Slynd

Birth Control, Acne Vulgaris, Folate supplementation therapy + 9 more
Treatment
20 Active Studies for Slynd

What is Slynd

DrospirenoneThe Generic name of this drug
Treatment SummaryDrospirenone is a synthetic hormone used in combination with another hormone, called estetrol, as an oral contraceptive. It is also used with estrogen to control acne and premenstrual dysphoric disorder (PMDD). There have been safety concerns that the use of drospirenone may increase the risk of venous thromboembolism, however, studies have been conflicting. The FDA concluded that the risk of thromboembolism is still lower than the risk during pregnancy or after giving birth.
Yasminis the brand name
image of different drug pills on a surface
Slynd Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Yasmin
Drospirenone
2001
64

Effectiveness

How Slynd Affects PatientsDrospirenone is an oral contraceptive that prevents pregnancy by stopping the maturation of follicles and ovulation. It also has anti-androgen effects, which can help improve acne and hirsutism. When taken with ethinyl estradiol, it has been shown to positively affect cholesterol levels. Due to its similarity to natural progesterone, drospirenone is thought to cause fewer side effects than other progesterone contraceptives, such as breast tenderness and mood swings. However, it may increase the risk of venous thromboembolism and cardiovascular events, and smokers or women aged 35 or older are
How Slynd works in the bodyDrospirenone and ethinyl estradiol work together to prevent pregnancy. They do this by blocking the hormones that trigger ovulation, making it harder for sperm to reach the egg. Drospirenone also has anti-androgenic effects, which means it stops dihydrotestosterone from binding to its receptor and reduces the amount of androgens produced in the ovaries. This helps to treat acne and hirsutism, as well as reducing edema in the sebaceous follicles.

When to interrupt dosage

The quantity of Slynd is contingent upon the diagnosed affliction, such as moderate to severe indications, Menopause and Post-Menarche. The measure also varies as per the technique of delivery (e.g. Tablet, film coated - Oral or Oral) enumerated in the table beneath.
Condition
Dosage
Administration
Birth Control
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet, Kit - Oral
moderate to severe symptoms
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet, Kit - Oral
N-Cadherins
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet, Kit - Oral
Hormonal Contraception
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet, Kit - Oral
Vasomotor System
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet, Kit - Oral
Acne Vulgaris
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet, Kit - Oral
Adherence to Oral Contraceptive Therapy
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet, Kit - Oral
Atrophic
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet, Kit - Oral
Post-Menarche
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet, Kit - Oral
Atrophy of vulva
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet, Kit - Oral
Folate supplementation therapy
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet, Kit - Oral
Hot flashes
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet, Kit - Oral

Warnings

Slynd has twenty-six contraindications and should not be utilized when encountering any of the situations described in the subsequent table.Slynd Contraindications
Condition
Risk Level
Notes
Chronic Kidney Disease
Do Not Combine
Venous Thrombosis
Do Not Combine
Neoplasms, Hormone-Dependent
Do Not Combine
Migraine with Aura
Do Not Combine
Porphyrias
Do Not Combine
Breast
Do Not Combine
suspected pregnancy
Do Not Combine
Breast Milk Production
Do Not Combine
Metrorrhagia
Do Not Combine
Hypersensitivity
Do Not Combine
Liver Failure, Acute
Do Not Combine
Acute Kidney Injury
Do Not Combine
Deep Vein Thrombosis (DVT)
Do Not Combine
Vision Loss
Do Not Combine
Endometrial Hyperplasia
Do Not Combine
Tobacco Use
Do Not Combine
Liver Function Tests
Do Not Combine
Thrombophilia
Do Not Combine
Thromboembolism
Do Not Combine
high risk of arterial thrombotic disease
Do Not Combine
estrogen-dependent neoplasia
Do Not Combine
Liver Neoplasms
Do Not Combine
Adrenal Insufficiency
Do Not Combine
Thrombosis
Do Not Combine
Breast
Do Not Combine
estrogen-dependent neoplasia
Do Not Combine
There are 20 known major drug interactions with Slynd.
Common Slynd Drug Interactions
Drug Name
Risk Level
Description
Tranexamic acid
Major
Drospirenone may increase the thrombogenic activities of Tranexamic acid.
Acetohexamide
Minor
The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Drospirenone.
Agmatine
Minor
The risk or severity of hyperkalemia can be increased when Drospirenone is combined with Agmatine.
Aliskiren
Minor
The risk or severity of hyperkalemia can be increased when Drospirenone is combined with Aliskiren.
Anisodamine
Minor
The risk or severity of hyperkalemia can be increased when Drospirenone is combined with Anisodamine.
Slynd Toxicity & Overdose RiskDrospirenone has a low level of toxicity in rats, with an oral LD50 greater than 2000mg/kg. Overdosing on drospirenone may lead to nausea or an irregular menstrual cycle. Additionally, drospirenone can affect the levels of serum sodium and potassium, which should be monitored in cases of overdose, along with metabolic acidosis and hyperkalemia.
image of a doctor in a lab doing drug, clinical research

