Byetta

Physical Activity, Type 2 Diabetes, Diet
Treatment
20 Active Studies for Byetta

What is Byetta

ExenatideThe Generic name of this drug
Treatment SummaryExenatide is a medication that helps to regulate blood sugar levels in patients with diabetes. It works by stimulating the GLP-1 receptor, which causes the pancreas to release insulin and reduces the production of glucagon. It also slows down the emptying of the stomach, helping to keep blood sugar levels stable. Exenatide was approved by the FDA in 2005.
Byettais the brand name
image of different drug pills on a surface
Byetta Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Byetta
Exenatide
2005
10

Effectiveness

How Byetta Affects PatientsExenatide helps your body better regulate its response to glucose. It signals your body to release more insulin and less glucagon when glucose is present, except in cases where you have low blood sugar, when a normal amount of glucagon is released. Exenatide also slows down the rate your stomach empties its contents, which helps regulate blood sugar and prevents both low and high blood sugar.
How Byetta works in the bodyExenatide activates a receptor in the body that helps balance levels of insulin and glucagon. This helps to keep blood sugar levels stable and prevents both high and low blood sugar. Exenatide also works to slow down the rate at which food leaves the stomach and decreases appetite, making it easier to maintain healthy blood sugar levels.

When to interrupt dosage

The dose of Byetta is contingent upon the pinpointed condition. The amount of dosage fluctuates, based on the method of delivery featured in the table beneath.
Condition
Dosage
Administration
Physical Activity
, 0.25 mg/mL, 0.005 mg, 0.01 mg, 2.0 mg, 20.0 mg/mL, 2.0 mg/dose, 0.005 mg/pump actuation, 0.01 mg/pump actuation
, Subcutaneous, Injection, Injection - Subcutaneous, Kit, Injection, solution, Injection, solution - Subcutaneous, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Subcutaneous, Solution, Solution - Subcutaneous, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Subcutaneous, Injection, suspension, extended release, Injection, suspension, extended release - Subcutaneous, Suspension, extended release, Suspension, extended release - Subcutaneous
Diet
, 0.25 mg/mL, 0.005 mg, 0.01 mg, 2.0 mg, 20.0 mg/mL, 2.0 mg/dose, 0.005 mg/pump actuation, 0.01 mg/pump actuation
, Subcutaneous, Injection, Injection - Subcutaneous, Kit, Injection, solution, Injection, solution - Subcutaneous, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Subcutaneous, Solution, Solution - Subcutaneous, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Subcutaneous, Injection, suspension, extended release, Injection, suspension, extended release - Subcutaneous, Suspension, extended release, Suspension, extended release - Subcutaneous
Type 2 Diabetes
, 0.25 mg/mL, 0.005 mg, 0.01 mg, 2.0 mg, 20.0 mg/mL, 2.0 mg/dose, 0.005 mg/pump actuation, 0.01 mg/pump actuation
, Subcutaneous, Injection, Injection - Subcutaneous, Kit, Injection, solution, Injection, solution - Subcutaneous, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Subcutaneous, Solution, Solution - Subcutaneous, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Subcutaneous, Injection, suspension, extended release, Injection, suspension, extended release - Subcutaneous, Suspension, extended release, Suspension, extended release - Subcutaneous

Warnings

Byetta has six contraindications. The utilization of Byetta should be avoided if you are afflicted with any of the conditions presented in the below table.Byetta Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Exenatide may interact with Pulse Frequency
There are 20 known major drug interactions with Byetta.
Common Byetta Drug Interactions
Drug Name
Risk Level
Description
(R)-warfarin
Moderate
Exenatide can cause an increase in the absorption of (R)-warfarin resulting in an increased serum concentration and potentially a worsening of adverse effects.
(S)-Warfarin
Moderate
Exenatide can cause an increase in the absorption of (S)-Warfarin resulting in an increased serum concentration and potentially a worsening of adverse effects.
2,4-thiazolidinedione
Moderate
The risk or severity of hypoglycemia can be increased when Exenatide is combined with 2,4-thiazolidinedione.
4-hydroxycoumarin
Moderate
Exenatide can cause an increase in the absorption of 4-hydroxycoumarin resulting in an increased serum concentration and potentially a worsening of adverse effects.
AICA ribonucleotide
Moderate
The risk or severity of hypoglycemia can be increased when Exenatide is combined with AICA ribonucleotide.
Byetta Toxicity & Overdose RiskAnimal studies have linked exenatide to deformities in fetal ribs and vertebrae and slower growth. High blood sugar levels during pregnancy can increase the risk of miscarriage. Exenatide should only be used during pregnancy if the benefits to mother and baby outweigh the risks. In mice, exenatide is found in breast milk, but the effects on breastfed babies is unknown. No data is available on the use of exenatide in children or elderly patients, though caution should be taken when prescribing to the elderly due to their increased risk of side effects. Patients with creatinine clearance of 50mL/min or
image of a doctor in a lab doing drug, clinical research

Byetta Novel Uses: Which Conditions Have a Clinical Trial Featuring Byetta?

162 active studies are presently assessing Byetta's capacity to mitigate symptoms associated with Type 2 Diabetes.
Condition
Clinical Trials
Trial Phases
Physical Activity
38 Actively Recruiting
Not Applicable, Phase 2, Phase 1, Early Phase 1
Type 2 Diabetes
190 Actively Recruiting
Phase 2, Not Applicable, Early Phase 1, Phase 1, Phase 4, Phase 3
Diet
3 Actively Recruiting
Not Applicable

Byetta Reviews: What are patients saying about Byetta?

