Axiron

Orchitis, Puberty, Delayed, Gonadotrophin releasing hormone deficiency + 9 more

Treatment

17 FDA approvals

3 Active Studies for Axiron

What is Axiron

Testosterone

The Generic name of this drug

Treatment Summary

Testosterone is a hormone that plays an important role in male sexual development. It is used to treat low levels of testosterone in the body, either due to primary hypogonadism or hypogonadotropic hypogonadism. Testosterone works by changing the way genes are expressed, causing the growth and development of masculine sex organs and other male characteristics. It was first isolated from samples in 1935 and has been synthetically created since then.

Androderm

is the brand name

image of different drug pills on a surface

Axiron Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Androderm

Testosterone

1995

90

Approved as Treatment by the FDA

Testosterone, commonly known as Androderm, is approved by the FDA for 17 uses including Spermatic Cord Torsion and Puberty, Delayed .

Spermatic Cord Torsion

Helps manage Torsion of testis

Puberty, Delayed

Used to treat Puberty, Delayed in combination with Testosterone enanthate

Hypogonadism

Helps manage Hypergonadotropic Hypogonadism

Breast

Used to treat inoperable, metastatic Breast cancer in combination with Testosterone enanthate

Torsion of testis

Helps manage Torsion of testis

Hypothalamo-pituitary disorder

Helps manage Hypothalamo-pituitary disorder

Delayed Puberty

Used to treat Puberty, Delayed in combination with Testosterone enanthate

Orchitis

Helps manage Orchitis

Orchitis

Helps manage Orchitis

Hypergonadotropic Hypogonadism

Helps manage Hypergonadotropic Hypogonadism

Hypogonadotropic hypogonadism

Gonadotrophin releasing hormone deficiency

Helps manage Gonadotrophin releasing hormone deficiency

1 to 5 years post-menopausal

Used to treat 1 to 5 years post-menopausal in combination with Testosterone enanthate

Anorchia

Helps manage vanishing testis syndrome

Orchidectomy

Helps manage Orchidectomy

inoperable, metastatic Breast cancer

Used to treat inoperable, metastatic Breast cancer in combination with Testosterone enanthate

Hypogonadism

Helps manage Idiopathic Hypogonadotropic Hypogonadism

Effectiveness

How Axiron Affects Patients

Testosterone is used to help the body grow and develop masculine sex organs and features. It usually only works for a short amount of time (10 to 100 minutes) with normal levels of testosterone in an adult man ranging from 300 to 1000ng/dL. It is important to warn patients about the possible risks of exposing children to testosterone.

How Axiron works in the body

The androgen receptor helps the body develop masculine physical traits and characteristics. It is found in the cytoplasm and binds to testosterone and its active metabolite dihydrotestosterone (DHT). This binding causes the receptor to change shape, so it can travel to the nucleus of the cell. Here, it binds to DNA and triggers the production of specific genes. These genes are responsible for the development of masculine sex organs like the prostate and penis, as well as secondary sexual characteristics like facial hair and changes in muscle and fat distribution.

When to interrupt dosage

The prescribed amount of Axiron is based on the diagnosed condition, including Gonadotrophin releasing hormone deficiency, Orchidectomy and Orchitis. The amount of dosage is dependent on the technique of administration featured in the table beneath.

Condition

Dosage

Administration

Breast

, 0.01 mg/mg, 0.05 mg/mg, 75.0 mg, 100.0 mg/mL, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 200.0 mg/mL, 30.0 mg/mL, 30.0 mg, 100.0 mg, 200.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 87.5 mg, 40.0 mg, 1.0 %, 4.5 %, 0.03 mg/hour, 5.5 mg, 0.1 mg/mg, 250.0 mg/mL, 0.0125 mg/mg, 12.5 mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 0.00162 mg/mg, 0.02025 mg/mg, 0.0405 mg/mg, 30.0 mg/pump actuation, 12.5 mg/pump actuation, 60.0 mg

