Ulesfia

Sunburn, minor burns, Herpes Labialis + 7 more

Treatment

2 Active Studies for Ulesfia

What is Ulesfia

Benzyl alcohol

The Generic name of this drug

Nitrotan

is the brand name

image of different drug pills on a surface

Ulesfia Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Nitrotan

Benzyl alcohol

1992

8

Effectiveness

How Ulesfia works in the body

Benzyl alcohol works by blocking the breathing holes of lice, causing them to suffocate.

When to interrupt dosage

The quantity of Ulesfia is contingent upon the diagnosed disorder, encompassing Head, abrasions and superficial Wounds. The dosage is likewise determined by the technique of administration featured in the subsequent table.

Condition

Dosage

Administration

Corneal Injuries

0.1 mg/mg, , 0.105 mg/mg, 5.0 mL/mL, 0.05 mg/mg, 0.01 mg/mg, 5.0 mg/mL, 0.84 %, 1.07 %, 2.5 %, 4.0 %, 10.0 %, 1.0 %, 0.1 mL/mL, 100.0 mg/mL, 9.0 mg/mL, 2.91 mg/mL, 190.0 mg/mL, 1.0 mL/mL, 0.061 mg/mg, 10.0 mg/mL, 9.93 mg/mL, 0.1 mg/mL, 0.4386 %, 3.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 2.7 mg/mL

, Gel - Topical, Gel, Topical, Cream, Cream - Topical, Liquid, Liquid - Topical, Lotion, Lotion - Topical, Ointment - Topical, Gel - Buccal; Topical, Spray - Topical, Suspension, Auricular (otic), Suspension - Auricular (otic), Spray, Gel - Dental, Lotion - Dental, Liquid - Percutaneous; Topical; Transdermal, Solution - Topical, Aerosol, spray - Topical, Oral, Solution - Oral, Solution, Kit, Oral; Topical, Kit - Oral; Topical, Dental, Ointment, Buccal; Topical, Cream - Percutaneous; Topical; Transdermal, Percutaneous; Topical; Transdermal, Aerosol, spray

superficial Wounds

0.1 mg/mg, , 0.105 mg/mg, 5.0 mL/mL, 0.05 mg/mg, 0.01 mg/mg, 5.0 mg/mL, 0.84 %, 1.07 %, 2.5 %, 4.0 %, 10.0 %, 1.0 %, 0.1 mL/mL, 100.0 mg/mL, 9.0 mg/mL, 2.91 mg/mL, 190.0 mg/mL, 1.0 mL/mL, 0.061 mg/mg, 10.0 mg/mL, 9.93 mg/mL, 0.1 mg/mL, 0.4386 %, 3.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 2.7 mg/mL

, Gel - Topical, Gel, Topical, Cream, Cream - Topical, Liquid, Liquid - Topical, Lotion, Lotion - Topical, Ointment - Topical, Gel - Buccal; Topical, Spray - Topical, Suspension, Auricular (otic), Suspension - Auricular (otic), Spray, Gel - Dental, Lotion - Dental, Liquid - Percutaneous; Topical; Transdermal, Solution - Topical, Aerosol, spray - Topical, Oral, Solution - Oral, Solution, Kit, Oral; Topical, Kit - Oral; Topical, Dental, Ointment, Buccal; Topical, Cream - Percutaneous; Topical; Transdermal, Percutaneous; Topical; Transdermal, Aerosol, spray

Sunburn

0.1 mg/mg, , 0.105 mg/mg, 5.0 mL/mL, 0.05 mg/mg, 0.01 mg/mg, 5.0 mg/mL, 0.84 %, 1.07 %, 2.5 %, 4.0 %, 10.0 %, 1.0 %, 0.1 mL/mL, 100.0 mg/mL, 9.0 mg/mL, 2.91 mg/mL, 190.0 mg/mL, 1.0 mL/mL, 0.061 mg/mg, 10.0 mg/mL, 9.93 mg/mL, 0.1 mg/mL, 0.4386 %, 3.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 2.7 mg/mL

