Qudexy Xr

Tonic - clonic seizures, BMI >27 kg/m2, Epilepsy + 15 more

Treatment

20 Active Studies for Qudexy Xr

Treatment for

Tonic - clonic seizures

What is Qudexy Xr

TopiramateThe Generic name of this drug

Treatment SummaryTopiramate is a medication used to control epilepsy and prevent migraine headaches. It was first approved by the FDA in 1996 and later approved for migraine prevention in adults in 2004. It is also used in combination with another drug, phentermine, to help adults lose weight. It has an unusual chemical structure composed of sulfamate and oxygen, which was discovered by chance during the development of an antidiabetic medication.

Topamaxis the brand name

Qudexy Xr Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Topamax

Topiramate

1997

524

Effectiveness

How Qudexy Xr Affects PatientsTopiramate helps to prevent seizures and migraine symptoms by decreasing the activity of neurons in the brain. However, it can also cause metabolic acidosis, changes in mood, suicidal thoughts or attempts, and kidney stones. Taking topiramate with another drug called valproic acid can also lead to hypothermia.

How Qudexy Xr works in the bodySeizures are caused by an electrical disruption in the brain, which causes a temporary disruption of normal brain activity. Topiramate is used to treat these seizures and migraines, although the exact way it works is not fully understood. It likely works by blocking sodium channels in the brain and increasing activity of inhibitory GABA-A receptors while reducing activity of stimulating glutamate receptors. This decreases the electrical signals in the brain, preventing seizures and migraines. Topiramate also blocks some carbonic anhydrase isozymes, but it is unclear what impact this has.

When to interrupt dosage

The recommended dosage of Qudexy Xr is contingent upon the diagnosed condition, including Seizures, Weight Reduction and Tonic - clonic seizures. The quantity of dosage fluctuates as per the procedure of delivery (e.g. Tablet, coated or Tablet) specified in the table underneath.

Condition

Dosage

Administration

Seizures

200.0 mg, 50.0 mg, 100.0 mg, 25.0 mg, , 150.0 mg, 15.0 mg, 69.0 mg, 92.0 mg, 46.0 mg, 23.0 mg, 25.0 meq, 25.0 mg/mL

Tablet, coated, Tablet, Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets - Oral, Tablet - Oral, Capsule, Tablet, coated - Oral, , Tablet, film coated - Oral, Capsule, coated pellets, Tablet, film coated, Solution - Oral, Capsule - Oral, Solution

Weight Reduction

200.0 mg, 50.0 mg, 100.0 mg, 25.0 mg, , 150.0 mg, 15.0 mg, 69.0 mg, 92.0 mg, 46.0 mg, 23.0 mg, 25.0 meq, 25.0 mg/mL

Tablet, coated, Tablet, Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets - Oral, Tablet - Oral, Capsule, Tablet, coated - Oral, , Tablet, film coated - Oral, Capsule, coated pellets, Tablet, film coated, Solution - Oral, Capsule - Oral, Solution

Tonic - clonic seizures

200.0 mg, 50.0 mg, 100.0 mg, 25.0 mg, , 150.0 mg, 15.0 mg, 69.0 mg, 92.0 mg, 46.0 mg, 23.0 mg, 25.0 meq, 25.0 mg/mL

Tablet, coated, Tablet, Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets - Oral, Tablet - Oral, Capsule, Tablet, coated - Oral, , Tablet, film coated - Oral, Capsule, coated pellets, Tablet, film coated, Solution - Oral, Capsule - Oral, Solution

BMI >27 kg/m2

200.0 mg, 50.0 mg, 100.0 mg, 25.0 mg, , 150.0 mg, 15.0 mg, 69.0 mg, 92.0 mg, 46.0 mg, 23.0 mg, 25.0 meq, 25.0 mg/mL

Tablet, coated, Tablet, Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets - Oral, Tablet - Oral, Capsule, Tablet, coated - Oral, , Tablet, film coated - Oral, Capsule, coated pellets, Tablet, film coated, Solution - Oral, Capsule - Oral, Solution

Epilepsy

200.0 mg, 50.0 mg, 100.0 mg, 25.0 mg, , 150.0 mg, 15.0 mg, 69.0 mg, 92.0 mg, 46.0 mg, 23.0 mg, 25.0 meq, 25.0 mg/mL

Tablet, coated, Tablet, Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets - Oral, Tablet - Oral, Capsule, Tablet, coated - Oral, , Tablet, film coated - Oral, Capsule, coated pellets, Tablet, film coated, Solution - Oral, Capsule - Oral, Solution

