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Intra-abdominal sepsis for Sepsis

N/A

Waitlist Available

Led By Philip Efron, MD

Research Sponsored by University of Florida

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to one year

Awards & highlights

Study Summary

This trial will help researchers understand more about what happens to patients after they experience sepsis, specifically those who develop chronic critical illness.

Who is the study for?

This trial is for adults over 18 who are in the surgical or trauma ICU with a diagnosis of sepsis, severe sepsis, or septic shock. They must be part of the standard-care sepsis protocol and able to give consent themselves or through a legal representative.Check my eligibility

What is being tested?

The study aims to understand how serious abdominal infections affect frailty, existing health conditions, and daily function. It involves measuring frailty levels, leisure activities impact on health, body muscle mass via CT scans, and mobility tracking.See study design

What are the potential side effects?

Since this trial focuses on observations rather than treatments or medications, there are no direct side effects from interventions being tested. However, monitoring may involve some discomfort due to wearing devices or undergoing scans.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to one year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to one year

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to one year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

A change in rate of participants (0-100%) that meet frailty consensus criteria comparing baseline score to assessments after (3, 6, 12 months) episode of intra-abdominal sepsis using the Fried Frailty Criteria.

Secondary outcome measures

A change in mobility and activity from hospitalization to the one year mark.

A change in the Modified Minnesota leisure time activities questionnaire from baseline to the one year mark.

Change in measurement of torso sarcopenia.

+1 more

Trial Design

1Treatment groups

Experimental Treatment

Group I: Intra-abdominal sepsisExperimental Treatment4 Interventions

Frailty measurements. Modified Minnesota Leisure Time Activities. Computed tomography morphometrics. Mobility Monitors.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

National Institute on Aging (NIA)NIH

1,668 Previous Clinical Trials

28,005,011 Total Patients Enrolled

2 Trials studying Sepsis

352 Patients Enrolled for Sepsis

University of FloridaLead Sponsor

1,340 Previous Clinical Trials

715,643 Total Patients Enrolled

20 Trials studying Sepsis

7,694 Patients Enrolled for Sepsis

National Institutes of Health (NIH)NIH

2,696 Previous Clinical Trials

6,952,535 Total Patients Enrolled

13 Trials studying Sepsis

9,691 Patients Enrolled for Sepsis

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any available spots to join this investigation?

"Information hosted on clinicaltrials.gov alludes to the fact that this medical study is no longer recruiting participants, with its initial post and last update being April 1st 2016 and February 11th 2021 respectively. Despite this, there are still 656 other trials actively looking for patients at present."

Answered by AI

What is the primary purpose of this experiment?

"This trial is set to be evaluated over the course of Baseline, 3, 6 and 12 months. Its primary goal is to assess a change in rate of participants (0-100%) conforming with frailty consensus criteria starting from their baseline score up until assessments after intra-abdominal sepsis using Fried Frailty Criteria. Secondary objectives include an alteration in Modified Minnesota leisure time activities questionnaire's results between baseline and one year mark; this measures both free time as well as domestic chores for two weeks prior to hospitalization and at each previously stated point in time via indexed activity intensity codes used to calculate Activity Metabolic Index -"

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS): A New Horizon for Surgical Critical Care and Induced Frailty

2016. "Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS): A New Horizon for Surgical Critical Care and Induced Frailty". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02711709.