Internet-Based Intervention for Head Neoplasms

Phase-Based Estimates
1
Effectiveness
2
Safety
Texas Health Care-Otolaryngology and Plastic Surgery Associates, Fort Worth, TX
Head Neoplasms+1 More
Internet-Based Intervention - Other
Eligibility
18+
All Sexes
Eligible conditions
Head Neoplasms

Study Summary

This study is evaluating whether a web-based program may help patients with head and neck cancer recover from radiation therapy.

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Eligible Conditions

  • Head Neoplasms
  • Head and Neck Neoplasms
  • Throat Carcinoma

Treatment Effectiveness

Study Objectives

This trial is evaluating whether Internet-Based Intervention will improve 1 primary outcome and 1 secondary outcome in patients with Head Neoplasms. Measurement will happen over the course of Baseline up to 6 months post-radiation.

Month 6
Changes in self-reported swallowing function
Month 6
Website usage data

Trial Safety

Safety Estimate

2 of 3
This is better than 68% of similar trials

Trial Design

2 Treatment Groups

Control
Supportive Care (Project Prepare website)

This trial requires 300 total participants across 2 different treatment groups

This trial involves 2 different treatments. Internet-Based Intervention is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase 2 and have already been tested with other people.

Supportive Care (Project Prepare website)Patients use the password-protected Project Prepare website on a computer, tablet, or phone over 10 weeks to view: videos of the swallowing and trismus exercises, tips and stories from former patients, what to expect each week of treatment, recipes and cooking demonstrations, how to take care of their teeth during treatment, strategies for stress relief, and strategies for dry mouth and nausea. This website is designed to reach underserved populations who do not have ready access to specialized preventive care.
ControlNo treatment in the control group

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: up to 6 months post-radiation
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly up to 6 months post-radiation for reporting.

Closest Location

Texas Health Care-Otolaryngology and Plastic Surgery Associates - Fort Worth, TX

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 2 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Can read and speak English or Spanish well enough to answer our questionnaires and understand our website content
Receiving radiation treatment with curative intent for throat cancer

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the signs of head neoplasms?

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The most common sign of head tumors is a headache. Other common neurological signs include hearing disturbances (hearing loss), facial palsy, balance disturbances, and tinnitus. All of these symptoms are indicative of tumors localized outside the pituitary gland. If tinnitus is the only symptom, the tumor is unlikely to be inside the pituitary gland. Tumors in the meninges can manifest as meningism. However, their diagnosis and treatment can be complicated by the fact that lesions of these structures may be asymptomatic on a radiographic screening.

Unverified Answer

What causes head neoplasms?

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Head neoplasms are commonly grouped together by the most likely origin (in the same site as the neoplasm). Head neoplasms are usually of endocrine or connective tissue origin. They have been associated with many different tumor mechanisms. They may present as a neoplasm or as a benign growth.

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How many people get head neoplasms a year in the United States?

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Around 12,813 new diagnoses of brain cancer will be made in 2022. Among patients over 65 years of age, the most common primary malignancies are brain cancers, including gliomas and meningioma.\n

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What is head neoplasms?

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Given the lack of a standard definition of how head neoplasms are graded, it is difficult to determine the exact number of head neoplasms in this article. The reported head neoplastic incidence rates of 3.4/100,000, which is high compared to most European countries, are in the range of rates recommended by the National Comprehensive Cancer Network. On the basis of the calculated yearly number of new cases, it may be calculated that the average rate for all head cancers in the Netherlands will increase from 0.5 to 6 cases/100,000 per year. From the population based data it may be estimated that about 500,000 cases of primary head and neck cancer will occur in the Netherlands within the next 25 years.

Unverified Answer

Can head neoplasms be cured?

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There should be no doubt that a malignant brain tumor cannot be cured. This is particularly the case with tumors that are highly malignant. However, this study showed that it is possible to cure tumors of one, two, or even three other organs (brain, lung, and bladder). The prognosis and the life quality of the patient are more adversely affected if the brain cancer also includes the other organs.

Unverified Answer

What are common treatments for head neoplasms?

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There is not a single treatment that can correct brain tumours; the most important treatment is symptomatic treatment and addressing the associated comorbidities. There is a paucity of randomized controlled trials and evidence from this survey suggests that some treatments with anecdotal evidence may be effective or can improve the tolerability of a patient. Patients should be monitored for improvement once the neoplasm is treated in order to identify the most appropriate neurooncologist to manage their tumors. In patients that are symptomatic, they need to be monitored for any worsening symptoms.

Unverified Answer

How serious can head neoplasms be?

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Head neoplasms in some respects present as much of a danger to the well-being of the patient as they do to the physician and patient as a whole. More work is needed to determine appropriate, reliable, and effective diagnostic techniques.

Unverified Answer

How quickly does head neoplasms spread?

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Tumours of the trigeminal ganglion are fast-growing, often aggressive and cause severe disability. We recommend MRI to determine the precise pattern of tumor's spread before deciding on a treatment response.

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Is internet-based intervention safe for people?

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Data from a recent study supports the findings of a previous study indicating that there are no measurable long-term risks associated with a Internet-based intervention.

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Have there been other clinical trials involving internet-based intervention?

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There has been no research showing whether an additional internet-based intervention over a conventional cancer information strategy has significant impact on patient outcomes compared with usual care. However, the evidence from this study suggests that the use of internet-based resources in conjunction with conventional information strategies may be effective in encouraging the use of information available both publicly and privately. This is an important finding because of the growing trend towards the publicization of health information via the internet using a combination of approaches such as (i) passive communication through web pages, email and text messaging, (ii) automated contact letters, (iii) electronic media news stories, advertisements and advertisements with a voiceover which may not necessarily have the patient's consent.

Unverified Answer

Does head neoplasms run in families?

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It appeared necessary to perform multistage analysis by applying the methodology of multiple-contrast log-likelihood test for linkage. This facilitated the localization of the gene locus to chromosome 12, where the first four nonsynonymous mutations for the development of the familial predisposition to head neoplasms were identified. The presence, in the first kindred, of the same nonsynonymous mutations in members of 3 independent families with familial encephalopathy and an autosomal recessiveness in the same area of a chromosome suggests the existence of a gene or genes underlying familial head neoplasms predisposition which may be a candidate gene for encephalopathy.

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What are the chances of developing head neoplasms?

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Based on the age of presentation, the probability of neuroectodermal tumor is more than twice as high as that of other head and neck tumors. Other risk factors that may contribute are smoking, exposure to ionizing radiation, familial cancer syndromes (e.g. Li-Fraumeni syndrome) and head and neck radiation prophylaxis.

Unverified Answer
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