Vagistat-1

Onychomycosis, Inflammation, Cellulitis + 5 more
Treatment
20 Active Studies for Vagistat-1

What is Vagistat-1

TioconazoleThe Generic name of this drug
Treatment SummaryTioconazole is a medication used to treat fungal and yeast infections. It comes in topical formulations which can be used to treat common skin infections like ringworm, jock itch, athlete's foot, and sun fungus. Tioconazole works by blocking the production of an important component of the yeast cell membrane, leading to increased permeability and ultimately killing the fungus.
Vagistat-1is the brand name
Vagistat-1 Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Vagistat-1
Tioconazole
1997
32

Effectiveness

How Vagistat-1 Affects PatientsTioconazole is a medication used to fight fungal yeast infections. It kills or stops the growth of fungi like Candida albicans and Torulopsis glabrata. Tioconazole works by blocking the production of substances needed to keep fungi cells alive. It won't work for illnesses caused by bacteria or viruses.
How Vagistat-1 works in the bodyTioconazole works by stopping a specific enzyme from making the molecule ergosterol, which is needed in the cell membrane of yeast. When this molecule isn't present, the yeast cell becomes more permeable. Tioconazole can also have other effects on the yeast, such as inhibiting respiration, blocking the movement of calcium and potassium ions, and preventing the yeast from changing into its fungal form.

When to interrupt dosage

The endorsed dose of Vagistat-1 is contingent upon the acknowledged condition, including Vulvovaginal Candidiasis, cutaneous dermatophyte infection and Infection, Mixed. The quantity of dosage deviates, in accordance with the administration technique (e.g. Ointment - Vaginal or Topical) featured in the table beneath.
Condition
Dosage
Administration
Onychomycosis
300.0 mg, , 0.065 mg/mg, 0.3 mg/mg, 6.5 %, 1.0 %, 7.5 %, 0.01 mg/mg
, Ointment, Ointment - Vaginal, Vaginal, Topical, Ointment - Topical, Suppository, Cream, Suppository - Vaginal, Cream - Topical, Topical; Vaginal, Cream; Ointment, Cream; Ointment - Topical; Vaginal, Cream; Suppository, Cream; Suppository - Topical; Vaginal
Coinfection
300.0 mg, , 0.065 mg/mg, 0.3 mg/mg, 6.5 %, 1.0 %, 7.5 %, 0.01 mg/mg
, Ointment, Ointment - Vaginal, Vaginal, Topical, Ointment - Topical, Suppository, Cream, Suppository - Vaginal, Cream - Topical, Topical; Vaginal, Cream; Ointment, Cream; Ointment - Topical; Vaginal, Cream; Suppository, Cream; Suppository - Topical; Vaginal
Cellulitis
300.0 mg, , 0.065 mg/mg, 0.3 mg/mg, 6.5 %, 1.0 %, 7.5 %, 0.01 mg/mg
, Ointment, Ointment - Vaginal, Vaginal, Topical, Ointment - Topical, Suppository, Cream, Suppository - Vaginal, Cream - Topical, Topical; Vaginal, Cream; Ointment, Cream; Ointment - Topical; Vaginal, Cream; Suppository, Cream; Suppository - Topical; Vaginal
Candidiasis, Vulvovaginal
300.0 mg, , 0.065 mg/mg, 0.3 mg/mg, 6.5 %, 1.0 %, 7.5 %, 0.01 mg/mg
, Ointment, Ointment - Vaginal, Vaginal, Topical, Ointment - Topical, Suppository, Cream, Suppository - Vaginal, Cream - Topical, Topical; Vaginal, Cream; Ointment, Cream; Ointment - Topical; Vaginal, Cream; Suppository, Cream; Suppository - Topical; Vaginal
Tinea Pedis
300.0 mg, , 0.065 mg/mg, 0.3 mg/mg, 6.5 %, 1.0 %, 7.5 %, 0.01 mg/mg
, Ointment, Ointment - Vaginal, Vaginal, Topical, Ointment - Topical, Suppository, Cream, Suppository - Vaginal, Cream - Topical, Topical; Vaginal, Cream; Ointment, Cream; Ointment - Topical; Vaginal, Cream; Suppository, Cream; Suppository - Topical; Vaginal
cutaneous dermatophyte infection
300.0 mg, , 0.065 mg/mg, 0.3 mg/mg, 6.5 %, 1.0 %, 7.5 %, 0.01 mg/mg
, Ointment, Ointment - Vaginal, Vaginal, Topical, Ointment - Topical, Suppository, Cream, Suppository - Vaginal, Cream - Topical, Topical; Vaginal, Cream; Ointment, Cream; Ointment - Topical; Vaginal, Cream; Suppository, Cream; Suppository - Topical; Vaginal
Candidiasis, Vulvovaginal
300.0 mg, , 0.065 mg/mg, 0.3 mg/mg, 6.5 %, 1.0 %, 7.5 %, 0.01 mg/mg
, Ointment, Ointment - Vaginal, Vaginal, Topical, Ointment - Topical, Suppository, Cream, Suppository - Vaginal, Cream - Topical, Topical; Vaginal, Cream; Ointment, Cream; Ointment - Topical; Vaginal, Cream; Suppository, Cream; Suppository - Topical; Vaginal
Inflammation
300.0 mg, , 0.065 mg/mg, 0.3 mg/mg, 6.5 %, 1.0 %, 7.5 %, 0.01 mg/mg
, Ointment, Ointment - Vaginal, Vaginal, Topical, Ointment - Topical, Suppository, Cream, Suppository - Vaginal, Cream - Topical, Topical; Vaginal, Cream; Ointment, Cream; Ointment - Topical; Vaginal, Cream; Suppository, Cream; Suppository - Topical; Vaginal