, Transdermal, Gel - Transdermal, Gel, Injection, solution - Intramuscular, Intramuscular, Gel - Topical, Topical, Subcutaneous, Pellet - Subcutaneous, Pellet, Solution, Solution - Topical, Tablet, Buccal, Pellet - Oral, Oral, Capsule, Capsule - Oral, Gel - Nasal, Patch - Transdermal, Nasal, Gel, metered - Topical, Gel, metered, Patch, Solution - Transdermal, Gel, metered - Nasal, Gel, metered - Transdermal, Pellet, implantable - Subcutaneous, Pellet, implantable, Pellet, implantable - Parenteral, Parenteral, Injection - Intramuscular, Tablet - Buccal, Suspension, Suspension - Intramuscular

Orchitis

, 0.01 mg/mg, 0.05 mg/mg, 75.0 mg, 100.0 mg/mL, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 200.0 mg/mL, 30.0 mg/mL, 30.0 mg, 100.0 mg, 200.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 87.5 mg, 40.0 mg, 1.0 %, 4.5 %, 0.03 mg/hour, 5.5 mg, 0.1 mg/mg, 250.0 mg/mL, 0.0125 mg/mg, 12.5 mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 0.00162 mg/mg, 0.02025 mg/mg, 0.0405 mg/mg, 30.0 mg/pump actuation, 12.5 mg/pump actuation, 60.0 mg

, Transdermal, Gel - Transdermal, Gel, Injection, solution - Intramuscular, Intramuscular, Gel - Topical, Topical, Subcutaneous, Pellet - Subcutaneous, Pellet, Solution, Solution - Topical, Tablet, Buccal, Pellet - Oral, Oral, Capsule, Capsule - Oral, Gel - Nasal, Patch - Transdermal, Nasal, Gel, metered - Topical, Gel, metered, Patch, Solution - Transdermal, Gel, metered - Nasal, Gel, metered - Transdermal, Pellet, implantable - Subcutaneous, Pellet, implantable, Pellet, implantable - Parenteral, Parenteral, Injection - Intramuscular, Tablet - Buccal, Suspension, Suspension - Intramuscular

Puberty, Delayed

, 0.01 mg/mg, 0.05 mg/mg, 75.0 mg, 100.0 mg/mL, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 200.0 mg/mL, 30.0 mg/mL, 30.0 mg, 100.0 mg, 200.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 87.5 mg, 40.0 mg, 1.0 %, 4.5 %, 0.03 mg/hour, 5.5 mg, 0.1 mg/mg, 250.0 mg/mL, 0.0125 mg/mg, 12.5 mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 0.00162 mg/mg, 0.02025 mg/mg, 0.0405 mg/mg, 30.0 mg/pump actuation, 12.5 mg/pump actuation, 60.0 mg

, Transdermal, Gel - Transdermal, Gel, Injection, solution - Intramuscular, Intramuscular, Gel - Topical, Topical, Subcutaneous, Pellet - Subcutaneous, Pellet, Solution, Solution - Topical, Tablet, Buccal, Pellet - Oral, Oral, Capsule, Capsule - Oral, Gel - Nasal, Patch - Transdermal, Nasal, Gel, metered - Topical, Gel, metered, Patch, Solution - Transdermal, Gel, metered - Nasal, Gel, metered - Transdermal, Pellet, implantable - Subcutaneous, Pellet, implantable, Pellet, implantable - Parenteral, Parenteral, Injection - Intramuscular, Tablet - Buccal, Suspension, Suspension - Intramuscular

Gonadotrophin releasing hormone deficiency

, 0.01 mg/mg, 0.05 mg/mg, 75.0 mg, 100.0 mg/mL, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 200.0 mg/mL, 30.0 mg/mL, 30.0 mg, 100.0 mg, 200.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 87.5 mg, 40.0 mg, 1.0 %, 4.5 %, 0.03 mg/hour, 5.5 mg, 0.1 mg/mg, 250.0 mg/mL, 0.0125 mg/mg, 12.5 mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 0.00162 mg/mg, 0.02025 mg/mg, 0.0405 mg/mg, 30.0 mg/pump actuation, 12.5 mg/pump actuation, 60.0 mg

