Crestor

Hyperlipoproteinemia Type III, Hardening of the Arteries, Hyperlipidemia + 22 more

Treatment

16 FDA approvals

20 Active Studies for Crestor

Treatment for

Hyperlipoproteinemia Type III

What is Crestor

Rosuvastatin

The Generic name of this drug

Treatment Summary

Rosuvastatin, also known as Crestor, is a medication used to reduce the risk of cardiovascular disease by lowering cholesterol levels in the body. It belongs to a class of drugs called statins, which block the liver's production of cholesterol. It is commonly prescribed following cardiovascular events and to people with a moderate to high risk of developing cardiovascular disease. Rosuvastatin is known to be the most potent statin drug. It is generally effective and well-tolerated with minimal side effects or long-term effects. It is also less likely to interact with other medications compared to some other statins.

Crestor

is the brand name

image of different drug pills on a surface

Crestor Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Crestor

Rosuvastatin

2003

441

Approved as Treatment by the FDA

Rosuvastatin, otherwise known as Crestor, is approved by the FDA for 16 uses including primary Hyperlipidemia and Homozygous Familial Hypercholesterolaemia (HoFH) .

primary Hyperlipidemia

Homozygous Familial Hypercholesterolaemia (HoFH)

Hypertriglyceridemias

Coronary Artery Disease (CAD)

Helps manage Coronary Artery Disease (CAD)

Dyslipidemias

Dysbetalipoproteinemia

Heart Disease

Heterozygous Familial Hypercholesterolemia (HeFH)

Hyperlipidemia

Homozygous Familial Hypercholesterolemia

Hypertriglyceridemia

Hypercholesterolemia

Hardening of the Arteries

Helps manage Atherosclerosis

Coronary Disease

Helps manage Coronary Artery Disease (CAD)

Atherosclerotic Cardiovascular Diseases

Hyperlipoproteinemia Type III

Effectiveness

How Crestor Affects Patients

Rosuvastatin is a drug used to lower cholesterol. It reduces total cholesterol, LDL-cholesterol, Apolipoprotein B, non-HDL-cholesterol, and triglyceride levels while increasing HDL-cholesterol levels. High LDL-cholesterol, low HDL-cholesterol, and high triglyceride levels can lead to an increased risk of atherosclerosis and cardiovascular disease. Taking rosuvastatin can reduce this risk and decrease the chances of having a major cardiovascular event such as a heart attack, stroke, or coronary death. However, there is a risk of muscle pain, liver enzyme abnormalities, and changes in

How Crestor works in the body

Rosuvastatin works by blocking an enzyme that helps create cholesterol. When this happens, the liver produces more low density lipoprotein (LDL) receptors, which help pull LDL out of the blood. This leads to a decrease in LDL and very low density lipoprotein (VLDL) in the bloodstream. Studies have also shown that rosuvastatin has additional benefits outside of just cholesterol-lowering, such as improving the stability of atherosclerotic plaques, reducing oxidative stress, and inhibiting the thrombogenic response. It also affects leukocyte trafficking and T cell activation by binding to a

When to interrupt dosage

The measure of Crestor is contingent upon the diagnosed state, such as Diet, Dysbetalipoproteinemia and Heart Disease. The amount of dosage differs, as per the procedure of administration laid out in the table below.

Condition

Dosage

Administration

Hyperlipoproteinemia Type III