Marlissa

Birth Control, Acne Vulgaris, Folate supplementation therapy + 5 more
Treatment
1 FDA approval
20 Active Studies for Marlissa

What is Marlissa

EthinylestradiolThe Generic name of this drug
Treatment SummaryEthinylestradiol is a synthetic form of the female hormone estrogen. It was created in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering to give better results when taken orally. Ethinylestradiol was approved by the FDA in 1943 and is used in contraceptive pills as a replacement for mestranol.
LOESTRIN Fe 1.5/30is the brand name
Marlissa Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
LOESTRIN Fe 1.5/30
Ethinylestradiol
1973
679

Approved as Treatment by the FDA

Ethinylestradiol, also known as LOESTRIN Fe 1.5/30, is approved by the FDA for 1 uses including Birth Control .
Birth Control
Used to treat Contraception in combination with Levonorgestrel

Effectiveness

How Marlissa Affects PatientsEthinylestradiol is a synthetic form of estrogen that helps to regulate the hormones that trigger ovulation and the growth of the uterus lining. Taking the drug once per day typically results in long-lasting effects, and it is considered to be a safe medication with few serious side effects. However, patients should be aware of the potential for increased risks of blood clots.
How Marlissa works in the bodyEthinylestradiol is a synthetic form of estrogen. It has several effects on the body, including reducing bone density. When taken as a contraceptive, it stops ovulation by stopping hormones that create eggs. It also thickens cervical mucus and prevents changes in the uterus that would allow a fertilized egg to implant. Additionally, it decreases the luteinizing hormone which decreases blood flow to the uterus, and increases sex hormone binding globulin.

When to interrupt dosage

The prescribed dosage of Marlissa is contingent upon the diagnosed condition, for example Acne Vulgaris, Hormonal Contraception and Folate supplementation therapy. Dosage depends on the technique of application delineated in the attached table.
Condition
Dosage
Administration
Birth Control
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Mild to Moderate Acne
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Menopausal Osteoporosis
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Patient desires oral contraception for birth control
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Acne Vulgaris
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Folate supplementation therapy
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Hormonal Contraception
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Menopause
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral

Warnings

Marlissa has twenty-six counter-indications. It should not be taken in combination with the ailments indicated in the following table.Marlissa Contraindications
Condition
Risk Level
Notes
Heavy Smoking
Do Not Combine
Metrorrhagia
Do Not Combine
estrogen-sensitive cancer
Do Not Combine
Thrombophlebitis
Do Not Combine
high risk of venous thrombotic disease
Do Not Combine
history of deep venous thrombosis
Do Not Combine
Pulse Frequency
Do Not Combine
Breast
Do Not Combine
Coronary Artery Disease
Do Not Combine
high risk of arterial thrombotic disease
Do Not Combine
Thromboembolism
Do Not Combine
Coronary Artery Disease (CAD)
Do Not Combine
Hypersensitivity
Do Not Combine
Pulse Frequency
Do Not Combine
Adrenal Insufficiency
Do Not Combine
major surgery with prolonged immobilization
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypertension
Do Not Combine
undiagnosed abnormal genital bleeding
Do Not Combine
Breast Cancer
Do Not Combine
Neoplasms, Hepatic
Do Not Combine
Deep Vein Thrombosis
Do Not Combine
Decompensated Cirrhosis
Do Not Combine
Breast
Do Not Combine
Impaired Renal Function
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Ethinylestradiol may interact with Pulse Frequency
There are 20 known major drug interactions with Marlissa.
Common Marlissa Drug Interactions
Drug Name
Risk Level
Description
Anastrozole
Major
The therapeutic efficacy of Anastrozole can be decreased when used in combination with Ethinylestradiol.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Ethinylestradiol.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Ethinylestradiol.
Belinostat
Major
The metabolism of Belinostat can be increased when combined with Ethinylestradiol.
Binimetinib
Major
The metabolism of Binimetinib can be increased when combined with Ethinylestradiol.
Marlissa Toxicity & Overdose RiskWomen who have taken too much of this drug may experience bleeding, nausea, vomiting, sore breasts, abdominal pain, drowsiness, and exhaustion. Treatment for an overdose should include monitoring for potassium and sodium levels as well as signs of metabolic acidosis, along with providing supportive care.
image of a doctor in a lab doing drug, clinical research

Marlissa Novel Uses: Which Conditions Have a Clinical Trial Featuring Marlissa?

38 active clinical trials are currently evaluating the possible benefits of Marlissa for Folate supplementation therapy, Premenstrual Dysphoric Disorder and Menopausal symptoms.
Condition
Clinical Trials
Trial Phases
Birth Control
31 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Early Phase 1
Patient desires oral contraception for birth control
0 Actively Recruiting
Folate supplementation therapy
0 Actively Recruiting
Hormonal Contraception
0 Actively Recruiting
Mild to Moderate Acne
0 Actively Recruiting
Menopausal Osteoporosis
0 Actively Recruiting
Menopause
0 Actively Recruiting
Acne Vulgaris
0 Actively Recruiting

Marlissa Reviews: What are patients saying about Marlissa?

