What is Prograf
TacrolimusThe Generic name of this drug
Treatment SummaryTacrolimus (also known as FK-506 or Fujimycin) is a medicine used to prevent organ rejection after transplantation. It is also used to treat severe cases of atopic dermatitis, uveitis, and vitiligo. The drug was first discovered in 1984 from a soil sample in Japan. Tacrolimus is a macrolide that works by binding to a protein called FKBP-12, which then inhibits the activity of the immune system and reduces the risk of organ rejection.
Prografis the brand name
Prograf Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Prograf
Tacrolimus
1994
138
Approved as Treatment by the FDA
Tacrolimus, also called Prograf, is approved by the FDA for 3 uses such as Kidney Transplantation and Kidney .Kidney Transplantation
Kidney
Immunosuppressive Treatment
Effectiveness
How Prograf Affects PatientsTacrolimus works by blocking a certain enzyme, stopping certain signals from being sent to the T-lymphocytes, and reducing the amount of a certain protein. Compared to cyclosporine, tacrolimus is more effective in reducing organ rejection. It can also be used to treat eczema, though it is not as strong as steroids. An advantage of tacrolimus is that it can be used on the face, while steroids cannot. For other parts of the body, steroids are usually the better treatment.
How Prograf works in the bodyWe don't know exactly how tacrolimus works to treat atopic dermatitis, but we have seen a few things. It appears to limit T-lymphocyte activation by binding to a protein called FKBP-12. This stops a process called dephosphorylation from happening, which is necessary for the formation of lymphokines. Tacrolimus also seems to reduce the production of several proteins that are involved in T-cell activation, as well as block the release of substances from mast cells and basophils. Finally, it may down-regulate the expression of FceRI on Langerh
When to interrupt dosage
The measure of Prograf is subject to the diagnosed condition, including Vitiligo, Rejection; Transplant, Kidney and Pyoderma Gangrenosum. The quantity of dosage deviates, depending on the procedure of delivery (e.g. Capsule, gelatin coated - Oral or Topical) indicated in the table below.Condition
Dosage
Administration
Heart
, 1.0 mg, 0.001 mg/mg, 0.5 mg, 0.03 %, 5.0 mg, 4.0 mg, 5.0 mg/mL, 0.2 mg, 0.003 mg/mg, 2.0 mg, 0.00003 mg/mg, 0.0003 mg/mg, 3.0 mg, 0.75 mg, 0.1 %, 5.0 mg/mg
Capsule, gelatin coated - Oral, Topical, , Capsule - Oral, Capsule, extended release - Oral, Ointment - Topical, Oral, Cream - Topical, Capsule, coated, extended release - Oral, Injection, solution - Intravenous, Tablet, extended release - Oral, Cutaneous, Capsule, Solution - Intravenous, Intravenous, Granule, Capsule, gelatin coated, Cream, Granule, for suspension - Oral, Solution, Granule, for suspension, Tablet, extended release, Ointment, Capsule, coated, extended release, Solution - Topical, Granule - Oral, Ointment - Cutaneous, Capsule, extended release, Kit, Injection, solution
Rejection; Transplant, Liver
, 1.0 mg, 0.001 mg/mg, 0.5 mg, 0.03 %, 5.0 mg, 4.0 mg, 5.0 mg/mL, 0.2 mg, 0.003 mg/mg, 2.0 mg, 0.00003 mg/mg, 0.0003 mg/mg, 3.0 mg, 0.75 mg, 0.1 %, 5.0 mg/mg
Capsule, gelatin coated - Oral, Topical, , Capsule - Oral, Capsule, extended release - Oral, Ointment - Topical, Oral, Cream - Topical, Capsule, coated, extended release - Oral, Injection, solution - Intravenous, Tablet, extended release - Oral, Cutaneous, Capsule, Solution - Intravenous, Intravenous, Granule, Capsule, gelatin coated, Cream, Granule, for suspension - Oral, Solution, Granule, for suspension, Tablet, extended release, Ointment, Capsule, coated, extended release, Solution - Topical, Granule - Oral, Ointment - Cutaneous, Capsule, extended release, Kit, Injection, solution
