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Progestin Contraceptives for Birth Control Effects
Study Summary
This trial will look at how progestin contraception affects menstrual patterns and the endometrium. Participants will receive contraceptive implant or injectable for 12 months & be asked to report bleeding patterns. 4 endometrial biopsies & blood draws, physical exams & pregnancy tests will be done. sCRNAseq will be used to profile the endometrium.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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- I have experienced unusual bleeding from my uterus.I have a bleeding disorder.I am between 18 and 40 years old and in good health.I regularly take NSAIDs daily for at least two weeks a month.I can safely use birth control shots or implants.I have been diagnosed with polycystic ovary syndrome.I am not taking any drugs that affect the P450 enzyme system.I am using hormonal or intrauterine contraceptives, or other hormone treatments.I have a known condition affecting my uterus.I am currently using blood thinners.I use CBD, THC, or marijuana regularly (more than 3 times a week).
- Group 1: DMPA
- Group 2: Etonogestrel implant
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Does the selection criteria for this trial allow people aged 25 and over to participate?
"This study is actively searching for participants aged between 18 and 40 years old."
What are the qualifications to take part in this clinical exploration?
"This clinical trial is currently enrolling 52 individuals, who must be between 18 and 40 years old. Additionally, all participants should have reliable birth control methods in place."
Are there any open slots in this research endeavor for participants?
"The information available on clinicaltrials.gov reveals that this trial has concluded recruitment. It was initially made public in March 1st, 2023 and the most recent update came February 25th, 2023. Notwithstanding, there are still 53 other trials looking for participants at present time."
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