PET/CT using PET ligands [F-18]FDG and [F-18]DPA-714 for Idiopathic Pulmonary Fibrosis

The University of Alabama at Birmingham, Birmingham, AL
Idiopathic Pulmonary FibrosisPET/CT using PET ligands [F-18]FDG and [F-18]DPA-714 - Drug
Eligibility
40 - 85
All Sexes

Study Summary

This trial is testing if two different imaging techniques can show evidence of lung inflammation and fibrosis in patients with idiopathic pulmonary fibrosis. The results may help guide future treatment decisions for patients with this condition.

Eligible Conditions
  • Idiopathic Pulmonary Fibrosis

Treatment Effectiveness

Phase-Based Effectiveness

1 of 3
Phase 1

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: screening to 48 hours post 2nd imaging visit.

Hour 48
Correlate quantitative PET measures of lung inflammation with [F-18]FDG and [F-18]DPA-714 to pulmonary function tests.

Trial Safety

Phase-Based Safety

1 of 3

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

1 Treatment Group

PET/CT using PET ligands [18F]FDG and [18F]DPA-714
1 of 1

Experimental Treatment

10 Total Participants · 1 Treatment Group

Primary Treatment: PET/CT using PET ligands [F-18]FDG and [F-18]DPA-714 · No Placebo Group · Phase 1

PET/CT using PET ligands [18F]FDG and [18F]DPA-714
Drug
Experimental Group · 1 Intervention: PET/CT using PET ligands [F-18]FDG and [F-18]DPA-714 · Intervention Types: Drug

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: screening to 48 hours post 2nd imaging visit.

Who is running the clinical trial?

University of Alabama at BirminghamLead Sponsor
1,475 Previous Clinical Trials
2,246,217 Total Patients Enrolled
5 Trials studying Idiopathic Pulmonary Fibrosis
1,189 Patients Enrolled for Idiopathic Pulmonary Fibrosis

Eligibility Criteria

Age 40 - 85 · All Participants · 0 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:

Frequently Asked Questions

Who has been deemed eligible to take part in this research?

"This research seeks 10 suitable individuals suffering from usual interstitial pneumonia aged between 40 and 85 to participate in the trial. The following criteria must be fulfilled: Age range of 40-85 years old, FEV1/FVC ratio greater than 0.70.." - Anonymous Online Contributor

Unverified Answer

What potential hazards could patients face when undergoing PET/CT with [F-18]FDG and [F-18]DPA-714?

"With limited data to support their safety and efficacy, PET/CT using PET ligands [F-18]FDG and [F-18]DPA-714 have been given a rating of 1." - Anonymous Online Contributor

Unverified Answer

Are individuals younger than 50 years of age allowed to join this experiment?

"Consistent with this clinical trial's inclusion criteria, the lower limit for enrollment is 40 years old and the upper limit 85." - Anonymous Online Contributor

Unverified Answer

Are there currently any open slots in this research trial?

"As recorded on clinicaltrials.gov, recruitment is still underway for this research endeavour that was first announced on December 8th 2020 and has been modified as recently as June 7th 2022." - Anonymous Online Contributor

Unverified Answer

What is the sample size for this clinical research project?

"Affirmative. The relevant information available on clinicaltrials.gov validates that this research is still searching for volunteers, having first been put up in December 8th 2020 and updated last June 7th 2022. This study requires 10 participants to be enrolled at one specific site." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.