Prophylaxis against heart transplant rejection
, 1.0 mg, 0.001 mg/mg, 0.5 mg, 0.03 %, 5.0 mg, 4.0 mg, 5.0 mg/mL, 0.2 mg, 0.003 mg/mg, 2.0 mg, 0.00003 mg/mg, 0.0003 mg/mg, 3.0 mg, 0.75 mg, 0.1 %, 5.0 mg/mg
Capsule, gelatin coated - Oral, Topical, , Capsule - Oral, Capsule, extended release - Oral, Ointment - Topical, Oral, Cream - Topical, Capsule, coated, extended release - Oral, Injection, solution - Intravenous, Tablet, extended release - Oral, Cutaneous, Capsule, Solution - Intravenous, Intravenous, Granule, Capsule, gelatin coated, Cream, Granule, for suspension - Oral, Solution, Granule, for suspension, Tablet, extended release, Ointment, Capsule, coated, extended release, Solution - Topical, Granule - Oral, Ointment - Cutaneous, Capsule, extended release, Kit, Injection, solution
Dermatitis, Atopic
, 1.0 mg, 0.001 mg/mg, 0.5 mg, 0.03 %, 5.0 mg, 4.0 mg, 5.0 mg/mL, 0.2 mg, 0.003 mg/mg, 2.0 mg, 0.00003 mg/mg, 0.0003 mg/mg, 3.0 mg, 0.75 mg, 0.1 %, 5.0 mg/mg
Capsule, gelatin coated - Oral, Topical, , Capsule - Oral, Capsule, extended release - Oral, Ointment - Topical, Oral, Cream - Topical, Capsule, coated, extended release - Oral, Injection, solution - Intravenous, Tablet, extended release - Oral, Cutaneous, Capsule, Solution - Intravenous, Intravenous, Granule, Capsule, gelatin coated, Cream, Granule, for suspension - Oral, Solution, Granule, for suspension, Tablet, extended release, Ointment, Capsule, coated, extended release, Solution - Topical, Granule - Oral, Ointment - Cutaneous, Capsule, extended release, Kit, Injection, solution
Rheumatoid Arthritis
, 1.0 mg, 0.001 mg/mg, 0.5 mg, 0.03 %, 5.0 mg, 4.0 mg, 5.0 mg/mL, 0.2 mg, 0.003 mg/mg, 2.0 mg, 0.00003 mg/mg, 0.0003 mg/mg, 3.0 mg, 0.75 mg, 0.1 %, 5.0 mg/mg
Capsule, gelatin coated - Oral, Topical, , Capsule - Oral, Capsule, extended release - Oral, Ointment - Topical, Oral, Cream - Topical, Capsule, coated, extended release - Oral, Injection, solution - Intravenous, Tablet, extended release - Oral, Cutaneous, Capsule, Solution - Intravenous, Intravenous, Granule, Capsule, gelatin coated, Cream, Granule, for suspension - Oral, Solution, Granule, for suspension, Tablet, extended release, Ointment, Capsule, coated, extended release, Solution - Topical, Granule - Oral, Ointment - Cutaneous, Capsule, extended release, Kit, Injection, solution
Liver
, 1.0 mg, 0.001 mg/mg, 0.5 mg, 0.03 %, 5.0 mg, 4.0 mg, 5.0 mg/mL, 0.2 mg, 0.003 mg/mg, 2.0 mg, 0.00003 mg/mg, 0.0003 mg/mg, 3.0 mg, 0.75 mg, 0.1 %, 5.0 mg/mg
Capsule, gelatin coated - Oral, Topical, , Capsule - Oral, Capsule, extended release - Oral, Ointment - Topical, Oral, Cream - Topical, Capsule, coated, extended release - Oral, Injection, solution - Intravenous, Tablet, extended release - Oral, Cutaneous, Capsule, Solution - Intravenous, Intravenous, Granule, Capsule, gelatin coated, Cream, Granule, for suspension - Oral, Solution, Granule, for suspension, Tablet, extended release, Ointment, Capsule, coated, extended release, Solution - Topical, Granule - Oral, Ointment - Cutaneous, Capsule, extended release, Kit, Injection, solution
Rejection; Transplant, Kidney
, 1.0 mg, 0.001 mg/mg, 0.5 mg, 0.03 %, 5.0 mg, 4.0 mg, 5.0 mg/mL, 0.2 mg, 0.003 mg/mg, 2.0 mg, 0.00003 mg/mg, 0.0003 mg/mg, 3.0 mg, 0.75 mg, 0.1 %, 5.0 mg/mg
