Yasmin

Birth Control, Acne Vulgaris, Folate supplementation therapy + 9 more
Treatment
20 Active Studies for Yasmin

What is Yasmin

DrospirenoneThe Generic name of this drug
Treatment SummaryDrospirenone is a synthetic progestin used in combination with ethinyl estradiol or estetrol as an oral contraceptive therapy. It is also used to treat acne and premenstrual dysphoric disorder (PMDD). There is some concern that drospirenone may increase the risk of venous thromboembolism; however, studies are conflicting and the FDA has concluded that the risk remains unclear. Generally, the risk of venous thromboembolism from using drospirenone is lower than the risk during pregnancy and postpartum.
Yasminis the brand name
image of different drug pills on a surface
Yasmin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Yasmin
Drospirenone
2001
64

Effectiveness

How Yasmin Affects PatientsDrospirenone prevents pregnancy by blocking ovulation. It may also help with acne and excess hair growth. When taken in combination with ethinyl estradiol, it has been shown to lower the levels of certain fats (lipids) in the blood. Since it is similar to natural progesterone, it is thought to cause fewer side effects such as breast tenderness and mood swings. However, drospirenone may increase the risk of developing blood clots, heart attack, or stroke. Smokers should not take this drug and those at risk of high potassium levels should avoid it as well.
How Yasmin works in the bodyDrospirenone and ethinyl estradiol work together to prevent pregnancy in several ways. They stop the release of hormones that trigger ovulation, creating a barrier to fertilization. They also make cervical mucus thicker and harder for sperm to pass through, and make it harder for a fertilized egg to implant itself. Drospirenone also has some anti-androgenic effects, blocking the effects of male hormones and helping to treat acne and hirsutism. It also reduces swelling in sebaceous follicles which can help with acne.

When to interrupt dosage

The suggested dosage of Yasmin is contingent upon the identified problem, including moderate to severe symptoms, Menopause and Post-Menarche. The amount of dosage is dependent on the technique of delivery (e.g. Tablet, film coated - Oral or Oral) as outlined in the table below.
Condition
Dosage
Administration
Birth Control
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
moderate to severe symptoms
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
N-Cadherins
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
Hormonal Contraception
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
Vasomotor System
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
Acne Vulgaris
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
Adherence to Oral Contraceptive Therapy
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
Atrophic
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
Post-Menarche
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
Atrophy of vulva
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
Folate supplementation therapy
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
Hot flashes
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral

Warnings

Yasmin Contraindications
Condition
Risk Level
Notes
Chronic Kidney Disease
Do Not Combine
Venous Thrombosis
Do Not Combine
Neoplasms, Hormone-Dependent
Do Not Combine
Migraine with Aura
Do Not Combine
Porphyrias
Do Not Combine
Breast
Do Not Combine
suspected pregnancy
Do Not Combine
Breast Milk Production
Do Not Combine
Metrorrhagia
Do Not Combine
Hypersensitivity
Do Not Combine
Liver Failure, Acute
Do Not Combine
Acute Kidney Injury
Do Not Combine
Deep Vein Thrombosis (DVT)
Do Not Combine
Vision Loss
Do Not Combine
Endometrial Hyperplasia
Do Not Combine
Tobacco Use
Do Not Combine
Liver Function Tests
Do Not Combine
Thrombophilia
Do Not Combine
Thromboembolism
Do Not Combine
high risk of arterial thrombotic disease
Do Not Combine
estrogen-dependent neoplasia
Do Not Combine
Liver Neoplasms
Do Not Combine
Adrenal Insufficiency
Do Not Combine
Thrombosis
Do Not Combine
Breast
Do Not Combine
estrogen-dependent neoplasia
Do Not Combine
There are 20 known major drug interactions with Yasmin.
Common Yasmin Drug Interactions
Drug Name
Risk Level
Description
Tranexamic acid
Major
Drospirenone may increase the thrombogenic activities of Tranexamic acid.
Acetohexamide
Minor
The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Drospirenone.
Agmatine
Minor
The risk or severity of hyperkalemia can be increased when Drospirenone is combined with Agmatine.
Aliskiren
Minor
The risk or severity of hyperkalemia can be increased when Drospirenone is combined with Aliskiren.
Anisodamine
Minor
The risk or severity of hyperkalemia can be increased when Drospirenone is combined with Anisodamine.
Yasmin Toxicity & Overdose RiskThe lowest toxic dose of drospirenone in rats has been found to be greater than 2000mg/kg. Overdosing on drospirenone may cause nausea, unusual bleeding, and changes in the levels of serum sodium and potassium. If drospirenone is overdosed, medical professionals should also check for signs of acidosis or too much potassium in the blood.
image of a doctor in a lab doing drug, clinical research

Yasmin Novel Uses: Which Conditions Have a Clinical Trial Featuring Yasmin?

