Orapred

Ophthalmia, Sympathetic, Collagen Diseases, Uveitis + 12 more
Treatment
24 FDA approvals
20 Active Studies for Orapred

What is Orapred

Prednisolone phosphateThe Generic name of this drug
Treatment SummaryPrednisolone phosphate is a steroid medication used to reduce inflammation and suppress the immune system. It is also used to treat certain types of tumors. The drug was approved by the FDA in 1973 and can produce effects such as constricting blood vessels.
Pediapredis the brand name
image of different drug pills on a surface
Orapred Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Pediapred
Prednisolone phosphate
1986
71

Approved as Treatment by the FDA

Prednisolone phosphate, also called Pediapred, is approved by the FDA for 24 uses such as Conjunctivitis and Uveitis .
Conjunctivitis
Uveitis
Endocrine System Diseases
Giant Cell Arteritis
Skin Diseases
Hypersensitivity
Multiple Sclerosis
Neoplastic Disease
Temporal Arteritis
Swollen feet or ankles
Disease
Collagen Diseases
Endocrine Disorders
Allergic Conditions
Respiratory Diseases
Ocular Inflammation
Uveitis
Ophthalmia, Sympathetic
Multiple sclerosis exacerbation
Dermatological Disease
Gastroenteritis
Uveitis
Edema
Gastrointestinal Diseases

Effectiveness

How Orapred Affects PatientsPrednisolone works by blocking certain signals in the body that can lead to inflammation. It is only active in the body for a short time (2-4 hours), but the amount prescribed can be much higher than what the body makes naturally. People taking prednisolone should be aware of the risk of suppressing the body's hormone system and becoming more vulnerable to infections.
How Orapred works in the bodyCorticosteroids work to reduce inflammation in the body. They do this by affecting the flow of blood vessels and blocking white blood cells from travelling to sites of inflammation. Corticosteroids also change how certain genes are expressed, causing anti-inflammatory effects. Low doses reduce inflammation while high doses weaken the immune system. If taken for a long time, corticosteroids can cause an increase in sodium and decrease in potassium levels.