Capsule, gelatin coated - Oral, Topical, , Capsule - Oral, Capsule, extended release - Oral, Ointment - Topical, Oral, Cream - Topical, Capsule, coated, extended release - Oral, Injection, solution - Intravenous, Tablet, extended release - Oral, Cutaneous, Capsule, Solution - Intravenous, Intravenous, Granule, Capsule, gelatin coated, Cream, Granule, for suspension - Oral, Solution, Granule, for suspension, Tablet, extended release, Ointment, Capsule, coated, extended release, Solution - Topical, Granule - Oral, Ointment - Cutaneous, Capsule, extended release, Kit, Injection, solution
Dermatitis, Atopic
, 1.0 mg, 0.001 mg/mg, 0.5 mg, 0.03 %, 5.0 mg, 4.0 mg, 5.0 mg/mL, 0.2 mg, 0.003 mg/mg, 2.0 mg, 0.00003 mg/mg, 0.0003 mg/mg, 3.0 mg, 0.75 mg, 0.1 %, 5.0 mg/mg
Capsule, gelatin coated - Oral, Topical, , Capsule - Oral, Capsule, extended release - Oral, Ointment - Topical, Oral, Cream - Topical, Capsule, coated, extended release - Oral, Injection, solution - Intravenous, Tablet, extended release - Oral, Cutaneous, Capsule, Solution - Intravenous, Intravenous, Granule, Capsule, gelatin coated, Cream, Granule, for suspension - Oral, Solution, Granule, for suspension, Tablet, extended release, Ointment, Capsule, coated, extended release, Solution - Topical, Granule - Oral, Ointment - Cutaneous, Capsule, extended release, Kit, Injection, solution
Vitiligo
, 1.0 mg, 0.001 mg/mg, 0.5 mg, 0.03 %, 5.0 mg, 4.0 mg, 5.0 mg/mL, 0.2 mg, 0.003 mg/mg, 2.0 mg, 0.00003 mg/mg, 0.0003 mg/mg, 3.0 mg, 0.75 mg, 0.1 %, 5.0 mg/mg
Capsule, gelatin coated - Oral, Topical, , Capsule - Oral, Capsule, extended release - Oral, Ointment - Topical, Oral, Cream - Topical, Capsule, coated, extended release - Oral, Injection, solution - Intravenous, Tablet, extended release - Oral, Cutaneous, Capsule, Solution - Intravenous, Intravenous, Granule, Capsule, gelatin coated, Cream, Granule, for suspension - Oral, Solution, Granule, for suspension, Tablet, extended release, Ointment, Capsule, coated, extended release, Solution - Topical, Granule - Oral, Ointment - Cutaneous, Capsule, extended release, Kit, Injection, solution
Pyoderma Gangrenosum
, 1.0 mg, 0.001 mg/mg, 0.5 mg, 0.03 %, 5.0 mg, 4.0 mg, 5.0 mg/mL, 0.2 mg, 0.003 mg/mg, 2.0 mg, 0.00003 mg/mg, 0.0003 mg/mg, 3.0 mg, 0.75 mg, 0.1 %, 5.0 mg/mg
Capsule, gelatin coated - Oral, Topical, , Capsule - Oral, Capsule, extended release - Oral, Ointment - Topical, Oral, Cream - Topical, Capsule, coated, extended release - Oral, Injection, solution - Intravenous, Tablet, extended release - Oral, Cutaneous, Capsule, Solution - Intravenous, Intravenous, Granule, Capsule, gelatin coated, Cream, Granule, for suspension - Oral, Solution, Granule, for suspension, Tablet, extended release, Ointment, Capsule, coated, extended release, Solution - Topical, Granule - Oral, Ointment - Cutaneous, Capsule, extended release, Kit, Injection, solution
Kidney Transplantation
, 1.0 mg, 0.001 mg/mg, 0.5 mg, 0.03 %, 5.0 mg, 4.0 mg, 5.0 mg/mL, 0.2 mg, 0.003 mg/mg, 2.0 mg, 0.00003 mg/mg, 0.0003 mg/mg, 3.0 mg, 0.75 mg, 0.1 %, 5.0 mg/mg
Capsule, gelatin coated - Oral, Topical, , Capsule - Oral, Capsule, extended release - Oral, Ointment - Topical, Oral, Cream - Topical, Capsule, coated, extended release - Oral, Injection, solution - Intravenous, Tablet, extended release - Oral, Cutaneous, Capsule, Solution - Intravenous, Intravenous, Granule, Capsule, gelatin coated, Cream, Granule, for suspension - Oral, Solution, Granule, for suspension, Tablet, extended release, Ointment, Capsule, coated, extended release, Solution - Topical, Granule - Oral, Ointment - Cutaneous, Capsule, extended release, Kit, Injection, solution
Rheumatoid Arthritis