, Transdermal, Gel - Transdermal, Gel, Injection, solution - Intramuscular, Intramuscular, Gel - Topical, Topical, Subcutaneous, Pellet - Subcutaneous, Pellet, Solution, Solution - Topical, Tablet, Buccal, Pellet - Oral, Oral, Capsule, Capsule - Oral, Gel - Nasal, Patch - Transdermal, Nasal, Gel, metered - Topical, Gel, metered, Patch, Solution - Transdermal, Gel, metered - Nasal, Gel, metered - Transdermal, Pellet, implantable - Subcutaneous, Pellet, implantable, Pellet, implantable - Parenteral, Parenteral, Injection - Intramuscular, Tablet - Buccal, Suspension, Suspension - Intramuscular

1 to 5 years post-menopausal

, 0.01 mg/mg, 0.05 mg/mg, 75.0 mg, 100.0 mg/mL, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 200.0 mg/mL, 30.0 mg/mL, 30.0 mg, 100.0 mg, 200.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 87.5 mg, 40.0 mg, 1.0 %, 4.5 %, 0.03 mg/hour, 5.5 mg, 0.1 mg/mg, 250.0 mg/mL, 0.0125 mg/mg, 12.5 mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 0.00162 mg/mg, 0.02025 mg/mg, 0.0405 mg/mg, 30.0 mg/pump actuation, 12.5 mg/pump actuation, 60.0 mg

, Transdermal, Gel - Transdermal, Gel, Injection, solution - Intramuscular, Intramuscular, Gel - Topical, Topical, Subcutaneous, Pellet - Subcutaneous, Pellet, Solution, Solution - Topical, Tablet, Buccal, Pellet - Oral, Oral, Capsule, Capsule - Oral, Gel - Nasal, Patch - Transdermal, Nasal, Gel, metered - Topical, Gel, metered, Patch, Solution - Transdermal, Gel, metered - Nasal, Gel, metered - Transdermal, Pellet, implantable - Subcutaneous, Pellet, implantable, Pellet, implantable - Parenteral, Parenteral, Injection - Intramuscular, Tablet - Buccal, Suspension, Suspension - Intramuscular

Hypothalamo-pituitary disorder

, 0.01 mg/mg, 0.05 mg/mg, 75.0 mg, 100.0 mg/mL, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 200.0 mg/mL, 30.0 mg/mL, 30.0 mg, 100.0 mg, 200.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 87.5 mg, 40.0 mg, 1.0 %, 4.5 %, 0.03 mg/hour, 5.5 mg, 0.1 mg/mg, 250.0 mg/mL, 0.0125 mg/mg, 12.5 mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 0.00162 mg/mg, 0.02025 mg/mg, 0.0405 mg/mg, 30.0 mg/pump actuation, 12.5 mg/pump actuation, 60.0 mg

, Transdermal, Gel - Transdermal, Gel, Injection, solution - Intramuscular, Intramuscular, Gel - Topical, Topical, Subcutaneous, Pellet - Subcutaneous, Pellet, Solution, Solution - Topical, Tablet, Buccal, Pellet - Oral, Oral, Capsule, Capsule - Oral, Gel - Nasal, Patch - Transdermal, Nasal, Gel, metered - Topical, Gel, metered, Patch, Solution - Transdermal, Gel, metered - Nasal, Gel, metered - Transdermal, Pellet, implantable - Subcutaneous, Pellet, implantable, Pellet, implantable - Parenteral, Parenteral, Injection - Intramuscular, Tablet - Buccal, Suspension, Suspension - Intramuscular

Orchidectomy

, 0.01 mg/mg, 0.05 mg/mg, 75.0 mg, 100.0 mg/mL, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 200.0 mg/mL, 30.0 mg/mL, 30.0 mg, 100.0 mg, 200.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 87.5 mg, 40.0 mg, 1.0 %, 4.5 %, 0.03 mg/hour, 5.5 mg, 0.1 mg/mg, 250.0 mg/mL, 0.0125 mg/mg, 12.5 mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 0.00162 mg/mg, 0.02025 mg/mg, 0.0405 mg/mg, 30.0 mg/pump actuation, 12.5 mg/pump actuation, 60.0 mg

