Nortrel 7/7/7

Endometriosis, Low Testosterone, Osteoporosis + 16 more
Treatment
20 Active Studies for Nortrel 7/7/7

What is Nortrel 7/7/7

NorethisteroneThe Generic name of this drug
Treatment SummaryNorethisterone (norethindrone) is a synthetic hormone used to treat menstrual irregularities, endometriosis, and other hormonal issues. It is classified as a second-generation progestin and is more potent than natural progesterone. It can be used alone or with estrogen to provide contraceptive and hormone replacement therapy. This drug was first created in 1951 and was approved for use as an oral contraceptive in 1962.
Neconis the brand name
image of different drug pills on a surface
Nortrel 7/7/7 Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Necon
Norethisterone
1967
347

Effectiveness

How Nortrel 7/7/7 Affects PatientsNorethisterone is a type of synthetic hormone taken by mouth. It can be used for birth control or to treat conditions related to hormones, like menopausal symptoms and endometriosis. Norethisterone acts like natural progesterone, but is more powerful. It changes cervical and endometrial function in the pelvic area and stops the hormones in the pituitary gland that help create eggs. There is a slight increased risk of getting breast cancer when taking oral contraceptives with progestins like norethisterone, so patients should be aware of this risk and do regular breast self-exams.
How Nortrel 7/7/7 works in the bodyNorethisterone works on target cells in the reproductive tract, breast, pituitary, hypothalamus, skeletal tissue, and central nervous system. It thickens cervical mucous to prevent sperm from entering the uterus. It also makes the uterus inhospitable for implantation and suppresses hormones from the pituitary gland that are needed for ovulation. When used with hormone therapy for menopausal women, it protects against endometrial hyperplasia. Norethisterone does not work on other steroid receptors, but it does have some androgen receptor agonism, which can cause side effects like acne and changes in serum

When to interrupt dosage

The proposed dose of Nortrel 7/7/7 is contingent upon the declared disorder, including Atrophic, Fracture and Hormone Replacement Therapy. The amount of dosage is contingent upon the form of delivery (e.g. Oral or Tablet) listed in the table beneath.
Condition
Dosage
Administration
Hot flashes
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Hormone Replacement Therapy
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Atrophic
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
female castration
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Low Testosterone
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
hypoestrogenism
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Therapeutic procedure
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Fracture
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Ovarian Failure
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Postmenopausal Osteoporosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Vasomotor System
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Oral Contraceptives
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Hormonal Contraception
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Estrogen Deprivation Symptoms
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Menopause
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Endometriosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Birth Control
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Osteoporosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Endometriosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Warnings

Nortrel 7/7/7 Contraindications
Condition
Risk Level
Notes
active liver disease
Do Not Combine
Thrombophilia
Do Not Combine
Vaginal Hemorrhage
Do Not Combine
Malignant Neoplasms
Do Not Combine
Benign hepatic neoplasm
Do Not Combine
Breast Cancer
Do Not Combine
Thromboembolism
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Norethisterone may interact with Pulse Frequency
There are 20 known major drug interactions with Nortrel 7/7/7.
Common Nortrel 7/7/7 Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Norethisterone.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Norethisterone.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Norethisterone.
Clomipramine
Major
The metabolism of Clomipramine can be increased when combined with Norethisterone.
Copanlisib
Major
The metabolism of Copanlisib can be decreased when combined with Norethisterone.
Nortrel 7/7/7 Toxicity & Overdose RiskThe lowest toxic dose of oral contraceptives in mice is 6g/kg and in women is 42mg/kg. No serious health problems have been reported from overdosing on oral contraceptives, including in children. Symptoms of an overdose may include severe nausea and vomiting.
image of a doctor in a lab doing drug, clinical research

Nortrel 7/7/7 Novel Uses: Which Conditions Have a Clinical Trial Featuring Nortrel 7/7/7?

160 active clinical trials are currently investigating the use of Nortrel 7/7/7 to provide Birth Control, Atrophic Uterine Changes and Low Testosterone Therapy.
Condition
Clinical Trials
Trial Phases
Estrogen Deprivation Symptoms
0 Actively Recruiting
Hot flashes
22 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 4, Early Phase 1
Oral Contraceptives
2 Actively Recruiting
Not Applicable
Therapeutic procedure
0 Actively Recruiting
Low Testosterone
15 Actively Recruiting
Phase 1, Phase 4, Phase 2, Not Applicable
Menopause
0 Actively Recruiting
Hormone Replacement Therapy
0 Actively Recruiting
Atrophic
5 Actively Recruiting
Phase 2, Phase 4, Not Applicable
Endometriosis
32 Actively Recruiting
Phase 3, Not Applicable, Early Phase 1, Phase 2, Phase 4, Phase 1
Osteoporosis
40 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 4, Phase 3
Postmenopausal Osteoporosis
3 Actively Recruiting
Not Applicable, Phase 4
Birth Control
31 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Early Phase 1
Fracture
0 Actively Recruiting
female castration
0 Actively Recruiting
hypoestrogenism
2 Actively Recruiting
Phase 4
Vasomotor System
0 Actively Recruiting
Endometriosis
1 Actively Recruiting
Phase 4
Ovarian Failure
2 Actively Recruiting
Not Applicable, Phase 1
Hormonal Contraception
0 Actively Recruiting

Nortrel 7/7/7 Reviews: What are patients saying about Nortrel 7/7/7?