Mood Disorders

200.0 mg, 50.0 mg, 100.0 mg, 25.0 mg, , 150.0 mg, 15.0 mg, 69.0 mg, 92.0 mg, 46.0 mg, 23.0 mg, 25.0 meq, 25.0 mg/mL

Tablet, coated, Tablet, Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets - Oral, Tablet - Oral, Capsule, Tablet, coated - Oral, , Tablet, film coated - Oral, Capsule, coated pellets, Tablet, film coated, Solution - Oral, Capsule - Oral, Solution

at least one weight-related comorbid condition

200.0 mg, 50.0 mg, 100.0 mg, 25.0 mg, , 150.0 mg, 15.0 mg, 69.0 mg, 92.0 mg, 46.0 mg, 23.0 mg, 25.0 meq, 25.0 mg/mL

Tablet, coated, Tablet, Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets - Oral, Tablet - Oral, Capsule, Tablet, coated - Oral, , Tablet, film coated - Oral, Capsule, coated pellets, Tablet, film coated, Solution - Oral, Capsule - Oral, Solution

Alcoholism

200.0 mg, 50.0 mg, 100.0 mg, 25.0 mg, , 150.0 mg, 15.0 mg, 69.0 mg, 92.0 mg, 46.0 mg, 23.0 mg, 25.0 meq, 25.0 mg/mL

Tablet, coated, Tablet, Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets - Oral, Tablet - Oral, Capsule, Tablet, coated - Oral, , Tablet, film coated - Oral, Capsule, coated pellets, Tablet, film coated, Solution - Oral, Capsule - Oral, Solution

Lennox Gastaut Syndrome (LGS)

200.0 mg, 50.0 mg, 100.0 mg, 25.0 mg, , 150.0 mg, 15.0 mg, 69.0 mg, 92.0 mg, 46.0 mg, 23.0 mg, 25.0 meq, 25.0 mg/mL

Tablet, coated, Tablet, Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets - Oral, Tablet - Oral, Capsule, Tablet, coated - Oral, , Tablet, film coated - Oral, Capsule, coated pellets, Tablet, film coated, Solution - Oral, Capsule - Oral, Solution

Obesity

200.0 mg, 50.0 mg, 100.0 mg, 25.0 mg, , 150.0 mg, 15.0 mg, 69.0 mg, 92.0 mg, 46.0 mg, 23.0 mg, 25.0 meq, 25.0 mg/mL

Tablet, coated, Tablet, Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets - Oral, Tablet - Oral, Capsule, Tablet, coated - Oral, , Tablet, film coated - Oral, Capsule, coated pellets, Tablet, film coated, Solution - Oral, Capsule - Oral, Solution

prophylaxis of migraine headaches

200.0 mg, 50.0 mg, 100.0 mg, 25.0 mg, , 150.0 mg, 15.0 mg, 69.0 mg, 92.0 mg, 46.0 mg, 23.0 mg, 25.0 meq, 25.0 mg/mL

Tablet, coated, Tablet, Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets - Oral, Tablet - Oral, Capsule, Tablet, coated - Oral, , Tablet, film coated - Oral, Capsule, coated pellets, Tablet, film coated, Solution - Oral, Capsule - Oral, Solution

High cholesterol

200.0 mg, 50.0 mg, 100.0 mg, 25.0 mg, , 150.0 mg, 15.0 mg, 69.0 mg, 92.0 mg, 46.0 mg, 23.0 mg, 25.0 meq, 25.0 mg/mL

Tablet, coated, Tablet, Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets - Oral, Tablet - Oral, Capsule, Tablet, coated - Oral, , Tablet, film coated - Oral, Capsule, coated pellets, Tablet, film coated, Solution - Oral, Capsule - Oral, Solution

Hypertensive disease

200.0 mg, 50.0 mg, 100.0 mg, 25.0 mg, , 150.0 mg, 15.0 mg, 69.0 mg, 92.0 mg, 46.0 mg, 23.0 mg, 25.0 meq, 25.0 mg/mL

Tablet, coated, Tablet, Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets - Oral, Tablet - Oral, Capsule, Tablet, coated - Oral, , Tablet, film coated - Oral, Capsule, coated pellets, Tablet, film coated, Solution - Oral, Capsule - Oral, Solution