104 active clinical trials are examining the possible uses of Yasmin in treating Acne Vulgaris, Post-Menarcheal states and N-Cadherin related conditions.
Condition
Clinical Trials
Trial Phases
N-Cadherins
0 Actively Recruiting
moderate to severe symptoms
0 Actively Recruiting
Folate supplementation therapy
0 Actively Recruiting
Acne Vulgaris
0 Actively Recruiting
Atrophy of vulva
1 Actively Recruiting
Not Applicable
Hormonal Contraception
0 Actively Recruiting
Hot flashes
19 Actively Recruiting
Not Applicable, Phase 4, Phase 2, Early Phase 1, Phase 3
Post-Menarche
0 Actively Recruiting
Adherence to Oral Contraceptive Therapy
0 Actively Recruiting
Birth Control
22 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Early Phase 1, Phase 2
Atrophic
4 Actively Recruiting
Phase 4, Not Applicable
Vasomotor System
0 Actively Recruiting

Yasmin Reviews: What are patients saying about Yasmin?

4.3Patient Review
4/24/2020
Yasmin for Birth Control
I would not recommend this pill to anyone. It killed my best friend by causing severe blood clots and internal bleeding.
4.3Patient Review
5/23/2022
Yasmin for Acne
I've tried a number of different pills, and this is the only one that's managed to clear my skin within six months.
3.7Patient Review
12/9/2021
Yasmin for Birth Control
I was on this pill for seven years and I was very happy with it. The problems only appeared after I stopped taking the pill - PCOS & depression. I almost killed myself because of the overwhelming emotions, and having difficulty to get pregnant. I'm shocked nobody warned me of this side effect before, and so many women actually went through the same depression issue after the pill. If you have to use it, don't use it continuously for long periods of time.
2.7Patient Review
4/9/2022
Yasmin for Birth Control
I started taking this medication a few years ago and didn't have any adverse effects. Recently, I started again and began spotting within a few days.
2.3Patient Review
3/22/2022
Yasmin for Birth Control
This pill did what it was supposed to while I took it. However, soon after going off the pill I started losing a lot of hair, which has still not returned to normal six months later. Just wanted to give a warning to other girls considering this treatment.
2.3Patient Review
3/13/2022
Yasmin for Acne
Unfortunately, this medication made me really hungry all the time. As a result, I gained four kilograms in just three months. I was also constantly craving sugary and fatty foods, which isn't great for my health. On the plus side, it didn't have any negative effect on my skin.
2Patient Review
12/1/2018
Yasmin for Birth Control
This birth control pill has been the best at regulating my period and lightening it. While I did have slight nausea and breakthrough bleeding during the first month, these side effects went away by month two.
2Patient Review
7/18/2022
Yasmin for Birth Control
I had some really intolerable mood swings while taking the first pack of this medication. My period also started during the active pills, which was very inconvenient. I'm currently on my second pack and have been spotting for a few days. I've also been feeling nauseous in the morning. Overall, I would not recommend this pill to anyone.
1.7Patient Review
10/19/2022
Yasmin for Birth Control
I had a stroke at only 17 years old after starting this pill, even though there's no history of strokes in my family. Be aware that this is a possible side effect. I also started having headaches 9 months before the stroke occurred; however, they went away as soon as I stopped taking the pill.
1Patient Review
10/17/2021
Yasmin for Disease of Ovaries with Cysts
Threw me into a deep depression. The pill should not be the first option for women when dealing with PCOS/ acne/ period problems, etc. There are so many other medicines or natural remedies to assist with everything; it’s a shame the health system just throws the pill at women who are struggling and calls it a day.
1Patient Review
6/1/2018
Yasmin for Birth Control
I tried this contraceptive for the first time a few weeks ago and unfortunately had some bad reactions to it. I developed pigmentation on my legs and felt incredibly itchy all over my body.
1Patient Review
9/8/2021
Yasmin for Birth Control
I had some serious heart palpitations after taking this pill for just one week. I'm glad I read the reviews before continuing- I don't want to be a statistic.
1Patient Review
4/9/2017
Yasmin for Birth Control
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about yasmin

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What type of birth control is Yasmin?

"Thickening cervical mucus to keep sperm from getting to the egg

Yasmin is a combination oral contraceptive that contains a progestin and an estrogen. The progestin suppresses ovulation and the estrogen thickens cervical mucus to keep sperm from getting to the egg."

Answered by AI

Does Yasmin have side effects?

"These are some of the possible side effects of taking the birth control pill. Nausea, vomiting, headache, bloating, breast tenderness, swelling of the ankles/feet (fluid retention), or weight change may occur. You may also experience vaginal bleeding between periods (spotting) or missed/irregular periods, especially during the first few months of use."

Answered by AI

Does Yasmin cause weight?