5Patient Review
6/3/2011
Nortrel 7/7/7 for Painful Periods
I've been using this for a while now and it's really helped with my acne and period pain.
5Patient Review
1/5/2011
Nortrel 7/7/7 for Abnormally Long or Heavy Periods
This birth control has been much more effective for me in terms of managing my pain and mood swings. I would highly recommend it to other women who are struggling with similar issues.
5Patient Review
9/7/2011
Nortrel 7/7/7 for Birth Control
I was on Nortrel 777 for five years and loved it-- no complaints. I got pregnant the month after I stopped taking it, so there's definitely no worry about not being able to get pregnant after taking it. I recommend this pill to anyone!
5Patient Review
1/4/2011
Nortrel 7/7/7 for Birth Control
I've been using Nortrel for contraception for several years now, and I'm really happy with it. We got pregnant within two months of trying when we decided to have a baby, and I had no problems with conception or pregnancy.
5Patient Review
9/27/2018
Nortrel 7/7/7 for Birth Control
I have found that this treatment has helped to lighten my period, clear up my acne, and decrease my PMS symptoms. I have not experienced any negative side effects, such as weight gain or pregnancy.
5Patient Review
6/17/2016
Nortrel 7/7/7 for Abnormally Long or Heavy Periods
As a teenager, I had the worst cramps and my periods would last longer than 7 days. When I began taking them, my periods are now 3-4 days and my acne is no longer there.
5Patient Review
7/17/2017
Nortrel 7/7/7 for Birth Control
I've been very pleased with this birth control pill. It's the first one I've tried, and I haven't experienced any negative side effects. The only downside is that I have to remember to take it every day.
4.3Patient Review
1/2/2014
Nortrel 7/7/7 for Absence of Menstrual Periods
I was on this pill for about 6 months and during that time period I either had a very light period or no period at all. One issue I had with it was when I had just started taking it and the period after it was excruciating. It also cleared up my acne quite a bit. I really recommend this pill.
4.3Patient Review
8/15/2012
Nortrel 7/7/7 for Painful Periods
I've been using this birth control for three months and have had great results. I was a little dizzy the first month, but that side effect went away once my body adjusted to the medication. I'm really happy with it!
4Patient Review
1/9/2012
Nortrel 7/7/7 for Painful Periods
I had to take this for a month when my regular birth control got backed up, and it was mostly effective. The main issue I had was that I started getting stomach problems after taking it- even when I ate beforehand. My pharmacist and I think it might have been the coating on the pill, but other than that it seemed to work like normal birth control.
2.3Patient Review
8/21/2012
Nortrel 7/7/7 for Absence of Menstrual Periods
I started taking Nortrel 777 earlier this year and have since then put on some extra weight. My cycle has also been irregular, only coming once a month since June. If anyone could explain why this might be happening, I would appreciate it.
2.3Patient Review
7/6/2017
Nortrel 7/7/7 for Abnormal Bleeding from the Uterus
I started taking this medication for my irregular bleeding, but unfortunately it has only made the problem worse. I'm not sure if I'll continue to use it or not.
1.7Patient Review
8/31/2011
Nortrel 7/7/7 for Birth Control
contraception
1.3Patient Review
1/10/2012
Nortrel 7/7/7 for Birth Control
This medication gave me really terrible PMS. I had a tiny bit of spotting, but no period. This was never an issue for me on other medications, so I know it's not due to pregnancy.
1Patient Review
1/6/2016
Nortrel 7/7/7 for Abnormally Long or Heavy Periods
This drug was incredibly dangerous for me. I had a clot that caused a heart attack.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about nortrel 7/7/7

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does Nortrel 777 have estrogen?

"This contraceptive medication contains a progestin and an estrogen to prevent pregnancy."

Answered by AI

Is Nortrel 777 a good birth control?

"Nortrel 7/7/7 is a birth control medication that has an average rating of 2.8 out of 10 from a total of 17 reviews. 12% of reviewers had a positive experience with the medication, while 76% had a negative experience."

Answered by AI

Does Nortrel 777 cause weight gain?

"The most reported side effects were headache, vaginal candidiasis, nausea, menstrual cramps, breast tenderness, abdominal pain, mood changes, bacterial vaginitis, acne, irregular uterine bleeding, and weight gain."

Answered by AI

What kind of birth control is Nortrel 777?

"Nortrel 7/7/7 is a combination birth control pill that contains different amounts of progestin and estrogen depending on the color of the pill. The pill is taken once a day at the same time every day, and corresponds to a specific time during your menstrual cycle."

Answered by AI

Clinical Trials for Nortrel 7/7/7

Have you considered Nortrel 7/7/7 clinical trials? We made a collection of clinical trials featuring Nortrel 7/7/7, we think they might fit your search criteria.
Have you considered Nortrel 7/7/7 clinical trials? We made a collection of clinical trials featuring Nortrel 7/7/7, we think they might fit your search criteria.
Have you considered Nortrel 7/7/7 clinical trials? We made a collection of clinical trials featuring Nortrel 7/7/7, we think they might fit your search criteria.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top