Tobi Podhaler

Q: What is TOBI Podhaler used for?

This can cause difficulty breathing,Wheezing and other symptoms. This medication is used to treat people with <a href="https://www.withpower.com/clinical-trials/cystic-fibrosis">cystic fibrosis</a> who have persistent lung infection with a certain bacteria (Pseudomonas aeruginosa). Cystic fibrosis patients produce thick, sticky mucus that can plug up the tubes, ducts and passageways in lungs, causing difficulty breathing, wheezing and other symptoms.

Q: What is tobramycin Tobi used for?

Tobi is a prescription medication used to treat the symptoms of lung infections in patients with <a href="https://www.withpower.com/clinical-trials/cystic-fibrosis">Cystic fibrosis</a>. Tobi may be used alone or with other medications. Tobi belongs to a class of drugs called aminoglycosides.

Q: How much does TOBI Podhaler cost?

The price for TOBI Podhaler inhalation capsule 28 mg is about $10,683 for a supply of 224, depending on the pharmacy you go to.

Q: Who makes TOBI Podhaler?

If you have any suspected side effects from taking Podhaler, please contact Novartis Pharmaceuticals Corporation at 1-888-669-6682 or the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Bacteria, Cystic Fibrosis, Septicemia + 19 more

Treatment

1 Active Study for Tobi Podhaler

Treatment for

Bacteria

What is Tobi Podhaler

Tobramycin

The Generic name of this drug

Treatment Summary

Tobramycin is an antibiotic derived from the soil bacterium _Streptomyces spp._ It is effective against a wide range of bacteria, including both Gram-positive and Gram-negative organisms. Tobramycin is commonly used to treat chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as this bacteria is resistant to many other antibiotics. It can also be administered intravenously and applied to the skin or eyes to treat various bacterial infections. However, it can cause kidney and hearing damage, which limits its use in some cases. Tobramycin was approved by the FDA in 1975 and

Tobrex

is the brand name

Tobi Podhaler Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Tobrex

Tobramycin

1981

166

Effectiveness

How Tobi Podhaler Affects Patients

Tobramycin is a type of antibiotic that is effective against many bacteria, including dangerous biothreat agents like Yersinia pestis and Francisella tularensis. It is also active against some Gram-positive bacteria. However, taking tobramycin carries the risk of damaging the kidneys, ears, and muscles. It can also cross the placenta, possibly causing deafness in babies born to mothers who took tobramycin while pregnant. All forms of tobramycin can also cause allergic reactions ranging from mild to life-threatening.

How Tobi Podhaler works in the body

Tobramycin is an antibiotic that works against a variety of bacteria. It does this by binding to bacterial membranes, increasing the permeability of the cell walls, and entering the cell. Once inside, the antibiotic blocks the bacterial ribosome, which is responsible for producing proteins. This stops the bacteria from producing the proteins they need to survive, eventually leading to their death. Bacteria can become resistant to tobramycin by making changes to the ribosome or by blocking the transport of tobramycin across their cell walls.

When to interrupt dosage

The suggested dosage of Tobi Podhaler is contingent upon the determined condition, such as Cystic Fibrosis (CF), steroid-responsive inflammation and Meningitis, Bacterial. The amount of dosage is reliant upon the delivery technique delineated in the table below.

Condition

Dosage

Administration

Conjunctivitis