Nalfon

Pain, Rheumatoid Arthritis, Osteoarthritis + 1 more
Treatment
5 FDA approvals
20 Active Studies for Nalfon

What is Nalfon

FenoprofenThe Generic name of this drug
Treatment SummaryIbuprofen is a pain relief and fever-reducing medication that is similar to aspirin but causes fewer stomach problems. It binds to proteins in the bloodstream and helps reduce inflammation.
Nalfonis the brand name
image of different drug pills on a surface
Nalfon Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Nalfon
Fenoprofen
2006
38

Approved as Treatment by the FDA

Fenoprofen, also known as Nalfon, is approved by the FDA for 5 uses which include Osteoarthritis (OA) and Mild pain .
Osteoarthritis (OA)
Mild pain
Helps manage Mild pain
Osteoarthritis
Rheumatoid Arthritis
Pain
Helps manage moderate Pain

Effectiveness

How Nalfon Affects PatientsFenoprofen is a medicine used to reduce pain, inflammation, and fever. It works by stopping the production of enzymes needed for inflammation. In patients with rheumatoid arthritis and osteoarthritis, it has been shown to be just as effective as aspirin in reducing symptoms like pain, stiffness, swelling, and overall disease activity. It has been found to cause fewer side effects such as nausea, indigestion, ringing in the ears, and stomach ulcers than aspirin. In patients with pain, it has been shown to reduce pain levels, improve overall pain relief, and provide long-lasting pain relief.
How Nalfon works in the bodyWe don't know exactly how fenoprofen works, but it likely works by blocking a specific enzyme in the body that helps make prostaglandins. Studies have shown that it can block this enzyme when it is taken from cows.

When to interrupt dosage

The advised dosage of Nalfon is governed by the diagnosed condition, such as Pain, Osteoarthritis (OA) and Rheumatoid Arthritis. The quantity of dosage fluctuates, contingent upon the technique of delivery illustrated in the table beneath.
Condition
Dosage
Administration
Osteoarthritis
, 600.0 mg, 400.0 mg, 300.0 mg, 200.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral
Mild pain
, 600.0 mg, 400.0 mg, 300.0 mg, 200.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral
Pain
, 600.0 mg, 400.0 mg, 300.0 mg, 200.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral
Rheumatoid Arthritis
, 600.0 mg, 400.0 mg, 300.0 mg, 200.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral

Warnings

Nalfon Contraindications
Condition
Risk Level
Notes
Coronary Artery Bypass Grafting
Do Not Combine
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Nalfon.
Common Nalfon Drug Interactions
Drug Name
Risk Level
Description
Macimorelin
Major
The therapeutic efficacy of Macimorelin can be decreased when used in combination with Fenoprofen.
Methotrexate
Major
The serum concentration of Methotrexate can be increased when it is combined with Fenoprofen.
Mifamurtide
Major
The therapeutic efficacy of Mifamurtide can be decreased when used in combination with Fenoprofen.
Neomycin
Major
The risk or severity of nephrotoxicity can be increased when Fenoprofen is combined with Neomycin.
Omacetaxine mepesuccinate
Major
The risk or severity of bleeding can be increased when Fenoprofen is combined with Omacetaxine mepesuccinate.
Nalfon Toxicity & Overdose RiskSymptoms of an NSAID overdose may start within several hours and can include indigestion, nausea, vomiting, stomach pain, dizziness, headache, unsteady gait, ringing in the ears, trembling, drowsiness, and disorientation. In rare cases, patients may experience high fever, rapid heartbeat, low blood pressure, kidney failure, or shallow breathing and too much acid in the blood.
image of a doctor in a lab doing drug, clinical research

Nalfon Novel Uses: Which Conditions Have a Clinical Trial Featuring Nalfon?

75 active clinical trials are currently in progress to investigate the potential of Nalfon to reduce symptoms of Rheumatoid Arthritis, Pain and Mild Pain.
Condition
Clinical Trials
Trial Phases
Pain
0 Actively Recruiting
Osteoarthritis
0 Actively Recruiting
Mild pain
0 Actively Recruiting
Rheumatoid Arthritis
54 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1

Nalfon Reviews: What are patients saying about Nalfon?

