Tobi Podhaler

Bacteria, Cystic Fibrosis, Septicemia + 19 more
Treatment
9 Active Studies for Tobi Podhaler

What is Tobi Podhaler

TobramycinThe Generic name of this drug
Treatment SummaryTobramycin is an antibiotic derived from the soil bacterium _Streptomyces spp._ It is effective against a wide range of bacteria, including both Gram-positive and Gram-negative organisms. Tobramycin is commonly used to treat chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as this bacteria is resistant to many other antibiotics. It can also be administered intravenously and applied to the skin or eyes to treat various bacterial infections. However, it can cause kidney and hearing damage, which limits its use in some cases. Tobramycin was approved by the FDA in 1975 and
Tobrexis the brand name
Tobi Podhaler Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Tobrex
Tobramycin
1981
166

Effectiveness

How Tobi Podhaler Affects PatientsTobramycin is a type of antibiotic that is effective against many bacteria, including dangerous biothreat agents like Yersinia pestis and Francisella tularensis. It is also active against some Gram-positive bacteria. However, taking tobramycin carries the risk of damaging the kidneys, ears, and muscles. It can also cross the placenta, possibly causing deafness in babies born to mothers who took tobramycin while pregnant. All forms of tobramycin can also cause allergic reactions ranging from mild to life-threatening.
How Tobi Podhaler works in the bodyTobramycin is an antibiotic that works against a variety of bacteria. It does this by binding to bacterial membranes, increasing the permeability of the cell walls, and entering the cell. Once inside, the antibiotic blocks the bacterial ribosome, which is responsible for producing proteins. This stops the bacteria from producing the proteins they need to survive, eventually leading to their death. Bacteria can become resistant to tobramycin by making changes to the ribosome or by blocking the transport of tobramycin across their cell walls.

When to interrupt dosage

The suggested dosage of Tobi Podhaler is contingent upon the determined condition, such as Cystic Fibrosis (CF), steroid-responsive inflammation and Meningitis, Bacterial. The amount of dosage is reliant upon the delivery technique delineated in the table below.
Condition
Dosage
Administration
Bacteria
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Cystic Fibrosis
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
ocular bacterial infections
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Bacterial Infections
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Eye Infections
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Urinary tract infection
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
External auditory canal structure
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Intraabdominal Infections
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Meningitis, Bacterial
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Burkholderia Cepacia Infection
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Bacterial Peritonitis
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Eye Infections, Bacterial
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Adrenal Cortex Hormones
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
FEV1 <25% predicted
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
FEV1 >80% predicted
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Bone Infection
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Ocular Inflammation
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Septicemia
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Cystic Fibrosis (CF)
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
concomitant use of NSAID
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)

Warnings

Tobi Podhaler Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Tobi Podhaler.
Common Tobi Podhaler Drug Interactions
Drug Name
Risk Level
Description
Neomycin
Major
The risk or severity of nephrotoxicity can be increased when Tobramycin is combined with Neomycin.
Tenofovir
Major
Tobramycin may increase the nephrotoxic activities of Tenofovir.
Tenofovir alafenamide
Major
Tobramycin may increase the nephrotoxic activities of Tenofovir alafenamide.
Tenofovir disoproxil
Major
Tobramycin may increase the nephrotoxic activities of Tenofovir disoproxil.
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Tobramycin.
Tobi Podhaler Toxicity & Overdose RiskThere is limited information available about the toxicity of tobramycin. People who have taken an overdose of tobramycin may experience serious side effects such as kidney damage, hearing loss, disruption in muscle movement, and difficulty breathing. Treatment is usually supportive, and dialysis may help remove the drug from the body. It is very unlikely to overdose on tobramycin accidentally, as it is not well absorbed in the digestive system. Animal studies have shown that the lethal dose of tobramycin is very high when given by mouth, and much lower when given through an injection.
image of a doctor in a lab doing drug, clinical research

Tobi Podhaler Novel Uses: Which Conditions Have a Clinical Trial Featuring Tobi Podhaler?

8 clinical trials are currently underway to investigate the potential of Tobi Podhaler in alleviating symptoms of Cystic Fibrosis, ocular bacterial infections and Bacterial Infections.
Condition
Clinical Trials
Trial Phases
Cystic Fibrosis
0 Actively Recruiting
Septicemia
0 Actively Recruiting
ear infection-not otherwise specified caused by susceptible bacteria
0 Actively Recruiting
Eye Infections, Bacterial
0 Actively Recruiting
Bacteria
0 Actively Recruiting
Bacterial Infections
1 Actively Recruiting
Phase 4
Urinary tract infection
0 Actively Recruiting
External auditory canal structure
0 Actively Recruiting
concomitant use of NSAID
0 Actively Recruiting
Bacterial Peritonitis
0 Actively Recruiting
FEV1 >80% predicted
0 Actively Recruiting
FEV1 <25% predicted
0 Actively Recruiting
Eye Infections
1 Actively Recruiting
Phase 4
Intraabdominal Infections
3 Actively Recruiting
Not Applicable, Phase 4
steroid-responsive inflammation
0 Actively Recruiting
ocular bacterial infections
0 Actively Recruiting
Cystic Fibrosis (CF)
0 Actively Recruiting
Burkholderia Cepacia Infection
0 Actively Recruiting
Bone Infection
1 Actively Recruiting
Phase 2
Adrenal Cortex Hormones
0 Actively Recruiting

Patient Q&A Section about tobi podhaler

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is TOBI Podhaler used for?

"This can cause difficulty breathing,Wheezing and other symptoms.

This medication is used to treat people with cystic fibrosis who have persistent lung infection with a certain bacteria (Pseudomonas aeruginosa). Cystic fibrosis patients produce thick, sticky mucus that can plug up the tubes, ducts and passageways in lungs, causing difficulty breathing, wheezing and other symptoms."

Answered by AI

What is tobramycin Tobi used for?

"Tobi is a prescription medication used to treat the symptoms of lung infections in patients with Cystic fibrosis. Tobi may be used alone or with other medications. Tobi belongs to a class of drugs called aminoglycosides."

Answered by AI

How much does TOBI Podhaler cost?

"The price for TOBI Podhaler inhalation capsule 28 mg is about $10,683 for a supply of 224, depending on the pharmacy you go to."

Answered by AI

Who makes TOBI Podhaler?

"If you have any suspected side effects from taking Podhaler, please contact Novartis Pharmaceuticals Corporation at 1-888-669-6682 or the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch."

Answered by AI

Clinical Trials for Tobi Podhaler

Have you considered Tobi Podhaler clinical trials? We made a collection of clinical trials featuring Tobi Podhaler, we think they might fit your search criteria.