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What is Yasmin
DrospirenoneThe Generic name of this drug
Treatment SummaryDrospirenone is a synthetic progestin used in combination with ethinyl estradiol or estetrol as an oral contraceptive therapy. It is also used to treat acne and premenstrual dysphoric disorder (PMDD). There is some concern that drospirenone may increase the risk of venous thromboembolism; however, studies are conflicting and the FDA has concluded that the risk remains unclear. Generally, the risk of venous thromboembolism from using drospirenone is lower than the risk during pregnancy and postpartum.
Yasminis the brand name
Yasmin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Yasmin
Drospirenone
2001
64
Effectiveness
How Yasmin Affects PatientsDrospirenone prevents pregnancy by blocking ovulation. It may also help with acne and excess hair growth. When taken in combination with ethinyl estradiol, it has been shown to lower the levels of certain fats (lipids) in the blood. Since it is similar to natural progesterone, it is thought to cause fewer side effects such as breast tenderness and mood swings. However, drospirenone may increase the risk of developing blood clots, heart attack, or stroke. Smokers should not take this drug and those at risk of high potassium levels should avoid it as well.
How Yasmin works in the bodyDrospirenone and ethinyl estradiol work together to prevent pregnancy in several ways. They stop the release of hormones that trigger ovulation, creating a barrier to fertilization. They also make cervical mucus thicker and harder for sperm to pass through, and make it harder for a fertilized egg to implant itself. Drospirenone also has some anti-androgenic effects, blocking the effects of male hormones and helping to treat acne and hirsutism. It also reduces swelling in sebaceous follicles which can help with acne.
When to interrupt dosage
The suggested dosage of Yasmin is contingent upon the identified problem, including moderate to severe symptoms, Menopause and Post-Menarche. The amount of dosage is dependent on the technique of delivery (e.g. Tablet, film coated - Oral or Oral) as outlined in the table below.Condition
Dosage
Administration
Atrophic
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Kit - Oral, Tablet - Oral, Tablet
Atrophy of vulva
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Kit - Oral, Tablet - Oral, Tablet
Hormonal Contraception
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Kit - Oral, Tablet - Oral, Tablet
N-Cadherins
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Kit - Oral, Tablet - Oral, Tablet
moderate to severe symptoms
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Kit - Oral, Tablet - Oral, Tablet
Birth Control
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Kit - Oral, Tablet - Oral, Tablet
Acne Vulgaris
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Kit - Oral, Tablet - Oral, Tablet
Folate supplementation therapy
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Kit - Oral, Tablet - Oral, Tablet
Post-Menarche
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Kit - Oral, Tablet - Oral, Tablet
Hot flashes
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Kit - Oral, Tablet - Oral, Tablet
Vasomotor System
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Kit - Oral, Tablet - Oral, Tablet
Adherence to Oral Contraceptive Therapy
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Kit - Oral, Tablet - Oral, Tablet
Warnings
Yasmin ContraindicationsCondition
Risk Level
Notes
Chronic Kidney Disease
Do Not Combine
high risk of venous thrombotic disease
Do Not Combine
Neoplasms, Hormone-Dependent
Do Not Combine
Migraine, Classic
Do Not Combine
Porphyria
Do Not Combine
Breast
Do Not Combine
suspected pregnancy
Do Not Combine
Breast Milk Production
Do Not Combine
Metrorrhagia
Do Not Combine
Hypersensitivity
Do Not Combine
acute liver disease
Do Not Combine
Renal Insufficiency, Acute
Do Not Combine
Deep Vein Thrombosis (DVT)
Do Not Combine
Vision Loss
Do Not Combine
untreated endometrial hyperplasia
Do Not Combine
Tobacco Use
Do Not Combine
Liver Function Tests
Do Not Combine
Thrombophilia
Do Not Combine
Thromboembolism
Do Not Combine
high risk of arterial thrombotic disease
Do Not Combine
estrogen-dependent neoplasia
Do Not Combine
Neoplasms, Hepatic
Do Not Combine
Adrenal Insufficiency
Do Not Combine
recent thromboembolic event
Do Not Combine
Breast
Do Not Combine
estrogen-dependent neoplasia
Do Not Combine
Common Yasmin Drug Interactions
Drug Name
Risk Level
Description
Tranexamic acid
Major
Drospirenone may increase the thrombogenic activities of Tranexamic acid.
Acetohexamide
Minor
The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Drospirenone.
Agmatine
Minor
The risk or severity of hyperkalemia can be increased when Drospirenone is combined with Agmatine.
Aliskiren
Minor
The risk or severity of hyperkalemia can be increased when Drospirenone is combined with Aliskiren.
Anisodamine
Minor
The risk or severity of hyperkalemia can be increased when Drospirenone is combined with Anisodamine.
Yasmin Toxicity & Overdose RiskThe lowest toxic dose of drospirenone in rats has been found to be greater than 2000mg/kg. Overdosing on drospirenone may cause nausea, unusual bleeding, and changes in the levels of serum sodium and potassium. If drospirenone is overdosed, medical professionals should also check for signs of acidosis or too much potassium in the blood.