, Gel - Topical, Gel, Topical, Cream, Cream - Topical, Liquid, Liquid - Topical, Lotion, Lotion - Topical, Ointment - Topical, Gel - Buccal; Topical, Spray - Topical, Suspension, Auricular (otic), Suspension - Auricular (otic), Spray, Gel - Dental, Lotion - Dental, Liquid - Percutaneous; Topical; Transdermal, Solution - Topical, Aerosol, spray - Topical, Oral, Solution - Oral, Solution, Kit, Oral; Topical, Kit - Oral; Topical, Dental, Ointment, Buccal; Topical, Cream - Percutaneous; Topical; Transdermal, Percutaneous; Topical; Transdermal, Aerosol, spray

minor burns

0.1 mg/mg, , 0.105 mg/mg, 5.0 mL/mL, 0.05 mg/mg, 0.01 mg/mg, 5.0 mg/mL, 0.84 %, 1.07 %, 2.5 %, 4.0 %, 10.0 %, 1.0 %, 0.1 mL/mL, 100.0 mg/mL, 9.0 mg/mL, 2.91 mg/mL, 190.0 mg/mL, 1.0 mL/mL, 0.061 mg/mg, 10.0 mg/mL, 9.93 mg/mL, 0.1 mg/mL, 0.4386 %, 3.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 2.7 mg/mL

, Gel - Topical, Gel, Topical, Cream, Cream - Topical, Liquid, Liquid - Topical, Lotion, Lotion - Topical, Ointment - Topical, Gel - Buccal; Topical, Spray - Topical, Suspension, Auricular (otic), Suspension - Auricular (otic), Spray, Gel - Dental, Lotion - Dental, Liquid - Percutaneous; Topical; Transdermal, Solution - Topical, Aerosol, spray - Topical, Oral, Solution - Oral, Solution, Kit, Oral; Topical, Kit - Oral; Topical, Dental, Ointment, Buccal; Topical, Cream - Percutaneous; Topical; Transdermal, Percutaneous; Topical; Transdermal, Aerosol, spray

Herpes Labialis

0.1 mg/mg, , 0.105 mg/mg, 5.0 mL/mL, 0.05 mg/mg, 0.01 mg/mg, 5.0 mg/mL, 0.84 %, 1.07 %, 2.5 %, 4.0 %, 10.0 %, 1.0 %, 0.1 mL/mL, 100.0 mg/mL, 9.0 mg/mL, 2.91 mg/mL, 190.0 mg/mL, 1.0 mL/mL, 0.061 mg/mg, 10.0 mg/mL, 9.93 mg/mL, 0.1 mg/mL, 0.4386 %, 3.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 2.7 mg/mL

, Gel - Topical, Gel, Topical, Cream, Cream - Topical, Liquid, Liquid - Topical, Lotion, Lotion - Topical, Ointment - Topical, Gel - Buccal; Topical, Spray - Topical, Suspension, Auricular (otic), Suspension - Auricular (otic), Spray, Gel - Dental, Lotion - Dental, Liquid - Percutaneous; Topical; Transdermal, Solution - Topical, Aerosol, spray - Topical, Oral, Solution - Oral, Solution, Kit, Oral; Topical, Kit - Oral; Topical, Dental, Ointment, Buccal; Topical, Cream - Percutaneous; Topical; Transdermal, Percutaneous; Topical; Transdermal, Aerosol, spray

Oral Pain

0.1 mg/mg, , 0.105 mg/mg, 5.0 mL/mL, 0.05 mg/mg, 0.01 mg/mg, 5.0 mg/mL, 0.84 %, 1.07 %, 2.5 %, 4.0 %, 10.0 %, 1.0 %, 0.1 mL/mL, 100.0 mg/mL, 9.0 mg/mL, 2.91 mg/mL, 190.0 mg/mL, 1.0 mL/mL, 0.061 mg/mg, 10.0 mg/mL, 9.93 mg/mL, 0.1 mg/mL, 0.4386 %, 3.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 2.7 mg/mL

, Gel - Topical, Gel, Topical, Cream, Cream - Topical, Liquid, Liquid - Topical, Lotion, Lotion - Topical, Ointment - Topical, Gel - Buccal; Topical, Spray - Topical, Suspension, Auricular (otic), Suspension - Auricular (otic), Spray, Gel - Dental, Lotion - Dental, Liquid - Percutaneous; Topical; Transdermal, Solution - Topical, Aerosol, spray - Topical, Oral, Solution - Oral, Solution, Kit, Oral; Topical, Kit - Oral; Topical, Dental, Ointment, Buccal; Topical, Cream - Percutaneous; Topical; Transdermal, Percutaneous; Topical; Transdermal, Aerosol, spray

