Gris-Peg

Tinea Pedis, Tinea barbae, Kerion Celsi + 3 more

Treatment

11 FDA approvals

0 Active Studies for Gris-Peg

What is Gris-Peg

Griseofulvin

The Generic name of this drug

Treatment Summary

Griseofulvin is an antibiotic medication used to treat fungal infections of the skin, hair, and nails. It is taken by mouth and works by stopping the growth of certain types of fungi.

Griseofulvin MICROSIZE

is the brand name

image of different drug pills on a surface

Gris-Peg Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Griseofulvin MICROSIZE

Griseofulvin

1971

41

Approved as Treatment by the FDA

Griseofulvin, otherwise known as Griseofulvin MICROSIZE, is approved by the FDA for 11 uses including Tinea Cruris and Tinea Corporis .

Tinea Cruris

Tinea Corporis

Tinea Unguium

Tinea Capitis

Tinea Pedis

Tinea barbae

Tinea Cruris

Kerion Celsi

Onychomycosis

Foot

Tinea

Effectiveness

How Gris-Peg Affects Patients

Griseofulvin is a drug used for over 40 years to treat fungal skin infections. It works when taken orally and binds to the affected area of skin, making it harder for fungus to grow. Griseofulvin also binds to the microtubules of the fungus which stops its growth process. It does not work against bacteria or other types of fungi.

How Gris-Peg works in the body

Griseofulvin stops the growth of fungi by interfering with its cell division and nucleic acid production. It binds to human keratin and then binds to fungal microtubules when it reaches the fungal site, which stops the fungal cells from dividing properly.

When to interrupt dosage

The suggested dosage of Gris-Peg is contingent upon the diagnosed condition, such as Tinea cruris, Tinea barbae and Tinea Unguium. Amount of dosage deviates, according to the administration approach demonstrated in the table below.

Condition

Dosage

Administration

Tinea barbae

, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg

, Oral, Tablet - Oral, Tablet, Suspension - Oral, Suspension, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated

Kerion Celsi

, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg

, Oral, Tablet - Oral, Tablet, Suspension - Oral, Suspension, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated

Tinea Cruris

, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg

, Oral, Tablet - Oral, Tablet, Suspension - Oral, Suspension, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated

Tinea Pedis

, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg

, Oral, Tablet - Oral, Tablet, Suspension - Oral, Suspension, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated

Tinea

, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg

, Oral, Tablet - Oral, Tablet, Suspension - Oral, Suspension, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated

Onychomycosis

, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg

, Oral, Tablet - Oral, Tablet, Suspension - Oral, Suspension, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated

Warnings

Gris-Peg Contraindications

Condition

Risk Level

Notes

Porphyrias

Do Not Combine

Liver Failure

Do Not Combine

There are 20 known major drug interactions with Gris-Peg.

Common Gris-Peg Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Griseofulvin.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be increased when combined with Griseofulvin.

Alectinib

Major

The metabolism of Alectinib can be increased when combined with Griseofulvin.

Alpelisib

Major

The metabolism of Alpelisib can be increased when combined with Griseofulvin.

Aminophylline

Major

The metabolism of Aminophylline can be increased when combined with Griseofulvin.

Gris-Peg Toxicity & Overdose Risk

The most common side effects of taking this drug are headaches, stomach discomfort, and skin reactions.

image of a doctor in a lab doing drug, clinical research

Gris-Peg Novel Uses: Which Conditions Have a Clinical Trial Featuring Gris-Peg?

No active clinical trials are currently in progress to explore the potential of Gris-Peg in providing relief from Tinea Corporis, Tinea barbae and Tinea Pedis.

Condition

Clinical Trials

Trial Phases

Tinea Pedis

0 Actively Recruiting

Tinea barbae

0 Actively Recruiting

Tinea

0 Actively Recruiting

Onychomycosis

0 Actively Recruiting

Tinea Cruris

0 Actively Recruiting

Kerion Celsi

0 Actively Recruiting

Gris-Peg Reviews: What are patients saying about Gris-Peg?

5

Patient Review

11/20/2009

Gris-Peg for Fungal Infection of Toenails

We're two weeks in and my daughter's fungus has cleared up. Her toes are still a bit discolored, but we're continuing the medication as prescribed. So far, no side effects to speak of.

5

Patient Review

6/14/2009

Gris-Peg for Ringworm of Scalp

This treatment is effective.

