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ANAVEX2-73 for Alzheimer's Disease (ATTENTION-AD Trial)

Phase 2 & 3
Waitlist Available
Research Sponsored by Anavex Life Sciences Corp.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 96 weeks
Awards & highlights

ATTENTION-AD Trial Summary

This trial is testing a new drug to see if it is safe and effective when taken every day.

Who is the study for?
This trial is for those who completed the ANAVEX2-73-AD-004 study, can be outpatients or in assisted living, and have a partner to help with assessments. They must not have severe suicidal thoughts or behaviors recently and women of childbearing age must not be pregnant.Check my eligibility
What is being tested?
The trial tests the long-term safety and effectiveness of ANAVEX2-73 when taken daily by people with Alzheimer's Disease who participated in a prior related study.See study design
What are the potential side effects?
Specific side effects are not listed here, but participants from the previous study cannot join if they had moderate to severe adverse events possibly related to ANAVEX2-73 that haven't resolved.

ATTENTION-AD Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~96 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 96 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of participants with treatment-related adverse events as assessed by CTCAE v4.03
Secondary outcome measures
ADAS-Cog (Alzheimer Disease Assessment Scale-Cognition)
ADCS-ADL (Activities of Daily Living)

ATTENTION-AD Trial Design

1Treatment groups
Experimental Treatment
Group I: ActiveExperimental Treatment1 Intervention
ANAVEX2-73
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
ANAVEX2-73
2019
Completed Phase 3
~220

Find a Location

Who is running the clinical trial?

Anavex Life Sciences Corp.Lead Sponsor
12 Previous Clinical Trials
1,252 Total Patients Enrolled
Anavex Australia Pty Ltd.Industry Sponsor
4 Previous Clinical Trials
769 Total Patients Enrolled
Anavex Germany GmbHIndustry Sponsor
4 Previous Clinical Trials
865 Total Patients Enrolled

Media Library

ANAVEX2-73 (Other) Clinical Trial Eligibility Overview. Trial Name: NCT04314934 — Phase 2 & 3
Alzheimer's Disease Research Study Groups: Active
Alzheimer's Disease Clinical Trial 2023: ANAVEX2-73 Highlights & Side Effects. Trial Name: NCT04314934 — Phase 2 & 3
ANAVEX2-73 (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04314934 — Phase 2 & 3

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are the test subjects in this trial restricted to those over the age of 20?

"This study is investigating whether the experimental treatment is effective for patients that are aged 55 to 85."

Answered by AI

Are there multiple sites running this clinical trial in this city?

"The Toronto Memory Program, Bay Crest Health Sciences, Kawartha Centre, and 5 other locations are currently running this clinical trial."

Answered by AI

What other medical research has there been on ANAVEX2-73?

"ANAVEX2-73 was first researched in 2019 by MAC Clinical Research. Since then, there have been 4 completed trials and presently there are 2 studies actively recruiting patients. The majority of these studies are located in Toronto, Alberta."

Answered by AI

This study is helping how many people?

"That is correct. The online clinicaltrials.gov registry reflects that this study is still recruiting patients. This study was first advertised on October 10th, 2019 and was updated as recently as July 12th, 2022. There are currently 5 sites where this trial is taking place and a total of 450 patients are desired."

Answered by AI

What groundbreaking discoveries can be expected from this research?

"ANAVEX2-73 has been under clinical investigation since 2019. The first trial, sponsored by Anavex Germany GmbH, took place that year and included 450 participants. After the initial study in 2019, ANAVEX2-73 received Phase 2 & 3 drug approval. As of now, there are 2 live studies for ANAVEX2-73 being conducted in 32 cities across 5 countries."

Answered by AI

Could I be a subject in this experiment?

"Alzheimer's disease patients that are aged between 55 and 85 can apply to be a part of this clinical trial. The goal is to have around 450 participants."

Answered by AI
~16 spots leftby Jul 2024