Herpes Labialis

0.1 mg/mg, , 0.105 mg/mg, 5.0 mL/mL, 0.05 mg/mg, 0.01 mg/mg, 5.0 mg/mL, 0.84 %, 1.07 %, 2.5 %, 4.0 %, 10.0 %, 1.0 %, 0.1 mL/mL, 100.0 mg/mL, 9.0 mg/mL, 2.91 mg/mL, 190.0 mg/mL, 1.0 mL/mL, 0.061 mg/mg, 10.0 mg/mL, 9.93 mg/mL, 0.1 mg/mL, 0.4386 %, 3.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 2.7 mg/mL

, Gel - Topical, Gel, Topical, Cream, Cream - Topical, Liquid, Liquid - Topical, Lotion, Lotion - Topical, Ointment - Topical, Gel - Buccal; Topical, Spray - Topical, Suspension, Auricular (otic), Suspension - Auricular (otic), Spray, Gel - Dental, Lotion - Dental, Liquid - Percutaneous; Topical; Transdermal, Solution - Topical, Aerosol, spray - Topical, Oral, Solution - Oral, Solution, Kit, Oral; Topical, Kit - Oral; Topical, Dental, Ointment, Buccal; Topical, Cream - Percutaneous; Topical; Transdermal, Percutaneous; Topical; Transdermal, Aerosol, spray

Insect Bites and Stings

0.1 mg/mg, , 0.105 mg/mg, 5.0 mL/mL, 0.05 mg/mg, 0.01 mg/mg, 5.0 mg/mL, 0.84 %, 1.07 %, 2.5 %, 4.0 %, 10.0 %, 1.0 %, 0.1 mL/mL, 100.0 mg/mL, 9.0 mg/mL, 2.91 mg/mL, 190.0 mg/mL, 1.0 mL/mL, 0.061 mg/mg, 10.0 mg/mL, 9.93 mg/mL, 0.1 mg/mL, 0.4386 %, 3.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 2.7 mg/mL

, Gel - Topical, Gel, Topical, Cream, Cream - Topical, Liquid, Liquid - Topical, Lotion, Lotion - Topical, Ointment - Topical, Gel - Buccal; Topical, Spray - Topical, Suspension, Auricular (otic), Suspension - Auricular (otic), Spray, Gel - Dental, Lotion - Dental, Liquid - Percutaneous; Topical; Transdermal, Solution - Topical, Aerosol, spray - Topical, Oral, Solution - Oral, Solution, Kit, Oral; Topical, Kit - Oral; Topical, Dental, Ointment, Buccal; Topical, Cream - Percutaneous; Topical; Transdermal, Percutaneous; Topical; Transdermal, Aerosol, spray

Skin Irritation

0.1 mg/mg, , 0.105 mg/mg, 5.0 mL/mL, 0.05 mg/mg, 0.01 mg/mg, 5.0 mg/mL, 0.84 %, 1.07 %, 2.5 %, 4.0 %, 10.0 %, 1.0 %, 0.1 mL/mL, 100.0 mg/mL, 9.0 mg/mL, 2.91 mg/mL, 190.0 mg/mL, 1.0 mL/mL, 0.061 mg/mg, 10.0 mg/mL, 9.93 mg/mL, 0.1 mg/mL, 0.4386 %, 3.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 2.7 mg/mL

, Gel - Topical, Gel, Topical, Cream, Cream - Topical, Liquid, Liquid - Topical, Lotion, Lotion - Topical, Ointment - Topical, Gel - Buccal; Topical, Spray - Topical, Suspension, Auricular (otic), Suspension - Auricular (otic), Spray, Gel - Dental, Lotion - Dental, Liquid - Percutaneous; Topical; Transdermal, Solution - Topical, Aerosol, spray - Topical, Oral, Solution - Oral, Solution, Kit, Oral; Topical, Kit - Oral; Topical, Dental, Ointment, Buccal; Topical, Cream - Percutaneous; Topical; Transdermal, Percutaneous; Topical; Transdermal, Aerosol, spray

Head

0.1 mg/mg, , 0.105 mg/mg, 5.0 mL/mL, 0.05 mg/mg, 0.01 mg/mg, 5.0 mg/mL, 0.84 %, 1.07 %, 2.5 %, 4.0 %, 10.0 %, 1.0 %, 0.1 mL/mL, 100.0 mg/mL, 9.0 mg/mL, 2.91 mg/mL, 190.0 mg/mL, 1.0 mL/mL, 0.061 mg/mg, 10.0 mg/mL, 9.93 mg/mL, 0.1 mg/mL, 0.4386 %, 3.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 2.7 mg/mL

