Wixela Inhub

Asthma, Chronic Obstructive Pulmonary Disease, Bronchospasm, Exercise-Induced + 1 more
Treatment
4 FDA approvals
20 Active Studies for Wixela Inhub

What is Wixela Inhub

SalmeterolThe Generic name of this drug
Treatment SummaryFluticasone propionate is a drug used to treat inflammation. It is available as an inhaler, nasal spray, topical ointment, or cream. Fluticasone propionate was approved in 1990 and is commonly used to treat various inflammatory conditions.
Serevent Diskusis the brand name
image of different drug pills on a surface
Wixela Inhub Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Serevent Diskus
Salmeterol
1997
77

Approved as Treatment by the FDA

Salmeterol, otherwise called Serevent Diskus, is approved by the FDA for 4 uses including Chronic Obstructive Pulmonary Disease and Asthma .
Chronic Obstructive Pulmonary Disease
Helps manage Chronic Obstructive Pulmonary Disease (COPD)
Asthma
Used to treat Asthma in combination with Fluticasone propionate
Exercise-Induced Bronchospasm
Bronchospasm, Exercise-Induced

Effectiveness

How Wixela Inhub Affects PatientsWhen taken internally, fluticasone propionate works by activating certain receptors in the body and decreasing the number of eosinophils (a type of white blood cell) in the lungs. When applied topically, fluticasone propionate can cause the blood vessels in the skin to become narrower.
How Wixela Inhub works in the bodyFluticasone propionate has an unknown mechanism of action, but it is thought to reduce inflammation by targeting cell types and mediators. It can also activate specific receptors and reduce eosinophilia in the lungs of rats.

When to interrupt dosage

The proposed dosage of Wixela Inhub is contingent upon the indicated condition, comprising Sinusitis, Chronic Obstructive Pulmonary Disease (COPD) and Non-Allergic Rhinitis. The quantity of dosage fluctuates, as per the technique of delivery (e.g. Spray, metered - Nasal or Respiratory (inhalation)) featured in the following table.
Condition
Dosage
Administration
Exercise-Induced Bronchospasm
, 0.05 mg, 0.021 mg, 0.014 mg, 0.05 mg/pump actuation, 0.014 mg/pump actuation, 0.025 mg/pump actuation, 0.01275 mg
, Oral; Respiratory (inhalation), Powder, metered, Powder, metered - Oral; Respiratory (inhalation), Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Powder - Oral; Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Aerosol, Aerosol - Respiratory (inhalation)
Asthma
, 0.05 mg, 0.021 mg, 0.014 mg, 0.05 mg/pump actuation, 0.014 mg/pump actuation, 0.025 mg/pump actuation, 0.01275 mg
, Oral; Respiratory (inhalation), Powder, metered, Powder, metered - Oral; Respiratory (inhalation), Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Powder - Oral; Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Aerosol, Aerosol - Respiratory (inhalation)
Chronic Obstructive Pulmonary Disease
, 0.05 mg, 0.021 mg, 0.014 mg, 0.05 mg/pump actuation, 0.014 mg/pump actuation, 0.025 mg/pump actuation, 0.01275 mg
, Oral; Respiratory (inhalation), Powder, metered, Powder, metered - Oral; Respiratory (inhalation), Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Powder - Oral; Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Aerosol, Aerosol - Respiratory (inhalation)
Bronchospasm, Exercise-Induced
, 0.05 mg, 0.021 mg, 0.014 mg, 0.05 mg/pump actuation, 0.014 mg/pump actuation, 0.025 mg/pump actuation, 0.01275 mg
, Oral; Respiratory (inhalation), Powder, metered, Powder, metered - Oral; Respiratory (inhalation), Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Powder - Oral; Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Aerosol, Aerosol - Respiratory (inhalation)

Warnings

Wixela Inhub Contraindications
Condition
Risk Level
Notes
primary treatment of status asthmaticus
Do Not Combine
Chronic Obstructive Airway Disease
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Salmeterol may interact with Pulse Frequency
Not being treated with an inhaled corticosteroid
Do Not Combine
Asthma
Do Not Combine
There are 20 known major drug interactions with Wixela Inhub.
Common Wixela Inhub Drug Interactions
Drug Name
Risk Level
Description
(R)-warfarin
Major
The metabolism of (R)-warfarin can be decreased when combined with Salmeterol.
(S)-Warfarin
Major
The metabolism of (S)-Warfarin can be decreased when combined with Salmeterol.
Almotriptan
Major
The metabolism of Almotriptan can be decreased when combined with Salmeterol.
Aminophenazone
Major
The metabolism of Aminophenazone can be decreased when combined with Salmeterol.
Amitriptyline
Major
The metabolism of Amitriptyline can be decreased when combined with Salmeterol.
Wixela Inhub Toxicity & Overdose RiskNot much is known about the effects of fluticasone propionate in certain populations. Animal studies have shown that subcutaneous administration can cause birth defects in rats but oral administration does not have this effect. There are no known side effects when taken during pregnancy, although fluticasone propionate in human milk may affect growth and natural hormone production. Children and the elderly may be more sensitive to adverse effects. Fluticasone propionate is cleared from the body in the same way regardless of gender or race. Patients with liver problems should be monitored closely.
image of a doctor in a lab doing drug, clinical research

Wixela Inhub Novel Uses: Which Conditions Have a Clinical Trial Featuring Wixela Inhub?

