Alvesco

Asthma, Bronchoconstriction, Chronic Obstructive Pulmonary Disease + 2 more
Treatment
20 Active Studies for Alvesco

What is Alvesco

CiclesonideThe Generic name of this drug
Treatment SummaryCiclesonide (brand name Alvesco) is a steroid medication used to treat breathing problems caused by obstructive airway diseases.
Omnarisis the brand name
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Alvesco Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Omnaris
Ciclesonide
2008
15

Effectiveness

How Alvesco Affects PatientsCiclesonide works by being changed in the body into an active form (des-ciclesonide). This active form attaches to a certain receptor in the body, which helps reduce inflammation associated with allergies. The exact way that ciclesonide works is unknown, but it is known to act on multiple cells and substances that cause inflammation due to allergies.
How Alvesco works in the bodyCiclesonide reduces inflammation by limiting the widening of blood vessels and the amount of white blood cells that can enter the area. It also stops certain molecules from being released, which prevents the formation of other molecules that can cause inflammation. Ciclesonide interacts with the glucocorticoid receptor, which helps to control the expression of genes in the body. This includes the gene that controls interleukin 2, which is a molecule involved in inflammation.

When to interrupt dosage

Condition
Dosage
Administration
Chronic Obstructive Pulmonary Disease
0.05 mg, , 0.08 mg, 0.16 mg, 0.037 mg, 0.05 mg/pump actuation, 0.1 mg/pump actuation, 0.2 mg/pump actuation
, Spray - Nasal, Nasal, Spray, Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered - Nasal, Spray, metered, Spray, metered - Nasal
Asthma
0.05 mg, , 0.08 mg, 0.16 mg, 0.037 mg, 0.05 mg/pump actuation, 0.1 mg/pump actuation, 0.2 mg/pump actuation
, Spray - Nasal, Nasal, Spray, Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered - Nasal, Spray, metered, Spray, metered - Nasal
Bronchoconstriction
0.05 mg, , 0.08 mg, 0.16 mg, 0.037 mg, 0.05 mg/pump actuation, 0.1 mg/pump actuation, 0.2 mg/pump actuation
, Spray - Nasal, Nasal, Spray, Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered - Nasal, Spray, metered, Spray, metered - Nasal
Hay Fever
0.05 mg, , 0.08 mg, 0.16 mg, 0.037 mg, 0.05 mg/pump actuation, 0.1 mg/pump actuation, 0.2 mg/pump actuation
, Spray - Nasal, Nasal, Spray, Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered - Nasal, Spray, metered, Spray, metered - Nasal
Perennial Allergic Rhinitis (PAR)
0.05 mg, , 0.08 mg, 0.16 mg, 0.037 mg, 0.05 mg/pump actuation, 0.1 mg/pump actuation, 0.2 mg/pump actuation
, Spray - Nasal, Nasal, Spray, Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered - Nasal, Spray, metered, Spray, metered - Nasal

Warnings

Alvesco has one contraindication and should be avoided if the following conditions are present in the table.Alvesco Contraindications
Condition
Risk Level
Notes
Status Asthmaticus
Do Not Combine
There are 20 known major drug interactions with Alvesco.
Common Alvesco Drug Interactions
Drug Name
Risk Level
Description
2-Methoxyethanol
Major
The risk or severity of adverse effects can be increased when Ciclesonide is combined with 2-Methoxyethanol.
9-(N-methyl-L-isoleucine)-cyclosporin A
Major
The risk or severity of adverse effects can be increased when Ciclesonide is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Abetimus
Major
The risk or severity of adverse effects can be increased when Ciclesonide is combined with Abetimus.
Acteoside
Major
The risk or severity of adverse effects can be increased when Ciclesonide is combined with Acteoside.
Aldesleukin
Major
The therapeutic efficacy of Aldesleukin can be decreased when used in combination with Ciclesonide.
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Alvesco Novel Uses: Which Conditions Have a Clinical Trial Featuring Alvesco?

There are 245 active trials currently assessing the potential of Alvesco to alleviate Chronic Obstructive Pulmonary Disease (COPD), Asthma and Perennial Allergic Rhinitis (PAR).
Condition
Clinical Trials
Trial Phases
Asthma
155 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4, Early Phase 1, Phase 3
Bronchoconstriction
0 Actively Recruiting
Hay Fever
1 Actively Recruiting
Phase 3
Perennial Allergic Rhinitis (PAR)
0 Actively Recruiting
Chronic Obstructive Pulmonary Disease
102 Actively Recruiting
Phase 3, Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 4

Alvesco Reviews: What are patients saying about Alvesco?