"Weight gain is not a common side effect of Yasmin. Although weight changes may be a side effect of birth control pills in general, you are not likely to gain weight with Yasmin."

Answered by AI

What is Yasmin pill used for?

"The Yasmin contraceptive pill is used to prevent pregnancy by containing a small amount of two different female hormones, drospirenone and ethinylestradiol. This pill is a "combination" pill as it contains two hormones."

Answered by AI

Clinical Trials for Yasmin

Image of Erevna Innovations Inc. in Montreal, Canada.

Sculptra + Restylane for Post-Menopausal Skin Concerns

40 - 65
Female
Montreal, Canada
The post-menopausal state is marked by a sharp decline in estrogen, leading to significant structural and functional changes in the skin, including collagen loss, dryness, thinning, and reduced elasticity. To address these concerns, aesthetic injectables products such as Sculptra® Aesthetic (poly-L-lactic-acid \[PLLA- SCA\]) and Restylane Skinboosters®\[HASBV\] (small-particle hyaluronic acid - SP-HA) can be used. PLLA-SCA stimulates collagen production via cellular activation (biostimulator), gradually improving dermal structure. HASBV enhances hydration, elasticity, and skin texture when injected under the skin. Considering that hydration and laxity represent the primary aesthetic concerns in this patient population. Targeted treatment with SP-HA (HASBV) to improve hydration and PLLA-SCA to address laxity have been shown to produce significant clinical outcomes by directly addressing these key dermal deficiencies. This approach forms the basis of the current study.
Phase 4
Recruiting
Erevna Innovations Inc.Andreas Nikolis, MD, PhD
Have you considered Yasmin clinical trials? We made a collection of clinical trials featuring Yasmin, we think they might fit your search criteria.Go to Trials
Image of University of California, San Diego in La Jolla, United States.

Lidocaine for Pain Control in Birth Control

18 - 50
Female
La Jolla, CA
The goal of this research study is to learn more about how different uses of a numbing medication might affect pain levels while getting an IUD placed. The investigators are also studying participants opinions of their clinicians' empathy. The investigators are inviting patients who arrive at their clinic visit seeking an IUD. Usually, at University of California, San Diego (UCSD), for patients who have never delivered a baby, clinicians use a buffered paracervical block for before IUD placement. The purpose of this research study is to investigate whether a "buffered" (2 cc of sodium bicarbonate, 18 cc of 1% lidocaine) paracervical block (numbing medication given on both sides of the cervix) is effective in reducing pain during IUD placement in individuals with prior C-sections, the difference between buffered and unbuffered for nulliparous patients, and whether a medicated gel reduces pain with the paracervical block.
Recruiting
Paid Trial
University of California, San DiegoSheila K Mody, MD, MPH
Have you considered Yasmin clinical trials? We made a collection of clinical trials featuring Yasmin, we think they might fit your search criteria.Go to Trials
Image of Calabasas Pharmacy in Calabasas, United States.

Electronic Health Record Platform for Birth Control

18 - 51
Female
Calabasas, CA
Hormonal contraceptives are medications that require a prescription, traditionally from a physician or advanced practice provider. Over the past decade, pharmacists have gained the authority to prescribe contraceptives in many states, allowing patients to access these medications directly in pharmacies without first seeing another healthcare provider. The Pharmacist Resource to Implement Services as Modules (PRISM) is an Electronic Health Record platform designed to streamline workflows and provide clinical decision support, making it easier and safer to deliver clinical services in community pharmacies. This pilot study will evaluate patient-reported outcomes for women receiving contraceptive services from pharmacists using the PRISM platform at five community pharmacies across the United States over a 12-week period. The study will assess the quality of care, contraception continuation and failure rates, side effect rates, preventative healthcare utilization, and overall patient experience with pharmacy contraceptive services.
Waitlist Available
Has No Placebo
Calabasas Pharmacy (+4 Sites)OvaryIt, LLC
Image of Noll Laboratory in University Park, United States.

Estradiol and Elagolix for Menopause

42 - 64
Female
University Park, PA
The frequency and severity of heat waves has increased in the last decades. Older adults (over 65 years) have impaired responses to heat stress making them at increased risk for adverse events. Previous heat waves report that women over 65 experience worse health outcomes than any other age group and age matched men. Aging and reproductive hormones, specifically estrogen, independently alter responses to heat stress. However, the combined effects of low estrogen following menopause and aging on the response to heat stress are unknown. In this study, the investigators will identify the role of estrogen in pre and post menopausal women on thermoregulatory responses to heat stress.
Phase 4
Recruiting
Noll LaboratoryW. Larry Kenney, Ph.D.
Have you considered Yasmin clinical trials? We made a collection of clinical trials featuring Yasmin, we think they might fit your search criteria.Go to Trials
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