chemotherapy and decreases treatment related adverse events. The proposed research will demonstrate that time restricted eating, a form of intermittent fasting, will improve treatment related outcomes, patient related outcomes, and limit treatment related weight gain and fat mass accretion.Time restricted eating combined with a mediterranean diet will also be feasible and improve cardiometabolic risk more than TRE alone or standard care.
Research Team
Kelsey Gabel, MS, RD, PhD
Principal Investigator
UIC
Eligibility Criteria
This trial is for women aged 25-99 with Stage I-III breast cancer, who are not pregnant or breastfeeding, do not have severe heart conditions, hepatitis, diabetes, eating disorders, a BMI outside of 25-40kg/m2 range or other major health issues. Participants must be able to follow the study procedures and provide consent.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Chemotherapy Treatment
Participants undergo chemotherapy while following either time restricted eating or a Mediterranean diet within an 8-hour window
Follow-up
Participants are monitored for safety and effectiveness after treatment, including body composition, treatment side effects, and metabolic markers
Treatment Details
Interventions
- 8-h time restricted eating
- MedTRE
- TRE
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Illinois at Chicago
Lead Sponsor