Weight

200.0 mg, 50.0 mg, 100.0 mg, 25.0 mg, , 150.0 mg, 15.0 mg, 69.0 mg, 92.0 mg, 46.0 mg, 23.0 mg, 25.0 meq, 25.0 mg/mL

Tablet, coated, Tablet, Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets - Oral, Tablet - Oral, Capsule, Tablet, coated - Oral, , Tablet, film coated - Oral, Capsule, coated pellets, Tablet, film coated, Solution - Oral, Capsule - Oral, Solution

Type 2 Diabetes

200.0 mg, 50.0 mg, 100.0 mg, 25.0 mg, , 150.0 mg, 15.0 mg, 69.0 mg, 92.0 mg, 46.0 mg, 23.0 mg, 25.0 meq, 25.0 mg/mL

Tablet, coated, Tablet, Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets - Oral, Tablet - Oral, Capsule, Tablet, coated - Oral, , Tablet, film coated - Oral, Capsule, coated pellets, Tablet, film coated, Solution - Oral, Capsule - Oral, Solution

Calorie Restriction

200.0 mg, 50.0 mg, 100.0 mg, 25.0 mg, , 150.0 mg, 15.0 mg, 69.0 mg, 92.0 mg, 46.0 mg, 23.0 mg, 25.0 meq, 25.0 mg/mL

Tablet, coated, Tablet, Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets - Oral, Tablet - Oral, Capsule, Tablet, coated - Oral, , Tablet, film coated - Oral, Capsule, coated pellets, Tablet, film coated, Solution - Oral, Capsule - Oral, Solution

Migraine

200.0 mg, 50.0 mg, 100.0 mg, 25.0 mg, , 150.0 mg, 15.0 mg, 69.0 mg, 92.0 mg, 46.0 mg, 23.0 mg, 25.0 meq, 25.0 mg/mL

Tablet, coated, Tablet, Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets - Oral, Tablet - Oral, Capsule, Tablet, coated - Oral, , Tablet, film coated - Oral, Capsule, coated pellets, Tablet, film coated, Solution - Oral, Capsule - Oral, Solution

Exercise

200.0 mg, 50.0 mg, 100.0 mg, 25.0 mg, , 150.0 mg, 15.0 mg, 69.0 mg, 92.0 mg, 46.0 mg, 23.0 mg, 25.0 meq, 25.0 mg/mL

Tablet, coated, Tablet, Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets - Oral, Tablet - Oral, Capsule, Tablet, coated - Oral, , Tablet, film coated - Oral, Capsule, coated pellets, Tablet, film coated, Solution - Oral, Capsule - Oral, Solution

Warnings

Qudexy Xr Contraindications

Condition

Risk Level

Notes

Metabolic Acidosis

Do Not Combine

There are 20 known major drug interactions with Qudexy Xr.

Common Qudexy Xr Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Topiramate.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be increased when combined with Topiramate.

Acenocoumarol

Major

The metabolism of Acenocoumarol can be increased when combined with Topiramate.

Alectinib

Major

The metabolism of Alectinib can be increased when combined with Topiramate.

Alpelisib

Major

The metabolism of Alpelisib can be increased when combined with Topiramate.

Qudexy Xr Toxicity & Overdose RiskThe toxic dose of topiramate in rats is above 1500 mg/kg. People who overdose on topiramate may experience symptoms such as low blood pressure, extreme acidity in the body, coma, stomach pain, vision problems, seizures, drowsiness, trouble speaking, confusion, dizziness, agitation, and depression. If the overdose is recent, doctors may suggest vomiting or pumping the stomach, as well as providing supportive care with activated charcoal and hemodialysis.

Qudexy Xr Novel Uses: Which Conditions Have a Clinical Trial Featuring Qudexy Xr?

313 active clinical trials are currently being conducted to assess the potential of Qudexy Xr to ameliorate Type 2 Diabetes, Migraine and Exercise-related issues.