, Transdermal, Gel - Transdermal, Gel, Injection, solution - Intramuscular, Intramuscular, Gel - Topical, Topical, Subcutaneous, Pellet - Subcutaneous, Pellet, Solution, Solution - Topical, Tablet, Buccal, Pellet - Oral, Oral, Capsule, Capsule - Oral, Gel - Nasal, Patch - Transdermal, Nasal, Gel, metered - Topical, Gel, metered, Patch, Solution - Transdermal, Gel, metered - Nasal, Gel, metered - Transdermal, Pellet, implantable - Subcutaneous, Pellet, implantable, Pellet, implantable - Parenteral, Parenteral, Injection - Intramuscular, Tablet - Buccal, Suspension, Suspension - Intramuscular

Spermatic Cord Torsion

, 0.01 mg/mg, 0.05 mg/mg, 75.0 mg, 100.0 mg/mL, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 200.0 mg/mL, 30.0 mg/mL, 30.0 mg, 100.0 mg, 200.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 87.5 mg, 40.0 mg, 1.0 %, 4.5 %, 0.03 mg/hour, 5.5 mg, 0.1 mg/mg, 250.0 mg/mL, 0.0125 mg/mg, 12.5 mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 0.00162 mg/mg, 0.02025 mg/mg, 0.0405 mg/mg, 30.0 mg/pump actuation, 12.5 mg/pump actuation, 60.0 mg

, Transdermal, Gel - Transdermal, Gel, Injection, solution - Intramuscular, Intramuscular, Gel - Topical, Topical, Subcutaneous, Pellet - Subcutaneous, Pellet, Solution, Solution - Topical, Tablet, Buccal, Pellet - Oral, Oral, Capsule, Capsule - Oral, Gel - Nasal, Patch - Transdermal, Nasal, Gel, metered - Topical, Gel, metered, Patch, Solution - Transdermal, Gel, metered - Nasal, Gel, metered - Transdermal, Pellet, implantable - Subcutaneous, Pellet, implantable, Pellet, implantable - Parenteral, Parenteral, Injection - Intramuscular, Tablet - Buccal, Suspension, Suspension - Intramuscular

Hypogonadism

, 0.01 mg/mg, 0.05 mg/mg, 75.0 mg, 100.0 mg/mL, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 200.0 mg/mL, 30.0 mg/mL, 30.0 mg, 100.0 mg, 200.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 87.5 mg, 40.0 mg, 1.0 %, 4.5 %, 0.03 mg/hour, 5.5 mg, 0.1 mg/mg, 250.0 mg/mL, 0.0125 mg/mg, 12.5 mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 0.00162 mg/mg, 0.02025 mg/mg, 0.0405 mg/mg, 30.0 mg/pump actuation, 12.5 mg/pump actuation, 60.0 mg

, Transdermal, Gel - Transdermal, Gel, Injection, solution - Intramuscular, Intramuscular, Gel - Topical, Topical, Subcutaneous, Pellet - Subcutaneous, Pellet, Solution, Solution - Topical, Tablet, Buccal, Pellet - Oral, Oral, Capsule, Capsule - Oral, Gel - Nasal, Patch - Transdermal, Nasal, Gel, metered - Topical, Gel, metered, Patch, Solution - Transdermal, Gel, metered - Nasal, Gel, metered - Transdermal, Pellet, implantable - Subcutaneous, Pellet, implantable, Pellet, implantable - Parenteral, Parenteral, Injection - Intramuscular, Tablet - Buccal, Suspension, Suspension - Intramuscular

Hypogonadotropic hypogonadism

, 0.01 mg/mg, 0.05 mg/mg, 75.0 mg, 100.0 mg/mL, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 200.0 mg/mL, 30.0 mg/mL, 30.0 mg, 100.0 mg, 200.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 87.5 mg, 40.0 mg, 1.0 %, 4.5 %, 0.03 mg/hour, 5.5 mg, 0.1 mg/mg, 250.0 mg/mL, 0.0125 mg/mg, 12.5 mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 0.00162 mg/mg, 0.02025 mg/mg, 0.0405 mg/mg, 30.0 mg/pump actuation, 12.5 mg/pump actuation, 60.0 mg