When to interrupt dosage

The proposed dosage of Orapred is contingent upon the indicated affliction, including Uveitis, Ocular Inflammation and Ophthalmia, Sympathetic. The measure of dosage is set by the method of administration specified in the table below.
Condition
Dosage
Administration
Collagen Diseases
15.0 mg/mL, , 25.0 mg/mL, 10.0 mg, 15.0 mg, 30.0 mg, 10.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 20.0 mg/mL, 1.0 %, 0.125 %, 0.5 %, 2.3 mg/mL, 1.25 mg/mL
, Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Liquid; Solution / drops, Liquid; Solution / drops - Ophthalmic, Liquid - Oral
Multiple Sclerosis
15.0 mg/mL, , 25.0 mg/mL, 10.0 mg, 15.0 mg, 30.0 mg, 10.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 20.0 mg/mL, 1.0 %, 0.125 %, 0.5 %, 2.3 mg/mL, 1.25 mg/mL
, Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Liquid; Solution / drops, Liquid; Solution / drops - Ophthalmic, Liquid - Oral
Respiratory Diseases
15.0 mg/mL, , 25.0 mg/mL, 10.0 mg, 15.0 mg, 30.0 mg, 10.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 20.0 mg/mL, 1.0 %, 0.125 %, 0.5 %, 2.3 mg/mL, 1.25 mg/mL
, Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Liquid; Solution / drops, Liquid; Solution / drops - Ophthalmic, Liquid - Oral
Skin Diseases
15.0 mg/mL, , 25.0 mg/mL, 10.0 mg, 15.0 mg, 30.0 mg, 10.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 20.0 mg/mL, 1.0 %, 0.125 %, 0.5 %, 2.3 mg/mL, 1.25 mg/mL
, Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Liquid; Solution / drops, Liquid; Solution / drops - Ophthalmic, Liquid - Oral
Swollen feet or ankles
15.0 mg/mL, , 25.0 mg/mL, 10.0 mg, 15.0 mg, 30.0 mg, 10.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 20.0 mg/mL, 1.0 %, 0.125 %, 0.5 %, 2.3 mg/mL, 1.25 mg/mL
, Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Liquid; Solution / drops, Liquid; Solution / drops - Ophthalmic, Liquid - Oral
Disease
15.0 mg/mL, , 25.0 mg/mL, 10.0 mg, 15.0 mg, 30.0 mg, 10.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 20.0 mg/mL, 1.0 %, 0.125 %, 0.5 %, 2.3 mg/mL, 1.25 mg/mL
, Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Liquid; Solution / drops, Liquid; Solution / drops - Ophthalmic, Liquid - Oral
Endocrine System Diseases
15.0 mg/mL, , 25.0 mg/mL, 10.0 mg, 15.0 mg, 30.0 mg, 10.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 20.0 mg/mL, 1.0 %, 0.125 %, 0.5 %, 2.3 mg/mL, 1.25 mg/mL
, Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Liquid; Solution / drops, Liquid; Solution / drops - Ophthalmic, Liquid - Oral
Uveitis
15.0 mg/mL, , 25.0 mg/mL, 10.0 mg, 15.0 mg, 30.0 mg, 10.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 20.0 mg/mL, 1.0 %, 0.125 %, 0.5 %, 2.3 mg/mL, 1.25 mg/mL
, Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Liquid; Solution / drops, Liquid; Solution / drops - Ophthalmic, Liquid - Oral
Urinary Tract Infection (UTI)
15.0 mg/mL, , 25.0 mg/mL, 10.0 mg, 15.0 mg, 30.0 mg, 10.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 20.0 mg/mL, 1.0 %, 0.125 %, 0.5 %, 2.3 mg/mL, 1.25 mg/mL
, Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Liquid; Solution / drops, Liquid; Solution / drops - Ophthalmic, Liquid - Oral
Conjunctivitis
15.0 mg/mL, , 25.0 mg/mL, 10.0 mg, 15.0 mg, 30.0 mg, 10.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 20.0 mg/mL, 1.0 %, 0.125 %, 0.5 %, 2.3 mg/mL, 1.25 mg/mL
, Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Liquid; Solution / drops, Liquid; Solution / drops - Ophthalmic, Liquid - Oral
Giant Cell Arteritis
15.0 mg/mL, , 25.0 mg/mL, 10.0 mg, 15.0 mg, 30.0 mg, 10.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 20.0 mg/mL, 1.0 %, 0.125 %, 0.5 %, 2.3 mg/mL, 1.25 mg/mL
, Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Liquid; Solution / drops, Liquid; Solution / drops - Ophthalmic, Liquid - Oral
Gastroenteritis
15.0 mg/mL, , 25.0 mg/mL, 10.0 mg, 15.0 mg, 30.0 mg, 10.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 20.0 mg/mL, 1.0 %, 0.125 %, 0.5 %, 2.3 mg/mL, 1.25 mg/mL
, Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Liquid; Solution / drops, Liquid; Solution / drops - Ophthalmic, Liquid - Oral
Hypersensitivity
15.0 mg/mL, , 25.0 mg/mL, 10.0 mg, 15.0 mg, 30.0 mg, 10.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 20.0 mg/mL, 1.0 %, 0.125 %, 0.5 %, 2.3 mg/mL, 1.25 mg/mL
, Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Liquid; Solution / drops, Liquid; Solution / drops - Ophthalmic, Liquid - Oral
Ophthalmia, Sympathetic
15.0 mg/mL, , 25.0 mg/mL, 10.0 mg, 15.0 mg, 30.0 mg, 10.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 20.0 mg/mL, 1.0 %, 0.125 %, 0.5 %, 2.3 mg/mL, 1.25 mg/mL
, Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Liquid; Solution / drops, Liquid; Solution / drops - Ophthalmic, Liquid - Oral
Neoplastic Disease
15.0 mg/mL, , 25.0 mg/mL, 10.0 mg, 15.0 mg, 30.0 mg, 10.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 20.0 mg/mL, 1.0 %, 0.125 %, 0.5 %, 2.3 mg/mL, 1.25 mg/mL
, Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Liquid; Solution / drops, Liquid; Solution / drops - Ophthalmic, Liquid - Oral

Warnings

Orapred has one contraindication and should not be consummated together with the conditions given in the following table.Orapred Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Prednisolone Phosphate may interact with Pulse Frequency
There are 20 known major drug interactions with Orapred.
Common Orapred Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The serum concentration of Abemaciclib can be decreased when it is combined with Prednisolone phosphate.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Prednisolone phosphate.
Aldesleukin
Major
The therapeutic efficacy of Aldesleukin can be decreased when used in combination with Prednisolone phosphate.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Prednisolone phosphate.
Alpelisib
Major
The metabolism of Alpelisib can be increased when combined with Prednisolone phosphate.
Orapred Toxicity & Overdose RiskNot much is known about acute Glucocorticoid overdose. Chronic overdose, however, can cause mental symptoms, a round face, fat deposits, and water retention. In case of an acute overdose, the patient should be given their stomach contents to vomit or have it removed with a tube, followed by supportive treatment. If the overdose is chronic, the dose should be reduced temporarily or taken every other day.
image of a doctor in a lab doing drug, clinical research

Orapred Novel Uses: Which Conditions Have a Clinical Trial Featuring Orapred?

