Cafe Move for Preventing Frailty in Aging

Overseen By Brian J Loyd

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: University of Montana

Disqualifiers: Not legally autonomous, Institutionalized

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

36 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores a new method to maintain health and prevent frailty as people age. It focuses on helping older adults manage their physical health independently. The treatment, called Cafe Move, is a program designed to encourage physical activity by removing barriers to staying active. Individuals who live independently, can legally consent, and can sit, stand, and walk without assistance may qualify. As an unphased trial, participation offers a unique opportunity to contribute to innovative research that could enhance healthy aging for many.

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that Cafe Move is safe for preventing frailty in aging?

Research is examining Cafe Move as a method to help older adults avoid physical frailty, aiming to maintain health and independence. A previous study assessed how well people tolerate Cafe Move, focusing on any uncomfortable side effects. Results so far indicate that participants tolerate it well. No major negative effects have emerged in the reviewed studies, which is promising for safety. However, as research continues, staying updated with new information is important. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about Cafe Move because it takes a novel approach to preventing frailty in aging by focusing on lifestyle and physical activity rather than medication. While traditional treatments for frailty often involve medications or dietary supplements, Cafe Move emphasizes structured physical movement and social interaction, potentially offering a holistic and sustainable way to enhance physical resilience. This non-pharmacological strategy is especially appealing because it might reduce the reliance on medications and their associated side effects, making it a safe and accessible option for older adults.

What evidence suggests that Cafe Move is effective for preventing frailty in aging?

Research has shown that group exercise programs, like Cafe Move, benefit frail older adults more than exercising alone at home. One study found that participants who engaged in specific physical exercises improved their frailty. After 18 months, 12.3% of those in the exercise group were no longer considered frail, compared to just 2% in the non-exercise group. Programs incorporating various types of exercise have greatly improved frailty. This suggests that Cafe Move's group exercise approach could effectively prevent or reduce frailty in older adults. ^{1 2 3 6 7}

Are You a Good Fit for This Trial?

This trial is for individuals who can legally make their own decisions, live on their own, and can sit, stand, and walk without help. It's not open to those who aren't able to consent for themselves or are living in an institution.

Inclusion Criteria

I am legally able to make my own health decisions.

I can sit, stand, and walk by myself.

I live on my own without needing daily help.

Exclusion Criteria

Institutionalized

I am not legally able to give consent by myself.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Control Phase

Participants' health behaviors and engagement with preventive health offerings are monitored via periodic phone surveys

3 months

Periodic phone surveys

Intervention Phase

Café Move is made available to participants, and their health behaviors and engagement with preventive health offerings are monitored

3 months

Periodic phone surveys

Follow-up

Participants are monitored for safety and effectiveness after the intervention

4-6 months

What Are the Treatments Tested in This Trial?

Interventions

• Cafe Move

Trial Overview The study is looking at a new program called Cafe Move aimed at preventing physical frailty as people get older. The program focuses on making it easier for people to access health resources and manage their physical well-being independently.

Who Is Running the Clinical Trial?

University of Montana

Lead Sponsor

Trials

29

Recruited

4,700+

Published Research Related to This Trial

A study of 1,188 community-dwelling elderly individuals in Detroit identified four patterns of outdoor mobility over 15 months, highlighting that many older adults experience low or declining outdoor activity.

Key risk factors for limited mobility included older age, severe mobility impairment, fear of falling, and physical barriers at home, indicating that both health status and environmental factors significantly impact outdoor mobility in frail elderly individuals.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Trajectories of Outdoor Mobility in Vulnerable Community-Dwelling Elderly: The Role of Individual and Environmental Factors. Smith, AR., Chen, C., Clarke, P., et al.[2017]

The FOCUS project developed guidelines recommending physical activity and nutritional interventions, tailored care, and cognitive training to prevent or reverse age-related frailty, based on a review of quantitative and qualitative studies.

Despite these recommendations, the panel noted that the evidence was limited and of heterogeneous quality, leading to weak (provisional) recommendations and highlighting the need for further high-quality research in this area.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Interventions to prevent, delay or reverse frailty in older people: a journey towards clinical guidelines. Marcucci, M., Damanti, S., Germini, F., et al.[2020]

A study involving 163 participants aged 55 and older found that daily walking speed (DWS) measured through a smartphone app is associated with frailty, with slower speeds observed in frail individuals compared to those who are robust or prefrail.

The frailty group exhibited significantly shorter step lengths, indicating that both DWS and step length can be useful indicators for assessing frailty in older adults.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Association between daily life walking speed and frailty measured by a smartphone application: a cross-sectional study. Kawai, H., Obuchi, S., Ejiri, M., et al.[2023]

The SAFE study involved co-designing quality improvement initiatives with public and patient representatives to enhance care for frail older patients in hospitals, focusing on five priority areas such as improved mobility and access to food and hydration.