, 1.0 mg, 0.001 mg/mg, 0.5 mg, 0.03 %, 5.0 mg, 4.0 mg, 5.0 mg/mL, 0.2 mg, 0.003 mg/mg, 2.0 mg, 0.00003 mg/mg, 0.0003 mg/mg, 3.0 mg, 0.75 mg, 0.1 %, 5.0 mg/mg
Capsule, gelatin coated - Oral, Topical, , Capsule - Oral, Capsule, extended release - Oral, Ointment - Topical, Oral, Cream - Topical, Capsule, coated, extended release - Oral, Injection, solution - Intravenous, Tablet, extended release - Oral, Cutaneous, Capsule, Solution - Intravenous, Intravenous, Granule, Capsule, gelatin coated, Cream, Granule, for suspension - Oral, Solution, Granule, for suspension, Tablet, extended release, Ointment, Capsule, coated, extended release, Solution - Topical, Granule - Oral, Ointment - Cutaneous, Capsule, extended release, Kit, Injection, solution
Psoriasis
, 1.0 mg, 0.001 mg/mg, 0.5 mg, 0.03 %, 5.0 mg, 4.0 mg, 5.0 mg/mL, 0.2 mg, 0.003 mg/mg, 2.0 mg, 0.00003 mg/mg, 0.0003 mg/mg, 3.0 mg, 0.75 mg, 0.1 %, 5.0 mg/mg
Capsule, gelatin coated - Oral, Topical, , Capsule - Oral, Capsule, extended release - Oral, Ointment - Topical, Oral, Cream - Topical, Capsule, coated, extended release - Oral, Injection, solution - Intravenous, Tablet, extended release - Oral, Cutaneous, Capsule, Solution - Intravenous, Intravenous, Granule, Capsule, gelatin coated, Cream, Granule, for suspension - Oral, Solution, Granule, for suspension, Tablet, extended release, Ointment, Capsule, coated, extended release, Solution - Topical, Granule - Oral, Ointment - Cutaneous, Capsule, extended release, Kit, Injection, solution
Oral Lichen Planus
, 1.0 mg, 0.001 mg/mg, 0.5 mg, 0.03 %, 5.0 mg, 4.0 mg, 5.0 mg/mL, 0.2 mg, 0.003 mg/mg, 2.0 mg, 0.00003 mg/mg, 0.0003 mg/mg, 3.0 mg, 0.75 mg, 0.1 %, 5.0 mg/mg
Capsule, gelatin coated - Oral, Topical, , Capsule - Oral, Capsule, extended release - Oral, Ointment - Topical, Oral, Cream - Topical, Capsule, coated, extended release - Oral, Injection, solution - Intravenous, Tablet, extended release - Oral, Cutaneous, Capsule, Solution - Intravenous, Intravenous, Granule, Capsule, gelatin coated, Cream, Granule, for suspension - Oral, Solution, Granule, for suspension, Tablet, extended release, Ointment, Capsule, coated, extended release, Solution - Topical, Granule - Oral, Ointment - Cutaneous, Capsule, extended release, Kit, Injection, solution
Chronic Graft Versus Host Disease
, 1.0 mg, 0.001 mg/mg, 0.5 mg, 0.03 %, 5.0 mg, 4.0 mg, 5.0 mg/mL, 0.2 mg, 0.003 mg/mg, 2.0 mg, 0.00003 mg/mg, 0.0003 mg/mg, 3.0 mg, 0.75 mg, 0.1 %, 5.0 mg/mg
Capsule, gelatin coated - Oral, Topical, , Capsule - Oral, Capsule, extended release - Oral, Ointment - Topical, Oral, Cream - Topical, Capsule, coated, extended release - Oral, Injection, solution - Intravenous, Tablet, extended release - Oral, Cutaneous, Capsule, Solution - Intravenous, Intravenous, Granule, Capsule, gelatin coated, Cream, Granule, for suspension - Oral, Solution, Granule, for suspension, Tablet, extended release, Ointment, Capsule, coated, extended release, Solution - Topical, Granule - Oral, Ointment - Cutaneous, Capsule, extended release, Kit, Injection, solution
Dermatitis, Atopic
, 1.0 mg, 0.001 mg/mg, 0.5 mg, 0.03 %, 5.0 mg, 4.0 mg, 5.0 mg/mL, 0.2 mg, 0.003 mg/mg, 2.0 mg, 0.00003 mg/mg, 0.0003 mg/mg, 3.0 mg, 0.75 mg, 0.1 %, 5.0 mg/mg
Capsule, gelatin coated - Oral, Topical, , Capsule - Oral, Capsule, extended release - Oral, Ointment - Topical, Oral, Cream - Topical, Capsule, coated, extended release - Oral, Injection, solution - Intravenous, Tablet, extended release - Oral, Cutaneous, Capsule, Solution - Intravenous, Intravenous, Granule, Capsule, gelatin coated, Cream, Granule, for suspension - Oral, Solution, Granule, for suspension, Tablet, extended release, Ointment, Capsule, coated, extended release, Solution - Topical, Granule - Oral, Ointment - Cutaneous, Capsule, extended release, Kit, Injection, solution