115 active clinical trials are currently underway to assess the potential of Orapred to ameliorate Ocular Inflammation, Uveitis and Sympathetic Ophthalmia.
Condition
Clinical Trials
Trial Phases
Uveitis
2 Actively Recruiting
Not Applicable, Phase 3
Giant Cell Arteritis
0 Actively Recruiting
Conjunctivitis
0 Actively Recruiting
Disease
0 Actively Recruiting
Urinary Tract Infection (UTI)
9 Actively Recruiting
Phase 1, Phase 3, Phase 4, Not Applicable
Swollen feet or ankles
7 Actively Recruiting
Phase 2, Not Applicable
Endocrine System Diseases
0 Actively Recruiting
Multiple Sclerosis
0 Actively Recruiting
Skin Diseases
1 Actively Recruiting
Phase 2
Gastroenteritis
5 Actively Recruiting
Not Applicable
Respiratory Diseases
5 Actively Recruiting
Not Applicable
Collagen Diseases
10 Actively Recruiting
Not Applicable, Phase 4, Phase 1, Phase 3
Ophthalmia, Sympathetic
0 Actively Recruiting
Hypersensitivity
0 Actively Recruiting
Neoplastic Disease
1 Actively Recruiting
Phase 1

Orapred Reviews: What are patients saying about Orapred?

4.3Patient Review
6/11/2013
Orapred for Asthma
My daughter experienced some muscle soreness after taking this medication. It was bad enough that it was uncomfortable for her to even be touched.
4Patient Review
1/23/2010
Orapred for Asthma
I've been very pleased with this medication for my child's asthma. They don't become as hyperactive, which was a problem we experienced when using albuterol alone. The only downsides are that they sweat more and have increased appetite/thirst, but those are manageable compared to the benefits.
4Patient Review
5/31/2009
Orapred for Cancer of the Prostate Gland
This cough medicine was really effective for my son.
3.7Patient Review
6/7/2011
Orapred for Vocal Cord Swelling
Orapred has been effective at stopping my son's cough from croup, but he experiences severe side effects like crying and rubbing his eyes and ears obsessively. I'm glad it's only a 3 day course.
3.7Patient Review
11/29/2009
Orapred for Rash
My child became more hyperactive and began to hallucinate about bugs after taking this medication. Even though it got rid of the poison ivy, I would not recommend it for children.
View All Reviews

Patient Q&A Section about orapred

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Orapred an antibiotic?

"This prescription drug is used to help with swelling that comes from a lot of different illnesses. Some examples of these illnesses are arthritis, joint pain, psoriasis, colitis, leukemia, and allergies."

Answered by AI

Is Orapred a steroid?

"Orapred ODT is a medicine that contains the active ingredient prednisolone, which is a type of medicine known as a corticosteroid. Corticosteroids are medicines that are used to help reduce inflammation in the body."

Answered by AI

Is Orapred the same as prednisone?

"Prednisone and prednisolone are man-made steroids that are similar to cortisol, a hormone that your body produces naturally.

Brand names of prednisone include Prednisone Intensol and Rayos. Brand names of prednisolone include Flo-Pred, Pediapred, Orapred, and Orapred ODT. Prednisone and prednisolone are man-made steroids that are similar to cortisol. Both drugs are used to treat a variety of conditions, including allergies, autoimmune diseases, and skin conditions."

Answered by AI

What is Orapred used for?

"This drug is used to treat a variety of conditions that involve inflammation or an overactive immune system, including arthritis, blood disorders, skin and eye conditions, breathing problems, cancer, and severe allergies. It works by depressing the immune system, which decreases the inflammatory response and relieves symptoms such as pain, swelling, and allergic reactions."

Answered by AI

Clinical Trials for Orapred

Have you considered Orapred clinical trials? We made a collection of clinical trials featuring Orapred, we think they might fit your search criteria.
Have you considered Orapred clinical trials? We made a collection of clinical trials featuring Orapred, we think they might fit your search criteria.
Have you considered Orapred clinical trials? We made a collection of clinical trials featuring Orapred, we think they might fit your search criteria.
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