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PET Imaging for Neuropsychiatric Disorders
Study Summary
This trial will explore whether there is more inflammation in the brain of people with clinical evidence of neuropsychiatric syndromes.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Logistics
Participation is compensated
You will be compensated for participating in this trial.
Who is running the clinical trial?
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- I am not pregnant or breastfeeding.I am not a low affinity binder for PBR-28.I am between 18 and 45 years old.I am healthy or have a neuropsychiatric condition.I am between 18 and 80 years old.I can sit by myself for a long time without moving much.I am either male or female.I am healthy or have a neuropsychiatric condition like mood disorder or chronic pain.I am either male or female.I have not taken any medications for at least 14 days.I can sit still for a long time without help.
- Group 1: PET with radiotracer [11C]PBR-28 or [11C]ER176
- Group 2: PET with radiotracer [11C]PBR-28 or [11C]ER176 and affective challenge
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Has the Food and Drug Administration given its seal of approval to PET scans using [11C]PBR-28 or [11C]ER176?
"Our team at Power gave PET with radiotracer [11C]PBR-28 (or [11C]ER176) a score of 1 out of 3 as this is only in the initial testing phase, and there is limited data available on its safety or efficacy."
Is there an opportunity to participate in this experiment?
"This medical investigation is taking on 200 individuals of ages 18 to 45 who have neuropsychiatric conditions. The eligibility criteria include being either healthy without any neurological or psychiatric illness, having a diagnosed neuropsychiatric syndrome such as mood disorder or substance/alcohol use disorder, and the ability to sit still for prolonged periods of time with minimal body movement (in case of control volunteers)."
How many individuals are participating in the current research endeavor?
"Affirmative, the clinicaltrials.gov website attests that this research endeavor is actively seeking participants. Initially posted on May 1st 2017 and recently updated on September 27th 2021, it necessitates 200 volunteers from a single site for inclusion in the study."
Is there still availability for people to participate in this research venture?
"Affirmative, the details highlighted on clinicaltrials.gov demonstrate this research is presently recruiting participants. The study was first published on May 1st 2017 and has been revised as recently as September 27th 2021; 200 candidates are required from a single medical centre."
Does the research accept participants aged 18 and above?
"In line with the requirements for enrollment, prospective participants must be aged between 18 and 45."
Who else is applying?
What state do they live in?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
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