5Patient Review
3/31/2015
Byetta for Additional Medication for Diabetes Type 2
Byetta completely stopped my kidney stones from forming.
5Patient Review
5/16/2017
Byetta for Type 2 Diabetes Mellitus
This drug made me so incredibly sick- to the point where I was vomiting uncontrollably and lost a significant amount of hair. I also couldn't sleep because I was so jittery. Needless to say, I will never take this again.
5Patient Review
5/17/2013
Byetta for Type 2 Diabetes Mellitus
The sharp pains in my stomach kept me up at night, to the point where my husband was getting frustrated. Thankfully, this treatment only took a month.
5Patient Review
1/9/2014
Byetta for Additional Medication for Diabetes Type 2
I'm really pleased with how Byetta has worked for me. Not only have my lab results improved, but I've also lost a significant amount of weight as a result of reduced appetite.
5Patient Review
11/23/2012
Byetta for Additional Medication for Diabetes Type 2
Byetta worked to decrease my need for insulin, but unfortunately also gave me such bad indigestion that I had to discontinue use.
4.3Patient Review
2/16/2016
Byetta for Additional Medication for Diabetes Type 2
This drug is effective at curbing your appetite and helping you to avoid overeating. However, it does cause stomach cramps which can be quite uncomfortable. Make sure you're near a bathroom when you take this medication!
4.3Patient Review
1/1/2013
Byetta for Additional Medication for Diabetes Type 2
I began using Byetta at the start of November and have been pleased with results so far. I've lost seven pounds, but my fasting sugar is still a bit high. I'm sure my doctor will increase the dosage when I see him. No bad reactions yet.
4Patient Review
7/19/2014
Byetta for Additional Medication for Diabetes Type 2
I am on my third pen and I am starting to see results now. It really makes me nauseous. ALSO, since I started with Byetta, I have been feeling more depressed. Is this a reported side effect?
4Patient Review
11/22/2012
Byetta for Additional Medication for Diabetes Type 2
3.7Patient Review
12/30/2017
Byetta for Additional Medication for Diabetes Type 2
I've been taking Byetta for a while now and it's helped me keep my A1C at 7.2, which is great.
3.3Patient Review
1/27/2015
Byetta for Type 2 Diabetes Mellitus
This drug has effectively managed my diabetes, and I've even lost weight and brought my A1C down. The only problem is that I can't increase the dosage because it gives me stomach issues. Also, has anyone else experienced chronic bladder infections after taking Byetta for an extended period of time?
3.3Patient Review
6/26/2014
Byetta for Additional Medication for Diabetes Type 2
I only took Byetta for a short while, but I experienced some really severe pain in my stomach and back. It felt like awful gas pressure without any of the benefits of actually passing gas. My doctor told me to stop taking it immediately, which I did. Thankfully, the pain is subsiding as time goes on.
2.7Patient Review
11/8/2015
Byetta for Type 2 Diabetes Mellitus
I'm on day two of the treatment and I haven't felt hungry at all. I had yogurt for breakfast and now I feel like I could vomit. I hope this doesn't last for two weeks like some people have said.
2.3Patient Review
12/9/2018
Byetta for Type 2 Diabetes Mellitus
I tried Byetta for a year, and it didn't help me at all. I'm going to tell my doctor that I'm stopping the medication.
2Patient Review
6/21/2014
Byetta for Type 2 Diabetes Mellitus
I lost all of my hair after starting this treatment. Thankfully, I stopped using it and saw a full reversal in the condition.
1.3Patient Review
2/8/2018
Byetta for Type 2 Diabetes Mellitus
The effect of this medication is excellent; however, the needle is large and difficult to use without drawing blood! It is also longer and bigger than an insulin pen, which makes it more difficult to use without pain.
1Patient Review
3/20/2016
Byetta for Type 2 Diabetes Mellitus
I was really disappointed when my insurance company stopped covering this medication. It did a great job of controlling my Type II diabetes, and the Victoza replacement simply isn't cutting it. I also tried Bydereon, but the needle was painfully large and it left a lump at the injection site.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about byetta

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Byetta still on the market?

"Bydureon is no longer available as of 2018. The two available formulations for exenatide are now Byetta and Bydureon BCise."

Answered by AI

Can Byetta be used for weight loss?

"No, Byetta is not approved for use as a weight-loss drug, however, because Byetta is used along with a healthy diet and exercise program, you may lose weight while using the drug. Additionally, studies show Byetta can cause a loss of appetite. This, too, may lead to weight loss."

Answered by AI

What does Byetta do to the body?

"Byetta lowers blood sugar after eating a meal, between meals, and during fasting periods. It can also help some people lose weight."

Answered by AI

Is Byetta better than metformin?

"Exenatide, sold under the brand name Byetta, is a medication used to treat diabetes mellitus type 2. It is injected subcutaneously twice a day.

Exenatide is used in addition to diet and exercise to lower blood sugar in people with type 2 diabetes. It is usually given together with other diabetes medications, such as metformin.

Exenatide may cause gastrointestinal side effects such as nausea, vomiting, diarrhea, and constipation. It may also cause weight loss."

Answered by AI

Clinical Trials for Byetta

Have you considered Byetta clinical trials? We made a collection of clinical trials featuring Byetta, we think they might fit your search criteria.
Have you considered Byetta clinical trials? We made a collection of clinical trials featuring Byetta, we think they might fit your search criteria.
Have you considered Byetta clinical trials? We made a collection of clinical trials featuring Byetta, we think they might fit your search criteria.