Warnings

There are 20 known major drug interactions with Vagistat-1.
Common Vagistat-1 Drug Interactions
Drug Name
Risk Level
Description
Cariprazine
Major
The metabolism of Cariprazine can be decreased when combined with Tioconazole.
Eliglustat
Major
The metabolism of Eliglustat can be decreased when combined with Tioconazole.
Entrectinib
Major
The metabolism of Entrectinib can be decreased when combined with Tioconazole.
Fentanyl
Major
The metabolism of Fentanyl can be decreased when combined with Tioconazole.
Infigratinib
Major
The metabolism of Infigratinib can be decreased when combined with Tioconazole.
Vagistat-1 Toxicity & Overdose RiskOverdosing on the drug can cause redness, stinging, blistering, swelling, itching, hives, burning, and general skin irritation, as well as cramps.
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Vagistat-1 Novel Uses: Which Conditions Have a Clinical Trial Featuring Vagistat-1?

191 separate studies are currently being conducted to explore Vagistat-1's potential to mitigate cutaneous dermatophyte infection, superficial Fungal skin infection and Communicable Diseases.
Condition
Clinical Trials
Trial Phases
Candidiasis, Vulvovaginal
2 Actively Recruiting
Early Phase 1
Inflammation
66 Actively Recruiting
Not Applicable, Early Phase 1, Phase 1, Phase 2, Phase 3, Phase 4
cutaneous dermatophyte infection
0 Actively Recruiting
Cellulitis
0 Actively Recruiting
Tinea Pedis
0 Actively Recruiting
Onychomycosis
0 Actively Recruiting
Coinfection
0 Actively Recruiting
Candidiasis, Vulvovaginal
0 Actively Recruiting

Vagistat-1 Reviews: What are patients saying about Vagistat-1?

5Patient Review
4/28/2014
Vagistat-1 for Yeast Infection of Vagina and Vulva
This was much more effective than Monistat, and the itching wasn't nearly as bad.
5Patient Review
2/7/2022
Vagistat-1 for Yeast Infection of Vagina and Vulva
This treatment completely knocked out all of my symptoms overnight! I woke up feeling normal again. Some people might be more sensitive to this product, but it worked great for me even though I'm usually quite sensitive.
4.3Patient Review
4/13/2022
Vagistat-1 for Yeast Infection of Vagina and Vulva
I'm only a couple hours into using this, but so far it's been much better than Monistat in terms of burning and itching.
3.3Patient Review
9/3/2022
Vagistat-1 for Yeast Infection of Vagina and Vulva
I'm trying this brand for the first time and chose the Vagistat 1 because I wanted to avoid leakage for more than a week. After insertion, I felt burning which is something I expected. It's not too bad though. So far, so good. I'll update my review once I know more about what's going on.
2.7Patient Review
4/25/2022
Vagistat-1 for Yeast Infection of Vagina and Vulva
The burning and pain was unbearable. My vulva was so swollen, it hurt to walk. I have chronic infections, so I'm used to calling and getting fluconazole. Since it was a Sunday, I decided to try this treatment instead. Big mistake.
View All Reviews
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Patient Q&A Section about vagistat-1

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How effective is vagistat?

"Vagistat-1 has an average rating of 6.5 from 18 ratings for the treatment of Vaginal Yeast infection. 50% reported a positive experience, while 22% reported a negative experience."

Answered by AI

How long does vagistat-1 take to work?

"If you use the one-day treatment, you should start seeing some improvement in your symptoms within a day. However, it may take up to a week for your symptoms to completely go away."

Answered by AI

Are vagistat and MONISTAT the same?

"Vagisil will help relieve itching, but it does not contain an antifungal to help the source of the infection. There is a product called Vagistat, from the manufacturers of Vagisil, which contains miconazole in an internal and external cream and is similar to Monistat 3."

Answered by AI

Does vagistat cure yeast infection?

"This drug is used to treat vaginal yeast infections. Miconazole decreases vaginal irritation, itching, and discharge that may happen with this condition. This drug is an azole antifungal. It works by preventing the growth of yeast (fungus) that causes the infection."

Answered by AI

Clinical Trials for Vagistat-1

Have you considered Vagistat-1 clinical trials? We made a collection of clinical trials featuring Vagistat-1, we think they might fit your search criteria.
Have you considered Vagistat-1 clinical trials? We made a collection of clinical trials featuring Vagistat-1, we think they might fit your search criteria.
Have you considered Vagistat-1 clinical trials? We made a collection of clinical trials featuring Vagistat-1, we think they might fit your search criteria.
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