, Gel - Topical, Gel, Topical, Cream, Cream - Topical, Liquid, Liquid - Topical, Lotion, Lotion - Topical, Ointment - Topical, Gel - Buccal; Topical, Spray - Topical, Suspension, Auricular (otic), Suspension - Auricular (otic), Spray, Gel - Dental, Lotion - Dental, Liquid - Percutaneous; Topical; Transdermal, Solution - Topical, Aerosol, spray - Topical, Oral, Solution - Oral, Solution, Kit, Oral; Topical, Kit - Oral; Topical, Dental, Ointment, Buccal; Topical, Cream - Percutaneous; Topical; Transdermal, Percutaneous; Topical; Transdermal, Aerosol, spray

Warnings

There are 20 known major drug interactions with Ulesfia.

Common Ulesfia Drug Interactions

Drug Name

Risk Level

Description

Aminophylline

Major

The metabolism of Aminophylline can be decreased when combined with Benzyl alcohol.

Amiodarone

Major

The metabolism of Amiodarone can be decreased when combined with Benzyl alcohol.

Amitriptyline

Major

The metabolism of Amitriptyline can be decreased when combined with Benzyl alcohol.

Amoxapine

Major

The metabolism of Amoxapine can be decreased when combined with Benzyl alcohol.

Astemizole

Major

The metabolism of Astemizole can be decreased when combined with Benzyl alcohol.

Ulesfia Toxicity & Overdose Risk

A toxic dose of the drug in rats has been found to be 1250mg/kg when administered orally, 400mg/kg when administered intraperitoneally, 2000mg/kg when administered subcutaneously, 53mg/kg when administered intravenously, and 2500mg/kg when administered orally to guinea pigs.

image of a doctor in a lab doing drug, clinical research

Ulesfia Novel Uses: Which Conditions Have a Clinical Trial Featuring Ulesfia?

Two active investigations are examining the potential of Ulesfia to relieve Cold Sore, Sunburn and Insect Bite symptoms.

Condition

Clinical Trials

Trial Phases

Herpes Labialis

0 Actively Recruiting

superficial Wounds

0 Actively Recruiting

Corneal Injuries

0 Actively Recruiting

Insect Bites and Stings

0 Actively Recruiting

minor burns

0 Actively Recruiting

Sunburn

1 Actively Recruiting

Not Applicable

Oral Pain

0 Actively Recruiting

Skin Irritation

0 Actively Recruiting

Head

1 Actively Recruiting

Not Applicable

Herpes Labialis

0 Actively Recruiting

Ulesfia Reviews: What are patients saying about Ulesfia?

5

Patient Review

1/10/2013

Ulesfia for Presence of Head Lice

Ulesfia is much more effective than Rid/Nix at getting rid of lice. We usually don't have to comb after treatment, and the second treatment seven days later takes care of any hatched bugs. Just remember to wash everything and vacuum.

3.7

Patient Review

3/25/2010

Ulesfia for Presence of Head Lice

I had tried a number of over-the-counter and prescription pesticide products on my daughter's hair without much success. Ulesfia was both more pleasant to use and more effective, which was great!

1

Patient Review

4/4/2011

Ulesfia for Presence of Head Lice

This was terrible and did not work at all.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about ulesfia

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Ulesfia discontinued?

"The Ulesfia brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available."

Answered by AI

How do you use benzyl alcohol for lice?

"Topical benzyl alcohol lotion is applied to the scalp and hair in two or three treatments, with the second treatment being applied about a week after the first. In some cases, a third treatment may be necessary."

Answered by AI

Is benzyl alcohol over the counter?

"Benzyl Alcohol is a medication that can be bought without a prescription to treat head lice. It comes in the form of a lotion to be applied externally to the scalp only. It is not covered by Medicare, and there is no generic alternative available."

Answered by AI

What is Ulesfia used for?

"Ulesfia is a prescription medication used to treat head lice. It may be used alone or with other medications. Ulesfia belongs to a class of drugs called Topical anti-infectives. It is not known if Ulesfia is safe and effective in children younger than 6 months of age."

Answered by AI

Clinical Trials for Ulesfia