, Transdermal, Gel - Transdermal, Gel, Injection, solution - Intramuscular, Intramuscular, Gel - Topical, Topical, Subcutaneous, Pellet - Subcutaneous, Pellet, Solution, Solution - Topical, Tablet, Buccal, Pellet - Oral, Oral, Capsule, Capsule - Oral, Gel - Nasal, Patch - Transdermal, Nasal, Gel, metered - Topical, Gel, metered, Patch, Solution - Transdermal, Gel, metered - Nasal, Gel, metered - Transdermal, Pellet, implantable - Subcutaneous, Pellet, implantable, Pellet, implantable - Parenteral, Parenteral, Injection - Intramuscular, Tablet - Buccal, Suspension, Suspension - Intramuscular

Anorchia

, 0.01 mg/mg, 0.05 mg/mg, 75.0 mg, 100.0 mg/mL, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 200.0 mg/mL, 30.0 mg/mL, 30.0 mg, 100.0 mg, 200.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 87.5 mg, 40.0 mg, 1.0 %, 4.5 %, 0.03 mg/hour, 5.5 mg, 0.1 mg/mg, 250.0 mg/mL, 0.0125 mg/mg, 12.5 mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 0.00162 mg/mg, 0.02025 mg/mg, 0.0405 mg/mg, 30.0 mg/pump actuation, 12.5 mg/pump actuation, 60.0 mg

, Transdermal, Gel - Transdermal, Gel, Injection, solution - Intramuscular, Intramuscular, Gel - Topical, Topical, Subcutaneous, Pellet - Subcutaneous, Pellet, Solution, Solution - Topical, Tablet, Buccal, Pellet - Oral, Oral, Capsule, Capsule - Oral, Gel - Nasal, Patch - Transdermal, Nasal, Gel, metered - Topical, Gel, metered, Patch, Solution - Transdermal, Gel, metered - Nasal, Gel, metered - Transdermal, Pellet, implantable - Subcutaneous, Pellet, implantable, Pellet, implantable - Parenteral, Parenteral, Injection - Intramuscular, Tablet - Buccal, Suspension, Suspension - Intramuscular

Hypogonadism

, 0.01 mg/mg, 0.05 mg/mg, 75.0 mg, 100.0 mg/mL, 0.0162 mg/mg, 0.2 mg/hour, 0.4 mg/hour, 200.0 mg/mL, 30.0 mg/mL, 30.0 mg, 100.0 mg, 200.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 87.5 mg, 40.0 mg, 1.0 %, 4.5 %, 0.03 mg/hour, 5.5 mg, 0.1 mg/mg, 250.0 mg/mL, 0.0125 mg/mg, 12.5 mg, 12.2 mg, 24.3 mg, 0.025 mg/mg, 0.25 mg/hour, 0.5 mg/hour, 0.055 mg/mg, 0.00162 mg/mg, 0.02025 mg/mg, 0.0405 mg/mg, 30.0 mg/pump actuation, 12.5 mg/pump actuation, 60.0 mg

, Transdermal, Gel - Transdermal, Gel, Injection, solution - Intramuscular, Intramuscular, Gel - Topical, Topical, Subcutaneous, Pellet - Subcutaneous, Pellet, Solution, Solution - Topical, Tablet, Buccal, Pellet - Oral, Oral, Capsule, Capsule - Oral, Gel - Nasal, Patch - Transdermal, Nasal, Gel, metered - Topical, Gel, metered, Patch, Solution - Transdermal, Gel, metered - Nasal, Gel, metered - Transdermal, Pellet, implantable - Subcutaneous, Pellet, implantable, Pellet, implantable - Parenteral, Parenteral, Injection - Intramuscular, Tablet - Buccal, Suspension, Suspension - Intramuscular

Warnings

Axiron Contraindications

Condition

Risk Level

Notes

suspected pregnancy

Do Not Combine

Breast Cancer

Do Not Combine

There are 20 known major drug interactions with Axiron.

Common Axiron Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Testosterone.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be increased when combined with Testosterone.

Alectinib

Major

The metabolism of Alectinib can be increased when combined with Testosterone.

Aminophylline

Major

The metabolism of Aminophylline can be increased when combined with Testosterone.

Astemizole

Major

The metabolism of Astemizole can be increased when combined with Testosterone.

