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RefleXion PET/CT Imaging for Cancer

N/A

Recruiting

Led By Jeffrey Y Wong

Research Sponsored by City of Hope Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 72 hours

Awards & highlights

Study Summary

This trial compares PET-CT imaging using [18F]-FDG to RefleXion Medical Radiotherapy System (RMRS) imaging to potentially improve radiation therapy targeting of cancer cells.

Who is the study for?

This trial is for adults over 21 with various cancers who need standard PET-CT scans using [18F]-FDG for diagnosis or radiotherapy planning. It's not suitable for those with psychiatric/substance abuse issues, weigh over 450 pounds, or have lung/bone tumors previously studied.Check my eligibility

What is being tested?

The study compares the RefleXion Medical Radiotherapy System (RMRS) imaging to standard PET-CT scans in cancer patients. Researchers aim to enhance real-time radiotherapy targeting and reduce the number of scans needed by improving RMRS imaging quality.See study design

What are the potential side effects?

Since this trial focuses on imaging performance rather than drug effects, side effects are minimal but may include discomfort from lying still during scanning and exposure to low levels of radiation typical of diagnostic imaging procedures.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 72 hours

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 72 hours

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 72 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Imaging performance of X1 RefleXion Medical Radiotherapy System (RMRS) positron emission tomography (PET)-computed tomography (CT) with the Imaging performance of the diagnostic fludeoxyglucose F-18 ([18F]-FDG) PET-CT

Secondary outcome measures

Percent of cases where X1 RMRS PET data can be used to generate an acceptable biology-guided radiotherapy (BgRT) plan

Trial Design

1Treatment groups

Experimental Treatment

Group I: Device ([18F]-FDG PET-CT, X1 RMRS PET-CT)Experimental Treatment4 Interventions

Patients receive [18F]-FDG injection and undergo SOC [18F]-FDG PET-CT on study. Patients with at least one PET avid lesion then undergo X1 RMRS PET-CT imaging-only session on study.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Computed Tomography

2017

Completed Phase 2

~2720

Positron Emission Tomography

2008

Completed Phase 2

~2240

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

City of Hope Medical CenterLead Sponsor

565 Previous Clinical Trials

1,921,440 Total Patients Enrolled

National Cancer Institute (NCI)NIH

13,660 Previous Clinical Trials

40,924,662 Total Patients Enrolled

1 Trials studying Blood Cancers

70 Patients Enrolled for Blood Cancers

Jeffrey Y WongPrincipal InvestigatorCity of Hope Medical Center

8 Previous Clinical Trials

205 Total Patients Enrolled

Media Library

Medical Device Usage and Evaluation Clinical Trial Eligibility Overview. Trial Name: NCT05844306 — N/A

Blood Cancers Research Study Groups: Device ([18F]-FDG PET-CT, X1 RMRS PET-CT)

Blood Cancers Clinical Trial 2023: Medical Device Usage and Evaluation Highlights & Side Effects. Trial Name: NCT05844306 — N/A

Medical Device Usage and Evaluation 2023 Treatment Timeline for Medical Study. Trial Name: NCT05844306 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there currently an opportunity to join this experiment?

"The latest update on clinicaltrials.gov implies that this medical research is now welcoming applicants. This was first advertised on March 15th, 2023 and the most recent changes were made to the listing in May 3rd of the same year."

Answered by AI

How many participants are participating in this scientific experiment?

"Affirmative. According to the information on clinicaltrials.gov, this research project is actively enrolling participants at 1 location and a total of 20 individuals are required for completion. The trial was initially published on March 15th 2023 with its last update occurring on May 3rd2023."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

RefleXion PET/CT Imaging Performance in Patients With Various Malignancies

2023. "RefleXion PET/CT Imaging Performance in Patients With Various Malignancies". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05844306.