5Patient Review
8/12/2016
Marlissa for Abnormally Long or Heavy Periods
Marlissa quickly and effectively alleviated the pain I was experiencing from my heavy periods.
5Patient Review
2/24/2016
Marlissa for Birth Control
I switched to Marlissa from another generic brand of Nordette, Levora, about two years ago. I've had no issues with the pill; it's small and easy to take. My periods are light and last only three days. There's no cramping, just some occasional headaches and bloating from PMS. I also haven't experienced any weight gain or crazy breakouts, enlarged breasts, etc. All in all, this is a great low-dose birth control option that does what it's supposed to do.
4.7Patient Review
6/3/2018
Marlissa for Abnormally Long or Heavy Periods
At first, this medication really threw me for a loop with some intense mood swings. However, after about three weeks those subsided. I'm now two months in and while my blackheads have gotten worse, thankfully the moodiness is gone.
4.7Patient Review
5/25/2016
Marlissa for Birth Control
I've tried a lot of different birth control pills, and this one is by far the best. My periods have been extremely regular, down to the hour, and they're lighter now too. They only last for around three days. The only downside is that I get headaches two days before my period starts, and they last for two days into my period.
4.3Patient Review
3/14/2015
Marlissa for Birth Control
This was a really easy and straightforward treatment.
4Patient Review
9/14/2017
Marlissa for Birth Control
So far, no unplanned pregnancies. My periods are still about the same length, but they only last 4-5 days now which is an improvement. I have more water retention than usual, making weight loss difficult; however, this may just be a side effect that goes away with time. Additionally, my mood has been more stable since starting this medication.
3.3Patient Review
11/1/2016
Marlissa for Abnormally Long or Heavy Periods
I had some unfortunate side effects while using this medication, including sudden sweats, stomach pain and headaches. However, my period did become regular which was the intended goal.
2.7Patient Review
3/29/2022
Marlissa for Painful Periods
I became extremely bloated and uncomfortable to the point of pain while taking this medication. My mood swings also intensified, leading to depression and anxiety. Needless to say, I stopped taking it within a few weeks.
2.3Patient Review
7/6/2016
Marlissa for Birth Control
I gained ten pounds of water weight in just over a month while taking this medication. I didn't notice any changes in my mood, although I did become more depressed at times mostly due to the extreme weight gain.
2.3Patient Review
5/19/2015
Marlissa for Birth Control
I felt more moody and depressed while on this medication, and my periods became irregular. I also had more headaches than usual.
2.3Patient Review
12/17/2013
Marlissa for Endometriosis
1.7Patient Review
2/25/2018
Marlissa for Birth Control
I experienced some very concerning mood swings while taking this medicine. I would never normally speak to myself with such hatred, but after being on the medication for a while, it became almost impossible to control. It was effective in that I didn't get pregnant; however, the negative effects were not worth it.
1Patient Review
6/23/2015
Marlissa for Birth Control
The side effects were really bad. I had a lot of pain in my feet and my blood pressure spiked.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about marlissa

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does marlissa birth control make you gain weight?

"While some women worry about weight gain when taking Marlissa and other birth control pills, the weight gain is mostly due to water retention and not actual fat."

Answered by AI

What are the side effects of marlissa?

"The following side effects may occur: nausea, vomiting, headache, bloating, breast tenderness, swelling of the ankles/feet (fluid retention), or weight change. Vaginal bleeding between periods (spotting) or missed/irregular periods may occur, especially during the first few months of use."

Answered by AI

What is marlissa generic for?

"Levonorgestrel and ethinyl estradiol tablets (0.15 mg/0.03 mg) are an oral contraceptive indicated for the prevention of pregnancy in women who elect to use this product as a method of contraception. Levonorgestrel and ethinyl estradiol tablets are available in generic form."

Answered by AI

Is marlissa a good birth control?

"Overall, it was a good experience and I would recommend it.”

I was on Marlissa for two months and found it to be a good birth control pill. My periods were light and short, and I had an increased appetite at times, but I was able to offset this with exercise and a healthy diet. Overall, I would recommend it."

Answered by AI

Clinical Trials for Marlissa

Have you considered Marlissa clinical trials? We made a collection of clinical trials featuring Marlissa, we think they might fit your search criteria.
Have you considered Marlissa clinical trials? We made a collection of clinical trials featuring Marlissa, we think they might fit your search criteria.
Have you considered Marlissa clinical trials? We made a collection of clinical trials featuring Marlissa, we think they might fit your search criteria.
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