Slynd Novel Uses: Which Conditions Have a Clinical Trial Featuring Slynd?

104 active investigations are currently assessing the potential of Slynd in addressing Acne Vulgaris, Post-Menarche and N-Cadherin related issues.
Condition
Clinical Trials
Trial Phases
N-Cadherins
0 Actively Recruiting
moderate to severe symptoms
0 Actively Recruiting
Folate supplementation therapy
0 Actively Recruiting
Acne Vulgaris
0 Actively Recruiting
Atrophy of vulva
1 Actively Recruiting
Not Applicable
Hormonal Contraception
0 Actively Recruiting
Hot flashes
19 Actively Recruiting
Not Applicable, Phase 4, Phase 2, Early Phase 1, Phase 3
Post-Menarche
0 Actively Recruiting
Adherence to Oral Contraceptive Therapy
0 Actively Recruiting
Birth Control
22 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Early Phase 1, Phase 2
Atrophic
4 Actively Recruiting
Phase 4, Not Applicable
Vasomotor System
0 Actively Recruiting

Slynd Reviews: What are patients saying about Slynd?

5Patient Review
7/25/2022
Slynd for Birth Control
My doctor recommended Slynd when I started having breakthrough bleeding and I'm so glad she did! It's helped to stabilize my mood and stop the bleeding completely. Plus, I haven't experienced any negative side effects like weight gain or headaches.
4.3Patient Review
8/1/2022
Slynd for Birth Control
I switched to the pill after having negative experiences with the Paraguard IUD. I've been using Slynd for about a year now, and it's helped me in so many ways. My cramps have lessened, my anxiety has decreased, and I love that there is a 24-hour grace period if you forget to take your pill. The only downside is that I have noticed a slight increase in weight; however, this is not drastic by any means. All things considered, I am very pleased with this birth control!
3Patient Review
7/28/2022
Slynd for Birth Control
I was prescribed Slynd for post-party contraception while breastfeeding. I gained so much weight on it that I stopped taking it. I had been on birth control for 15 years before this and never experienced the weight gain like I did with this pill. It was HORRIBLE!
2.3Patient Review
10/22/2022
Slynd for Birth Control
I'm starting to get chest acne from this pill--something I've never experienced in my 35 years.
2Patient Review
10/15/2022
Slynd for Birth Control
What they don't tell you is that Slynd can make IBS worse and increase the risk of colon cancer if it's something that runs in your family. I lost a ton of weight while taking this medication, and felt sick and miserable the whole time.
2Patient Review
6/12/2022
Slynd for Birth Control
I've been on this medication for two months and I absolutely hate it. I'm constantly in a bad mood, flipping out randomly. I want my old birth control back. This one hasn't given me any period, which is extremely odd.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about slynd

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does Slynd make you gain weight?

"The following side effects may occur: feeling sick to your stomach (nausea), throwing up (vomiting), headache, bloating, soreness in your breasts, acne, or weight gain."

Answered by AI

What type of birth control is Slynd?

"The Slynd ® pill is a birth control pill that can be used by females who can become pregnant to prevent pregnancy."

Answered by AI

Why is Slynd different?

"In other words — our pill works with you, not against you.

At Slynd®, we believe that birth control should be designed to fit more lifestyles, body types, and health situations. Our estrogen-free formula has a 24-hour missed pill window and doesn't contain any unnecessary hormones. Our pill works with you, not against you."

Answered by AI

Is Slynd birth control good?

"Slynd has a mixed reputation when it comes to Birth control, with an average rating of 5.2 out of 10 from 248 reviewers. While 39% reported positive experiences, 43% had negative ones."

