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Procedure

Weight-Loss Surgery vs Medical Management for Diabetes (REMISSION Trial)

N/A
Waitlist Available
Research Sponsored by Laval University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Diagnosis of type 2 diabetes
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline up to 60 months
Awards & highlights

REMISSION Trial Summary

This trial is studying the long-term effects of 3 different weight-loss surgeries on diabetes, kidney, and heart health in obese patients with diabetes.

Who is the study for?
This trial is for individuals with type 2 diabetes, an HbA1c ≥ 6.5%, fasting glycemia ≥ 7mmol/l or non-fasting glycemia ≥ 11mmol/l, and a BMI ≥ 35 who can consent to participate. It excludes those with recent substance abuse, pregnancy, certain gastrointestinal diseases, prior gastric surgeries, severe organ disease, corticosteroid use in the last month, or psychological issues affecting compliance.Check my eligibility
What is being tested?
The REMISSION trial is studying the long-term effects of three bariatric surgery types (RYGB, SG & BPD-DS) on metabolic recovery and quality of life compared to best medical management in diabetic patients. The goal is to understand which procedure might be most beneficial for treating type 2 diabetes.See study design
What are the potential side effects?
Potential side effects from these surgeries include nutritional deficiencies due to malabsorption, surgical complications like infections or bleeding, changes in bowel habits such as diarrhea or constipation and possible need for reoperation.

REMISSION Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I have been diagnosed with type 2 diabetes.

REMISSION Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline up to 60 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline up to 60 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Type 2 diabetes remission rate
Secondary outcome measures
Change in microalbuminuria
Change in retinopathy
Dislipidemia remission
+6 more
Other outcome measures
Long-term complications
short-term complications

REMISSION Trial Design

4Treatment groups
Active Control
Group I: ControlActive Control1 Intervention
the best medical management of their diabetes, non-surgical group
Group II: Roux-en-Y Gastric BypassActive Control1 Intervention
Group III: Biliopancreatic DiversionActive Control1 Intervention
Group IV: Sleeve gastrectomyActive Control1 Intervention

Find a Location

Who is running the clinical trial?

Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de QuebecOTHER
36 Previous Clinical Trials
9,334 Total Patients Enrolled
Laval UniversityLead Sponsor
416 Previous Clinical Trials
171,868 Total Patients Enrolled
3 Trials studying Bariatric Surgery Candidates
10,040 Patients Enrolled for Bariatric Surgery Candidates
Johnson & Johnson Medical ProductsUNKNOWN

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Am I eligible to participate in this health study?

"In order to be admitted into this research, participants must have undergone bariatric surgery and fall within the age bracket of 18-60. The research is expecting to recruit 408 people in total."

Answered by AI

What is the capacity of participants for this experiment?

"Correct. According to clinicaltrials.gov, this medical trial has been running since its initial posting on March 1st 2015 and is actively searching for participants with an estimated need of 408 patients from one location."

Answered by AI

Is it still possible to join this research trial?

"This clinical trial, whose post date can be found on clinicaltrials.gov as March 1st 2015, is currently attempting to secure participants. It was most recently adjusted on February 17th 2021."

Answered by AI

Are those aged 55 and beyond accepted into this research initiative?

"In order to be enrolled in this clinical trial, participants must meet the minimum age requirement of 18 and not exceed 60 years old."

Answered by AI
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~41 spots leftby Mar 2025