Axiron Toxicity & Overdose Risk

Information about an overdose of a testosterone product is not readily available. However, if someone overdoses on the injectable form of the drug, they may suffer a stroke. To treat an overdose of testosterone, the product should be stopped and any topical product washed off with soap and water. The patient should also receive symptomatic and supportive treatments.

image of a doctor in a lab doing drug, clinical research

Axiron Novel Uses: Which Conditions Have a Clinical Trial Featuring Axiron?

A total of 10 active clinical trials are exploring the potential of Axiron to treat Orchitis, Torsion of Testis and Hypothalamic-Pituitary Disorders.

Condition

Clinical Trials

Trial Phases

Hypothalamo-pituitary disorder

0 Actively Recruiting

1 to 5 years post-menopausal

0 Actively Recruiting

Hypogonadism

0 Actively Recruiting

Orchitis

0 Actively Recruiting

Spermatic Cord Torsion

0 Actively Recruiting

Orchidectomy

0 Actively Recruiting

Breast

0 Actively Recruiting

Hypogonadotropic hypogonadism

0 Actively Recruiting

Puberty, Delayed

0 Actively Recruiting

Gonadotrophin releasing hormone deficiency

0 Actively Recruiting

Anorchia

0 Actively Recruiting

Hypogonadism

3 Actively Recruiting

Phase 2

Axiron Reviews: What are patients saying about Axiron?

4

Patient Review

8/16/2013

Axiron for Pituitary Hormone Deficiency

2

Patient Review

1/7/2014

Axiron for Absence of Testicles

I'm not convinced that this treatment is worth the high price tag. It did improve my symptoms slightly, but caused some skin irritation.

1.7

Patient Review

11/11/2015

Axiron for Absence of Testicles

The application is terrible: pump it into a "cup" and hope it doesn't slosh out while trying to slather it into your armpit, where it starts running down your sides because it takes too long to dry. Stuck it out for a month, progressively bad psychosis, was suicidal by the end. Not ideal for guys who are on total testosterone replacement.

1.3

Patient Review

6/10/2016

Axiron for Deficient Activity of the Testis

I started using this treatment three months ago in order to improve my libido, which was a symptom of hypogonadism. I saw no improvement whatsoever and found the application process to be really painful and irritating. I'll be switching to injections as soon as possible.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about axiron

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Axiron a steroid?

"These drugs are anabolic steroids and they can cause harmful physical and psychological effects, especially for women. Women who are exposed to testosterone treatments may develop acne and masculinized characteristics, such as increased body and facial hair."

Answered by AI

Is Axiron still available?

"The FDA has announced that Axiron will no longer be manufactured, effective September 2017. The product is being discontinued for reasons unrelated to safety or efficacy."

Answered by AI

What is the generic name for Axiron?

"Assuming you are asking for a summary:

Testosterone is a drug used in males to treat low testosterone levels. It is available in gel, cream, andpatch forms. Testosterone levels are typically measured via blood tests."

Answered by AI

What is Axiron used for?

"Axiron is a drug used to treat the symptoms of Testosterone Deficiency. It may be used alone or with other medications."

Answered by AI

Clinical Trials for Axiron

Image of ReproNovo Investigational Site in Garden City, United States.

Leflutrozole for Hypogonadotropic Hypogonadism

18 - 49
Male
Garden City, NY

The goal of this clinical trial is to evaluate three doses of the drug leflutrozole on improvement of semen quality in men with hypogonadotropic hypogonadism, a condition that affects hormone levels and fertility. It will also study the safety of leflutrozole. The main questions it aims to answer are: * Does leflutrozole improve semen quality? * What medical problems do participants experience when taking leflutrozole? Researchers will compare leflutrozole to a placebo (a look-alike substance that contains no drug). Participants will: * Take leflutrozole or a placebo orally once a week for 16 weeks. * Visit the clinic every 4 weeks for checkups and tests. * Provide semen samples to measure changes in semen quality. * Have their blood tested to measure hormone levels and ensure safety. * Be monitored for any side effects.

Phase 2
Recruiting

ReproNovo Investigational Site (+2 Sites)

Medical Director

ReproNovo Aps