Answered by AI

Clinical Trials for Slynd

Image of Erevna Innovations Inc. in Montreal, Canada.

Sculptra + Restylane for Post-Menopausal Skin Concerns

40 - 65
Female
Montreal, Canada
The post-menopausal state is marked by a sharp decline in estrogen, leading to significant structural and functional changes in the skin, including collagen loss, dryness, thinning, and reduced elasticity. To address these concerns, aesthetic injectables products such as Sculptra® Aesthetic (poly-L-lactic-acid \[PLLA- SCA\]) and Restylane Skinboosters®\[HASBV\] (small-particle hyaluronic acid - SP-HA) can be used. PLLA-SCA stimulates collagen production via cellular activation (biostimulator), gradually improving dermal structure. HASBV enhances hydration, elasticity, and skin texture when injected under the skin. Considering that hydration and laxity represent the primary aesthetic concerns in this patient population. Targeted treatment with SP-HA (HASBV) to improve hydration and PLLA-SCA to address laxity have been shown to produce significant clinical outcomes by directly addressing these key dermal deficiencies. This approach forms the basis of the current study.
Phase 4
Recruiting
Erevna Innovations Inc.Andreas Nikolis, MD, PhD
Have you considered Slynd clinical trials? We made a collection of clinical trials featuring Slynd, we think they might fit your search criteria.Go to Trials
Image of University of California, San Diego in La Jolla, United States.

Lidocaine for Pain Control in Birth Control

18 - 50
Female
La Jolla, CA
The goal of this research study is to learn more about how different uses of a numbing medication might affect pain levels while getting an IUD placed. The investigators are also studying participants opinions of their clinicians' empathy. The investigators are inviting patients who arrive at their clinic visit seeking an IUD. Usually, at University of California, San Diego (UCSD), for patients who have never delivered a baby, clinicians use a buffered paracervical block for before IUD placement. The purpose of this research study is to investigate whether a "buffered" (2 cc of sodium bicarbonate, 18 cc of 1% lidocaine) paracervical block (numbing medication given on both sides of the cervix) is effective in reducing pain during IUD placement in individuals with prior C-sections, the difference between buffered and unbuffered for nulliparous patients, and whether a medicated gel reduces pain with the paracervical block.
Recruiting
Paid Trial
University of California, San DiegoSheila K Mody, MD, MPH
Have you considered Slynd clinical trials? We made a collection of clinical trials featuring Slynd, we think they might fit your search criteria.Go to Trials
Image of Calabasas Pharmacy in Calabasas, United States.

Electronic Health Record Platform for Birth Control

18 - 51
Female
Calabasas, CA
Hormonal contraceptives are medications that require a prescription, traditionally from a physician or advanced practice provider. Over the past decade, pharmacists have gained the authority to prescribe contraceptives in many states, allowing patients to access these medications directly in pharmacies without first seeing another healthcare provider. The Pharmacist Resource to Implement Services as Modules (PRISM) is an Electronic Health Record platform designed to streamline workflows and provide clinical decision support, making it easier and safer to deliver clinical services in community pharmacies. This pilot study will evaluate patient-reported outcomes for women receiving contraceptive services from pharmacists using the PRISM platform at five community pharmacies across the United States over a 12-week period. The study will assess the quality of care, contraception continuation and failure rates, side effect rates, preventative healthcare utilization, and overall patient experience with pharmacy contraceptive services.
Waitlist Available
Has No Placebo
Calabasas Pharmacy (+4 Sites)OvaryIt, LLC
Image of Noll Laboratory in University Park, United States.

Estradiol and Elagolix for Menopause

42 - 64
Female
University Park, PA
The frequency and severity of heat waves has increased in the last decades. Older adults (over 65 years) have impaired responses to heat stress making them at increased risk for adverse events. Previous heat waves report that women over 65 experience worse health outcomes than any other age group and age matched men. Aging and reproductive hormones, specifically estrogen, independently alter responses to heat stress. However, the combined effects of low estrogen following menopause and aging on the response to heat stress are unknown. In this study, the investigators will identify the role of estrogen in pre and post menopausal women on thermoregulatory responses to heat stress.
Phase 4
Recruiting
Noll LaboratoryW. Larry Kenney, Ph.D.
Have you considered Slynd clinical trials? We made a collection of clinical trials featuring Slynd, we think they might fit your search criteria.Go to Trials
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