5Patient Review
7/11/2009
Nalfon for Pain
I would highly recommend this NSAID to anyone. I'm a retired nurse and took this medication for all my aches and pains. It's the best one I've found, but unfortunately it's tough to find the generic version.
4.3Patient Review
1/31/2010
Nalfon for Arthritis
I was in a car accident some time ago and have since developed arthritis from the surgeries I needed afterwards. Celebrex didn't do much for me, but after taking this medication for just three weeks I can already tell it's working better. This treatment allows me to live my life more normally again.
4Patient Review
10/12/2011
Nalfon for Joint Damage causing Pain and Loss of Function
I've been using this on and off for 15 years. I find it to be less harsh on my body than hydrocordone, and it does a fairly good job of relieving my pain.
4Patient Review
12/10/2008
Nalfon for Arthritis
I've been dealing with some pretty bad swelling and arthritis pain in my feet for a while now. This treatment has really helped me to get by without needing surgery (at least for now). I take 600 mg 3 times a day, and it helps me walk with only moderate pain.
4Patient Review
10/20/2009
Nalfon for Pain
Nalfon has been hugely effective for my plantar fasciitis. The pain is nearly gone and I can walk without limping. My doctor told me to take it after eating because it would upset my stomach, and he was right!
3.7Patient Review
1/10/2008
Nalfon for Pain
I've been on this medication for eight days now, and my doctor tells me I have to take it for another eight. They also gave me two cortisone shots. It's hard to say whether or not the medicine is working because of the other factors at play, but I haven't seen a significant difference so far.
2.7Patient Review
2/16/2010
Nalfon for Pain
I took this medication for two weeks as directed, but saw no improvement in my heel spur. However, I did notice that my arthritis pain was significantly reduced while taking this medication.
1Patient Review
12/9/2007
Nalfon for Pain
I was taking the medication for heel spurs, but I ended up throwing up four times. Clearly, this wasn't the right treatment for me.
1Patient Review
4/3/2009
Nalfon for Arthritis
I had a severe allergic reaction to this drug and it was very scary.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about nalfon

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What type of drug is Nalfon?

"This medication falls into the category of nonsteroidal anti-inflammatory drugs (NSAIDs). If you have a chronic condition such as arthritis, talk to your doctor about non-medication treatments and/or using other medication to manage your pain."

Answered by AI

What is Nalfon used for?

"Both Nalfon and Advil are NSAIDs that work to relieve pain and diminish inflammation. Only Nalfon requires a prescription, whereas Advil is available both with and without a prescription."

Answered by AI

What is fenoprofen 600 mg used for?

"Fenoprofen is a nonsteroidal anti-inflammatory drug that is used to treat mild to moderate pain. It can also help relieve symptoms of arthritis, such as inflammation, swelling, stiffness, and joint pain."

Answered by AI

How often can you take Nalfon?

"The recommended dose of 400 to 600 mg should be given orally 3 or 4 times a day to relieve signs and symptoms of rheumatoid arthritis or osteoarthritis. The dose may be increased or decreased depending on the severity of the symptoms."

Answered by AI

Clinical Trials for Nalfon

Image of Weill Cornell Medical College in New York, United States.

Health Coaching for Rheumatoid Arthritis

18+
All Sexes
New York, NY
The goal of this clinical trial is to learn if peer coaching works to reduce levels of anxiety and/or depression in adults diagnosed with Rheumatoid Arthritis (RA). The main questions it aims to answer are: Do people with RA who complete the intervention with a peer coach have lower levels of anxiety and/or depression at 6 months from baseline? Do people with RA who complete the intervention with a peer coach have lower levels of anxiety and/or depression at 6 months compared to those in the control arm? Researchers will compare the peer coaching intervention to an active-control arm (where people without RA coach participants on general health and nutrition topics) to see if peer coaching works to reduce anxiety and/or depression. Participants will meet with a coach every week for 9 weeks and complete several surveys before, during and after the intervention
Recruiting
Has No Placebo
Weill Cornell Medical CollegeIris Y Navarro-Millán, MDBristol-Myers Squibb
Image of Humana Healthcare Research, Inc. in Louisville, United States.

Academic Detailing for Rheumatoid Arthritis

Any Age
All Sexes
Louisville, KY
The goal of this trial is to learn if an interactive evidence-based educational outreach visits to clinicians who prescribe biologics change prescribing of biosimilar medications. The main questions it aims to answer are: 1. Do educational outreach visits lead to a higher number of prescriptions for biosimilar versions of adalimumab? 2. Do in-person or virtual visits work better? Researchers will compare clinicians offered the educational outreach visit to those who are not offered the visit to see if there is a difference in prescribing of biosimilar versions of adalimumab instead of the original brand-name version. Participants will be offered the chance to meet with a trained clinician who will provide educational information tailored to their knowledge and attitudes on the topic. They will also be provided an educational brochure and patient educational materials.
Waitlist Available
Has No Placebo
Humana Healthcare Research, Inc. (+1 Sites)
Image of Truway Health, Inc. www.truwayhealth.com (401 E 34th Street, S11P, New York, NY 10016) in New York, United States.