Key outcomes from the co-design process emphasized the importance of patient-centered care, including dignity and respectful communication, which are essential for effective healthcare delivery to frail older individuals.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Enabling public, patient and practitioner involvement in co-designing frailty pathways in the acute care setting. O'Donnell, D., Ní Shé, É., McCarthy, M., et al.[2023]

A study involving 319 pre-frail or frail older adults showed that individualized home-based exercise and nutrition interventions significantly improved frailty scores after 6 months, with the combination group showing the greatest improvement.

Participants in the exercise, nutrition, and combination groups also experienced notable enhancements in physical performance and mental health, indicating that these interventions can effectively support overall well-being in older adults.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Individualized home-based exercise and nutrition interventions improve frailty in older adults: a randomized controlled trial. Hsieh, TJ., Su, SC., Chen, CW., et al.[2020]

The ADVANTAGE Joint Action, cofinanced by the European Commission and 22 Member States from 2017-2019, successfully developed a common strategy to address frailty in older adults, emphasizing healthy aging as a public health priority across diverse European countries.

The initiative created effective multisectoral networks and practical routes for preventing frailty and dependency, demonstrating that such collaborative actions can be replicated in other regions, including Latin America and the Caribbean, to promote healthy aging.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

[The European ADVANTAGE experience for management of frailty: keys to its applicability in Latin AmericaA experiência europeia ADVANTAGE para manejo da fragilidade: apontamentos para sua aplicabilidade na América Latina]. Alonso Bouzón, C., Rodríguez Mañas, L.[2021]

The +AGIL Barcelona program aims to combat frailty in older adults through a community-based, multi-component intervention, involving 185 participants with an average age of 81.6 years, highlighting the need for flexible and adaptable strategies in managing frailty.

Early findings suggest that despite being independent in daily activities, participants exhibited clear signs of frailty, indicating that targeted interventions can be crucial for improving physical function and overall health outcomes in this population.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Integrated primary and geriatric care for frail older adults in the community: Implementation of a complex intervention into real life. Inzitari, M., Pérez, LM., Enfedaque, MB., et al.[2019]

Training interventions are the most effective way to improve health outcomes in frail older adults, according to several systematic reviews and meta-analyses.

Group exercise programs are more beneficial than home-based exercise for frail individuals, highlighting the need for expanded access to group training opportunities for this population.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

[Diagnosis of frailty as starting point for training interventions]. Benzinger, P., Rapp, K., Bauer, J.[2022]

Increasing physical activity through mobility training can significantly reduce frailty in older adults, leading to better health outcomes.

Mobility is crucial for maintaining independence and well-being in older adults, highlighting the importance of targeted interventions in community settings.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Effectiveness of mobility training for frail older adults living in the community. Harrison, J., Phoong, KY., Mansoor, M., et al.[2023]

In a study of 252 community-dwelling adults aged 50-80, it was found that older participants (70 and above) were significantly more likely to be in the action or maintenance stages of planning for aging and frailty, particularly in financial aspects.

The majority of participants reported having more experiences with planning for others rather than themselves, highlighting a potential gap in personal readiness for aging that could be addressed in future interventions.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

PLAN: Preparing and Living for Aging Now; A descriptive study investigating older adults' readiness to plan for aging and frailty. Frechman, E., Dietrich, MS., Buck, HG., et al.[2022]

Citations

1. withpower.com withpower.com/trial/phase-frailty-2-2023-c2da8

Cafe Move for Preventing Frailty in Aging Cafe Move is unique because it focuses on group exercise interventions, which have been found to be more effective than home-based exercises for frail older ...

2. trialx.com trialx.com/clinical-trials/listings/220732/preliminary-testing-of-cafe-move-for-primary-prevention-of-physical-frailty/

Preliminary Testing of Cafe Move for Primary Prevention ... This study will examine the safety, feasibility, acceptability, and preliminary efficacy of Café Move. Briefly, we will make Café Move available ...

3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC12524544/

Targeted Physical Function Exercises for Frailty and Falls ... By 18 months, frailty status improved in the IG, with 12.3% classified as non-frail compared to 2.0% in the CG, while 14.5% of the CG ...

4. sciencedirect.com sciencedirect.com/science/article/abs/pii/S0167494325002031

Review Effectiveness of interventions to improve frailty ... Multimodal interventions effectively improved frailty in older adults. · Multicomponent exercise showed benefits; single-component was less effective. · Nutrition ...

5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC5771690/

Effectiveness of interventions to prevent pre-frailty and frailty ... To summarize the best available evidence regarding the effectiveness of interventions for preventing frailty progression in older adults.

6. frontiersin.org frontiersin.org/journals/public-health/articles/10.3389/fpubh.2023.1062843/full

Co-designing implementation strategies to promote remote ... This article is part of the Research Topic Novel Indicators and Strategies for Prevention and Management of Physical and Cognitive Frailty in Aging Population

7. sciencedirect.com sciencedirect.com/science/article/pii/S2260134124003773

Is frailty associated with increased concerns about falling ... This review identifies strong associations between increasing frailty and both CaF and associated activity restriction.