Condition

Clinical Trials

Trial Phases

Exercise

57 Actively Recruiting

Phase 1, Not Applicable, Early Phase 1, Phase 3

Type 2 Diabetes

173 Actively Recruiting

Phase 2, Not Applicable, Phase 4, Early Phase 1, Phase 1, Phase 3

Weight

0 Actively Recruiting

Migraine

61 Actively Recruiting

Not Applicable, Phase 1, Phase 4, Phase 2, Phase 3

Mood Disorders

1 Actively Recruiting

Not Applicable

Hypertensive disease

18 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4

Alcoholism

8 Actively Recruiting

Phase 3, Not Applicable, Phase 2

Weight Reduction

0 Actively Recruiting

High cholesterol

4 Actively Recruiting

Phase 2, Not Applicable, Phase 3, Phase 1

at least one weight-related comorbid condition

0 Actively Recruiting

Obesity

0 Actively Recruiting

BMI >27 kg/m2

0 Actively Recruiting

Calorie Restriction

0 Actively Recruiting

Seizures

3 Actively Recruiting

Phase 2, Phase 3

Lennox Gastaut Syndrome (LGS)

4 Actively Recruiting

Phase 2, Phase 3

prophylaxis of migraine headaches

0 Actively Recruiting

Epilepsy

0 Actively Recruiting

Tonic - clonic seizures

0 Actively Recruiting

Qudexy Xr Reviews: What are patients saying about Qudexy Xr?

5Patient Review

9/11/2017

Qudexy Xr for Migraine Prevention

I use this because I have basilar migraines and i was on 100 mg of topomax xr but it stopped working for me so my neurologist bumped me up to 150mg to quedexy and it works great for me i have had no probelms! when i was taking the topomax I had tingling in my fingers and toes and knees and I also had nightmares for a month everytime I closed my eyes, but with quedexy I have never felt better!

2.7Patient Review

10/17/2016

Qudexy Xr for Migraine Prevention

I was previously taking topamax 100mg, but my doctor switched me to Qudexy at my annual visit. I found that I wasn't in a fog anymore, which was great! However, I experienced terrible stomach issues and bad tingling in my arms and legs. I tried staying with the medication for 3 weeks, but the stomach problems were too much to handle. I'm currently trying Trokendi to see if it will be more effective.

2Patient Review

1/14/2021

Qudexy Xr for Migraine Prevention

Although this medication did help to lessen my migraines by half, the hair loss after just three months was not worth it. Additionally, I frequently felt tingling in my fingers and toes while taking this drug.

1.7Patient Review

7/15/2016

Qudexy Xr for Migraine Prevention

I experienced a lot of negative side effects, like nausea and suicidal thoughts. This medication was ineffective for me, so I do not recommend it to others who are looking for relief from migraines.

Patient Q&A Section about qudexy xr

What are the side effects of Qudexy XR?

"The following effects may occur: fatigue, drowsiness, dizziness, loss of coordination, tingling in the extremities, loss of appetite, changes in food taste, diarrhea, and weight loss." - Anonymous Online Contributor

Unverified Answer

What is Qudexy XR used for?

"Qudexy XR is a prescription medicine that can be used to prevent migraine headaches in adults and adolescents 12 years and older, and to treat certain types of seizures (partial-onset seizures and primary generalized tonic-clonic seizures) in adults and children 2 years and older." - Anonymous Online Contributor

Unverified Answer

Is Qudexy the same as topiramate?

"The active ingredient in both Topiramate Extended-Release Capsules and Qudexy® XR is topiramate. Topiramate Extended-Release Capsules are manufactured by Upsher-Smith, while Qudexy® XR is manufactured by UCB, Inc." - Anonymous Online Contributor

Unverified Answer

Is Qudexy XR used for weight loss?

"No, you should not use Qudexy XR for weight loss. Although weight loss is a potential side effect of the medication, the main purpose of Qudexy XR is to help people with epilepsy or those who suffer from migraines." - Anonymous Online Contributor

Unverified Answer

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Clinical Trials for Qudexy Xr

Image of University of Colorado Department of Family Medicine in Aurora, United States.

Phase-Based Progress Estimates

Glucose Excursion Minimization (GEM)for Type 2 Diabetes

This trial tests if self-managed diabetes treatment can be more effective and cost less than traditional meds for newly-diagnosed Type 2 Diabetes.

Waitlist Available

University of Colorado Department of Family Medicine (+1 Sites)Daniel J. Cox, PhD, AHPPDexCom, Inc.

Image of Charles R. Drew University in Los Angeles, United States.

Phase-Based Progress Estimates

Intervention Group (IG)for Type 2 Diabetes

Los Angeles, CA

This trial observes the impact of a tailored education program on colorectal cancer screening & dietary habits in minority patients w/ type 2 diabetes.

Waitlist Available

Charles R. Drew University

Image of Wake Forest University Health Sciences in Winston-Salem, United States.

