Syeda

Birth Control, Acne Vulgaris, Folate supplementation therapy + 9 more
Treatment
20 Active Studies for Syeda

What is Syeda

DrospirenoneThe Generic name of this drug
Treatment SummaryDrospirenone is a synthetic progestin found in the birth control pill Yaz. It is also used with estrogens to treat acne and premenstrual dysphoric disorder (PMDD). There has been some concern that this drug may increase the risk of developing blood clots, but the FDA states that this risk remains unclear and is lower than the risk during pregnancy.
Yasminis the brand name
Syeda Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Yasmin
Drospirenone
2001
64

Effectiveness

How Syeda Affects PatientsTaking drospirenone can prevent pregnancy by stopping the maturation of follicles in the ovaries and preventing ovulation. It can also help improve acne and excessive hair growth. When combined with ethinyl estradiol, it may help improve cholesterol levels. It is similar to natural progesterone and is thought to have fewer side effects than other progesterone contraceptives, such as breast tenderness and mood swings. However, it can increase the risk of blood clots, especially in smokers and women over 35. It may also increase the risk of high potassium levels, so those at risk should not take it.
How Syeda works in the bodyDrospirenone and ethinyl estradiol work together to prevent pregnancy by blocking hormones that cause ovulation and making it harder for sperm to reach the egg. Drospirenone also helps to treat acne and hirsutism by blocking the effects of androgens, which can cause these conditions. It also reduces edema in the sebaceous follicle during the second half of the menstrual cycle, helping to prevent acne from appearing.

When to interrupt dosage

The measure of Syeda relies upon the diagnosed affliction, including moderate to severe symptoms, Menopause and Post-Menarche. The quantity likewise differs as indicated by the technique of delivery (e.g. Tablet, film coated - Oral or Oral) featured in the table beneath.
Condition
Dosage
Administration
Birth Control
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
moderate to severe symptoms
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
N-Cadherins
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
Hormonal Contraception
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
Vasomotor System
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
Acne Vulgaris
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
Adherence to Oral Contraceptive Therapy
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
Atrophic
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
Post-Menarche
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
Atrophy of vulva
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
Folate supplementation therapy
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral
Hot flashes
, 0.25 mg, 0.5 mg, 3.0 mg, 1.0 mg, 4.0 mg
, Kit, Tablet, film coated - Oral, Tablet, film coated, Oral, Kit - Oral, Tablet, Tablet - Oral

Warnings

Syeda has twenty-six contraindications, so it should not be taken when encountering any of the conditions in the table below.Syeda Contraindications
Condition
Risk Level
Notes
Chronic Kidney Disease
Do Not Combine
Venous Thrombosis
Do Not Combine
Neoplasms, Hormone-Dependent
Do Not Combine
Migraine with Aura
Do Not Combine
Porphyrias
Do Not Combine
Breast
Do Not Combine
suspected pregnancy
Do Not Combine
Breast Milk Production
Do Not Combine
Metrorrhagia
Do Not Combine
Hypersensitivity
Do Not Combine
Liver Failure, Acute
Do Not Combine
Acute Kidney Injury
Do Not Combine
Deep Vein Thrombosis (DVT)
Do Not Combine
Vision Loss
Do Not Combine
Endometrial Hyperplasia
Do Not Combine
Tobacco Use
Do Not Combine
Liver Function Tests
Do Not Combine
Thrombophilia
Do Not Combine
Thromboembolism
Do Not Combine
high risk of arterial thrombotic disease
Do Not Combine
estrogen-dependent neoplasia
Do Not Combine
Liver Neoplasms
Do Not Combine
Adrenal Insufficiency
Do Not Combine
Thrombosis
Do Not Combine
Breast
Do Not Combine
estrogen-dependent neoplasia
Do Not Combine
There are 20 known major drug interactions with Syeda.
Common Syeda Drug Interactions
Drug Name
Risk Level
Description
Tranexamic acid
Major
Drospirenone may increase the thrombogenic activities of Tranexamic acid.
Acetohexamide
Minor
The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Drospirenone.
Agmatine
Minor
The risk or severity of hyperkalemia can be increased when Drospirenone is combined with Agmatine.
Aliskiren
Minor
The risk or severity of hyperkalemia can be increased when Drospirenone is combined with Aliskiren.
Anisodamine
Minor
The risk or severity of hyperkalemia can be increased when Drospirenone is combined with Anisodamine.
Syeda Toxicity & Overdose RiskThe toxic dose of drospirenone in rats is more than 2000 mg/kg. If someone were to overdose on this drug, they may experience nausea or bleeding similar to a menstrual period. Additionally, drospirenone may cause changes in sodium and potassium levels in the blood, as well as acidosis and high potassium levels. These should be monitored if an overdose occurs.
image of a doctor in a lab doing drug, clinical research

Syeda Novel Uses: Which Conditions Have a Clinical Trial Featuring Syeda?

