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Brachytherapy

Image-Guided Brachytherapy for Gynecologic Cancers

Q: Is this research project open to individuals aged fifty-five and above?

This study only allows participants that are between 18 and 100 years old, as declared within the inclusion criteria.

Q: What is the current enrollment size of this medical experiment?

Indeed, clinicaltrials.gov displays that this trial is actively recruiting participants who fit the eligibility criteria. The trial was initially posted on December 15th 2016 and has recently been updated on October 11th 2022; 54 patients must be enrolled from 2 sites.

Q: Is there an open call for participants in this trial?

According to the clinicaltrials.gov database, this study is currently recruiting and has been since December 15th 2016. The information was most recently updated on October 11th 2022.

Q: Would I be eligible to join this clinical trial?

This research requires 54 patients aged 18 and over with vaginal cancers to participate. The set of criteria for these applicants is as follows: having exceeded the age of majority, being likely to survive more than 6 months, displaying a diagnosis-defined site/stage status, potentially receiving prior radiation or chemotherapy treatments depending on their doctor's judgement call and finally showcasing carcinomas within their urethra at the discretion of physicians involved in care.

N/A

Recruiting

Led By Akila Viswanathan, M.D.

Research Sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Carcinoma of the cervix: Stage I-IVA or vaginal recurrence

Carcinoma of the uterus: Stage IIIB (vaginal involvement), inoperable, or vaginal recurrence

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 year and 2 year

Awards & highlights

Study Summary

This trial is testing whether magnetic resonance imaging-guided therapy (MRT) is a better treatment for gynecologic cancers than the routinely used CT scan.

Who is the study for?

This trial is for adults over 18 with various gynecologic cancers (vulvar, vaginal, bladder, uterine, cervical) who are eligible for internal radiation therapy. They must have a life expectancy of more than 6 months and be physically able to participate (ECOG <2). Prior treatments like radiation or chemotherapy are allowed. Exclusions include severe illnesses that could affect study participation or having metal in the head/eyes.Check my eligibility

What is being tested?

The trial tests if MRI can guide brachytherapy applicator placement better than CT scans for treating gynecologic cancers. It aims to see if MRI improves tumor assessment during treatment and helps reduce unnecessary radiation exposure to the body.See study design

What are the potential side effects?

While specific side effects aren't listed here, brachytherapy generally may cause localized pain, swelling or bruising at the treatment site, fatigue from radiation exposure and potential short-term changes in urinary or bowel habits.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

My cervical cancer is between Stage I and IVA, or I have a vaginal recurrence.

Select...

My uterine cancer is at stage IIIB, inoperable, or has recurred in the vagina.

Select...

My cancer is in the vagina and is between stages I-IVA or has come back.

Select...

I am older than 18 years.

Select...

My vulvar cancer is between Stage I and IVA or has come back.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 year and 2 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 year and 2 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year and 2 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Dosing changes

Secondary outcome measures

Rate of survival

The rate of treatment-related toxicity

Time to local failure

Trial Design

1Treatment groups

Experimental Treatment

Group I: Image-Guided BrachytherapyExperimental Treatment1 Intervention

Magnetic Resonance Imaging (MRI) guided brachytherapy Procedure: Image-Guided Brachytherapy

0 / 5Eligibility criteria met

Find a Location

Who is running the clinical trial?

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsLead Sponsor

558 Previous Clinical Trials

32,866 Total Patients Enrolled

National Cancer Institute (NCI)NIH

13,663 Previous Clinical Trials

40,925,851 Total Patients Enrolled

Akila Viswanathan, M.D.Principal InvestigatorJohns Hopkins Department of Radiation Oncology

Media Library

Image-Guided Brachytherapy (Brachytherapy) Clinical Trial Eligibility Overview. Trial Name: NCT02993900 — N/A

Cervical Cancer Research Study Groups: Image-Guided Brachytherapy

Cervical Cancer Clinical Trial 2023: Image-Guided Brachytherapy Highlights & Side Effects. Trial Name: NCT02993900 — N/A

Image-Guided Brachytherapy (Brachytherapy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02993900 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research project open to individuals aged fifty-five and above?

"This study only allows participants that are between 18 and 100 years old, as declared within the inclusion criteria."

Answered by AI

What is the current enrollment size of this medical experiment?

"Indeed, clinicaltrials.gov displays that this trial is actively recruiting participants who fit the eligibility criteria. The trial was initially posted on December 15th 2016 and has recently been updated on October 11th 2022; 54 patients must be enrolled from 2 sites."

Answered by AI

Is there an open call for participants in this trial?

"According to the clinicaltrials.gov database, this study is currently recruiting and has been since December 15th 2016. The information was most recently updated on October 11th 2022."

Answered by AI

Would I be eligible to join this clinical trial?

"This research requires 54 patients aged 18 and over with vaginal cancers to participate. The set of criteria for these applicants is as follows: having exceeded the age of majority, being likely to survive more than 6 months, displaying a diagnosis-defined site/stage status, potentially receiving prior radiation or chemotherapy treatments depending on their doctor's judgement call and finally showcasing carcinomas within their urethra at the discretion of physicians involved in care."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Image-Guided Gynecologic Brachytherapy

2016. "Image-Guided Gynecologic Brachytherapy". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02993900.

All > Cervical Cancer > Uterine Cancer