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Healthy Volunteers (cohort 1) for Healthy Subjects

Q: What criteria must be met to qualify for enrollment in this experiment?

To be eligible to join this trial, applicants must satisfy the criteria of being aged between 18 months and 89 years old with no pre-existing conditions. Aiming to recruit 28 volunteers in total.

Q: Do you accept elderly participants for this research endeavor?

Patients that are at least 18 months and no more than 89 years old can join this clinical trial.

Q: Are there any remaining slots for participants in this experiment?

This clinical trial is no longer recruiting participants, as reported on the official website. It was initially published in December of 2024 and last amended a year prior. However, there are currently 1241 other studies actively seeking enrolment from volunteers.

Phase < 1

Waitlist Available

Led By Jonathan McConathy, MD, PhD

Research Sponsored by University of Alabama at Birmingham

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

18 years of age or older at the time of enrollment

Timeline

Screening 3 weeks

Treatment Varies

Follow Up from injection to 45 minutes, 2 hours, and 4 hours after pet agent administration.

Awards & highlights

Study Summary

This trial will test if a new imaging tech is safe and effective for imaging brain tumors. It will also explore if it can accurately distinguish tumors from radiation effects.

Who is the study for?

This trial is for adults over 18 with a life expectancy of more than 12 weeks. It includes healthy volunteers, those with high-grade glioma after radiation, and patients with brain metastases from other tumors. Women able to have children must test negative for pregnancy.Check my eligibility

What is being tested?

[F-18]MeFAMP PET imaging is being tested to see if it's safe and how well it can show primary and metastatic brain tumors. The study has three parts: one for healthy people, one for glioma patients, and another for those with brain metastases.See study design

What are the potential side effects?

Since this is the first time [F-18]MeFAMP PET is used in humans, part of the study aims to establish its safety profile. Potential side effects are not detailed but will be monitored throughout the trial.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am 18 years old or older.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ from injection to 45 minutes, 2 hours, and 4 hours after pet agent administration.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~from injection to 45 minutes, 2 hours, and 4 hours after pet agent administration.

This trial's timeline: 3 weeks for screening, Varies for treatment, and from injection to 45 minutes, 2 hours, and 4 hours after pet agent administration. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Human dosimetry for [F-18]MeFAMP.

Safety of [F-18]MeFAMP

Trial Design

3Treatment groups

Experimental Treatment

Group I: High Grade Glioma (cohort 2)Experimental Treatment1 Intervention

Recurrent high grade glioma after radiation therapy

Group II: Healthy Volunteers (cohort 1)Experimental Treatment1 Intervention

Whole Body Dosimetry for healthy volunteers

Group III: Brain Metastasis (cohort 3)Experimental Treatment1 Intervention

Brain metastases from extra-cranial solid tumors before and after radiation therapy

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of Alabama at BirminghamLead Sponsor

1,591 Previous Clinical Trials

2,281,637 Total Patients Enrolled

Jonathan McConathy, MD, PhDPrincipal InvestigatorUniversity of Alabama at Birmingham

5 Previous Clinical Trials

146 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What criteria must be met to qualify for enrollment in this experiment?

"To be eligible to join this trial, applicants must satisfy the criteria of being aged between 18 months and 89 years old with no pre-existing conditions. Aiming to recruit 28 volunteers in total."

Answered by AI

Do you accept elderly participants for this research endeavor?

"Patients that are at least 18 months and no more than 89 years old can join this clinical trial."

Answered by AI

Are there any remaining slots for participants in this experiment?

"This clinical trial is no longer recruiting participants, as reported on the official website. It was initially published in December of 2024 and last amended a year prior. However, there are currently 1241 other studies actively seeking enrolment from volunteers."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors

Jonathan E McConathy 2024. "MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05676489.

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