Yasmin Novel Uses: Which Conditions Have a Clinical Trial Featuring Yasmin?
104 active clinical trials are examining the possible uses of Yasmin in treating Acne Vulgaris, Post-Menarcheal states and N-Cadherin related conditions.Condition
Clinical Trials
Trial Phases
Atrophic
5 Actively Recruiting
Phase 2, Phase 4, Not Applicable
Atrophy of vulva
1 Actively Recruiting
Not Applicable
Birth Control
31 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Early Phase 1
Folate supplementation therapy
0 Actively Recruiting
Hot flashes
22 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 4, Early Phase 1
moderate to severe symptoms
0 Actively Recruiting
N-Cadherins
1 Actively Recruiting
Phase 1
Hormonal Contraception
0 Actively Recruiting
Post-Menarche
0 Actively Recruiting
Acne Vulgaris
0 Actively Recruiting
Adherence to Oral Contraceptive Therapy
0 Actively Recruiting
Vasomotor System
0 Actively Recruiting
Yasmin Reviews: What are patients saying about Yasmin?
4.3Patient Review
4/24/2020 I would not recommend this pill to anyone. It killed my best friend by causing severe blood clots and internal bleeding.
4.3Patient Review
5/23/2022 I've tried a number of different pills, and this is the only one that's managed to clear my skin within six months.
3.7Patient Review
12/9/2021 I was on this pill for seven years and I was very happy with it. The problems only appeared after I stopped taking the pill - PCOS & depression. I almost killed myself because of the overwhelming emotions, and having difficulty to get pregnant. I'm shocked nobody warned me of this side effect before, and so many women actually went through the same depression issue after the pill. If you have to use it, don't use it continuously for long periods of time.
2.7Patient Review
4/9/2022 I started taking this medication a few years ago and didn't have any adverse effects. Recently, I started again and began spotting within a few days.
2.3Patient Review
3/22/2022 This pill did what it was supposed to while I took it. However, soon after going off the pill I started losing a lot of hair, which has still not returned to normal six months later. Just wanted to give a warning to other girls considering this treatment.
2.3Patient Review
3/13/2022 Unfortunately, this medication made me really hungry all the time. As a result, I gained four kilograms in just three months. I was also constantly craving sugary and fatty foods, which isn't great for my health. On the plus side, it didn't have any negative effect on my skin.
2Patient Review
12/1/2018 This birth control pill has been the best at regulating my period and lightening it. While I did have slight nausea and breakthrough bleeding during the first month, these side effects went away by month two.
2Patient Review
7/18/2022 I had some really intolerable mood swings while taking the first pack of this medication. My period also started during the active pills, which was very inconvenient. I'm currently on my second pack and have been spotting for a few days. I've also been feeling nauseous in the morning. Overall, I would not recommend this pill to anyone.
1.7Patient Review
10/19/2022 I had a stroke at only 17 years old after starting this pill, even though there's no history of strokes in my family. Be aware that this is a possible side effect. I also started having headaches 9 months before the stroke occurred; however, they went away as soon as I stopped taking the pill.
1Patient Review
10/17/2021 Threw me into a deep depression. The pill should not be the first option for women when dealing with PCOS/ acne/ period problems, etc. There are so many other medicines or natural remedies to assist with everything; it’s a shame the health system just throws the pill at women who are struggling and calls it a day.
1Patient Review
6/1/2018 I tried this contraceptive for the first time a few weeks ago and unfortunately had some bad reactions to it. I developed pigmentation on my legs and felt incredibly itchy all over my body.
1Patient Review
9/8/2021 I had some serious heart palpitations after taking this pill for just one week. I'm glad I read the reviews before continuing- I don't want to be a statistic.
1Patient Review
4/9/2017Patient Q&A Section about yasmin
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What type of birth control is Yasmin?
"Thickening cervical mucus to keep sperm from getting to the egg
Yasmin is a combination oral contraceptive that contains a progestin and an estrogen. The progestin suppresses ovulation and the estrogen thickens cervical mucus to keep sperm from getting to the egg."
Answered by AI
Does Yasmin have side effects?
"These are some of the possible side effects of taking the birth control pill. Nausea, vomiting, headache, bloating, breast tenderness, swelling of the ankles/feet (fluid retention), or weight change may occur. You may also experience vaginal bleeding between periods (spotting) or missed/irregular periods, especially during the first few months of use."
Answered by AI
Does Yasmin cause weight?
"Weight gain is not a common side effect of Yasmin. Although weight changes may be a side effect of birth control pills in general, you are not likely to gain weight with Yasmin."
Answered by AI
What is Yasmin pill used for?
"The Yasmin contraceptive pill is used to prevent pregnancy by containing a small amount of two different female hormones, drospirenone and ethinylestradiol. This pill is a "combination" pill as it contains two hormones."
Answered by AI