Thera-Clean Microbubbles for Atopic Dermatitis
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests Thera-Clean® Microbubbles, a new chemical-free treatment, to determine its effectiveness in improving skin conditions like eczema and psoriasis. The microbubbles aim to clean and soothe inflamed skin, potentially reducing itchiness and aiding healing. People with stable skin conditions such as psoriasis, eczema, epidermolysis bullosa (a condition causing fragile skin), or ichthyosis (a disorder leading to dry, scaly skin) might be suitable for this trial. Participants will use the Thera-Clean system in home baths while continuing their current skin care routine. As an Early Phase 1 trial, this research focuses on understanding how the treatment works in people, offering participants the opportunity to be among the first to experience this innovative approach.
Do I need to stop my current medications for the trial?
No, you can continue using your usual skin treatment routine during the study.
What prior data suggests that the Thera-Clean® Microbubbles System is safe for human use?
Research has shown that Thera-Clean® Microbubbles have been safely used on animals, particularly dogs with sensitive skin. The treatment is designed to be gentle and avoid causing additional skin irritation. Although limited information exists about its use in humans, researchers are currently studying its effects on skin conditions like atopic dermatitis, a type of eczema that causes itchy and inflamed skin.
This study is in an early phase, focusing on how well people tolerate the treatment and identifying any side effects. Early-phase studies are the first step in testing new treatments in humans, so there may be less information about side effects compared to later studies. However, given the treatment's gentle nature in animal studies, it may also be well-tolerated in humans.12345Why do researchers think this study treatment might be promising?
Unlike the standard treatments for atopic dermatitis, which typically include topical steroids and moisturizers, the Thera-Clean Microbubbles system offers a unique approach by using microbubbles in a bath system. This method gently cleanses the skin without the use of harsh chemicals, which can be a game-changer for people with sensitive skin. Researchers are excited about its potential to soothe inflammation and improve skin health through a non-invasive, drug-free method that could reduce reliance on traditional medications.
What evidence suggests that the Thera-Clean Microbubbles System is effective for atopic dermatitis?
Research has shown that Thera-Clean® Microbubble technology may improve skin conditions in animals. This chemical-free treatment cleans dirt and other substances from hair follicles, reducing itching and aiding healing. Early studies suggest that these microbubbles can heal inflamed and damaged skin, benefiting conditions like atopic dermatitis. The trial will evaluate the effectiveness of the Thera-Clean Microbubbles bath system for participants using the device at home. Although direct evidence in humans is limited, the technology shows promise for improving skin health in people with inflammatory skin diseases.12678
Who Is on the Research Team?
Amy Paller, MD
Principal Investigator
Northwestern University
Are You a Good Fit for This Trial?
This trial is for individuals with certain skin conditions such as xeroderma, atopic dermatitis, epidermolysis bullosa, ichthyosis, and psoriasis. Participants should have a diagnosis of one of these inflammatory skin diseases to be eligible.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive Thera-Clean® Microbubble therapy for skin conditions
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Thera-Clean® Microbubbles System
Find a Clinic Near You
Who Is Running the Clinical Trial?
Northwestern University
Lead Sponsor