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What is Desogen
DesogestrelThe Generic name of this drug
Treatment SummaryDesogestrel is a drug used in combination with Ethinyl Estradiol to treat certain medical conditions. It is a synthetic version of a naturally occurring plant steroid, and was first developed and approved in the U.S. in 1992 by Organon USA Inc. Desogestrel is a third generation progestogen, meaning it works by blocking the body's natural hormones to help with certain conditions.
Desogenis the brand name
Desogen Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Desogen
Desogestrel
1992
68
Effectiveness
How Desogen Affects PatientsDesogestrel is used to modify the hormones in the reproductive system, delaying the onset of menstruation and thickening the vaginal fluid. It can also increase insulin secretion and resistance, and increase fat storage in the body. The main therapeutic effect of desogestrel is that it prevents ovulation 97% of the time. However, it can also increase the risk of blood clots and thromboembolism. On the other hand, desogestrel does not make much of a difference to total cholesterol levels, as it only causes a change of 10% or less.
How Desogen works in the bodyDesogestrel enters cells and binds to a type of receptor that responds to progesterone. This binding is like a switch that changes the cell's instructions, which can lead to different kinds of effects. The active form of desogestrel, etonogestrel, is especially good at producing a progesterone-like effect while having low levels of androgen.
When to interrupt dosage
The proposed dose of Desogen is contingent upon the diagnosed condition, including Birth Control, Nursing Women and Hormonal Contraception. The dosage fluctuates, based on the delivery strategy (e.g. Kit or Kit; Tablet - Oral) detailed in the table below.Condition
Dosage
Administration
Hormonal Contraception
, 0.15 mg, 0.1 mg, 0.125 mg, 0.375 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Birth Control
, 0.15 mg, 0.1 mg, 0.125 mg, 0.375 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Warnings
Desogen has twenty-five contraindications and should not be employed when having any of the conditions outlined in the subsequent table.Desogen ContraindicationsCondition
Risk Level
Notes
Cerebrovascular Diseases
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Liver Cancer
Do Not Combine
Endometrial Carcinoma
Do Not Combine
Thromboembolism
Do Not Combine
Thromboembolism
Do Not Combine
Major Surgery
Do Not Combine
benign hepatic adenoma
Do Not Combine
Breast Cancer
Do Not Combine
hepatocellular disease
Do Not Combine
undiagnosed abnormal genital bleeding
Do Not Combine
Breast
Do Not Combine
Type 2 Diabetes
Do Not Combine
Coronary Artery Disease (CAD)
Do Not Combine
Thrombophlebitis
Do Not Combine
Thrombophilia
Do Not Combine
Diastolic blood pressure
Do Not Combine
> 160 mm Hg systolic blood pressure
Do Not Combine
Jaundice, Obstructive
Do Not Combine
history of deep vein thrombophlebitis
Do Not Combine
Icterus
Do Not Combine
focal neurological symptoms
Do Not Combine
valvular heart disease with complications
Do Not Combine
estrogen-dependent neoplasia
Do Not Combine
Common Desogen Drug Interactions
Drug Name
Risk Level
Description
Axitinib
Major
The metabolism of Axitinib can be increased when combined with Desogestrel.
Belinostat
Major
The metabolism of Belinostat can be increased when combined with Desogestrel.
Binimetinib
Major
The metabolism of Binimetinib can be increased when combined with Desogestrel.
Enasidenib
Major
The metabolism of Enasidenib can be increased when combined with Desogestrel.
Etoposide
Major
The metabolism of Etoposide can be increased when combined with Desogestrel.
Desogen Toxicity & Overdose RiskTaking a lot of desogestrel has been found to cause strong hormonal effects, but not long-term damage. The highest toxic dose for rats is higher than 2000mg/kg. Taking too much of this drug may cause nausea or stop menstruation, but it does not seem to raise the risk of breast cancer. Some studies have suggested that desogestrel may lead to cell changes in the cervix, but the results are not certain.
Desogen Novel Uses: Which Conditions Have a Clinical Trial Featuring Desogen?
