Image-Guided Brachytherapy for Cervical Cancer

Johns Hopkins, Baltimore, MD
Targeting 5 different conditionsImage-Guided BrachytherapyN/ARecruitingLed by Akila Viswanathan, M.D.Research Sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Study Summary

This trial is testing whether magnetic resonance imaging-guided therapy (MRT) is a better treatment for gynecologic cancers than the routinely used CT scan.

Eligible Conditions
  • Cervical Cancer
  • Vaginal Cancer
  • Bladder Cancer
  • Uterine Cancer
  • Vulvar Cancer

Eligibility Criteria

Inclusion Criteria

You will be eligible if you check “Yes” for the criteria below
You have cervical cancer that is in stage I to IV or has recurred in the vagina.
You have cancer in your vagina that is at stage I to IV or has come back in the vagina.
You have vulvar cancer that is in stage I to stage IVA, or it has come back after previous treatment.
You have advanced or recurring uterine cancer that cannot be treated with surgery.
Your doctor decides that you have urethral cancer.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year and 2 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year and 2 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Dosing changes
Secondary outcome measures
Rate of survival
The rate of treatment-related toxicity
Time to local failure

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Image-Guided BrachytherapyExperimental Treatment1 Intervention
Magnetic Resonance Imaging (MRI) guided brachytherapy Procedure: Image-Guided Brachytherapy

Find a site

Who is running the clinical trial?

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsLead Sponsor
546 Previous Clinical Trials
32,596 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,402 Previous Clinical Trials
41,225,287 Total Patients Enrolled
Akila Viswanathan, M.D.Principal Investigator
Johns Hopkins Department of Radiation Oncology

Media Library

Image-Guided Brachytherapy (Brachytherapy) Clinical Trial Eligibility Overview. Trial Name: NCT02993900 — N/A
Cervical Cancer Research Study Groups: Image-Guided Brachytherapy
Cervical Cancer Clinical Trial 2023: Image-Guided Brachytherapy Highlights & Side Effects. Trial Name: NCT02993900 — N/A
Image-Guided Brachytherapy (Brachytherapy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02993900 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research project open to individuals aged fifty-five and above?

"This study only allows participants that are between 18 and 100 years old, as declared within the inclusion criteria."

Answered by AI

What is the current enrollment size of this medical experiment?

"Indeed, displays that this trial is actively recruiting participants who fit the eligibility criteria. The trial was initially posted on December 15th 2016 and has recently been updated on October 11th 2022; 54 patients must be enrolled from 2 sites."

Answered by AI

Is there an open call for participants in this trial?

"According to the database, this study is currently recruiting and has been since December 15th 2016. The information was most recently updated on October 11th 2022."

Answered by AI

Would I be eligible to join this clinical trial?

"This research requires 54 patients aged 18 and over with vaginal cancers to participate. The set of criteria for these applicants is as follows: having exceeded the age of majority, being likely to survive more than 6 months, displaying a diagnosis-defined site/stage status, potentially receiving prior radiation or chemotherapy treatments depending on their doctor's judgement call and finally showcasing carcinomas within their urethra at the discretion of physicians involved in care."

Answered by AI
~13 spots leftby Dec 2025