104 active studies are being conducted to evaluate the potential of Syeda to mitigate Acne Vulgaris, Post-Menarche and N-Cadherin-related conditions.
Condition
Clinical Trials
Trial Phases
N-Cadherins
0 Actively Recruiting
moderate to severe symptoms
0 Actively Recruiting
Folate supplementation therapy
0 Actively Recruiting
Acne Vulgaris
0 Actively Recruiting
Atrophy of vulva
1 Actively Recruiting
Not Applicable
Hormonal Contraception
0 Actively Recruiting
Hot flashes
19 Actively Recruiting
Not Applicable, Phase 4, Phase 2, Early Phase 1, Phase 3
Post-Menarche
0 Actively Recruiting
Adherence to Oral Contraceptive Therapy
0 Actively Recruiting
Birth Control
22 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Early Phase 1, Phase 2
Atrophic
4 Actively Recruiting
Phase 4, Not Applicable
Vasomotor System
0 Actively Recruiting

Syeda Reviews: What are patients saying about Syeda?

5Patient Review
5/15/2020
Syeda for Disease of Ovaries with Cysts
Syeda is extremely effective, even if you miss a couple days or have unprotected sex. I've struggled with PCOS and other brands have made me gain weight, but not Syeda.
4.3Patient Review
3/9/2019
Syeda for Acne
I've been on Syeda for a few years now and it's done wonders for my acne. However, I have noticed that I gain about 10 pounds each year while on the medication, which is something to consider if you're thinking of starting this treatment. Additionally, it hasn't had much impact on my periods.
3.7Patient Review
2/27/2020
Syeda for Birth Control
I started this treatment six weeks ago, and I have noticed a significant change in my mood. I am now grumpy and feeling tense all the time. I have also gained 10 pounds, which is very unusual for me. The side effects are just not worth it.
3.7Patient Review
12/29/2019
Syeda for Birth Control
I've now been using this treatment for two months as a form of birth control. The first few weeks, I was nauseous almost every day to the point where I considered stopping; however, I powered through it. Last month, my period was surprisingly light with hardly any cramps! This is usually not the case for me, so hopefully this trend will continue.
3.3Patient Review
4/13/2019
Syeda for Birth Control
I experienced some serious stomach pains early on, but they eventually subsided. I also found that my periods were less heavy and didn't last as long. My skin was always nice and smooth while using this medication. I feel myself hungrier than usual though not sure if it’s because of the pills or just me
3Patient Review
10/30/2022
Syeda for Birth Control
Unfortunately, I experienced significant weight gain, mood swings and acne while taking this medication. Additionally, my breasts became quite tender.
2.3Patient Review
9/20/2022
Syeda for Acne
While this birth control did help with my acne and functioned as intended, the side effects were really tough to deal with. My anxiety was through the roof and I became very depressed. Once I stopped taking it, naturally I started to feel better.
2Patient Review
4/25/2020
Syeda for Birth Control
I switched birth controls back in January and started taking Syeda then. My weight has gone up noticeably, as well as my breast size (two cup sizes). I'm constantly moody and bloated, no matter what. I'll be switching birth controls very soon; Syeda just doesn't work for me.
1.7Patient Review
7/12/2022
Syeda for Disease of Ovaries with Cysts
Bloating and general discomfort were my experience with this product. It took a little while to figure out that it was the birth control, but once I stopped taking it those symptoms went away.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about syeda

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are Yasmin and Syeda the same?

"The FDA approved a generic form of Yasmin called Syeda in June 2011 for the prevention of pregnancy. Syeda is an oral contraceptive distributed by Sandoz, Inc., and it belongs to the "fourth generation" of birth control pills that contain drospirenone."

Answered by AI

What are the side effects of Syeda?

"If you experience any of these side effects, contact your doctor

The following side effects may occur: nausea, vomiting, headache, bloating, breast tenderness, swelling of the ankles/feet (fluid retention), or weight change. You may also experience vaginal bleeding between periods (spotting) or missed/irregular periods, especially during the first few months of use. If you experience any of these side effects, contact your doctor."

Answered by AI

Does Syeda cause weight gain?

"This should theoretically reduce bloating and water weight.

Does Syeda cause weight gain?

Very few women experience weight gain when taking Syeda. Syeda has a theoretical diuretic effect, meaning it helps shed water from the body. This should theoretically reduce bloating and water weight."