Phase-Based Progress Estimates

Telehealth-based Clinical Pharmacy Interventionfor Type 2 Diabetes

Winston-Salem, NC

This trial studies if having a pharmacist help rural patients with Type 2 Diabetes in primary care will be beneficial.

Waitlist Available

Wake Forest University Health SciencesRohan Mahabaleshwarkar, PhD

Image of Clinical Trial Site in Montréal, Canada.

Phase-Based Progress Estimates

Part A: ALN-KHKfor Type 2 Diabetes

Montréal, Canada

This trial tests how safe and effective a drug is and how it works in the body when given in single or multiple doses.

Clinical Trial SiteMedical DirectorAlnylam Pharmaceuticals

Have you considered Qudexy Xr clinical trials? We made a collection of clinical trials featuring Qudexy Xr, we think they might fit your search criteria.

Explore trials for Qudexy Xr

Image of Vancouver Island Health Authority /ID# 247733 in Victoria, Canada.

Phase-Based Progress Estimates

Atogepantfor Migraine

Victoria, Canada

This trial will study whether a medicine (atogepant) is safe and effective for preventing migraine symptoms compared to another medicine (topiramate). 520 participants will be enrolled worldwide. Both medicines are taken by mouth.

Waitlist Available

Vancouver Island Health Authority /ID# 247733 (+2 Sites)ABBVIE INC.AbbVie

Image of Rachel W. Goode in Kannapolis, United States.

Phase-Based Progress Estimates

DSMES + ASE Intervention Appetite Self-Regulation (Centering Appetite)for Type 2 Diabetes

This trial will test if an app & Fitbit can help African Americans with type 2 diabetes lower glucose and binge eating. They'll receive online lessons and be monitored for 6 months.

Waitlist Available

Rachel W. GoodeRachel Goode, PhD, MPH, LCSW

Image of Washington University School of Medicine in Saint Louis, United States.

Phase-Based Progress Estimates

Migrainefor Migraine

Saint Louis, MO

This trial studies how hormones affect pain and migraine severity in both men and women.

Washington University School of MedicineHadas Nahman-Averbuch, PhD

Image of Southwest General Healthcare Center in Fort Myers, United States.

Phase-Based Progress Estimates

Phase 1 (SAD Cohorts)for Type 2 Diabetes

This trial tests safety, tolerability & effects of BMF-219, an oral drug for adults with Type 2 Diabetes Mellitus.

Southwest General Healthcare Center (+5 Sites)Stephen Morris, MDBiomea Fusion Inc.

Have you considered Qudexy Xr clinical trials? We made a collection of clinical trials featuring Qudexy Xr, we think they might fit your search criteria.

Explore trials for Qudexy Xr

Image of Kaiser Permanente in Berkeley, United States.

Phase-Based Progress Estimates

CGA-rich Coffee (Speciality Coffee)for Type 2 Diabetes

This trial explores the effects of specialty coffee on cognitive function & blood sugar control in people with diabetes, to reduce risk of cognitive decline & diabetes.

Kaiser PermanenteDaniel Lamport, PhD

Image of Montreal Heart Institute in Montréal, Canada.

Phase-Based Progress Estimates

EC ASA 81 Mg Twice Daily For 7 Daysfor Platelet Aggregation

Montréal, Canada

This trial will study if different doses of aspirin help type 2 diabetes patients. It'll compare response to one dose of 80mg, two doses of 80mg, one dose of 162mg and two doses of 40mg. Results will help decide best dose for larger future trials.

Waitlist Available

Montreal Heart InstituteGuillaume Marquis Gravel, MD, MSc

Image of Research Site in Glendale, United States.

Phase-Based Progress Estimates

Cohort 1 (healthy Volunteers)for Type 2 Diabetes

This trial tests a new drug's safety, side effects, and how it's absorbed in healthy adults.

Research SiteEsther Yoon, MDAstraZeneca

Image of Vanderbilt University in Nashville, United States.

Phase-Based Progress Estimates

Intervention Groupfor Type 2 Diabetes

This trial will test a 12-week program to help diabetes patients reduce sedentary behavior and move more. The effects on physical activity, cardiometabolic markers and patient-centered outcomes will also be studied.

Vanderbilt UniversityChorong Park, PhD

Have you considered Qudexy Xr clinical trials? We made a collection of clinical trials featuring Qudexy Xr, we think they might fit your search criteria.

Explore trials for Qudexy Xr

Unbiased ResultsWe believe in providing patients with all the options.

Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.

Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.

Back to top

Terms of Service Privacy Policy Security