HEIGHT RT for Prostate Cancer
This study is evaluating whether a higher dose of radiation may help control prostate cancer while reducing the amount of radiation to nearby organs.
See full descriptionAbout the trial for Prostate Cancer
Treatment Groups
This trial involves 2 different treatments. HEIGHT RT is the primary treatment being studied. Participants will be divided into 2 treatment groups. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
Eligibility
This trial is for male patients aged 18 and older. There are 10 eligibility criteria to participate in this trial as listed below.
Approximate Timelines
Measurement Requirements
This trial is evaluating whether HEIGHT RT will improve 1 primary outcome and 9 secondary outcomes in patients with Prostate Cancer. Measurement will happen over the course of 3 months post-RT, 9-months post-RT, within 3 months of 2-2.5 post-treatment biopsy.
Who is running the study
Principal InvestigatorPatient Q & A Section
What are common treatments for prostate cancer?
Treatment options for prostate cancer include surgery, radiation therapy and adjunctive medication. There are no studies investigating what the combination of treatments is best for patients. Treatment options should be tailored to the individual characteristics of each man.
How many people get prostate cancer a year in the United States?
It is estimated that there are approximately 518,000 men with a history of [prostate cancer](https://www.withpower.com/clinical-trials/prostate-cancer) among a population that is aged 40 and older. Given the number of new cancer diagnoses at each American state every year, these findings suggest that more than 1 in 5 men in the United States who now have prostate cancer do so annually. This is consistent with the incidence of prostate cancer observed in North American populations.
Can prostate cancer be cured?
Even with new, more effective treatment, prostate cancer cannot be cured. Nevertheless, even with advanced disease and/or low volume disease, a high degree of cure can be expected after successful therapy in certain high-risk patient groups.
What causes prostate cancer?
It has been found that there are several genetic and environmental risk factors that can be affected by obesity, but not all of the causes of [prostate cancer](https://www.withpower.com/clinical-trials/prostate-cancer) are known. Cancer.
What are the signs of prostate cancer?
The presence and characteristics of symptoms are the main determinants for PCa diagnosis even if the prostate tumor is small and is unlikely to cause any symptoms.
What is prostate cancer?
While there are many theories explaining what a [prostate cancer](https://www.withpower.com/clinical-trials/prostate-cancer) is, no one single theory is completely accepted. It is important to take into account that for prostate cancer there are no definitive treatment options. The first step in getting treatment is to diagnose the disease that has impacted the cancer patient. It is crucial to diagnose the cancer that is present as early as possible and to notify their doctors regarding the seriousness of the condition. Patients with prostate cancer have many options to treatment but none are permanent. Treatment for prostate cancer revolves around the quality of life that must be balanced with risks and burdens associated with treatment.
Does height rt improve quality of life for those with prostate cancer?
Height >190 cm improved the quality of life of the survivors for a mean of 8.2 months and 10.9 months for men with a height >185 cm and >190 cm, respectively. Height >190 cm was associated with a better quality of life for both the short term (p<0.0001) and long term.
Who should consider clinical trials for prostate cancer?
Clinical trials do not appear to be a viable option for most men with localized prostate cancer for whom surgical treatment is preferable, provided the disease status is good and a course of active surveillance is tolerated.
Has height rt proven to be more effective than a placebo?
Findings from a recent study of this study show no superiority of height (about 5 cm, compared with 4 cm of the conventional BPH treatment regimens) over a placebo to improve symptoms, HRQL, urinary parameters and prostate-specific antigen in a randomized controlled trial of men having BPH.
Have there been other clinical trials involving height rt?
We found only one other study on height and prostate cancer, including only 12 prostate cancer patients, with the group not receiving height treatment and no height outcome. This small trial found a significantly higher likelihood of early relapse for prostate cancer patients with height and therefore suggest that this may be related to height treatments. Nonetheless, as we only found two other studies, we cannot completely rule out a possible role of height treatment and prostate cancer.
What are the common side effects of height rt?
Height rt is associated with side effects in pediatric patients, but as in adults most are of minor clinical importance. On the other hand, short stature is associated with increased risk of thyroid and osteoporotic fractures.
How does height rt work?
It was concluded that, because of their relatively small sample size, and the limited range of the test scores, height cannot be regarded as useful as a screening tool to detect risk associated with prostate cancer.