Study Summary
This trial will compare two methods of increasing the size of the jawbone, using a resorbable barrier membrane and either a bone graft with saline or a growth factor called rhPDGF.
- Osteoporosis
- Dental Implants
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
1 Primary · 1 Secondary · Reporting Duration: From baseline to 4 months
Trial Safety
Phase-Based Safety
Awards & Highlights
Trial Design
2 Treatment Groups
Allograft particles hydrated in a conventional way with saline.
1 of 2
Allograft particles hydrated with rhPDGF
1 of 2
Active Control
Experimental Treatment
44 Total Participants · 2 Treatment Groups
Primary Treatment: Allograft particles hydrated with rhPDGF · No Placebo Group · N/A
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18 - 99 · All Participants · 1 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Who else is applying?
What state do they live in?
| Georgia | 16.7% |
| New York | 16.7% |
| Florida | 8.3% |
| Other | 58.3% |
How old are they?
| 18 - 65 | 100.0% |
What site did they apply to?
| Unversity of Alabama at Birmingham, School of Dentistry | 100.0% |
What portion of applicants met pre-screening criteria?
| Met criteria | 100.0% |
Why did patients apply to this trial?
- "I don’t know if I am contacting the right people but I’m in desperate need of dental implants. It’s to the point where I don’t smile at all to embarrassing and I can’t afford them."
- "I am ready for a new smile. I am trying to further my career but looking angry due to a closed mouth isn't helping. I love when I'm told I'm beautiful but I hate smiling when It's told. I am not to far from Birmingham and I would love to be considered. Low income single mother raising two boys and being behind a computer for minimum pay trying to afford dental implants has been rough for at least 5 years plus keeping up with the economy"
How many prior treatments have patients received?
| 0 | 100.0% |
How responsive is this trial?
Average response time
- < 2 Days
Most responsive sites:
- Unversity of Alabama at Birmingham, School of Dentistry: < 48 hours
Typically responds via
| 100.0% | |
Frequently Asked Questions
Is eligibility for enrollment in this trial restricted to individuals over 25 years of age?
"Compatible with the requirements for taking part in this trial, individuals must be a minimum of 18 years old and no older than 99." - Anonymous Online Contributor
How can I become part of this medical research?
"This medical study seeks 44 volunteers, aged 18 to 99 years old and suffering from alopecia. Individuals must also be patients of the UAB Dental School with a need for implants in at least one quadrant of the mouth." - Anonymous Online Contributor
Is this experiment presently welcoming participants?
"Indeed, the information found on clinicaltrials.gov confirms that this medical research program is actively enrolling patients; it was first posted to the website on August 11th 2021 and has since been updated lastly on August 24th 2022. A total of 44 participants are needed for participation at a single site." - Anonymous Online Contributor
What is the upper bound of participants in this research endeavor?
"Affirmative. Clinicaltrials.gov attests that this study is actively recruiting for 44 patients at 1 site, which was initially posted on August 11th 2021 and revised recently on August 24th 2022." - Anonymous Online Contributor