refractory Rheumatoid arthritis
, 1.0 mg, 0.001 mg/mg, 0.5 mg, 0.03 %, 5.0 mg, 4.0 mg, 5.0 mg/mL, 0.2 mg, 0.003 mg/mg, 2.0 mg, 0.00003 mg/mg, 0.0003 mg/mg, 3.0 mg, 0.75 mg, 0.1 %, 5.0 mg/mg
Capsule, gelatin coated - Oral, Topical, , Capsule - Oral, Capsule, extended release - Oral, Ointment - Topical, Oral, Cream - Topical, Capsule, coated, extended release - Oral, Injection, solution - Intravenous, Tablet, extended release - Oral, Cutaneous, Capsule, Solution - Intravenous, Intravenous, Granule, Capsule, gelatin coated, Cream, Granule, for suspension - Oral, Solution, Granule, for suspension, Tablet, extended release, Ointment, Capsule, coated, extended release, Solution - Topical, Granule - Oral, Ointment - Cutaneous, Capsule, extended release, Kit, Injection, solution
Warnings
Prograf has one contraindication, meaning that it should not be employed while encountering the conditions listed in the following table.Prograf ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Tacrolimus may interact with Toxoplasma Infections
Common Prograf Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The serum concentration of Abemaciclib can be increased when it is combined with Tacrolimus.
Alectinib
Major
The metabolism of Alectinib can be decreased when combined with Tacrolimus.
Aminophylline
Major
The metabolism of Aminophylline can be decreased when combined with Tacrolimus.
Axitinib
Major
The serum concentration of Axitinib can be increased when it is combined with Tacrolimus.
Bacillus calmette-guerin substrain russian BCG-I live antigen
Major
The therapeutic efficacy of Bacillus calmette-guerin substrain russian BCG-I live antigen can be decreased when used in combination with Tacrolimus.
Prograf Toxicity & Overdose RiskTaking too much of this drug can lead to blurred vision, kidney and liver damage, seizures, trembling, high blood pressure, low levels of magnesium, diabetes, high levels of potassium, itching, difficulty sleeping, and confusion. The lowest toxic dose in rats is 134-194mg/kg.
Prograf Novel Uses: Which Conditions Have a Clinical Trial Featuring Prograf?
147 active research studies are currently being conducted to assess the potential of Prograf to alleviate Oral Lichen Planus, Pyoderma Gangrenosum and refractory Rheumatoid Arthritis.Condition
Clinical Trials
Trial Phases
Psoriasis
0 Actively Recruiting
Rheumatoid Arthritis
62 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1
Oral Lichen Planus
0 Actively Recruiting
Dermatitis, Atopic
0 Actively Recruiting
Kidney Transplantation
0 Actively Recruiting
Rejection; Transplant, Liver
0 Actively Recruiting
refractory Rheumatoid arthritis
0 Actively Recruiting
Dermatitis, Atopic
0 Actively Recruiting
Pyoderma Gangrenosum
2 Actively Recruiting
Early Phase 1, Phase 3
Rejection; Transplant, Kidney
10 Actively Recruiting
Phase 3, Phase 1, Phase 2, Phase 4, Not Applicable, Early Phase 1
Vitiligo
11 Actively Recruiting
Phase 2, Phase 3, Not Applicable
Heart
2 Actively Recruiting
Phase 2, Not Applicable
Chronic Graft Versus Host Disease
32 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4, Phase 3, Early Phase 1
Liver
0 Actively Recruiting
Dermatitis, Atopic
0 Actively Recruiting
Rheumatoid Arthritis
0 Actively Recruiting
Prophylaxis against heart transplant rejection
0 Actively Recruiting
Prograf Reviews: What are patients saying about Prograf?