Electromagnetic Resonance Therapy for Autoimmune Diseases

Any Age
All Sexes
New York, NY
The ImmuneNet study is a Phase I/II clinical trial sponsored by Truway Health, Inc. It will test whether gentle, low-frequency electromagnetic resonance (LF-EMR) can influence how immune cells communicate and synchronize with each other. The goal is to see if this "quantum-synaptic" signaling effect can help stabilize immune activity and reduce the number of autoimmune flare-ups in people living with conditions such as lupus, rheumatoid arthritis, or multiple sclerosis. Participants will receive either an active or a sham (placebo) LF-EMR session three times per week for twelve weeks. Each session is completely non-invasive. Blood samples will be collected to study cytokines (immune-system messenger molecules), gene-expression patterns, and electrical field coherence among immune cells. A machine-learning system will analyze these data to predict inflammation patterns and guide individualized treatment settings. All participant data will be securely recorded and time-stamped to ensure transparency and privacy. The expected outcome of the study is a measurable reduction in autoimmune flare frequency and symptom severity, along with improved understanding of how electromagnetic signaling might safely regulate immune function.
Phase 1 & 2
Waitlist Available
Truway Health, Inc. www.truwayhealth.com (401 E 34th Street, S11P, New York, NY 10016)Gavin Solomon, President & CEOTruway Health, Inc.
Image of University of Minnesota Medical School, Division of Rheumatic and Autoimmune Diseases in Minneapolis, United States.

Ultrasound Therapy for Rheumatoid Arthritis

18+
All Sexes
Minneapolis, MN
The At-Home ULTRA Study will evaluate performance of the MINI system as indicated for the treatment of adults with active, moderate to severe rheumatoid arthritis who are inadequate responders or are intolerant to conventional synthetic disease-modifying anti-rheumatic drugs (csDMARDs), biologic DMARDs (bDMARDs), or targeted synthetic DMARDs (tsDMARDs). The non-invasive study device delivers ultrasound stimulation to the spleen to reduce inflammation. The study will enroll at least 60 participants at up to 8 sites. There will be three arms consisting of two active stimulation groups (treatment) and one non-active stimulation group (sham-control). After completing the double-blinded primary endpoint assessment period at Week 12, there will be a one-way crossover of control participants to active stimulation and an additional 12 week follow-up with all participants to evaluate long-term outcomes.
Recruiting
Drug
University of Minnesota Medical School, Division of Rheumatic and Autoimmune DiseasesHubert LimSecondWave Systems Inc.
Have you considered Nalfon clinical trials? We made a collection of clinical trials featuring Nalfon, we think they might fit your search criteria.Go to Trials
Image of St. Lawrence Health in Potsdam, United States.

Primary Care for Rheumatoid Arthritis

18+
All Sexes
Potsdam, NY
Rheumatoid arthritis (RA) is a complex autoimmune disease where the immune system attacks healthy joint tissue; causing pain, swelling, and stiffness of the joints. This disease effects lots of people in the US and can lead to major joint damage if not properly treated. In rural areas like northern NY, these are underserved areas for RA patients, thus many patients struggle to get the appropriate care. This model is testing whether primary care providers (PCP) can safely and effectively provide stable RA patients with the proper treatment rather than send them to a specialist. PCPs were trained through classes, case reviews, and a final exam. Patients will be randomly assigned to either see a trained PCP or their normal rheumatologist at the rheumatology clinic. This study will examine how patients are doing over a year using medical exams and patient feedback. If this model proves to be successful, it will make RA treatment easier and more affordable for patients.
Recruiting
Has No Placebo
St. Lawrence HealthEyal Kedar, MD
Image of Pender Community Health Centre in Vancouver, Canada.

Personalized Outreach for Rheumatic Diseases

18+
All Sexes
Vancouver, Canada
The primary goal of this study is to determine whether providing patient honoraria and/or outreach services can improve the attendance rate of appointments at an inner city rheumatology clinic in Vancouver, British Columbia. The main question it aims to answer are: * Does providing a financial honorarium ($20 for each follow-up appointment with completed bloodwork) improve attendance rate at an inner city rheumatology clinic? * Does providing a personalized outreach service for rheumatic diseases improve attendance rate at an inner city rheumatology clinic? The researchers will compare providing patient honoraria to providing both honoraria and outreach services, and compare each of these to the regular appointment schedule without honoraria or outreach. Participants will: * Undergo randomization to receive honoraria or honoraria and outreach services together * Complete surveys about their health and understanding of their rheumatic disease at baseline, 3-month, and 6-month intervals * Visit the clinic every month for check-ups and monitoring bloodwork if they are started on immunosuppressants for their condition
Waitlist Available
Has No Placebo
Pender Community Health CentreBrent R Ohata, MD
Have you considered Nalfon clinical trials? We made a collection of clinical trials featuring Nalfon, we think they might fit your search criteria.Go to Trials
Have you considered Nalfon clinical trials? We made a collection of clinical trials featuring Nalfon, we think they might fit your search criteria.Go to Trials
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