4.7

Patient Review

3/14/2008

Gris-Peg for Fungal Infection of Toenails

I had a fungal infection under my right big toenail. It took several months of treatment, but eventually healed completely without any apparent side effects.

3.7

Patient Review

7/30/2010

Gris-Peg for Ringworm of the Body

I had a sore throat, gums that were sore, cramping stomach, severe chills, fever and flu-like symptoms. I stopped taking the pills and conditions slowly improved. I took the pills for about a week before seeing the doctor who told me to stop taking them. The one good thing is they think the ringworm is gone now.

3.3

Patient Review

8/4/2010

Gris-Peg for Ringworm of Scalp

I was on this treatment for a couple of weeks. It cleared up my scalp infection within days, but then it came back worse a few weeks later. I started taking it again and experienced severe insomnia and diarrhea for the first few days. It's really frustrating not being able to sleep, but the upside is that it does reduce the scalp symptoms fairly quickly.

3

Patient Review

12/1/2009

Gris-Peg for Fungal Infection of Fingernails - Onychomycosis

The initial 30 days of this treatment went well, but the infection didn't go away. The dermatologist upped the dosage, and I had a reaction to it on the third time taking the increased dose. I got hives all over my body and had to go to the ER. Haven't taken it since, and have been dealing with the infection for 5 years now.

2.3

Patient Review

5/22/2010

Gris-Peg for Ringworm of the Body

I had a really terrible experience with this drug. I felt like I had the flu - headache, runny nose, coughing, sneezing, lack of sleep. And after just one week taking the medication, my ringworm came back!

2

Patient Review

3/16/2012

Gris-Peg for Athlete's Foot

I unfortunately have not seen any improvement after taking Gris-Peg for two months now. Additionally, it regularly makes me feel nauseous and gives me terrible dreams at night.

1.7

Patient Review

2/20/2009

Gris-Peg for Athlete's Foot

I cannot attest to the efficacy of this medication as I had two very bad experiences after taking it. The first was an allergic reaction that manifested in a horrible rash, and the second time I took it I woke up a few hours later having trouble breathing. Needless to say, I will not be taking this again.

1.7

Patient Review

2/8/2008

Gris-Peg for Ringworm of Scalp

My son was treated with this for almost a year, but we took him off because it wasn't clearing the ringworm. The cortizone cream alone actually worked better. He's been off for two months and still complains of headaches and stomach aches. I wouldn't recommend it.

1.7

Patient Review

10/4/2010

Gris-Peg for Ringworm of Scalp

My son has been taking Gris-peg for 27 days to treat his scalp ringworm, but it has not worked. If anything, the problem has gotten worse.

1.7

Patient Review

1/4/2010

Gris-Peg for Fungal Infection of Fingernails - Onychomycosis

I was prescribed Gris-Peg for an aggressive fingernail fungus a few years ago, but I had to stop taking it almost immediately because of the awful side effects. In my opinion, there are other more effective products available today.

1

Patient Review

10/19/2009

Gris-Peg for Fungal Infection of Toenails

I had to stop taking Gris PEG Oral after only ten days because it started giving me a heart palpitation about five minutes after ingestion. I also had swelling in my face and genitals, as well as difficulty sleeping. It was an absolutely terrible experience overall.

1

Patient Review

4/10/2010

Gris-Peg for Fungal Infection of Fingernails - Onychomycosis

Unfortunately, I had to stop taking this medication after only a few days because I developed a severe rash all over my body.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about gris-peg

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the most common side effect of griseofulvin?

"The following symptoms may occur: headache, nausea, vomiting, diarrhea, stomach upset, tiredness, dizziness, or difficulty sleeping."

Answered by AI

What is griseofulvin used for?

"This medicine is used to treat fungus infections of the body, feet, groin and thighs, scalp, skin, fingernails, and toenails. It may be taken alone or used along with medicines that are applied to the skin for fungus infections."

Answered by AI

What is Gris-PEG 250 mg used for?

"This drug is used to treat fungal infections of the skin, hair, and nails. Such infections often cause symptoms such as itching, red/peeling/scaly skin, and discolored nails. Treating these infections can help reduce these symptoms."

Answered by AI

How long does it take for griseofulvin to work?

"It takes around two to four weeks for skin infections to clear up when taking griseofulvin, and four to six weeks for hair and scalp infections."

Answered by AI