38 active trials are currently underway to evaluate the potential of Desogen for Nursing Women, Birth Control and Hormonal Contraception.Condition
Clinical Trials
Trial Phases
Birth Control
31 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Early Phase 1
Hormonal Contraception
0 Actively Recruiting
Desogen Reviews: What are patients saying about Desogen?
5Patient Review
4/26/2016 I've tried a few different kinds of birth control in the past, but I've been on this one for three months. I had a really bad reaction to the NUVARING, so this has been a great alternative. The hardest thing is remembering to take it every day, but other than that I haven't had any issues.
4Patient Review
1/12/2012 The first week was difficult as I felt nauseous all the time. For the next three weeks, my mood swings were really bad and I had no patience for anyone, especially my two-year-old child. By the second week, I also started having digestive problems like diarrhea and irregular bowel movements. Thankfully, I'm on the one-week break now and feeling much better.
4Patient Review
4/20/2011 I've been taking Desogen on and off for 15 years now. I started up again in June 2010 but then developed non-stop bleeding that lasted for six weeks. This is the only time I have ever had problems with the drug. I'm no longer taking it per my doctor's instructions.
4Patient Review
1/11/2011 Bloating and farting after eating were both immediately relieved after starting this medication. I only take it at night to avoid nausea, but that's been manageable. After just one month, I've already seen a significant difference.
4Patient Review
3/19/2014 Though this was effective in preventing pregnancy, I experienced some significant side effects that made it difficult to justify taking the medication. In addition to gaining weight, I felt tired all the time. The one upside was that my hormonal acne around my chin cleared up.
4Patient Review
5/10/2012 I've been feeling very moody lately. One minute I'm happy and the next I'm angry. My bleeding is still heavy and I'm dealing with a lot of bloating.
3.3Patient Review
9/16/2013 When I first started taking this drug, I was on it for two months straight. It was fine except that I felt suicidal the whole time. So, I took a month break and now I've been back on it for about a month and it's awful. In the last two weeks, I've gained 10 pounds (even though I only eat once a day and have a very active job). Plus, I'm nauseous in the morning, sad or angry most of the day, and sluggish.
3Patient Review
11/14/2012 I haven't been feeling like myself since starting this medication. My emotions are all over the place and I've been short-tempered and snippy. It's put a damper on my sex life and I just don't have the same energy levels.
3Patient Review
11/10/2013 I first started noticing the headaches. Then, my period lasted for three weeks without any respite. In addition, my breasts have been sensitive and I get tired really easily. There are also times when I'll suddenly become very horny or very turned off for no apparent reason.
3Patient Review
3/17/2012 Though there was no risk of pregnancy with this treatment, it killed my sex drive, caused breakouts, and left me feeling fairly depressed.
1Patient Review
11/25/2014 I had a stroke because of this medicine. Please be very careful and research all potential side effects before taking any medication.
Patient Q&A Section about desogen
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the generic name for Desogen?
"- Desogen (desogestrel / ethinyl estradiol) is a birth control pill. It is a combination of two hormones, desogestrel and ethinyl estradiol, that prevents ovulation (the release of an egg from the ovary).
Desogen (desogestrel / ethinyl estradiol) is a birth control pill that contains a combination of two hormones, desogestrel and ethinyl estradiol. These hormones work together to prevent ovulation, which is the release of an egg from the ovary."
Answered by AI
What is Desogen used for?
"This medication, which contains a combination of two hormones (a progestin and an estrogen), is used to prevent pregnancy. In addition to preventing pregnancy, birth control pills may also make your periods more regular, decrease blood loss and painful periods, decrease your risk of ovarian cysts, and treat acne."
Answered by AI
What kind of birth control is Desogen?
"Desogen is a prescription medicine that can be used as contraception to prevent pregnancy. It may be used alone or with other medications."
Answered by AI
Does Desogen cause weight gain?
"Some women report gaining weight when they start taking Desogen, along with other birth control pills, but there is no evidence that the pill causes dramatic changes in weight."
Answered by AI