There are 389 active clinical trials assessing the potential of Wixela Inhub to ameliorate Nasal Congestion, House Dust Mite Allergy and Atopic Dermatitis.
Condition
Clinical Trials
Trial Phases
Bronchospasm, Exercise-Induced
0 Actively Recruiting
Exercise-Induced Bronchospasm
1 Actively Recruiting
Phase 2
Asthma
159 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4, Early Phase 1, Phase 3
Chronic Obstructive Pulmonary Disease
100 Actively Recruiting
Phase 3, Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 4

Wixela Inhub Reviews: What are patients saying about Wixela Inhub?

5Patient Review
9/10/2022
Wixela Inhub for Controller Medication for Asthma
I had been taking Albuterol and Budesonide for a severe ASTHMA condition for over a year. I eventually had to use Albuterol 6-7 times per day to get any relief, and even then the relief amounted to only about 75%. I have now been on Wixela for almost one month and it has been very effective in completely relieving 99% of my Asthma with zero side effects.
2.7Patient Review
9/4/2022
Wixela Inhub for Controller Medication for Asthma
I was switched from Symbicort to Wixela and have been on it only a few days. Excessive coughing, lots of phlegm, Also I have lost my appetite. I have tried Trelegy successfully, am going back to it tonight.
2.3Patient Review
6/20/2022
Wixela Inhub for Controller Medication for Asthma
I experienced a lot of tightness in my chest, coughing, and shortness of breath while taking this medication. Additionally, the powder would sometimes stick to the back of my throat.
2Patient Review
6/8/2022
Wixela Inhub for Bronchospasm Prevention with COPD
Even half the recommended dosage leads to me coughing for most of the day. If I take a full dose, I can't sleep at night. The wheezing is incredibly loud and annoying. This medication really makes it hard to interact socially.
1.7Patient Review
6/6/2022
Wixela Inhub for Controller Medication for Asthma
My breathing has gotten worse since switching from Advair to Wixela
1.7Patient Review
8/21/2022
Wixela Inhub for Bronchospasm Prevention with COPD
VA switched me from symbicort to Wixela inhub. Since then my breathing is more difficult, not as effective. Wheezing and coughing more. I have since developed pneumonia. This was a cost cutting decision at the expense of our veterans' health, without question.
1.7Patient Review
9/19/2022
Wixela Inhub for Controller Medication for Asthma
I was on Advair for years with no issues, then my prescription changed to Wixela. I noticed a difference after only two days and by the fourth day, I could hardly breathe. I went back to Advair and felt better within 48 hours. There's no comparison between the two medications—Wixela is far inferior to Advair.
1.3Patient Review
6/16/2022
Wixela Inhub for Prevention of Bronchospasm with Chronic Bronchitis
Once I get below 20 puffs, it seems like the medication no longer works. This makes it difficult to breathe and is very frustrating. I've taken a few back to the pharmacy and they said the manufacturer would replace those 2 as a courtesy. However, I never had this issue with Advair and found it to be much more effective.
1Patient Review
3/25/2022
Wixela Inhub for Bronchospasm Prevention with COPD
I contacted my primary care provider through secure messaging on My health E Vet and told her how bad the new drug was. She got approval from the pharmacy to put me back on the symbicort.
1Patient Review
4/17/2022
Wixela Inhub for Bronchospasm Prevention with COPD
This drug caused my heart rate and blood pressure to spike dangerously. Inhaling it felt like trying to breathe in sand, and I coughed violently the whole time. After just one use, I could tell that this was a terrible medication; it's obviously only designed to save money for the VA while lineing the pockets of the company that produces it. Disgusting!
1Patient Review
10/3/2022
Wixela Inhub for Controller Medication for Asthma
Unfortunately, this medication caused me some problems. I ended up with a fat lip and gum irritation.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about wixela inhub

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Wixela considered a steroid?

"Wixela Inhub is a combination of a corticosteroid and a long-acting beta-adrenergic agonist (LABA) indicated for twice-daily treatment of asthma in patients aged 4 years and older or maintenance treatment of airflow obstruction and reducing exacerbations."

Answered by AI

What are the side effects of Wixela Inhub?

"The most common side effects of Wixela Inhub when used to treat asthma include upper respiratory tract infection, throat irritation, hoarseness and voice changes, thrush in your mouth or throat, bronchitis, cough, headache, and nausea and vomiting. In children with asthma, infections in the ear, nose, and throat are especially common."

Answered by AI

Is Wixela same as Advair?

"Wixela Inhub is the first FDA approved generic version of Advair Diskus. It has the same active ingredients as Advair Diskus, which have been shown in clinical studies to improve lung function throughout the day for patients with asthma or COPD."

Answered by AI

What is Wixela prescribed for?

"The product is used to control symptoms caused by asthma or ongoing lung disease. It contains two medications: fluticasone and salmeterol."

Answered by AI

Clinical Trials for Wixela Inhub

Have you considered Wixela Inhub clinical trials? We made a collection of clinical trials featuring Wixela Inhub, we think they might fit your search criteria.
Have you considered Wixela Inhub clinical trials? We made a collection of clinical trials featuring Wixela Inhub, we think they might fit your search criteria.
Have you considered Wixela Inhub clinical trials? We made a collection of clinical trials featuring Wixela Inhub, we think they might fit your search criteria.
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