5Patient Review
2/16/2014
Alvesco for Asthma
I've been very pleased with alvesco; I was using asmanex previously and had to use an inhaler daily. Since switching, I only need it every now and then--there's been a significant decrease in my airway reactivity.
5Patient Review
4/8/2014
Alvesco for Severe Chronic Obstructed Lung Disease
This is the only relief I have found.
5Patient Review
5/8/2018
Alvesco for Asthma
Alvesco helped me out a lot by raising my peak flow. I highly recommend it to others who might be struggling with similar issues.
4.7Patient Review
4/10/2013
Alvesco for Asthma Prevention
I'm pleased with the results but I worry about the potential side effects for a young child. My ten year old experienced knee joint pain, headaches, and stomach aches after taking this medication. They also woke up at 3am every morning and had difficulty falling back asleep.
4.3Patient Review
6/1/2018
Alvesco for Asthma
I experienced some chest pain and cramping after starting this medication, but it subsided after a couple of weeks. However, whenever I stop and start the medication again, the symptoms reappear.
4Patient Review
10/14/2015
Alvesco for Asthma
It seems like when I only have 10 puffs of this left, it's more propellant than medicine. As a result, my symptoms aren't well controlled and I end up having to buy a new inhaler sooner than anticipated.
4Patient Review
4/5/2016
Alvesco for Asthma
My previous inhaler was discontinued, so I had to switch. I tried a bunch of the newer ones but they all made me sick. So then my allergist put me on a trial of Alvesco and it's been WAY better. Granted, I still have some COPD symptoms, but overall this has helped a lot in conjunction with my rescue inhaler. The only downside is how expensive it is--especially now that I have Medicare coverage.
3.7Patient Review
9/17/2020
Alvesco for Asthma
I had to find a new medication because my old one was discontinued. Alvesco worked well, but I unfortunately developed an itchy rash and hives, so I had to discontinue it.
3.3Patient Review
3/21/2022
Alvesco for Controller Medication for Asthma
The dose meter on this product starts at 60 and goes down to 20 when it's empty. I've gone through dozens of these, and they all seem to run out right at 20 doses. The pharmacy only gives me six inhalers for a three-month period, but considering I need two puffs twice a day, that always runs out long before the next refill is due.
3Patient Review
9/18/2013
Alvesco for Asthma
Alvesco has given me some nasty indigestion and white spots on the back of my throat. I'll be switching to a different inhaler per my doctor's recommendation.
2.7Patient Review
2/27/2014
Alvesco for Asthma
ADVAIR was honestly really scary for me. I had so many side effects that it nearly killed me. I'm glad I switched to Alvesco, which has helped a lot but still gives me some jitters.
2.3Patient Review
9/20/2014
Alvesco for Asthma Prevention
I tried this medication for the first time and immediately after taking two puffs I developed a moderate asthma attack, headache, dizziness, disorientation, heart palpitations, a blood nose and after half an hour of puffing on Ventolin my heart was racing and I felt very shaky. I became extremely weak then lay down and slept for three hours. Obviously an allergic reaction.
2Patient Review
8/10/2019
Alvesco for Controller Medication for Asthma
Qvar was much more effective for me, to the point where I could go a few days without using it. Alvesco is unfortunately not working as well, and my asthma has gotten worse since starting it.
2Patient Review
7/2/2022
Alvesco for Asthma Prevention
I had serious difficulty breathing after taking this treatment, to the point where I was having asthma attacks every 12 hours. My nose was blocked, my eyes were red and itchy, and I felt like I was going to vomit. Thankfully, I stopped taking the medication and have started to feel better--though I'm still not 100% recovered.
1.7Patient Review
2/12/2022
Alvesco for Asthma
This didn't work for me.
1Patient Review
7/31/2022
Alvesco for Asthma
One puff of this and I was hit with a nasty headache, loss of appetite, fatigue, and nausea. My lungs felt like they were coated in chemicals, and the taste lingered all day. I was told to take one in the morning and one at night, but I couldn't bring myself to do it again after the first time. Yes, my asthma went away for almost a full day—but the side effects just aren't worth it.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about alvesco

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Alvesco used for?

"Alvesco is indicated for the long-term maintenance treatment of asthma, as a preventative measure, in patients aged 12 and over. It is NOT indicated for the relief of short-term bronchospasm or for use in children under 12."

Answered by AI

Are there steroids in Alvesco?

"Alvesco is a man-made corticosteroid that prevents the release of substances in the body that cause inflammation. It is used to prevent asthma attacks in adults and children who are at least 12 years old."

Answered by AI

Is Alvesco and albuterol the same?

"Most people taking Alvesco (ciclesonide) will also be prescribed a rescue medication such as albuterol or levalbuterol. Alvesco (ciclesonide) is a maintenance inhaler that should be taken 2 times every day to prevent asthma symptoms, while rescue medications are used during an asthma attack to help control symptoms."

Answered by AI

What kind of steroid is Alvesco?

"Alvesco's active drug ingredient is ciclesonide, an inhaled corticosteroid. Advair HFA's two active ingredients are fluticasone and salmeterol. Fluticasone is an inhaled corticosteroid, and salmeterol is a long-acting beta-agonist."

Answered by AI

Clinical Trials for Alvesco

Have you considered Alvesco clinical trials? We made a collection of clinical trials featuring Alvesco, we think they might fit your search criteria.
Have you considered Alvesco clinical trials? We made a collection of clinical trials featuring Alvesco, we think they might fit your search criteria.
Have you considered Alvesco clinical trials? We made a collection of clinical trials featuring Alvesco, we think they might fit your search criteria.