Answered by AI

What is Syeda generic for?

"Syeda is a generic oral contraceptive that contains a combination of estrogen and progestin. It is indicated for use by women to prevent pregnancy."

Answered by AI

Clinical Trials for Syeda

Image of Erevna Innovations Inc. in Montreal, Canada.

Sculptra + Restylane for Post-Menopausal Skin Concerns

40 - 65
Female
Montreal, Canada
The post-menopausal state is marked by a sharp decline in estrogen, leading to significant structural and functional changes in the skin, including collagen loss, dryness, thinning, and reduced elasticity. To address these concerns, aesthetic injectables products such as Sculptra® Aesthetic (poly-L-lactic-acid \[PLLA- SCA\]) and Restylane Skinboosters®\[HASBV\] (small-particle hyaluronic acid - SP-HA) can be used. PLLA-SCA stimulates collagen production via cellular activation (biostimulator), gradually improving dermal structure. HASBV enhances hydration, elasticity, and skin texture when injected under the skin. Considering that hydration and laxity represent the primary aesthetic concerns in this patient population. Targeted treatment with SP-HA (HASBV) to improve hydration and PLLA-SCA to address laxity have been shown to produce significant clinical outcomes by directly addressing these key dermal deficiencies. This approach forms the basis of the current study.
Phase 4
Recruiting
Erevna Innovations Inc.Andreas Nikolis, MD, PhD
Have you considered Syeda clinical trials? We made a collection of clinical trials featuring Syeda, we think they might fit your search criteria.Go to Trials
Image of University of California, San Diego in La Jolla, United States.

Lidocaine for Pain Control in Birth Control

18 - 50
Female
La Jolla, CA
The goal of this research study is to learn more about how different uses of a numbing medication might affect pain levels while getting an IUD placed. The investigators are also studying participants opinions of their clinicians' empathy. The investigators are inviting patients who arrive at their clinic visit seeking an IUD. Usually, at University of California, San Diego (UCSD), for patients who have never delivered a baby, clinicians use a buffered paracervical block for before IUD placement. The purpose of this research study is to investigate whether a "buffered" (2 cc of sodium bicarbonate, 18 cc of 1% lidocaine) paracervical block (numbing medication given on both sides of the cervix) is effective in reducing pain during IUD placement in individuals with prior C-sections, the difference between buffered and unbuffered for nulliparous patients, and whether a medicated gel reduces pain with the paracervical block.
Recruiting
Paid Trial
University of California, San DiegoSheila K Mody, MD, MPH
Have you considered Syeda clinical trials? We made a collection of clinical trials featuring Syeda, we think they might fit your search criteria.Go to Trials
Image of Calabasas Pharmacy in Calabasas, United States.

Electronic Health Record Platform for Birth Control

18 - 51
Female
Calabasas, CA
Hormonal contraceptives are medications that require a prescription, traditionally from a physician or advanced practice provider. Over the past decade, pharmacists have gained the authority to prescribe contraceptives in many states, allowing patients to access these medications directly in pharmacies without first seeing another healthcare provider. The Pharmacist Resource to Implement Services as Modules (PRISM) is an Electronic Health Record platform designed to streamline workflows and provide clinical decision support, making it easier and safer to deliver clinical services in community pharmacies. This pilot study will evaluate patient-reported outcomes for women receiving contraceptive services from pharmacists using the PRISM platform at five community pharmacies across the United States over a 12-week period. The study will assess the quality of care, contraception continuation and failure rates, side effect rates, preventative healthcare utilization, and overall patient experience with pharmacy contraceptive services.
Waitlist Available
Has No Placebo
Calabasas Pharmacy (+4 Sites)OvaryIt, LLC
Image of Noll Laboratory in University Park, United States.

Estradiol and Elagolix for Menopause

42 - 64
Female
University Park, PA
The frequency and severity of heat waves has increased in the last decades. Older adults (over 65 years) have impaired responses to heat stress making them at increased risk for adverse events. Previous heat waves report that women over 65 experience worse health outcomes than any other age group and age matched men. Aging and reproductive hormones, specifically estrogen, independently alter responses to heat stress. However, the combined effects of low estrogen following menopause and aging on the response to heat stress are unknown. In this study, the investigators will identify the role of estrogen in pre and post menopausal women on thermoregulatory responses to heat stress.
Phase 4
Recruiting
Noll LaboratoryW. Larry Kenney, Ph.D.
Have you considered Syeda clinical trials? We made a collection of clinical trials featuring Syeda, we think they might fit your search criteria.Go to Trials
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