Your session is about to expire
What is Gris-Peg
GriseofulvinThe Generic name of this drug
Treatment SummaryGriseofulvin is an antibiotic medication used to treat fungal infections of the skin, hair, and nails. It is taken by mouth and works by stopping the growth of certain types of fungi.
Griseofulvin MICROSIZEis the brand name
Gris-Peg Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Griseofulvin MICROSIZE
Griseofulvin
1971
41
Approved as Treatment by the FDA
Griseofulvin, otherwise known as Griseofulvin MICROSIZE, is approved by the FDA for 6 uses including Tinea Corporis and Tinea Pedis .Tinea Corporis
Tinea Pedis
Kerion Celsi
Tinea barbae
Tinea Unguium
Tinea cruris
Effectiveness
How Gris-Peg Affects PatientsGriseofulvin is a drug used for over 40 years to treat fungal skin infections. It works when taken orally and binds to the affected area of skin, making it harder for fungus to grow. Griseofulvin also binds to the microtubules of the fungus which stops its growth process. It does not work against bacteria or other types of fungi.
How Gris-Peg works in the bodyGriseofulvin stops the growth of fungi by interfering with its cell division and nucleic acid production. It binds to human keratin and then binds to fungal microtubules when it reaches the fungal site, which stops the fungal cells from dividing properly.
When to interrupt dosage
The suggested dosage of Gris-Peg is contingent upon the diagnosed condition, such as Tinea cruris, Tinea barbae and Tinea Unguium. Amount of dosage deviates, according to the administration approach demonstrated in the table below.Condition
Dosage
Administration
Tinea cruris
, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg
, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Tinea Pedis
, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg
, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Tinea Corporis
, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg
, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Tinea barbae
, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg
, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Tinea Unguium
, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg
, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Kerion Celsi
, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg
, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Warnings
Gris-Peg ContraindicationsCondition
Risk Level
Notes
Porphyria
Do Not Combine
hepatocellular failure
Do Not Combine
Common Gris-Peg Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Griseofulvin.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Griseofulvin.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Griseofulvin.
Alpelisib
Major
The metabolism of Alpelisib can be increased when combined with Griseofulvin.
Aminophylline
Major
The metabolism of Aminophylline can be increased when combined with Griseofulvin.
Gris-Peg Toxicity & Overdose RiskThe most common side effects of taking this drug are headaches, stomach discomfort, and skin reactions.
Gris-Peg Novel Uses: Which Conditions Have a Clinical Trial Featuring Gris-Peg?
No active clinical trials are currently in progress to explore the potential of Gris-Peg in providing relief from Tinea Corporis, Tinea barbae and Tinea Pedis.Condition
Clinical Trials
Trial Phases
Tinea Pedis
0 Actively Recruiting
Tinea Corporis
0 Actively Recruiting
Tinea barbae
0 Actively Recruiting
Tinea Unguium
0 Actively Recruiting
Tinea cruris
0 Actively Recruiting
Kerion Celsi
0 Actively Recruiting
Gris-Peg Reviews: What are patients saying about Gris-Peg?
5Patient Review
11/20/2009 We're two weeks in and my daughter's fungus has cleared up. Her toes are still a bit discolored, but we're continuing the medication as prescribed. So far, no side effects to speak of.
5Patient Review
6/14/2009 This treatment is effective.
4.7Patient Review
3/14/2008 I had a fungal infection under my right big toenail. It took several months of treatment, but eventually healed completely without any apparent side effects.
3.7Patient Review
7/30/2010 I had a sore throat, gums that were sore, cramping stomach, severe chills, fever and flu-like symptoms. I stopped taking the pills and conditions slowly improved. I took the pills for about a week before seeing the doctor who told me to stop taking them. The one good thing is they think the ringworm is gone now.
3.3Patient Review
8/4/2010 I was on this treatment for a couple of weeks. It cleared up my scalp infection within days, but then it came back worse a few weeks later. I started taking it again and experienced severe insomnia and diarrhea for the first few days. It's really frustrating not being able to sleep, but the upside is that it does reduce the scalp symptoms fairly quickly.
3Patient Review
12/1/2009 The initial 30 days of this treatment went well, but the infection didn't go away. The dermatologist upped the dosage, and I had a reaction to it on the third time taking the increased dose. I got hives all over my body and had to go to the ER. Haven't taken it since, and have been dealing with the infection for 5 years now.
2.3Patient Review
5/22/2010 I had a really terrible experience with this drug. I felt like I had the flu - headache, runny nose, coughing, sneezing, lack of sleep. And after just one week taking the medication, my ringworm came back!
2Patient Review
3/16/2012 I unfortunately have not seen any improvement after taking Gris-Peg for two months now. Additionally, it regularly makes me feel nauseous and gives me terrible dreams at night.
1.7Patient Review
2/20/2009 I cannot attest to the efficacy of this medication as I had two very bad experiences after taking it. The first was an allergic reaction that manifested in a horrible rash, and the second time I took it I woke up a few hours later having trouble breathing. Needless to say, I will not be taking this again.
1.7Patient Review
2/8/2008 My son was treated with this for almost a year, but we took him off because it wasn't clearing the ringworm. The cortizone cream alone actually worked better. He's been off for two months and still complains of headaches and stomach aches. I wouldn't recommend it.
1.7Patient Review
10/4/2010 My son has been taking Gris-peg for 27 days to treat his scalp ringworm, but it has not worked. If anything, the problem has gotten worse.
1.7Patient Review
1/4/2010 I was prescribed Gris-Peg for an aggressive fingernail fungus a few years ago, but I had to stop taking it almost immediately because of the awful side effects. In my opinion, there are other more effective products available today.
1Patient Review
10/19/2009 I had to stop taking Gris PEG Oral after only ten days because it started giving me a heart palpitation about five minutes after ingestion. I also had swelling in my face and genitals, as well as difficulty sleeping. It was an absolutely terrible experience overall.
1Patient Review
4/10/2010 Unfortunately, I had to stop taking this medication after only a few days because I developed a severe rash all over my body.
Patient Q&A Section about gris-peg
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the most common side effect of griseofulvin?
"The following symptoms may occur: headache, nausea, vomiting, diarrhea, stomach upset, tiredness, dizziness, or difficulty sleeping."
Answered by AI
What is griseofulvin used for?
"This medicine is used to treat fungus infections of the body, feet, groin and thighs, scalp, skin, fingernails, and toenails. It may be taken alone or used along with medicines that are applied to the skin for fungus infections."
Answered by AI
What is Gris-PEG 250 mg used for?
"This drug is used to treat fungal infections of the skin, hair, and nails. Such infections often cause symptoms such as itching, red/peeling/scaly skin, and discolored nails. Treating these infections can help reduce these symptoms."
Answered by AI
How long does it take for griseofulvin to work?
"It takes around two to four weeks for skin infections to clear up when taking griseofulvin, and four to six weeks for hair and scalp infections."
Answered by AI