DMPA for Birth Control

OHSU, Portland, OR
Birth ControlEtonogestrel implant - Drug
18 - 40
What conditions do you have?

Study Summary

This trial will look at how progestin contraception affects menstrual patterns and the endometrium. Participants will receive contraceptive implant or injectable for 12 months & be asked to report bleeding patterns. 4 endometrial biopsies & blood draws, physical exams & pregnancy tests will be done. sCRNAseq will be used to profile the endometrium.

Treatment Effectiveness

Phase-Based Effectiveness

1 of 3
Phase < 1

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: Baseline to 6 months

Baseline to 6 months
The proportion of participants who experienced endometrial changes

Trial Safety

Phase-Based Safety

1 of 3

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

2 Treatment Groups

1 of 2
Etonogestrel implant
1 of 2

Active Control

52 Total Participants · 2 Treatment Groups

Primary Treatment: DMPA · No Placebo Group · Phase < 1

ActiveComparator Group · 1 Intervention: DMPA · Intervention Types: Drug
Etonogestrel implant
ActiveComparator Group · 1 Intervention: Etonogestrel implant · Intervention Types: Drug

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: baseline to 6 months

Who is running the clinical trial?

Oregon Health and Science UniversityLead Sponsor
914 Previous Clinical Trials
6,830,447 Total Patients Enrolled
Alison Edelman, MDPrincipal InvestigatorOregon Health and Science University
2 Previous Clinical Trials
88 Total Patients Enrolled

Eligibility Criteria

Age 18 - 40 · Female Participants · 1 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
Your Body Mass Index is between 19 and 35.

Frequently Asked Questions

Does the selection criteria for this trial allow people aged 25 and over to participate?

"This study is actively searching for participants aged between 18 and 40 years old." - Anonymous Online Contributor

Unverified Answer

What are the qualifications to take part in this clinical exploration?

"This clinical trial is currently enrolling 52 individuals, who must be between 18 and 40 years old. Additionally, all participants should have reliable birth control methods in place." - Anonymous Online Contributor

Unverified Answer

Are there any open slots in this research endeavor for participants?

"The information available on reveals that this trial has concluded recruitment. It was initially made public in March 1st, 2023 and the most recent update came February 25th, 2023. Notwithstanding, there are still 53 other trials looking for participants at present time." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.