Mindfulness-based intervention (with a focus on self-compassion; MBSC) for Postpartum Depression

1
Effectiveness
1
Safety
Oregon Health & Science University, Portland, OR
+3 More
Mindfulness-based intervention (with a focus on self-compassion; MBSC) - Behavioral
Eligibility
18 - 65
Female
Eligible conditions
Postpartum Depression

Study Summary

Maternal Stress on Human Milk and Infant Outcomes

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Eligible Conditions

  • Depression, Postpartum
  • Obstetric Labor, Premature
  • Postpartum Depression
  • Premature Labour

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Mindfulness-based intervention (with a focus on self-compassion; MBSC) will improve 4 primary outcomes and 3 secondary outcomes in patients with Postpartum Depression. Measurement will happen over the course of Baseline to 4 and 8 weeks.

Week 8
Human Milk Proteins & Peptides Change
Infant Metabolomic & Transcriptomic Changes
Maternal Metabolomic & Transcriptomic Changes
Maternal Self-compassion - Biomarker Change
Maternal Self-compassion - Psychometric Measure Change
Maternal Stress - Biomarker Change
Maternal Stress - Psychometric Measure Change

Trial Safety

Safety Estimate

1 of 3

Trial Design

2 Treatment Groups

Control
Mindfulness-based intervention (with a focus on self-compassion; MBSC)

This trial requires 500 total participants across 2 different treatment groups

This trial involves 2 different treatments. Mindfulness-based Intervention (with A Focus On Self-compassion; MBSC) is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Mindfulness-based intervention (with a focus on self-compassion; MBSC)
Behavioral
8-week MBSC intervention with a focus on increasing self-compassion. The MBSC program includes previously developed daily mindfulness practices, guided meditations, routine mindfulness prompts, and four video conference group sessions with a certified mindfulness facilitator.
ControlNo treatment in the control group

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline to 4 and 8 weeks
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly baseline to 4 and 8 weeks for reporting.

Who is running the study

Principal Investigator
Y. C.
Prof. Yimin Chen, Assistant Professor
University of Idaho

Closest Location

Oregon Health & Science University - Portland, OR

Eligibility Criteria

This trial is for female patients between 18 and 65 years old. There is one eligibility criterion to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Mothers of preterm infants (<36 weeks gestation) at Oregon Health and Sciences University

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can postpartum depression be cured?

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The treatment of postpartum depression should be assessed individually, especially in women who had experienced two or more episodes of postpartum depression and experienced depression severity at the time of the third postpartum and the depressive mood state was more stable than before the third postpartum and it was difficult to distinguish between primary postpartum depression and recurrent depressive disorder.

Unverified Answer

What are the signs of postpartum depression?

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PPD symptoms are more likely to persist in postpartum than in non postpartum samples and the overall health of the mother and her baby is worse when PPD is present. Depression symptoms are related to a woman's relationship and employment status.

Unverified Answer

What causes postpartum depression?

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Given the high prevalence of postpartum depression in women, we suggest that screening for postpartum depression during maternity care is valuable. Also, we recommend that health care personnel be trained to identify and treat postpartum depression.

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What is postpartum depression?

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The postpartum period may be a particularly unstable time for the mother and her child. This is an area of increasing concern to health systems because the postpartum period is a particularly stressful time to deliver and because women's health and health care needs are greatest during this time.\n\nProstate enlargement can be caused by benign or malign disease or a benign enlargement of the prostate or the seminal vesicles. The most common cause of benign prostatic enlargement is androgenic hormones (such as androgens, testosterone and DHT) produced by the testes and can reach their highest levels between early puberty and middle age. After the age of 40, androgenic levels diminish.

Unverified Answer

What are common treatments for postpartum depression?

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There were many medications and types of treatments for postpartum depression, but, because of the lack of evidence and information linking treatment algorithms used to treatment outcomes, it is difficult to determine which medicines and treatments were responsible for treatment effects for postpartum depression.

Unverified Answer

How many people get postpartum depression a year in the United States?

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About 1% of women have at least one episode of postpartum depression, while 3.4% of women have recurrent episodes. In this report, women with recurrent episodes are defined as having one or more episodes in each of three or more years, whereas women with a single episode anytime postpartum are defined as having an episode in the first postpartum year. About 18% of women at risk or who develop postpartum depression require treatment.

Unverified Answer

Is mindfulness-based intervention (with a focus on self-compassion; mbsc) typically used in combination with any other treatments?

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MBIT is typically being used in combination with other treatments, including psychotherapies and medications, and in the treatment of women with postpartum distress. Although limited by small numbers, the data in this article suggest that treatment for postpartum women using MBIT is not typically used in isolation or in combination with traditional treatment of postpartum psychotherapy.

Unverified Answer

How serious can postpartum depression be?

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Serious (sometimes severe in terms of social and personal functioning, or even medical consequences) consequences of PPD exist, and more research needs to be done for us to have a better understanding of postpartum depression.

Unverified Answer

Has mindfulness-based intervention (with a focus on self-compassion; mbsc) proven to be more effective than a placebo?

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Results from a recent paper suggests mindful meditation-based interventions with the focus on self-compassion may be more effective in reducing depressive symptoms in women who have given birth by improving positive affective states including self-esteem, mindfulness, social support, and empowerment, and decreasing negative affective states including guilt and anger. The study also shows mindfulness-based interventions may be more effective than a control intervention in preventing long term depressive symptoms in women who have given birth.

Unverified Answer

What is the latest research for postpartum depression?

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In recent years, there has been a dramatic increase in the number of published studies on the prenatal phase (both prenatal diagnosis and prevention), parturition(giving birth), and puerperium (postpartum period). Nevertheless, there is no single, best postpartum treatment option in postpartum depression, and the different treatment options require a comprehensive consideration for treatment of postpartum depression, which includes psychiatric therapy, medications, psychotherapy, or a combination of these treatments.

Unverified Answer

What is mindfulness-based intervention (with a focus on self-compassion; mbsc)?

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The mbsc program increased women's awareness and awareness of the effects of stress and mindfulness practice on their mental condition. The practice of this is beneficial for the prevention and treatment of postpartum depression.

Unverified Answer

What are the latest developments in mindfulness-based intervention (with a focus on self-compassion; mbsc) for therapeutic use?

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In summary, mindfulness-based interventions are widely accepted as effective in the control of a number of chronic medical conditions. Moreover, MBTs have the potential to be used for both psychological and physical conditions. This paper reports on the emerging evidence base of MBI for PPD in children and adults in both a clinical and research setting and identifies potential future directions.

Unverified Answer
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