Serophene

Ovulatory Dysfunction
Treatment
1 FDA approval
1 Active Study for Serophene

What is Serophene

ClomifeneThe Generic name of this drug
Treatment SummaryA triphenyl ethylene stilbene derivative is a drug that acts as either an estrogen stimulator or suppressor, depending on the body tissue it is targeting.
Clomidis the brand name
image of different drug pills on a surface
Serophene Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Clomid
Clomifene
1967
19

Approved as Treatment by the FDA

Clomifene, otherwise called Clomid, is approved by the FDA for 1 uses which include Ovulatory Dysfunction .
Ovulatory Dysfunction

Effectiveness

How Serophene Affects PatientsClomifene is a drug taken by mouth to help cause ovulation. It can increase the chance of having twins, as well as causing weight gain and having a possible link to ovarian cancer. When taken, it works by causing hormones in the body to be released, leading to an increase in estrogen, which then causes an egg to be released. After ovulation, the levels of estrogen and progesterone will rise and fall like in a normal cycle.
How Serophene works in the bodyClomifene helps to trigger the release of hormones that lead to the development of an egg and its release from the ovary. It also works to reduce the influence of estrogen in the brain and uterus, which can lead to increased production of stimulatory hormones. Clomifene does not appear to interact with other hormones in the body and is not known to have any progestational, androgenic, or antiandrogenic effects.

When to interrupt dosage

The measure of Serophene is founded on the identified condition. The magnitude of dosage is contingent upon the technique of delivery (e.g. Tablet - Oral or Oral) enumerated in the table underneath.
Condition
Dosage
Administration
Ovulatory Dysfunction
, 50.0 mg
, Oral, Tablet, Tablet - Oral

Warnings

There are 20 known major drug interactions with Serophene.
Common Serophene Drug Interactions
Drug Name
Risk Level
Description
Ospemifene
Major
The risk or severity of adverse effects can be increased when Clomifene is combined with Ospemifene.
Abemaciclib
Moderate
The serum concentration of Abemaciclib can be increased when it is combined with Clomifene.
Ambrisentan
Moderate
The serum concentration of Ambrisentan can be increased when it is combined with Clomifene.
Apixaban
Moderate
The serum concentration of Apixaban can be increased when it is combined with Clomifene.
Avanafil
Moderate
The serum concentration of Avanafil can be increased when it is combined with Clomifene.
Serophene Toxicity & Overdose RiskThe amount of clomifene needed to cause toxicity in mice is 1700mg/kg, and in rats is 5750mg/kg. It is not known what the toxic dose in humans is. No reports of toxic effects due to an overdose on clomifene have been reported, but those who take an excessive amount may experience nausea, vomiting, hot flashes, blurred vision, spots or flashes, vision spots, and abdominal or pelvic pain from enlarged ovaries.
image of a doctor in a lab doing drug, clinical research

Serophene Novel Uses: Which Conditions Have a Clinical Trial Featuring Serophene?

A single study is currently in progress to determine the efficacy of Serophene in addressing Ovulatory Dysfunction.
Condition
Clinical Trials
Trial Phases
Ovulatory Dysfunction
1 Actively Recruiting
Early Phase 1

Serophene Reviews: What are patients saying about Serophene?

3Patient Review
12/30/2013
Serophene for Osteoporosis
This drug is effective. I'm grateful for modern medicine.
3Patient Review
6/26/2013
Serophene for Osteoporosis
This drug is great. It really helped me.
3Patient Review
12/30/2013
Serophene for Osteoporosis
This drug is great. It really helped me.
3Patient Review
9/30/2014
Serophene for Female Problems Causing Trouble in Getting Pregnant
This drug is great. I'm grateful for modern medicine.
2.3Patient Review
1/10/2008
Serophene for Female Problems Causing Trouble in Getting Pregnant
We're now on our sixth month of Serphene with no success. I did have a lot of pain during ovulation for the first three months, but it doesn't seem to be effective anymore.
2.3Patient Review
1/28/2017
Serophene for Low Sperm Count
Serophene has not been effective for me in terms of increasing my sperm count.
2Patient Review
10/20/2016
Serophene for Low Sperm Count
I've been taking this medication for two months now, and I've noticed my breasts have become very tender. I also experience a lot of cramping and discharge.
1.3Patient Review
11/12/2008
Serophene for Female Problems Causing Trouble in Getting Pregnant
I saw a significant and unfortunate increase in weight after only two weeks of taking this medication.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about serophene

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Serophene and Clomid the same thing?

"The text is discussing the different names for the drug Clomid, which is also known as clomiphene citrate or Serophene. All three of these drugs are thought to have the same effect."

Answered by AI

What is Serophene used for?

"This medication is used to help women who are having trouble conceiving. It works by increasing the levels of hormones that support the development and release of a mature egg. However, this medication is not recommended for women who have primary pituitary or ovarian failure, as their ovaries no longer produce eggs properly."

Answered by AI

What is the side effect of clomiphene citrate?

"If you experience any of the following side effects, tell your doctor or pharmacist: stomach upset, bloating, abdominal/pelvic fullness, flushing ("hot flashes"), breast tenderness, headache, or dizziness."

Answered by AI

Clinical Trials for Serophene