5Patient Review
5/21/2014 I had a kidney transplant about a year ago and have been taking Prograf since. My creatinine levels have always stayed stable between 1.3 and 1.4. But, for the last three months I've been taking Tracolimus (the generic version) and my creatinine has risen from 1.5 to 1.7. Has anyone else experienced this? Or does anyone know if this could be the problem?
5Patient Review
8/16/2015 So far, I'm five weeks in and feeling good. There was a little bit of initial adjustments needed for the first hour or two, but since then it's been fine. No rejections thus far, touch wood.
5Patient Review
2/13/2015 Though I experienced a range of side effects, like hair loss, tingling, blurred vision and insomnia, I'm thankful that this treatment didn't negatively impact my liver.
4.7Patient Review
8/2/2015 It's only been three months since my liver transplant, and I was already on dialysis. However, after just six weeks I had a fever of 100.3. They found an infection in my blood.
4.7Patient Review
1/29/2017 Prograf has been a life-saver for me. I had a liver transplant when I was two and a half, and have been on Prograf ever since. It's tough on my kidneys, which causes me to have high blood pressure, but I'm also taking another medication to help with that. This New Year's Eve will be my 12th "liver-versary", and I credit Prograf (along with a few other drugs) for keeping me alive all this time.
4.7Patient Review
6/28/2016 For those of you who are struggling with this treatment, I just want to let you know that in most cases the doctor can switch you back to the brand name if generic is causing problems. And for those of you who have only recently started this medication, please be aware that many side effects will dissipate over time and your hair may even grow back thicker than before. This is my second transplant and I feel very lucky.
4.7Patient Review
11/22/2017 The transplant went great and I only have one complaint 13 months later. The prograf has caused some shaking and trembling in my hands.
4.7Patient Review
4/24/20144.3Patient Review
4/25/2014 I underwent a liver transplant in 2010 due to cancer caused by Hepatitis B. I've been taking Prograf since the day of my surgery, and I'm now down to 1mg twice a day. The only side effects I've experienced are high blood pressure and cold hands, which are both minor compared to the alternative.
4.3Patient Review
6/26/2016 I had a double organ transplant on 1/15/2014 and it's going great. I'm 20 months post-op and feeling stronger every day.
4.3Patient Review
3/16/20144.3Patient Review
6/8/2014 I'm very pleased with this transplant. It's been six months and I haven't had any issues whatsoever.
4Patient Review
4/13/2015 I've been on the Prograf and Cellcept combo for thirteen years, next week. I have diabetes as a result (but it's well-controlled), and I've had to remove some bad skin cells. I also have to urinate frequently, but that's a small price to pay for being alive today.
4Patient Review
11/21/2017 This medication caused my hair to fall out and also made me shake.
3.7Patient Review
5/29/2015 Lots of side effects - tremors in hands and feet, but worse - loss of hair.
3.7Patient Review
6/28/2014 I've had to deal with some pretty severe side-effects from this medication, but it's been worth it for the almost ten years that I've been able to tolerate it. My doctor is careful and attentive, which makes all the difference.
3.3Patient Review
8/4/2014 I've been taking this medication for nearly a decade and, while there are some side effects that come with it (e.g. shaking hands), it's still better than the alternative treatments out there.
Patient Q&A Section about prograf
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Prograf used to treat?
"Tacrolimus is a drug that suppresses the immune system and is used to prevent organ rejection in children who have had liver transplants."
Answered by AI
Is Prograf an immunosuppressant?
"Today's decision represents the first time an immunosuppressant drug has been approved to prevent rejection in adult and pediatric patients who receive lung transplants. Prograf is the only drug product of its kind that has been approved for this population."
Answered by AI
What are the side effects for Prograf?
"The most common adverse reactions (occurring in more than 40% of PROGRAF-treated liver transplant patients) include: tremor, headache, diarrhea, hypertension, nausea, abnormal renal function, abdominal pain, insomnia, paresthesia, anemia, pain, fever, asthenia, hyperkalemia, hypomagnesemia, and hyperglycemia."
Answered by AI
Is Prograf a steroid?
"Tacrolimus (Prograf) does not belong to the class of drugs called steroids or corticosteroids. Sometimes, corticosteroids and calcineurin inhibitors are used together to prevent transplant rejections."
Answered by AI